Tumor-selective vessel occlusions by platelets after vascular targeting chemotherapy using paclitaxel encapsulated in cationic liposomes

International Journal of Cancer

Volumn 122, Issue 2, 2008, Pages 452-460

  Strieth, Sebastian ^a,b   Nussbaum, Claudia F ^a   Eichhorn, Martin E ^a   Fuhrmann, Martin ^b   Teifel, Michael ^c   Michaelis, Uwe ^d   Berghaus, Alexander ^b   Dellian, Marc ^a,b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c Zentaris GmbH   (Germany)

^d MediGene AG   (Germany)

Author keywords

Angiogenesis; Coagulation system; In vivo imaging; Mechanisms of drug action; Novel drug delivery systems; Platelet; Tumor microcirculation; Vascular targeting

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; CATION; DIOLEOYLPHOSPHATIDYLCHOLINE; LIPOSOME; PACLITAXEL; VASCULAR TARGETING AGENT;

AMELANOTIC MELANOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING; BLOOD VESSEL OCCLUSION; CELL INTERACTION; CONFOCAL LASER MICROSCOPY; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG DOSAGE FORM COMPARISON; DRUG EFFECT; DRUG MECHANISM; ENCAPSULATION; ENDOTHELIUM CELL; FLUORESCENCE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROCIRCULATION; MICROTHROMBUS; NONHUMAN; PRIORITY JOURNAL; REPEATED DRUG DOSE; SYRIAN HAMSTER; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; TISSUE PERFUSION; TUMOR VASCULARIZATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOOD PLATELETS; CRICETINAE; DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; FLOW CYTOMETRY; LIPOSOMES; MESOCRICETUS; MICROCIRCULATION; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; PACLITAXEL; PLATELET ADHESIVENESS;

EID: 36849081545     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23088     Document Type: Article

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