The BMEI0216 gene of Brucella melitensis is required for internalization in HeLa cells

Microbial Pathogenesis

Volumn 44, Issue 1, 2008, Pages 28-33

  Hernández Castro, Rigoberto ^a   Verdugo Rodríguez, Antonio ^a   Luis Puente, José ^b   Suárez Güemes, Francisco ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

Author keywords

Bacterial pathogenesis; Brucella melitensis; Internalization; Transglycosylase associated protein

Indexed keywords

BACTERIAL PROTEIN; GLYCOSYLTRANSFERASE; KANAMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL INFECTION; BMEI0216 GENE; BRUCELLA MELITENSIS; BRUCELLOSIS; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; INTERNALIZATION; MACROPHAGE; NONHUMAN; OPEN READING FRAME; PHAGOCYTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ANIMALS; BACTERIAL PROTEINS; BRUCELLA MELITENSIS; CELL LINE; GENE ORDER; GENES, BACTERIAL; GENETIC COMPLEMENTATION TEST; HELA CELLS; HUMANS; MACROPHAGES; MICE; MUTATION; TIME FACTORS;

BACTERIA (MICROORGANISMS); BRUCELLA; BRUCELLA MELITENSIS; MURINAE;

EID: 36849048835     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2007.08.008     Document Type: Article

References (28)

1. Corbel M.J. Brucellosis: an overview. Emerg Infect Dis 3 (1997) 213-221
2. Celli J., and Gorvel J.P. Organelle robbery: Brucella interactions with the endoplasmic reticulum. Curr Opin Microbiol 7 (2004) 93-97
3. Boschiroli M.L., Ouahrani-Bettache S., Foulongne V., Michaux-Charachon S., Bourg G., Allerdet-Servent A., et al. The Brucella suis virB operon is induced intracellularly in macrophages. Proc Natl Acad Sci USA 99 (2002) 1544-1549
4. Fretin D., Fauconnier A., Kohler S., Halling S., Leonard S., Nijskens C., et al. The sheathed flagellum of Brucella melitensis is involved in persistence in a murine model of infection. Cell Microbiol 7 (2005) 687-698
5. Kim S., Kurokawa D., Watanabe K., Makino S., Shirahata T., and Watarai M. Brucella abortus nicotinamidase (PncA) contributes to its intracellular replication and infectivity in mice. FEMS Microbiol Lett 234 (2004) 289-295
6. Lavigne J.P., Patey G., Sangari F.J., Bourg G., Ramuz M., O'Callaghan D., et al. Identification of a new virulence factor, BvfA, in Brucella suis. Infect Immun 73 (2005) 5524-5529
7. Loisel-Meyer S., Jiménez-de Bagüés M.P., Bassères E., Dornand J., Köhler S., Liautard J.P., et al. Requirement of norD for Brucella suis virulence in a murine model of in vitro and in vivo infection. Infect Immun 74 (2006) 1973-1976
8. Bandara A., Sriranganathan N., Schurig G., and Boyle S.M. Putative outer membrane autotransporter protein influences survival of Brucella suis in BALB/c mice. Vet Microbiol 109 (2005) 95-104
9. Hornback M.L., and Roop II M.R. The Brucella abortus xthA-1 gene product participates in base excision repair and resistance to oxidative killing but is not required for wild-type virulence in the mouse model. J Bacteriol 188 (2006) 1295-1300
10. Haine V., Dozot M., Dornand J., Letesson J.J., and De Bolle X. NnrA is required for full virulence and regulates several Brucella melitensis denitrification genes. J Bacteriol 188 (2006) 1615-1619
11. Delpino V.M., Marchesini M., Estein S.M., Comerci D.J., Cassataro J., Fossati C.A., et al. A bile salt hydrolase of Brucella abortus contributes to the establishment of a successful infection through the oral route in mice. Infect Immun 75 (2007) 299-305
12. Sola-Landa A., Pizarro-Cerda J., Grillo M.J., Moreno E., Moriyón I., and Blasco J.M. A two-component regulatory system playing critical role in plant pathogens and endosymbionts is present in Brucella abortus and controls cell invasion and virulence. Mol Microbiol 29 (1998) 125-138
13. Castañeda-Roldan E.I., Ouahrani-Bettache S., Saldaña Z., Avelino F., Rendón M.A., Dornand J., et al. Characterization of SP41, a surface protein of Brucella associated with adherence and invasion of host epithelial cells. Cell Microbiol 8 (2006) 1877-1887
14. DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., et al. The genome sequence of the facultative intracellular pathogen Brucella melitensis. Proc Natl Acad Sci USA 99 1 (2002) 443-448
15. Ritting M.G., Kaufmann A., Robins A., Shaw B., Sprenger H., Gemsa D., et al. Smooth and rough lipopolysaccharide phenotypes of Brucella induce different intracellular trafficking and cytokine/chemokine release in human monocytes. J Leukoc Biol 74 (2003) 1-11
16. Castaneda-Roldan E.I., Avelino-Flores F., Dall'Agnol M., Freer E., Cedillo L., Dornand J., et al. Adherence of Brucella to human epithelial cells and macrophages is mediated by sialic acid residues. Cell Microbiol 6 (2004) 435-445
17. Rocha-Gracia R del C., Castaneda-Roldan E.I., Giono-Cerezo S., and Giron J.A. Brucella sp. bind to sialic acid residues on human and animal red blood cells. FEMS Microbiol Lett 213 2 (2002) 219-224
18. Mitchell J.S., and Minnick F.M. Characterization of a two-gene locus from Bartonella bacilliformis associated with the ability to invade human erythrocytes. Infect Immun 63 (1995) 1552-1562
19. Lestrate P., Delrue R., Danese I., Didembourg C., Taminiau B., Mertens P., et al. Identification and characterization of in vivo attenuated mutants of Brucella melitensis. Mol Microbiol 38 (2000) 543-551
20. Kim S., Watarai M., Kondo Y., Erdenebaatar J., Makino S., and Shirahata T. Isolation and characterization of mini-Tn5Km2 insertion mutants of Brucella abortus deficient in internalization and intracellular growth in HeLa cells. Infect Immun 71 (2003) 3020-3027
21. Patey G., Qi Z., Bourg G., Baron C., and O'Callagahn D. Swapping of periplasmic domains between Brucella suis VirB8 and a pSB102 VirB8 homologue allows heterologous complementation. Infect Immun 74 (2006) 4945-4949
22. Zahrl D., Wagner M., Bischof K., Bayer M., Zavecz B., Beranek A., et al. Peptidoglycan degradation by specialized lytic transglycosylases associated with type III and type IV secretion systems. Microbiology 151 (2005) 3455-3467
23. Kokotek W., and Lotz W. Construction of a mobilizable cloning vector for site-directed mutagenesis of gram-negative bacteria: application to Rhizobium leguminosarum. Gene 98 (1991) 7-13
24. Kovach M.E., Elzer P.H., Hill D.S., Robertson G.T., Farris M.A., Roop II R.M., et al. Four new derivatives of the broad-host-range cloning vector pBBR1MCS, carrying different antibiotic-resistance cassettes. Gene 166 (1995) 175-176
25. Simon R., Priefer U., and Pühler A. A broad host range mobilization system for in vivo genetic engineering, transposon mutagenesis in Gram negative bacteria. Bio/Technology 1 (1983) 784-791
26. Sambrook J., Maniatis T., and Fritsch E.F. Molecular cloning: a laboratory manual. 2nd ed. (1989), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
27. Pizarro-Cerda J., Meresse S., Parton R., Van Der Goot G., Sola-Landa A., Lopez-Goñi I., et al. Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes. Infect Immun 66 (1998) 5711-5724
28. Celli J., Chastellier C., Franchini D.-M., Pizarro-Cerda J., Moreno E., and Gorvel J.P. Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum. J Exp Med 198 (2003) 545-556