Conditional disruption of calcineurin B1 in osteoblasts increases bone formation and reduces bone resorption

Journal of Biological Chemistry

Volumn 282, Issue 48, 2007, Pages 35318-35327

  Yeo, Hyeonju ^a   Beck, Lauren H ^a   Thompson, Sunnie R ^b   Farach Carson, Mary C ^c   McDonald, Jay M ^a   Clemens, Thomas L ^a   Zayzafoon, Majd ^a,d  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF DELAWARE   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE FORMATION; BONE RESORPTION; CALCINEURIN B1; CONDITIONAL DISRUPTION;

BONE; COMPUTERIZED TOMOGRAPHY; ENZYME INHIBITION; GENE EXPRESSION;

OSTEOBLASTS;

CALCINEURIN; CALCINEURIN B1; CRE RECOMBINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; IN VITRO STUDY; LOXP SITE; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BONE AND BONES; BONE DEVELOPMENT; BONE RESORPTION; CALCINEURIN; CELL DIFFERENTIATION; CELLS, CULTURED; GENE DELETION; GENE EXPRESSION REGULATION; INTEGRASES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MODELS, BIOLOGICAL; MUSCLE PROTEINS; OSTEOBLASTS; OSTEOCLASTS;

ADENOVIRIDAE; MUS; MUS MUSCULUS;

EID: 36849041442     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702435200     Document Type: Article

References (39)

1. Karsenty, G., and Wagner, E. F. (2002) Dev. Cell 2, 389-406
2. Teitelbaum, S. L. (2000) Science 289, 1504-1508
3. Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S., and Marshak, D. R. (1999) Science 284, 143-147
4. Aubin, J. E. (1998) J. Cell. Biochem. Suppl. 30-31, 73-82
5. Yeo, H., Beck, L. H., McDonald, J. M., and Zayzafoon, M. (2007) Bone (NY) 40, 1502-1516
6. Hogan, P. G., Chen, L., Nardone, J., and Rao, A. (2003) Genes Dev. 17, 2205-2232
7. Klee, C. B., Crouch, T. H., and Krinks, M. H. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 6270-6273
8. Shibasaki, F., Hallin, U., and Uchino, H. (2002) J Biochem. (Tokyo) 131, 1-15
9. Zhu, L. L., Zaidi, S., Moonga, B. S., Troen, B. R., and Sun, L. (2005) Biochem. Biophys. Res. Commun. 326, 131-135
10. Komarova, S. V., Pereverzev, A., Shum, J. W., Sims, S. M., and Dixon, S. J. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 2643-2648
11. Matsuo, K., Galson, D. L., Zhao, C., Peng, L., Laplace, C., Wang, K. Z., Bachler, M. A., Amano, H., Aburatani, H., Ishikawa, H., and Wagner, E. F. (2004) J. Biol. Chem. 279, 26475-26480
12. Hirotani, H., Tuohy, N. A., Woo, J. T., Stern, P. H., and Clipstone, N. A. (2004) J. Biol. Chem. 279, 13984-13992
13. Koga, T., Matsui, Y., Asagiri, M., Kodama, T., de Crombrugghe, B., Nakashima, K., and Takayanagi, H. (2005) Nat. Med. 11, 880-885
14. Sun, L., Blair, H. C., Peng, Y., Zaidi, N., Adebanjo, O. A., Wu, X. B., Wu, X. Y., Iqbal, J., Epstein, S., Abe, E., Moonga, B. S., and Zaidi, M. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 17130-17135
15. Winslow, M. M., Pan, M., Starbuck, M., Gallo, E. M., Deng, L., Karsenty, G., and Crabtree, G. R. (2006) Dev. Cell 10, 771-782
16. Crabtree, G. R., and Olson, E. N. (2002) Cell 109, (Suppl. 1) 67-79
17. Horsley, V., and Pavlath, G. K. (2002) J. Cell Biol. 156, 771-774
18. Zhang, M., Xuan, S., Bouxsein, M. L., von Stechow, D., Akeno, N., Faugere, M. C., Malluche, H., Zhao, G., Rosen, C. J., Efstratiadis, A., and Clemens, T. L. (2002) J. Biol. Chem. 277, 44005-44012
19. Neilson, J. R., Winslow, M. M., Hur, E. M., and Crabtree, G. R. (2004) Immunity 20, 255-266
20. Parfitt, A. M., Drezner, M. K., Glorieux, F. H., Kanis, J. A., Malluche, H., Meunier, P. J., Ott, S. M., and Recker, R. R. (1987) J. Bone Miner. Res. 2, 595-610
21. Zayzafoon, M., Fulzele, K., and McDonald, J. M. (2005) J. Biol. Chem. 280, 7049-7059
22. Liu, X., Bruxvoort, K. J., Zylstra, C. R., Liu, J., Cichowski, R., Faugere, M. C., Bouxsein, M. L., Wan, C., Williams, B. O., and Clemens, T. L. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 2259-2264
23. Zayzafoon, M., Abdulkadir, S. A., and McDonald, J. M. (2004) J. Biol. Chem. 279, 3662-3670
24. Feng, X., Novack, D. V., Faccio, R., Ory, D. S., Aya, K., Boyer, M. I., McHugh, K. P., Ross, F. P., and Teitelbaum, S. L. (2001) J. Clin. Investig. 107, 1137-1144
25. Zayzafoon, M., Gathings, W. E., and McDonald, J. M. (2004) Endocrinology 145, 2421-2432
26. Shin, C. S., Her, S. J., Kim, J. A., Kim, D. H., Kim, S. W., Kim, S. Y., Kim, H. S., Park, K. H., Kim, J. G., Kitazawa, R., Cheng, S. L., and Civitelli, R. (2005) J. Bone Miner. Res. 20, 2200-2212
27. Wagner, E. F. (2002) Ann. Rheum. Dis. 61, Suppl. 2, 40-42
28. McCabe, L. R., Banerjee, C., Kundu, R., Harrison, R. J., Dobner, P. R., Stein, J. L., Lian, J. B., and Stein, G. S. (1996) Endocrinology 137, 4398-4408
29. Klee, C. B., Ren, H., and Wang, X. (1998) J. Biol. Chem. 273, 13367-13370
30. Heit, J. J., Apelqvist, A. A., Gu, X., Winslow, M. M., Neilson, J. R., Crabtree, G. R., and Kim, S. K. (2006) Nature 443, 345-349
31. Chang, C. P., McDill, B. W., Neilson, J. R., Joist, H. E., Epstein, J. A., Crabtree, G. R., and Chen, F. (2004) J. Clin. Investig. 113, 1051-1058
32. Sullivan, K. M., and Rubin, G. M. (2002) Genetics 161, 183-193
33. Kratchmarova, I., Blagoev, B., Haack-Sorensen, M., Kassem, M., and Mann, M. (2005) Science 308, 1472-1477
34. Parsons, S. A., Wilkins, B. J., Bueno, O. F., and Molkentin, J. D. (2003) Mol. Cell. Biol. 23, 4331-4343
35. Zhang, B. W., Zimmer, G., Chen, J., Ladd, D., Li, E., Alt, F. W., Wiederrecht, G., Cryan, J., O'Neill, E. A., Seidman, C. E., Abbas, A. K., and Seidman, J. G. (1996) J. Exp. Med. 183, 413-420
36. Neal, J. W., and Clipstone, N. A. (2003) J. Biol. Chem. 278, 17246-17254
37. Ranger, A. M., Gerstenfeld, L. C., Wang, J., Kon, T., Bae, H., Gravallese, E. M., Glimcher, M. J., and Glimcher, L. H. (2000) J. Exp. Med. 191, 9-22
38. Yang, T. T., Suk, H. Y., Yang, X., Olabisi, O., Yu, R. Y., Durand, J., Jelicks, L. A., Kim, J. Y., Scherer, P. E., Wang, Y., Feng, Y., Rossetti, L., Graef, I. A., Crabtree, G. R., and Chow, C. W. (2006) Mol. Cell. Biol. 26, 7372-7387
39. Kegley, K. M., Gephart, J., Warren, G. L., and Pavlath, G. K. (2001) Dev. Biol. 232, 115-126