Tumour proliferation, angiogenesis, and ploidy status in human colon cancer

Journal of Clinical Pathology

Volumn 58, Issue 11, 2005, Pages 1170-1174

  Cristi, E ^b   Perrone, G ^a,b   Toscano, G ^c   Verzi A ^b   Nori, S ^b   Santini, D ^d   Tonini, G ^d   Vetrani, A ^e   Fabiano, A ^c   Rabitti, C ^b  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^b Surgical Pathology   (Italy)

^c FATEBENEFRATELLI HOSPITAL   (Italy)

^d Medical Oncology   (Italy)

^e UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CELL CYCLE S PHASE; CELL PROLIFERATION; COLON CANCER; FLOW CYTOMETRY; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROVASCULATURE; PLOIDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH;

ADULT; AGED; AGED, 80 AND OVER; CELL PROLIFERATION; COLONIC NEOPLASMS; DNA, NEOPLASM; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; PLOIDIES; S PHASE; TUMOR SUPPRESSOR PROTEIN P53; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VON WILLEBRAND FACTOR;

EID: 27644593800     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.2004.025536     Document Type: Article

References (32)

1. Folkman J, Klagsbrun M. Angiogenic factors. Science 1987;235:442-7.
2. Weidner N, Semple JP, Welch WR, et al. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 1991;324:1-8.
3. Macchiarini P, Fontanini G, Hardin MJ, et al. Relation of neovascularisation to metastasis of non-small-cell lung cancer. Lancet 1992;340:145-6.
4. Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-6.
5. Kondo Y, Arii S, Mori A, et al. Enhancement of angiogenesis, tumor growth, and metastasis by transfection of vascular endothelial growth factor into LoVo human colon cancer cell line. Clin Cancer Res 2000;6:622-30.
6. Mattern J, Koomagi R, Volm M. Biological characterization of subgroups of squamous cell lung carcinomas. Clin Cancer Res 1999;5:1459-63.
7. Matsushima H, Goto T, Hosaka Y, et al. Correlation between proliferation, apoptosis, and angiogenesis in prostate carcinoma and their relation to androgen ablation. Cancer 1999;85:1822-7.
8. Charpin C, Devictor B, Bergeret D, et al. CD31 quantitative immunocytochemical assays in breast carcinomas. Correlation with current prognostic factors. Am J Clin Pathol 1995;103:443-8.
9. Giatromanolaki A, Koukourakis MI, Kakolyris S, et al. Vascular endothelial growth factor, wild-type p53, and angiogenesis in early operable non-small cell lung cancer. Clin Cancer Res 1998;4:3017-24.
10. Turner HE, Nagy Z, Gatter KC, et al. Proliferation, bcl-2 expression and angiogenesis in pituitary adenomas: relationship to tumor behaviour. Br J Cancer 2000;82:1441-5.
11. Zhang HT, Craft P, Scott PA, et al. Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells. J Natl Cancer Inst 1995;87:213-19.
12. Dameron KM, Volpert OV, Tainsky MA, et al. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 1994;265:1582-4.
13. Ravi R, Mookerjee B, Bhujwalla ZM, et al. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. Genes Dev 2000;14:34-44.
14. Perrone G, Vincenzi B, Santini D, et al. Correlation of p53 and bcl-2 expression with vascular endothelial growth factor (VEGF), microvessel density (MVD) and clinico-pathological features in colon cancer. Cancer Lett 2004;208:227-34.
15. Gorgoulis VG, Zacharatos P, Kotsinas A, et al. Altered expression of the cell cycle regulatory molecules pRb, p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs). Mol Med 2000;6:208-37.
16. Takahashi Y, Tucker SL, Kitadai Y, et al. Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer. Arch Surg 1997;132:541-6.
17. Hedley DW, Friedlander ML, Taylor IW, et al. Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry. J Histochem Cytochem 1983;31:1333-5.
18. Hiddemann W, Schumann J, Andreef M, et al. Convention on nomenclature for DNA cytometry. Committee on nomenclature, Society for Analytical Cytology. Cancer Genet Cytogenet 1984;13:181-3.
19. Siitonen SM, Haapasalo HK, Rantala IS, et al. Comparison of different immunohistochemical methods in the assessment of angiogenesis: lack of prognostic value in a group of 77 selected node-negative breast carcinomas. Mod Pathol 1995;8:745-52.
20. Vermeulen PB, Gasparini G, Fox SB, et al. Quantification of angiogenesis in solid human tumours: an international consensus on the methodology and criteria of evaluation. Eur J Cancer 1996;32A:2474-84.
21. Lackner C, Jukic Z, Tsybrovskyy O, et al. Prognostic relevance of tumour-associated macrophages and von Willebrand factor-positive microvessels in colorectal cancer. Virchows Arch 2004;445:160-7.
22. Bosari S, Lee AK, DeLellis RA, et al. Microvessel quantitation and prognosis in invasive breast carcinoma. Hum Pathol 1992;23:755-61.
23. de Jong JS, van Diest PJ, Baak JP. Hot spot microvessel density and the mitotic activity index are strong additional prognostic indicators in invasive breast cancer. Histopathology 2000;36:306-12.
24. Pinto AE, Andre S, Pereira T, et al. Prognostic comparative study of S-phase fraction and Ki-67 index in breast carcinoma. J Clin Pathol 2001;54:543-9.
25. Gasparini G, Boracchi P, Verderio P, et al. Cell kinetics in human breast cancer: comparison between the prognostic value of the cytofluorimetric S-phase fraction and that of the antibodies to Ki-67 and PCNA antigens detected by immunocytochemistry. Int J Cancer 1994;57:822-9.
26. Takahashi Y, Kitadai Y, Bucana CD, et al. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 1995;55:3964-8.
27. Nasif WA, El-Emshaty HM, Tabll A, et al. Immunoreactivity evaluation of mutant p53 gene product with DNA ploidy pattern in colorectal carcinoma. Hepatogastroenterology 2004;51:1001-6.
28. Offerhaus GJ, De Feyter EP, Cornelisse CJ, et al. The relationship of DNA aneuploidy to molecular genetic alterations in colorectal carcinoma. Gastroenterology 1992;102:1612-19.
29. Cross SM, Sanchez CA, Morgan CA, et al. A p53-dependent mouse spindle checkpoint. Science 1995;267:1353-6.
30. Fukasawa K, Choi T, Kuriyama R, et al. Abnormal centrosome amplification in the absence of p53. Science 1996;271:1744-7.
31. Sinicrope FA, Hart J, Michelassi F, et al. Prognostic value of bcl-2 oncoprotein expression in stage II colon carcinoma. Clin Cancer Res 1995;1:103-10.
32. Dey P. Aneuploidy and malignancy: an unsolved equation. J Clin Pathol 2004;57:1245-9.