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Volumn 134, Issue 2, 2008, Pages 193-201

Relationship between VEGF and p53 expression and tumor cell proliferation in human gastrointestinal carcinomas

Author keywords

Clinicopathological factors; Gastrointestinal carcinomas; Immunohistochemistry; p53; PCNA; VEGF

Indexed keywords

CYCLINE; PROTEIN P53; VASCULOTROPIN;

EID: 36849057578     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-007-0270-5     Document Type: Article
Times cited : (28)

References (60)
  • 1
    • 17944365210 scopus 로고    scopus 로고
    • P53 nuclear accumulation and multiploidy are adverse prognostic factors in surgically resected stage II colorectal cancers independent of fluorouracil-based adjuvant therapy
    • Buglioni S, D'Agnano I, Vasselli S, Perrone R, D'Angelo C, Brenna A, Benevolo M, Cosimelli M, Zupi G, Mottolese M (2001) p53 nuclear accumulation and multiploidy are adverse prognostic factors in surgically resected stage II colorectal cancers independent of fluorouracil-based adjuvant therapy. Am J Clin Pathol 116:360-368
    • (2001) Am J Clin Pathol , vol.116 , pp. 360-368
    • Buglioni, S.1    D'Agnano, I.2    Vasselli, S.3    Perrone, R.4    D'Angelo, C.5    Brenna, A.6    Benevolo, M.7    Cosimelli, M.8    Zupi, G.9    Mottolese, M.10
  • 6
    • 0033998238 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in human colon cancer: Biology and therapeutic implications
    • Ellis LM, Takahashi Y, Liu W, Shaheen RM (2000) Vascular endothelial growth factor in human colon cancer: biology and therapeutic implications. Oncologist 1:11-15
    • (2000) Oncologist , vol.1 , pp. 11-15
    • Ellis, L.M.1    Takahashi, Y.2    Liu, W.3    Shaheen, R.M.4
  • 8
    • 4243494385 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in regulation of angiogenesis
    • Humana Press Totowa, New Jersey
    • Ferrara N (1999) Role of vascular endothelial growth factor in regulation of angiogenesis. In: Teicher BA (ed) Antiangiogenic agents in cancer therapy. Humana Press, Totowa, New Jersey, pp 119-141
    • (1999) Antiangiogenic Agents in Cancer Therapy , pp. 119-141
    • Ferrara, N.1    Teicher, B.A.2
  • 9
    • 0002614542 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor in angiogenesis
    • Marcel Dekker New York, Basel
    • Ferrara N (2000) The role of vascular endothelial growth factor in angiogenesis. In: Rubanyi GM (ed) Angiogenesis in health and disease. Marcel Dekker, New York, Basel, pp 47-73
    • (2000) Angiogenesis in Health and Disease , pp. 47-73
    • Ferrara, N.1    Rubanyi, G.M.2
  • 10
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Basic science and clinical progress
    • Ferrara N (2004) Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 25:581-611
    • (2004) Endocr Rev , vol.25 , pp. 581-611
    • Ferrara, N.1
  • 11
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 12
    • 0015008620 scopus 로고
    • Isolation of a tumor factor responsible for angiogenesis
    • Folkman J, Merler E, Abernathy C, Williams G (1971) Isolation of a tumor factor responsible for angiogenesis. J Exp Med 133:275-288
    • (1971) J Exp Med , vol.133 , pp. 275-288
    • Folkman, J.1    Merler, E.2    Abernathy, C.3    Williams, G.4
  • 14
    • 18244364180 scopus 로고    scopus 로고
    • A high vascular count and overexpression of vascular endothelial growth factor are associated with unfavourable prognosis in operated small cell lung carcinoma
    • Fontanini G, Faviana P, Lucchi M, Boldrini L, Mussi A, Camacci T, Mariani MA, Angeletti CA, Basolo F, Pingitore R (2002) A high vascular count and overexpression of vascular endothelial growth factor are associated with unfavourable prognosis in operated small cell lung carcinoma. Br J Cancer 86:558-563
    • (2002) Br J Cancer , vol.86 , pp. 558-563
    • Fontanini, G.1    Faviana, P.2    Lucchi, M.3    Boldrini, L.4    Mussi, A.5    Camacci, T.6    Mariani, M.A.7    Angeletti, C.A.8    Basolo, F.9    Pingitore, R.10
  • 16
    • 0036242150 scopus 로고    scopus 로고
    • Frequent phosporylation at serine 392 in overexpressed p53 protein due to missense mutation in carcinoma of the urinary tract
    • Furihala M, Kurabayashl A, Matsumoto M, Sonobe H, Ohtsuki Y, Lerao N, Kuwahara M, Shuin T (2002) Frequent phosporylation at serine 392 in overexpressed p53 protein due to missense mutation in carcinoma of the urinary tract. J Pathol 197:82-88
    • (2002) J Pathol , vol.197 , pp. 82-88
    • Furihala, M.1    Kurabayashl, A.2    Matsumoto, M.3    Sonobe, H.4    Ohtsuki, Y.5    Lerao, N.6    Kuwahara, M.7    Shuin, T.8
  • 18
    • 36849018871 scopus 로고    scopus 로고
    • Roles of p53 in carcinogenesis, diagnosis and treatment of hepatocellular carcinoma
    • Guan Y-H, He Q, La Z (2006) Roles of p53 in carcinogenesis, diagnosis and treatment of hepatocellular carcinoma. J Cancer Mol 2:191-197
    • (2006) J Cancer Mol , vol.2 , pp. 191-197
    • Guan, Y.-H.1    He, Q.2    La, Z.3
  • 20
    • 0037141345 scopus 로고    scopus 로고
    • Intratumoral microvessel density in human solid tumors
    • Hasan J, Byersm R, Jayson GC (2002) Intratumoral microvessel density in human solid tumors. Cancer Res 86:1566-1577
    • (2002) Cancer Res , vol.86 , pp. 1566-1577
    • Hasan, J.1    Byersm, R.2    Jayson, G.C.3
  • 21
    • 0037191916 scopus 로고    scopus 로고
    • Deconstruction of p53 functions and regulation
    • Haupt Y, Robles A, Prives C, Rotter V (2002) Deconstruction of p53 functions and regulation. Oncogene 21:8223-8231
    • (2002) Oncogene , vol.21 , pp. 8223-8231
    • Haupt, Y.1    Robles, A.2    Prives, C.3    Rotter, V.4
  • 23
    • 0034655306 scopus 로고    scopus 로고
    • Implication of vascular endothelial growth factor and p53 status for angiogenesis in non-invasive colorectal carcinoma
    • Kondo Y, Arii S, Furutani M, Isigami S, Mori A, Onodera H, Chiba T, Imamura M (2000) Implication of vascular endothelial growth factor and p53 status for angiogenesis in non-invasive colorectal carcinoma. Cancer 88:1820-1827
    • (2000) Cancer , vol.88 , pp. 1820-1827
    • Kondo, Y.1    Arii, S.2    Furutani, M.3    Isigami, S.4    Mori, A.5    Onodera, H.6    Chiba, T.7    Imamura, M.8
  • 24
    • 0041475685 scopus 로고    scopus 로고
    • Prognostic predictors of gastrointestinal stromal tumors: A multi-institutional analysis of 102 patients with definition of a prognostic index
    • Kontogianni K, Demonakou M, Kavantzas N, Lazaris ACh, Lariou K, Vourlakou C, Davaris P (2003) Prognostic predictors of gastrointestinal stromal tumors: a multi-institutional analysis of 102 patients with definition of a prognostic index. Eur J Surg Oncol 29:548-556
    • (2003) Eur J Surg Oncol , vol.29 , pp. 548-556
    • Kontogianni, K.1    Demonakou, M.2    Kavantzas, N.3    Ach, L.4    Lariou, K.5    Vourlakou, C.6    Davaris, P.7
  • 26
    • 0037258782 scopus 로고    scopus 로고
    • Localization of vascular endothelial growth factor and its receptors in digestive endocrine tumors: Correlation with microvessel density and clinicopathologic features
    • La Rosa S, Uccella S, Finzi G, Albarello L, Sessa F, Capella C (2003) Localization of vascular endothelial growth factor and its receptors in digestive endocrine tumors: correlation with microvessel density and clinicopathologic features. Hum Pathol 34:18-27
    • (2003) Hum Pathol , vol.34 , pp. 18-27
    • La Rosa, S.1    Uccella, S.2    Finzi, G.3    Albarello, L.4    Sessa, F.5    Capella, C.6
  • 27
    • 0037192694 scopus 로고    scopus 로고
    • P53 and recombination intermediates: Role of tetramerization at DNA junctions in complex formation and exonucleotic degradation
    • Lanz C, Süsse S, Wies Müller L (2002) p53 and recombination intermediates: role of tetramerization at DNA junctions in complex formation and exonucleotic degradation. Oncogene 21:2130-2140
    • (2002) Oncogene , vol.21 , pp. 2130-2140
    • Lanz, C.1    Süsse, S.2    Wies Müller, L.3
  • 28
    • 0036153808 scopus 로고    scopus 로고
    • VEGF and bFGF are highly expressed in intraluminal fibromyxoid lesions in bronchiolitis obliterans organizing pneumonia
    • Lappi-Blanco E, Soini Y, Kinnula V, Pääkkö P (2002) VEGF and bFGF are highly expressed in intraluminal fibromyxoid lesions in bronchiolitis obliterans organizing pneumonia. J Pathol 196:220-227
    • (2002) J Pathol , vol.196 , pp. 220-227
    • Lappi-Blanco, E.1    Soini, Y.2    Kinnula, V.3    Pääkkö, P.4
  • 29
    • 0141649200 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in salivary gland carcinomas and its relation to p53, Ki-67 and prognosis
    • Lim J, Kang S, Llee M, Pal H, Yoon H, Lee J, Hong S, Lim C (2003) Expression of vascular endothelial growth factor in salivary gland carcinomas and its relation to p53, Ki-67 and prognosis. J Oral Pathol Med 32:552-561
    • (2003) J Oral Pathol Med , vol.32 , pp. 552-561
    • Lim, J.1    Kang, S.2    Llee, M.3    Pal, H.4    Yoon, H.5    Lee, J.6    Hong, S.7    Lim, C.8
  • 30
    • 0026683110 scopus 로고
    • Clinical application of morphologic and immunocytochemical assessments of cell proliferation
    • Linden M, Torres F, Kubus J, Zarbo R (1992) Clinical application of morphologic and immunocytochemical assessments of cell proliferation. Am J Clin Pathol 97:S4-S13
    • (1992) Am J Clin Pathol , vol.97
    • Linden, M.1    Torres, F.2    Kubus, J.3    Zarbo, R.4
  • 32
    • 0031725558 scopus 로고    scopus 로고
    • Expression of p53 and vascular endothelial growth factor associated with tumor angiogenesis and prognosis in gastric cancer
    • Maeda K, Kang S-M, Onoda N, Ogawa M, Sawada T, Nakata B, Kato Y, Chung Y-S, Sowa M (1998a) Expression of p53 and vascular endothelial growth factor associated with tumor angiogenesis and prognosis in gastric cancer. Oncology 55:594-599
    • (1998) Oncology , vol.55 , pp. 594-599
    • Maeda, K.1    Kang, S.-M.2    Onoda, N.3    Ogawa, M.4    Sawada, T.5    Nakata, B.6    Kato, Y.7    Chung, Y.-S.8    Sowa, M.9
  • 33
    • 0031783641 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in human oral squamous cell carcinoma: Its association with tumor progression and p53 status
    • Maeda T, Matsumura S, Hiranuma H (1998b) Expression of vascular endothelial growth factor in human oral squamous cell carcinoma: its association with tumor progression and p53 status. J Clin Pathol 51:771-775
    • (1998) J Clin Pathol , vol.51 , pp. 771-775
    • Maeda, T.1    Matsumura, S.2    Hiranuma, H.3
  • 34
    • 0033566969 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression in preoperative biopsy specimens correlates with disease recurrence in patients with early gastric carcinoma
    • Maeda K, Kang S-M, Onoda N, Ogawa M, Sawada T, Kato Y, Chung Y-S (1999) Vascular endothelial growth factor expression in preoperative biopsy specimens correlates with disease recurrence in patients with early gastric carcinoma. Am Cancer Soc 86:566-571
    • (1999) Am Cancer Soc , vol.86 , pp. 566-571
    • Maeda, K.1    Kang, S.-M.2    Onoda, N.3    Ogawa, M.4    Sawada, T.5    Kato, Y.6    Chung, Y.-S.7
  • 35
    • 0032983645 scopus 로고    scopus 로고
    • Prognostic value of p53 protein expression for patients with gastric cancer-a multivariate analysis
    • Maehara Y, Tomoda M, Hasuda S, Kabashima A, Tokunaga E, Kakeji Y, Sugimachi K (1999) Prognostic value of p53 protein expression for patients with gastric cancer-a multivariate analysis. Br J Cancer 79:1255-1261
    • (1999) Br J Cancer , vol.79 , pp. 1255-1261
    • Maehara, Y.1    Tomoda, M.2    Hasuda, S.3    Kabashima, A.4    Tokunaga, E.5    Kakeji, Y.6    Sugimachi, K.7
  • 37
    • 0034860191 scopus 로고    scopus 로고
    • Tumor growth patterns and biological characteristics of early gastric carcinoma
    • Maehara Y, Kakeji Y, Oda S, Baba H, Sugimachi K (2001) Tumor growth patterns and biological characteristics of early gastric carcinoma. Oncology 61:102-112
    • (2001) Oncology , vol.61 , pp. 102-112
    • Maehara, Y.1    Kakeji, Y.2    Oda, S.3    Baba, H.4    Sugimachi, K.5
  • 40
    • 0032920520 scopus 로고    scopus 로고
    • Tumour markers of prognosis in colorectal cancer
    • McLeod HL, Murray GI (1999) Tumour markers of prognosis in colorectal cancer. Br J Cancer 79:191-203
    • (1999) Br J Cancer , vol.79 , pp. 191-203
    • McLeod, H.L.1    Murray, G.I.2
  • 42
    • 0037126383 scopus 로고    scopus 로고
    • Stabilization of p53 and transactivation of its target genes in response to replication blockade
    • Nayak B, Das G (2002) Stabilization of p53 and transactivation of its target genes in response to replication blockade. Oncogene 21:7226-7229
    • (2002) Oncogene , vol.21 , pp. 7226-7229
    • Nayak, B.1    Das, G.2
  • 43
    • 0033844047 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor is a potential biomarker of metastatic recurrence after curative resection of hepatocellular carcinoma
    • Niu Q, Tang ZY, Ma ZC, Qin LX, Zhang LH (2000) Serum vascular endothelial growth factor is a potential biomarker of metastatic recurrence after curative resection of hepatocellular carcinoma. World J Gastroenterol 6:565-568
    • (2000) World J Gastroenterol , vol.6 , pp. 565-568
    • Niu, Q.1    Tang, Z.Y.2    Ma, Z.C.3    Qin, L.X.4    Zhang, L.H.5
  • 44
    • 0036968039 scopus 로고    scopus 로고
    • Combined evaluation of expressions of p53 and p21 proteins as prognostic factors for patients with gastric carcinoma
    • Okuyama T, Maehara Y, Kabashima A, Takahashi I, Kakeji Y, Sugimachi K (2002) Combined evaluation of expressions of p53 and p21 proteins as prognostic factors for patients with gastric carcinoma. Oncology 63:353-361
    • (2002) Oncology , vol.63 , pp. 353-361
    • Okuyama, T.1    Maehara, Y.2    Kabashima, A.3    Takahashi, I.4    Kakeji, Y.5    Sugimachi, K.6
  • 45
    • 33847609317 scopus 로고    scopus 로고
    • The detection of serum anti-p53 antibodies from patients with gastric carcinoma in China
    • Qiu L-L, Hua P-Y, Ye LL, Wang YC, Qiu T, Bao HZ, Wang L (2007) The detection of serum anti-p53 antibodies from patients with gastric carcinoma in China. Cancer Det Prev 31:45-49
    • (2007) Cancer Det Prev , vol.31 , pp. 45-49
    • Qiu, L.-L.1    Hua, P.-Y.2    Ye, L.L.3    Wang, Y.C.4    Qiu, T.5    Bao, H.Z.6    Wang, L.7
  • 47
    • 0042063900 scopus 로고    scopus 로고
    • Prognostic value of p53 protein expression and vascular endothelial growth factor expression in resected squamous cell carcinoma of the esophagus
    • Rosa AR, Schirmer CC, Gurski RR, Meurer L, Edelweiss MI, Kruel CD (2003) Prognostic value of p53 protein expression and vascular endothelial growth factor expression in resected squamous cell carcinoma of the esophagus. Dis Esophagus 16:112-118
    • (2003) Dis Esophagus , vol.16 , pp. 112-118
    • Rosa, A.R.1    Schirmer, C.C.2    Gurski, R.R.3    Meurer, L.4    Edelweiss, M.I.5    Kruel, C.D.6
  • 49
    • 0032818878 scopus 로고    scopus 로고
    • Neoangiogenesis and relationship to nuclear p53 accumulation and vascular endothelial growth factor expression in advanced gastric carcinoma
    • Saito H, Tujitani S, Ikegichu M, Maeta M, Kaibara N (1999) Neoangiogenesis and relationship to nuclear p53 accumulation and vascular endothelial growth factor expression in advanced gastric carcinoma. Oncology 57:164-172
    • (1999) Oncology , vol.57 , pp. 164-172
    • Saito, H.1    Tujitani, S.2    Ikegichu, M.3    Maeta, M.4    Kaibara, N.5
  • 51
    • 3242664194 scopus 로고    scopus 로고
    • Tumor angiogenesis: A pathologist's point of view
    • Scoazec J-Y (2000) Tumor angiogenesis: a pathologist's point of view. Elect J Oncol 2:23-32
    • (2000) Elect J Oncol , vol.2 , pp. 23-32
    • Scoazec, J.-Y.1
  • 52
    • 0030035991 scopus 로고    scopus 로고
    • Prognostic significance of p53 overexpression and mutation in colorectal adenocarcinomas
    • Smith DR, Ji C-Y, Goh H-S (1996) Prognostic significance of p53 overexpression and mutation in colorectal adenocarcinomas. Br J Cancer 74:216-223
    • (1996) Br J Cancer , vol.74 , pp. 216-223
    • Smith, D.R.1    Ji, C.-Y.2    Goh, H.-S.3
  • 53
    • 0034009675 scopus 로고    scopus 로고
    • Expression of CD44, vascular endothelial growth factor, and proliferating cell nuclear antigen in severe venous invasional colorectal cancer and its relationship to liver metastasis
    • Sumiyoshi Y, Yamashita Y, Maekawa T, Sakai N, Shirakusa T, Kikuchi M (2000) Expression of CD44, vascular endothelial growth factor, and proliferating cell nuclear antigen in severe venous invasional colorectal cancer and its relationship to liver metastasis. Surg Today 30:323-327
    • (2000) Surg Today , vol.30 , pp. 323-327
    • Sumiyoshi, Y.1    Yamashita, Y.2    Maekawa, T.3    Sakai, N.4    Shirakusa, T.5    Kikuchi, M.6
  • 54
    • 0032548970 scopus 로고    scopus 로고
    • P53, vessel count, and vascular endothelial growth factor expression in human colon cancer
    • Takahashi Y, Bucana CD, Cleary KR, Ellis LM (1998) p53, vessel count, and vascular endothelial growth factor expression in human colon cancer. Int J Cancer 79:34-38
    • (1998) Int J Cancer , vol.79 , pp. 34-38
    • Takahashi, Y.1    Bucana, C.D.2    Cleary, K.R.3    Ellis, L.M.4
  • 55
    • 0344375087 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach
    • Takahashi R, Tanaka S, Kitadai Y, Sumii M, Yoshihara M, Haruma K, Chayama K (2003) Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach. Oncology 64:266-274
    • (2003) Oncology , vol.64 , pp. 266-274
    • Takahashi, R.1    Tanaka, S.2    Kitadai, Y.3    Sumii, M.4    Yoshihara, M.5    Haruma, K.6    Chayama, K.7
  • 57
    • 0031784318 scopus 로고    scopus 로고
    • Proliferation markers in tumours: Interpretation and clinical value
    • van Diest PJ, Brugal G, Baak JP (1998) Proliferation markers in tumours: interpretation and clinical value. J Clin Pathol 51:716-724
    • (1998) J Clin Pathol , vol.51 , pp. 716-724
    • Van Diest, P.J.1    Brugal, G.2    Baak, J.P.3
  • 59
    • 0033754806 scopus 로고    scopus 로고
    • Lung cancer proliferation correlates with (F-18) fluorodeoxyglucose uptake by positron emission tomography
    • Vesselle H, Schmidt R, Pugsley JM, Li M, Kohlmyer SG, Vallires E, Wood DE (2000) Lung cancer proliferation correlates with (F-18) fluorodeoxyglucose uptake by positron emission tomography. Clin Cancer Res 6:3837-3844
    • (2000) Clin Cancer Res , vol.6 , pp. 3837-3844
    • Vesselle, H.1    Schmidt, R.2    Pugsley, J.M.3    Li, M.4    Kohlmyer, S.G.5    Vallires, E.6    Wood, D.E.7
  • 60


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