Comparative Efficacy of Topical Versus Systemic Teicoplanin in Experimental Model of Wound Infections

Journal of Surgical Research

Volumn 144, Issue 1, 2008, Pages 74-81

  Ghiselli, Roberto ^a   Cirioni, Oscar ^a   Giacometti, Andrea ^a   Scalise, Alessandro ^a   Simonetti, Oriana ^a   Mocchegiani, Federico ^a   Orlando, Fiorenza ^b   Goteri, Gaia ^a   della Vittoria, Agnese ^a   Filosa, Alessandra ^a   Silvestri, Carmela ^a   Offidani, Annamaria ^a   Bertani, Aldo ^a   Scalise, Giorgio ^a   Saba, Vittorio ^a  

^a UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^b INRCA   (Italy)

Author keywords

hydro cellular foam; Staphylococcus aureus; teicoplanin; wounds

Indexed keywords

ALLEVYN; TEICOPLANIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM CULTURE; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG EFFICACY; ENDOTHELIUM CELL; EXPERIMENTAL MODEL; FIBROBLAST; GRAM POSITIVE BACTERIUM; GRANULATION TISSUE; HISTOPATHOLOGY; HOSPITAL INFECTION; HYDROGEL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STAPHYLOCOCCUS AUREUS; SUBCUTANEOUS TISSUE; SURGICAL INFECTION; WOUND INFECTION;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-BACTERIAL AGENTS; DISEASE MODELS, ANIMAL; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; MALE; METHICILLIN RESISTANCE; MICE; MICE, INBRED BALB C; MICROCIRCULATION; SKIN; STAPHYLOCOCCAL INFECTIONS; SURGICAL WOUND INFECTION; TEICOPLANIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 36849036405     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2007.02.051     Document Type: Article

References (29)

1. American Society of Health-System Pharmacists. ASHP therapeutic guidelines on antimicrobial prophylaxis in surgery. Am J Health Syst Pharm 56 (2003) 1839
2. Bratzler D.W., and Houck P.M. Surgical Infection Prevention Guidelines Writers Workgroup. Antimicrobial prophylaxis for surgery: An advisory statement from the National Surgical Infection Prevention Project. Clin Infect Dis 38 (2004) 1706
3. Burke J.P. Infection control-a problem for patient safety. N Engl J Med 348 (2003) 651
4. Kirkland K.B., Briggs J.P., Trivette S.L., et al. The impact of surgical site infections in the 1990s: Attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol 20 (1999) 725
5. Horan T.C., Gaynes R.P., Martone W.J., et al. CDC definitions of nosocomial surgical site infections, 1992: A modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol 13 (1992) 606
6. Jawhara S., and Nordon S. In vivo imaging of bioluminescent Escherichia coli in a cutaneous wound infection model for evaluation of an antibiotic therapy. Antimicrob Agents Chemother 48 (2004) 3436
7. Guay D.R. Treatment of bacterial skin and skin structure infections. Expert Opin Pharmacother 4 (2003) 1259
8. National Nosocomial Infections Surveillance (NNIS) report. Data summary from October 1986-April 1996: A report from the National Nosocomial Infections Surveillance (NNIS) System. Am J Infect Control 24 (1996) 380
9. Cormican M.G., and Jones R.N. Emerging resistance to antimicrobial agents in gram-positive bacteria. Enterococci, Staphylococci, and nonpneumococcal streptococci. Drugs 51 (1996) S6
10. Fung H.B., Chang J.Y., and Kuczyski S.A. Practical guide to the treatment of complicated skin and soft tissue infections. Drugs 63 (2003) 1459
11. Raad I., Alrahwan A., and Rolston K. Staphylococcus epidermidis: Emerging resistance and need for alternative agents. Clin Infect Dis 26 (1998) 1182
12. Schimdt F.R. The challenge of multidrug resistance: Actual strategies in the development of novel antibacterials. Appl Microbiol Biotechnol 63 (2004) 335
13. Howell-Jones R.S., Wilson M.J., Hill K.E., et al. A review of the microbiology, antibiotic usage and resistance in chronic skin wounds. J Antimicrob Chemother 55 (2005) 143
14. Bjellerup M. Novel method for training skin flap surgery: Polyurethane foam dressing used as a skin equivalent. Dermatol Surg 31 (2005) 1107
15. Vaingankar N.V., Sylaidis P., Eagling V., et al. Comparison of hydrocellular foam and calcium alginate in the healing and comfort of split-thickness skin-graft donor sites. J Wound Care 10 (2001) 289
16. Williams C. Allevyn. Br J Nurs 4 (1995) 107
17. Dinar S. A new material for the standard burn model: Allevyn adhesive. Plas Reconstr Surg 117 (2006) 717
18. Crovetti G., Martinelli G., Issi M., et al. Platelet gel for healing cutaneous chronic wounds. Transfus Apher Sci 30 (2004) 145
19. Craig W. Relevance of animal models for clinical treatment. Eur J Clin Microbiol Infect Dis 12 (1993) S55
20. Kugelberg E., Norstrom T., Petersen T.K., et al. Establishment of a superficial skin infection model in mice by using Staphylococcus aureu and Streptococcus pyogenes. Antimicrob Agents Chemother 49 (2005) 3435
21. Akiyama H., Kanzaki H., Abe Y., et al. Staphylococcus aureus infection on experimental croton oil-inflamed skin in mice. J Dermatol Sci 8 (1994) 1
22. Bunce C., Wheeler L., Reed G., et al. Murine model of cutaneous infection with gram-positive cocci. Infect Immun 60 (1992) 2636
23. Pace J.L., and Yang G. Glycopeptides: Update on an old successful antibiotic class. Biochem Pharmacol 71 (2006) 968
24. Byrne A.M., Bouchier-Hayes D.J., and Harmey J.H. Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF). J Cell Mol Med 9 (2005) 777
25. Carmeliet P. VEGF as a key mediator of angiogenesis in cancer. Oncology 69 (2005) S4
26. Cianfarani F., Tommasi R., Failla C.M., et al. Granulocyte/macrophage colony-stimulating factor treatment of human chronic ulcers promotes angiogenesis associated with de novo vascular endothelial growth factor transcription in the ulcer bed. Br J Dermatol 154 (2006) 34
27. Ferrara N. VEGF as a therapeutic target in cancer. Oncology 69 (2005) S11
28. Robson M.C. Wound infection. A failure of wound healing caused by an imbalance of bacteria. Surg Clin N Am 77 (1997) 637
29. Khodaparast O., Dana M.M., Jonathon M., et al. A. Effect of a transpositional muscle flap on VEGF mRNA expression in a canine fracture model. Plast Reconstr Surg 112 (2003) 171