-
1
-
-
0034946112
-
Expression of the peptide antibiotics human beta defensin 1 and human beta defensin 2 in normal human skin
-
Ali RS, Falconer A, Ikram M, Bissett CE, Cerio R, Quinn AG (2001) Expression of the peptide antibiotics human beta defensin 1 and human beta defensin 2 in normal human skin. J Invest Dermatol 117:106-111
-
(2001)
J Invest Dermatol
, vol.117
, pp. 106-111
-
-
Ali, R.S.1
Falconer, A.2
Ikram, M.3
Bissett, C.E.4
Cerio, R.5
Quinn, A.G.6
-
2
-
-
0033850685
-
Friulimicins: Novel lipopetide antibiotics with peptidoglycan synthesis inhibiting activity from Actinoplanes friulensis sp. Nov. I. Taxonomic studies of the producing microorganism and fermentation
-
Aretz W, Meiwes J, Seibert G, Vobis G, Wink J (2000) Friulimicins: novel lipopetide antibiotics with peptidoglycan synthesis inhibiting activity from Actinoplanes friulensis sp. Nov. I. Taxonomic studies of the producing microorganism and fermentation. J Antibiot 53:807-815
-
(2000)
J Antibiot
, vol.53
, pp. 807-815
-
-
Aretz, W.1
Meiwes, J.2
Seibert, G.3
Vobis, G.4
Wink, J.5
-
4
-
-
0033870682
-
Assessment of the susceptibility of Streptococcus pneumoniae to cefaclor and loracarbef in 13 countries
-
Bandak, SI, Tumak MR, Allen BS, Bolzon LD, Preston DA (2000) Assessment of the susceptibility of Streptococcus pneumoniae to cefaclor and loracarbef in 13 countries. J Chemother 12:299-305
-
(2000)
J Chemother
, vol.12
, pp. 299-305
-
-
Bandak, S.I.1
Tumak, M.R.2
Allen, B.S.3
Bolzon, L.D.4
Preston, D.A.5
-
5
-
-
0035188391
-
Structure determination of human and murine beta defensins reveal structural conservation in the absence of significant sequence similarity
-
Bauer F, Schweimer K, Kluver E, Conejo-Garcia I, Forssmann W, Rosch P, Adermann K, Sticht H (2001) Structure determination of human and murine beta defensins reveal structural conservation in the absence of significant sequence similarity. Protein Sci 10:2470-2479
-
(2001)
Protein Sci
, vol.10
, pp. 2470-2479
-
-
Bauer, F.1
Schweimer, K.2
Kluver, E.3
Conejo-Garcia, I.4
Forssmann, W.5
Rosch, P.6
Adermann, K.7
Sticht, H.8
-
6
-
-
0033847734
-
The millennium bugs-the need for and development of new antibacterials
-
Bax R, Mullan N, Verhoef J (2000) The millennium bugs-the need for and development of new antibacterials. Int J Antimicrob Agents 16:51-59
-
(2000)
Int J Antimicrob Agents
, vol.16
, pp. 51-59
-
-
Bax, R.1
Mullan, N.2
Verhoef, J.3
-
7
-
-
0035979758
-
Solid state NMR investigations of interaction contributions that determine the alignment of helical polypeptides in biological membranes
-
Bechinger B (2001) Solid state NMR investigations of interaction contributions that determine the alignment of helical polypeptides in biological membranes. FEBS Lett 504:161-165
-
(2001)
FEBS Lett
, vol.504
, pp. 161-165
-
-
Bechinger, B.1
-
8
-
-
0000251837
-
Synthetic combinatorial libraries: An emerging approach toward the identification of novel antibiotics
-
Lohner K (ed). Horizon, Wymondham, Norfolk, UK
-
Blondelle SE (2001) Synthetic combinatorial libraries: an emerging approach toward the identification of novel antibiotics. In: Lohner K (ed) Development of novel antimicrobial agents: emerging strategies. Horizon, Wymondham, Norfolk, UK, pp 199-216
-
(2001)
Development of Novel Antimicrobial Agents: Emerging Strategies
, pp. 199-216
-
-
Blondelle, S.E.1
-
9
-
-
0033863173
-
Combinatorial libraries: A tool to design antimicrobial and antifungal peptides analogues having lytic specificities for structure-activity relationship studies
-
Blondelle SE, Lohner K (2000) Combinatorial libraries: a tool to design antimicrobial and antifungal peptides analogues having lytic specificities for structure-activity relationship studies. Biopolymers 55:74-87
-
(2000)
Biopolymers
, vol.55
, pp. 74-87
-
-
Blondelle, S.E.1
Lohner, K.2
-
10
-
-
0030049034
-
Rapid identification of compounds having enhanced microbial activity using conformationally defined combinatorial libraries
-
Blondelle SE, Takahashi E, Houghten RA, Perez-Paya E (1996) Rapid identification of compounds having enhanced microbial activity using conformationally defined combinatorial libraries. Biochem J 313:141-147
-
(1996)
Biochem J
, vol.313
, pp. 141-147
-
-
Blondelle, S.E.1
Takahashi, E.2
Houghten, R.A.3
Perez-Paya, E.4
-
11
-
-
0025363404
-
A54145, a new lipopeptide antibiotic complex: Factor control through precursor-directed biosynthesis
-
Boeck LD, Wetzel RW (1990) A54145, a new lipopeptide antibiotic complex: factor control through precursor-directed biosynthesis. J Antibiotics 43:607-615
-
(1990)
J Antibiotics
, vol.43
, pp. 607-615
-
-
Boeck, L.D.1
Wetzel, R.W.2
-
12
-
-
0025368316
-
A54145, a new lipopeptide antibiotic complex: Discovery, taxonomy, fermentation and HPLC
-
Boeck LD, Papiska HR, Wetzel RW, Mynderse JS, Fukuda DS, Mertz FP, Berry DM (1990) A54145, a new lipopeptide antibiotic complex: discovery, taxonomy, fermentation and HPLC. J Antibiotics 43:587-593
-
(1990)
J Antibiotics
, vol.43
, pp. 587-593
-
-
Boeck, L.D.1
Papiska, H.R.2
Wetzel, R.W.3
Mynderse, J.S.4
Fukuda, D.S.5
Mertz, F.P.6
Berry, D.M.7
-
13
-
-
0035019615
-
In vivo efficacy of the new ketolide telithromycin (HMR 3647) in murine infection models
-
Bonnefoy A, Guitton M, Delachaume C, Le Priol P, Girard AM (2001) In vivo efficacy of the new ketolide telithromycin (HMR 3647) in murine infection models. Antimicrob Agents Chemother 45:1688-1692
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 1688-1692
-
-
Bonnefoy, A.1
Guitton, M.2
Delachaume, C.3
Le Priol, P.4
Girard, A.M.5
-
14
-
-
0035110794
-
Inhibition of quorum sensing by a Pseudomonas aeruginosa dksa homologue
-
Branny P, Pearson JP, Everett CP, Köhler T, Iglewski BH, van Delden C (2001) Inhibition of quorum sensing by a Pseudomonas aeruginosa dksA homologue. J Bacteriol 183:1531-1539
-
(2001)
J Bacteriol
, vol.183
, pp. 1531-1539
-
-
Branny, P.1
Pearson, J.P.2
Everett, C.P.3
Köhler, T.4
Iglewski, B.H.5
Van Delden, C.6
-
15
-
-
0033579207
-
Use of the cell wall precursor lipid II by pore forming peptide antibiotic
-
Breukink E, Wiedemann I, Van Kraaij C, Kuipers OP, Sahl HG, De Kruijff (1999) Use of the cell wall precursor lipid II by pore forming peptide antibiotic. Science 286:2361-2364
-
(1999)
Science
, vol.286
, pp. 2361-2364
-
-
Breukink, E.1
Wiedemann, I.2
Van Kraaij, C.3
Kuipers, O.P.4
Sahl, H.G.5
De Kruijff6
-
16
-
-
0029831102
-
Quinupristin-Dalfopristin
-
Bryson HM, Spencer CM (1996) Quinupristin-Dalfopristin. Drugs 52:406-415
-
(1996)
Drugs
, vol.52
, pp. 406-415
-
-
Bryson, H.M.1
Spencer, C.M.2
-
17
-
-
0033485280
-
The parallel and convergent universes of polyketide synthases and non-ribosomal peptide synthases
-
Cane DE, Walsh CT (1999) The parallel and convergent universes of polyketide synthases and non-ribosomal peptide synthases. Chem Biol 6:R319-R325
-
(1999)
Chem Biol
, vol.6
-
-
Cane, D.E.1
Walsh, C.T.2
-
18
-
-
0034075717
-
Studies of the novel ketolide ABT-773: Transport, binding to ribosomes and inhibition of protein synthesis in Streptococcus pneumoniae
-
Capobianco JO, Cao Z, Shortridge VD, Ma Z, Flamm RK, Zhong P (2000) Studies of the novel ketolide ABT-773: transport, binding to ribosomes and inhibition of protein synthesis in Streptococcus pneumoniae. Antimicrob Agents Chemother 44:1562-1567
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 1562-1567
-
-
Capobianco, J.O.1
Cao, Z.2
Shortridge, V.D.3
Ma, Z.4
Flamm, R.K.5
Zhong, P.6
-
19
-
-
0030921538
-
Emergent antibiotic resistance: Health risks and economic impact
-
Cassell GH (1997) Emergent antibiotic resistance: health risks and economic impact. FEMS Immunol Med Microbiol 18:271-274
-
(1997)
FEMS Immunol Med Microbiol
, vol.18
, pp. 271-274
-
-
Cassell, G.H.1
-
21
-
-
0035993441
-
Rational identification of new antibacterial drug targets that are essential for viability using a genomic based approach
-
Chalker AF, Lunsford RD (2002) Rational identification of new antibacterial drug targets that are essential for viability using a genomic based approach. Pharmacol Ther 95:1-20
-
(2002)
Pharmacol Ther
, vol.95
, pp. 1-20
-
-
Chalker, A.F.1
Lunsford, R.D.2
-
22
-
-
0031037207
-
The search for antimicrobial agents effective against bacteria resistant to multiple antibiotics
-
Chopra I, Hodgson J, Metcalf B, Poste G (1997) The search for antimicrobial agents effective against bacteria resistant to multiple antibiotics. Antimicrob Agents Chemother 41:497-503
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 497-503
-
-
Chopra, I.1
Hodgson, J.2
Metcalf, B.3
Poste, G.4
-
23
-
-
0029956752
-
Vancomycin resistant enterococci from nosocomial, community and animal sources in the United States
-
Coque TM, Tomayko JF, Ricke SC, Okhuysen PC (1996) Vancomycin resistant enterococci from nosocomial, community and animal sources in the United States. Antimicrob Agents Chemother 40:2605-2609
-
(1996)
Antimicrob Agents Chemother
, vol.40
, pp. 2605-2609
-
-
Coque, T.M.1
Tomayko, J.F.2
Ricke, S.C.3
Okhuysen, P.C.4
-
24
-
-
0029931116
-
Emerging resistance to antimicrobial agents in Gram-positive bacteria
-
Cormican MG, Jones RN (1996) Emerging resistance to antimicrobial agents in Gram-positive bacteria. Drugs 51 Suppl 1:1-16
-
(1996)
Drugs
, vol.51
, Issue.1 SUPPL.
, pp. 1-16
-
-
Cormican, M.G.1
Jones, R.N.2
-
26
-
-
0025339421
-
A54145, a new lipopetide antibiotic complex: Microbiological evaluation
-
Counter FT, Allen NE, Fukuda DS, Hobbs JN, Ott J, Ensminger PW, Mynderse JS, Preston DA, Wu, CYE (1990) A54145, a new lipopetide antibiotic complex: microbiological evaluation. J Antibiot 43:616-622
-
(1990)
J Antibiot
, vol.43
, pp. 616-622
-
-
Counter, F.T.1
Allen, N.E.2
Fukuda, D.S.3
Hobbs, J.N.4
Ott, J.5
Ensminger, P.W.6
Mynderse, J.S.7
Preston, D.A.8
Wu, C.Y.E.9
-
27
-
-
0034913085
-
DNA-chips: A new tool for genetic analysis and diagnostics
-
Cuzin M (2001) DNA-chips: a new tool for genetic analysis and diagnostics. Transfus Clin Biol 8:291-296
-
(2001)
Transfus Clin Biol
, vol.8
, pp. 291-296
-
-
Cuzin, M.1
-
28
-
-
0035065966
-
Biosynthesis of hybrid peptide-polyketide natural products
-
Du L, Shen B (2001) Biosynthesis of hybrid peptide-polyketide natural products. Curr Opin Drug Discov Dev 4:215-228
-
(2001)
Curr Opin Drug Discov Dev
, vol.4
, pp. 215-228
-
-
Du, L.1
Shen, B.2
-
29
-
-
0034796211
-
Hybrid peptide-polyketide natural products: Biosynthesis and prospects towards engineering novel molecules
-
Du L, Sanchez C, Shen B (2001) Hybrid peptide-polyketide natural products: biosynthesis and prospects towards engineering novel molecules. Metab Eng 3:78-95
-
(2001)
Metab Eng
, vol.3
, pp. 78-95
-
-
Du, L.1
Sanchez, C.2
Shen, B.3
-
30
-
-
0027367760
-
Lantibiotika, eine Klasse ribosomal synthetisierter Peptid-Antibiotika
-
Entian KD, Klein C (1993) Lantibiotika, eine Klasse ribosomal synthetisierter Peptid-Antibiotika. Naturwissenschaften 80:454-460
-
(1993)
Naturwissenschaften
, vol.80
, pp. 454-460
-
-
Entian, K.D.1
Klein, C.2
-
31
-
-
0034762933
-
Activity of the ketolide antibacterial telithromycin against typical community-acquired respiratory pathogens
-
Felmingham D, Zhanel G, Hoban D (2001) Activity of the ketolide antibacterial telithromycin against typical community-acquired respiratory pathogens. J Antimicrob Chemother 48:33-42
-
(2001)
J Antimicrob Chemother
, vol.48
, pp. 33-42
-
-
Felmingham, D.1
Zhanel, G.2
Hoban, D.3
-
32
-
-
0035954729
-
Antibacterial agents based on the cyclic D,L-a-peptide architecture
-
Fernandez-Lopez S, Kim HS, Choi EC, Delgado M, Granja JR, Khasanov A, Kraehenbuehl A, Long G, Weinberger DA, Wilcoxen KM, Ghadiri R (2001) Antibacterial agents based on the cyclic D,L-a-peptide architecture. Nature 412:452-455
-
(2001)
Nature
, vol.412
, pp. 452-455
-
-
Fernandez-Lopez, S.1
Kim, H.S.2
Choi, E.C.3
Delgado, M.4
Granja, J.R.5
Khasanov, A.6
Kraehenbuehl, A.7
Long, G.8
Weinberger, D.A.9
Wilcoxen, K.M.10
Ghadiri, R.11
-
33
-
-
0030004654
-
Antibacterial activity of Quinupristin/Dalfopristin
-
Finch RG (1996) Antibacterial activity of Quinupristin/Dalfopristin. Drugs 51 [Suppl 1]:31-37
-
(1996)
Drugs
, vol.51
, Issue.1 SUPPL.
, pp. 31-37
-
-
Finch, R.G.1
-
34
-
-
0035734752
-
Antibiotic synthesis: From natural to unnatural products
-
Floss HG (2001) Antibiotic synthesis: from natural to unnatural products. J Ind Microbiol Biotechnol 27:183-194
-
(2001)
J Ind Microbiol Biotechnol
, vol.27
, pp. 183-194
-
-
Floss, H.G.1
-
35
-
-
0029802138
-
Antimicrobial drug resistance
-
Gold HS, Moellering RC (1996) Antimicrobial drug resistance. Drug Therapy 335:1445-1453
-
(1996)
Drug Therapy
, vol.335
, pp. 1445-1453
-
-
Gold, H.S.1
Moellering, R.C.2
-
36
-
-
0034581968
-
High throughput and virtual screening: Core lead discovery technologies move towards integration
-
Good AC, Krystek SR, Mason JS (2000) High throughput and virtual screening: core lead discovery technologies move towards integration: Drug Discov Today 5 [12 Suppl 1]:S61-S69
-
(2000)
Drug Discov Today
, vol.5
, Issue.12 SUPPL. 1
-
-
Good, A.C.1
Krystek, S.R.2
Mason, J.S.3
-
37
-
-
0003401938
-
Origins and evolution of antibiotic and multiple antibiotic resistance in bacteria
-
Lohner K (ed). Horizon, Wymondham, Norfolk, UK
-
Hall RM, Collis CM (2001) Origins and evolution of antibiotic and multiple antibiotic resistance in bacteria. In: Lohner K (ed) Development of novel antimicrobial agents: emerging strategies. Horizon, Wymondham, Norfolk, UK, pp 17-30
-
(2001)
Development of Novel Antimicrobial Agents: Emerging Strategies
, pp. 17-30
-
-
Hall, R.M.1
Collis, C.M.2
-
38
-
-
0035984978
-
Clinical development of cationic antimicrobial peptides: From natural to novel antibiotics
-
Hancock REW, Patrzykat A (2002) Clinical development of cationic antimicrobial peptides: from natural to novel antibiotics. Curr Drug Targets Infect Disord 2:79-83
-
(2002)
Curr Drug Targets Infect Disord
, vol.2
, pp. 79-83
-
-
Hancock, R.E.W.1
Patrzykat, A.2
-
39
-
-
0037050278
-
Role of membranes in the activities of antimicrobial cationic peptides
-
Hancock REW, Rozek A (2002) Role of membranes in the activities of antimicrobial cationic peptides. FEMS Microbiol Lett 10:143-149
-
(2002)
FEMS Microbiol Lett
, vol.10
, pp. 143-149
-
-
Hancock, R.E.W.1
Rozek, A.2
-
40
-
-
0034255255
-
The role of antimicrobial peptides in animal defences
-
Hancock REW, Scott MG (2000) The role of antimicrobial peptides in animal defences. Proc Natl Acad Sci USA 97:8856-8861
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8856-8861
-
-
Hancock, R.E.W.1
Scott, M.G.2
-
41
-
-
0036259508
-
Genomics in anti-infective drug discovery-getting to an endgame
-
Haney SA, Alksne LE, Dunman PM, Murphy E, Projan SJ (2002) Genomics in anti-infective drug discovery-getting to an endgame. Curr Pharm Des 8:1099-1118
-
(2002)
Curr Pharm des
, vol.8
, pp. 1099-1118
-
-
Haney, S.A.1
Alksne, L.E.2
Dunman, P.M.3
Murphy, E.4
Projan, S.J.5
-
42
-
-
0003704961
-
-
Statement before the United States House of Representatives. World Health Organisation, Geneva, Switzerland
-
Heymann DL (2000) The urgency of a massive effort against infectious diseases. Statement before the United States House of Representatives. World Health Organisation, Geneva, Switzerland
-
(2000)
The Urgency of a Massive Effort Against Infectious Diseases
-
-
Heymann, D.L.1
-
43
-
-
0032577607
-
The emergence of Staphylococcus aureus with reduced susceptibility to vancomycin in Japan
-
Hiramatsu K (1998) The emergence of Staphylococcus aureus with reduced susceptibility to vancomycin in Japan. Am J Med 104:7S-10S
-
(1998)
Am J Med
, vol.104
-
-
Hiramatsu, K.1
-
44
-
-
0030841073
-
Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility
-
Hiramatsu K, Hanaki K, Ino T, Yabuta K, Oguri T, Tenover FC (1997) Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. J Antimicrob Chemother 40:135-146
-
(1997)
J Antimicrob Chemother
, vol.40
, pp. 135-146
-
-
Hiramatsu, K.1
Hanaki, K.2
Ino, T.3
Yabuta, K.4
Oguri, T.5
Tenover, F.C.6
-
45
-
-
0035153489
-
Streptococcus pneumoniae: New tools for an old pathogen
-
Hollingshead SK, Briles DE (2001) Streptococcus pneumoniae: new tools for an old pathogen. Curr Opin Microbiol 4:71-77
-
(2001)
Curr Opin Microbiol
, vol.4
, pp. 71-77
-
-
Hollingshead, S.K.1
Briles, D.E.2
-
46
-
-
0036380705
-
New methods in drug research
-
Höltje HD, Stoll F, Ghosh R, Stahl G, Höltje M (2002) New methods in drug research. Pharm Ind 64:838-843
-
(2002)
Pharm Ind
, vol.64
, pp. 838-843
-
-
Höltje, H.D.1
Stoll, F.2
Ghosh, R.3
Stahl, G.4
Höltje, M.5
-
47
-
-
0028811381
-
Polyketide synthase gene manipulation : A structure-function approach in engineering novel antibiotics
-
Hutchinson CR, Fujii I (1995) Polyketide synthase gene manipulation : a structure-function approach in engineering novel antibiotics. Annu Rev Microbiol 49:201
-
(1995)
Annu Rev Microbiol
, vol.49
, pp. 201
-
-
Hutchinson, C.R.1
Fujii, I.2
-
48
-
-
0031847502
-
Antibacterial activity of synthetic dermaseptins against growing and non-growing E. coli cultures
-
Jouenne T, Mor A, Bonato H, Junter GA (1998) Antibacterial activity of synthetic dermaseptins against growing and non-growing E. coli cultures. J Antimicrob Chemother 42:87-90
-
(1998)
J Antimicrob Chemother
, vol.42
, pp. 87-90
-
-
Jouenne, T.1
Mor, A.2
Bonato, H.3
Junter, G.A.4
-
49
-
-
0017684889
-
Fatty acids of the genus Bacillus: An example of branched chain preference
-
Kaneda T (1977) Fatty acids of the genus Bacillus: an example of branched chain preference. Bacteriol Rev 41:391-418
-
(1977)
Bacteriol Rev
, vol.41
, pp. 391-418
-
-
Kaneda, T.1
-
50
-
-
0027382486
-
Polyketide synthesis: Prospects for hybrid antibiotics
-
Katz L, Donadio S (1993) Polyketide synthesis: prospects for hybrid antibiotics. Annu Rev Microbiol 47:875-912
-
(1993)
Annu Rev Microbiol
, vol.47
, pp. 875-912
-
-
Katz, L.1
Donadio, S.2
-
51
-
-
0029086657
-
Linking peptide and polyketide biosynthesis
-
Kleinkauf H, von Döhren H (1995) Linking peptide and polyketide biosynthesis. J Antibiot 48:563-567
-
(1995)
J Antibiot
, vol.48
, pp. 563-567
-
-
Kleinkauf, H.1
Von Döhren, H.2
-
52
-
-
0035385153
-
MALDI-Tof mass spectrometry of bacteria
-
Lay JO (2001) MALDI-TOF mass spectrometry of bacteria. Mass Spectrom Rev 20:172-194
-
(2001)
Mass Spectrom Rev
, vol.20
, pp. 172-194
-
-
Lay, J.O.1
-
53
-
-
0029825534
-
Epidemiology and control of multiresistant enterococci
-
Leclercq JV (1996) Epidemiology and control of multiresistant enterococci. Drugs 52:47-49
-
(1996)
Drugs
, vol.52
, pp. 47-49
-
-
Leclercq, J.V.1
-
54
-
-
0034752380
-
Overcoming antimicrobial resistance: Profile of a new ketolide antibacterial, telithromycin
-
Leclercq R (2001) Overcoming antimicrobial resistance: profile of a new ketolide antibacterial, telithromycin. J Antimicrob Chemother 48:9-23
-
(2001)
J Antimicrob Chemother
, vol.48
, pp. 9-23
-
-
Leclercq, R.1
-
55
-
-
0036135697
-
Cathelicidins: A family of endogenous antimicrobial peptides
-
Lehrer RI, Ganz T (2002) Cathelicidins: a family of endogenous antimicrobial peptides. Curr Opin Hematol 9:18-22
-
(2002)
Curr Opin Hematol
, vol.9
, pp. 18-22
-
-
Lehrer, R.I.1
Ganz, T.2
-
56
-
-
0003814337
-
Synthesis and metabolism of drugs by means of enzyme catalysed reactions
-
Leuenberger HGW, Matzinger PK, Wirz B (1999) Synthesis and metabolism of drugs by means of enzyme catalysed reactions. Chimia 53:536-540
-
(1999)
Chimia
, vol.53
, pp. 536-540
-
-
Leuenberger, H.G.W.1
Matzinger, P.K.2
Wirz, B.3
-
57
-
-
0002336563
-
Are we on the threshold of the post-antibiotic era?
-
Lohner K (ed). Horizon, Wymondham, Norfolk, UK
-
Lohner K, Staudegger E (2001) Are we on the threshold of the post-antibiotic era? In: Lohner K (ed) Development of novel antimicrobial agents: emerging strategies. Horizon, Wymondham, Norfolk, UK, pp 1-16
-
(2001)
Development of Novel Antimicrobial Agents: Emerging Strategies
, pp. 1-16
-
-
Lohner, K.1
Staudegger, E.2
-
59
-
-
9444278428
-
Modular peptide synthases involved in nonribosomal peptide synthesis
-
Marahiel MA, Stachelhaus T, Mootz HD (1997) Modular peptide synthases involved in nonribosomal peptide synthesis. Chem Rev 97:2651-2673
-
(1997)
Chem Rev
, vol.97
, pp. 2651-2673
-
-
Marahiel, Ma.1
Stachelhaus, T.2
Mootz, H.D.3
-
60
-
-
0031873963
-
New aspects of genes and enzymes for β-lactam antibiotic synthesis
-
Martin JF (1998) New aspects of genes and enzymes for β-lactam antibiotic synthesis. Appl Microbiol Biotechnol 50:1-15
-
(1998)
Appl Microbiol Biotechnol
, vol.50
, pp. 1-15
-
-
Martin, J.F.1
-
61
-
-
1642454438
-
Genetic engineering of novel macrolide antibiotics
-
Lohner K (ed). Horizon, Wymondham, Norfolk, UK
-
McDaniel R, Katz L (2001) Genetic engineering of novel macrolide antibiotics. In: Lohner K (ed) Development of novel antimicrobial agents: emerging strategies. Horizon, Wymondham, Norfolk, UK, pp 45-60
-
(2001)
Development of Novel Antimicrobial Agents: Emerging Strategies
, pp. 45-60
-
-
McDaniel, R.1
Katz, L.2
-
63
-
-
0033814969
-
Peptide-based antibiotics: A potential answer to raging antimicrobial resistance
-
Mor A (2000) Peptide-based antibiotics: a potential answer to raging antimicrobial resistance. Drug Dev Res 50:440-447
-
(2000)
Drug Dev Res
, vol.50
, pp. 440-447
-
-
Mor, A.1
-
64
-
-
0027988532
-
The venebrate peptide antibiotics dermaseptins have overlapping structural features but target specific organisms
-
Mor A, Hani K, Nicolas P (1994) The venebrate peptide antibiotics dermaseptins have overlapping structural features but target specific organisms. J Biol Chem 269:31635-31641
-
(1994)
J Biol Chem
, vol.269
, pp. 31635-31641
-
-
Mor, A.1
Hani, K.2
Nicolas, P.3
-
65
-
-
0035873909
-
Design of Gram-negative selective antimicrobial peptides
-
Muhle SA, Tam JP (2001) Design of Gram-negative selective antimicrobial peptides. Biochemistry 40:5777-5785
-
(2001)
Biochemistry
, vol.40
, pp. 5777-5785
-
-
Muhle, S.A.1
Tam, J.P.2
-
66
-
-
0036007181
-
Mechanismen der Antibiotikaresistenz
-
Muhlemann K (2002) Mechanismen der Antibiotikaresistenz. Ther Umschau 59:5-10
-
(2002)
Ther Umschau
, vol.59
, pp. 5-10
-
-
Muhlemann, K.1
-
69
-
-
0036046826
-
Bacterial proteomic and vaccine development
-
Nilsson CL (2002) Bacterial proteomic and vaccine development. Am J Pharmacogenomics 2:59-65
-
(2002)
Am J Pharmacogenomics
, vol.2
, pp. 59-65
-
-
Nilsson, C.L.1
-
70
-
-
0030974953
-
Ribosomally synthesized antimicrobial peptides: Their function, structure, biogenesis, and mechanism of action
-
Nissen-Meyer J, Nes IF (1997) Ribosomally synthesized antimicrobial peptides: their function, structure, biogenesis, and mechanism of action. Arch Microbiol 167:67-77
-
(1997)
Arch Microbiol
, vol.167
, pp. 67-77
-
-
Nissen-Meyer, J.1
Nes, I.F.2
-
71
-
-
0031942622
-
Susceptibilities of penicillin and erythromycin susceptible and resistant Pneumococci to HMR 3647 (RU 66647), a new ketolide, compared with susceptibilities to 17 other agents
-
Pankuch GA, Visalli MA, Jacobs MR, Applebaum PC (1998) Susceptibilities of penicillin and erythromycin susceptible and resistant Pneumococci to HMR 3647 (RU 66647), a new ketolide, compared with susceptibilities to 17 other agents. Antimicrob Agents Chemother 42:624-630
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 624-630
-
-
Pankuch, G.A.1
Visalli, M.A.2
Jacobs, M.R.3
Applebaum, P.C.4
-
72
-
-
0036606204
-
ConsDock: A new program for the consensus analysis of protein-ligand interaction
-
Paul N, Rognan D (2002) ConsDock: a new program for the consensus analysis of protein-ligand interaction. Proteins Struct Funct Genet 47:521-533
-
(2002)
Proteins Struct Funct Genet
, vol.47
, pp. 521-533
-
-
Paul, N.1
Rognan, D.2
-
73
-
-
0034854845
-
Detection of natural peptide antibiotics in human nasolacrimal ducts
-
Paulsen FP, Pufe T, Schaudig U, Held-Feindt J, Lehmann J, Schroder JM, Tillmann BN (2001) Detection of natural peptide antibiotics in human nasolacrimal ducts. Invest Ophthalmol Vis Sci 42:2157-2163
-
(2001)
Invest Ophthalmol Vis Sci
, vol.42
, pp. 2157-2163
-
-
Paulsen, F.P.1
Pufe, T.2
Schaudig, U.3
Held-Feindt, J.4
Lehmann, J.5
Schroder, J.M.6
Tillmann, B.N.7
-
74
-
-
0030004653
-
Streptogramins
-
Pechère JC (1996) Streptogramins. Drugs 51 [Suppl 1]:13-19
-
(1996)
Drugs
, vol.51
, Issue.1 SUPPL.
, pp. 13-19
-
-
Pechère, J.C.1
-
75
-
-
0035102454
-
Biosynthesis of polyketides in heterologous hosts
-
Pfeifer BA, Khosla C (2001) Biosynthesis of polyketides in heterologous hosts. Microbiol Mol Biol Rev 3:106-118
-
(2001)
Microbiol Mol Biol Rev
, vol.3
, pp. 106-118
-
-
Pfeifer, B.A.1
Khosla, C.2
-
76
-
-
0036126821
-
Impact of integrons and transposons on the evolution of resistance and virulence
-
Hacker J, Kaper JB (eds). Springer, Berlin Heidelberg New York
-
Rowe-Magnus DA, Davies J, Mazel D (2002a) Impact of integrons and transposons on the evolution of resistance and virulence. In: Hacker J, Kaper JB (eds) Pathogenicity islands and the evolution of pathogenic microbes. Springer, Berlin Heidelberg New York, pp 167-188
-
(2002)
Pathogenicity Islands and the Evolution of Pathogenic Microbes
, pp. 167-188
-
-
Rowe-Magnus, D.A.1
Davies, J.2
Mazel, D.3
-
77
-
-
0036126821
-
Impact of integrons and transposons on the evolution of resistance and virulence
-
Rowe-Magnus DA, Davies J, Mazel D (2002b) Impact of integrons and transposons on the evolution of resistance and virulence. Curr Top Microbiol Immunol 264:167-188
-
(2002)
Curr Top Microbiol Immunol
, vol.264
, pp. 167-188
-
-
Rowe-Magnus, D.A.1
Davies, J.2
Mazel, D.3
-
78
-
-
0034525547
-
Genomics and proteomics tools for the clinic
-
Rudert F (2000) Genomics and proteomics tools for the clinic. Curr Opin Mol Ther 2:633-642
-
(2000)
Curr Opin Mol Ther
, vol.2
, pp. 633-642
-
-
Rudert, F.1
-
80
-
-
0034812782
-
Cathelicidin peptides inhibit multiply antibiotic resistant pathogens from patients with cystic fibrosis
-
Saiman L, Tabibi S, Starner TD, San-Gabriel P, Winokur PL, Hong-Peng J, McCray PB, Tack BF (2001) Cathelicidin peptides inhibit multiply antibiotic resistant pathogens from patients with cystic fibrosis. Antimicrob Agents Chemother 45:2838-2844
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 2838-2844
-
-
Saiman, L.1
Tabibi, S.2
Starner, T.D.3
San-Gabriel, P.4
Winokur, P.L.5
Hong-Peng, J.6
McCray, P.B.7
Tack, B.F.8
-
81
-
-
1642576850
-
Beta-lactam antibiotics: Aspects of manufacture and therapy
-
Osiewacz HD (ed). Springer, Berlin Heidelberg New York
-
Schmidt FR (2002) Beta-lactam antibiotics: aspects of manufacture and therapy. In: Osiewacz HD (ed) The Mycota, vol X: industrial applications. Springer, Berlin Heidelberg New York, pp 69-91
-
(2002)
The Mycota, Vol X: Industrial Applications
, vol.10
, pp. 69-91
-
-
Schmidt, F.R.1
-
82
-
-
0030246884
-
A highly vancomycin resistant laboratory mutant of Staphylococcus aureus
-
Sieradzki K, Tomasz A (1996) A highly vancomycin resistant laboratory mutant of Staphylococcus aureus. FEMS Microbiol Lett 142:161-166
-
(1996)
FEMS Microbiol Lett
, vol.142
, pp. 161-166
-
-
Sieradzki, K.1
Tomasz, A.2
-
83
-
-
0034889119
-
Quorum sensing is a global regulatory mechanism in enterohemorrhagic Escherichia coli O157:H7
-
Sperandio V, Torres AG, Giron JA, Kaper JB (2001) Quorum sensing is a global regulatory mechanism in enterohemorrhagic Escherichia coli O157:H7. J Bacteriol 183:5187-5197
-
(2001)
J Bacteriol
, vol.183
, pp. 5187-5197
-
-
Sperandio, V.1
Torres, A.G.2
Giron, J.A.3
Kaper, J.B.4
-
84
-
-
0035313411
-
Combinatorial biosynthesis of polyketides and nonribosomal peptides
-
Staunton J, Wilkinson B (2001) Combinatorial biosynthesis of polyketides and nonribosomal peptides. Curr Opin Chem Biol 5:159-164
-
(2001)
Curr Opin Chem Biol
, vol.5
, pp. 159-164
-
-
Staunton, J.1
Wilkinson, B.2
-
85
-
-
0035832284
-
Researchers describe latest strategies to combat antibiotic resistant microbes
-
Stephenson J (2001) Researchers describe latest strategies to combat antibiotic resistant microbes. JAMA 285:2317-2318
-
(2001)
JAMA
, vol.285
, pp. 2317-2318
-
-
Stephenson, J.1
-
87
-
-
0033964118
-
High-throughput and ultra-high-throughput screening: Solution- and cell-based approaches
-
Sundberg SA (2000) High-throughput and ultra-high-throughput screening: solution- and cell-based approaches. Curr Opin Biotechnol 11:47-53
-
(2000)
Curr Opin Biotechnol
, vol.11
, pp. 47-53
-
-
Sundberg, S.A.1
-
88
-
-
0033790259
-
Development of daptomycin for Grampositive infections
-
Tally FP, DeBruin F (2000) Development of daptomycin for Grampositive infections. J Antimicrobial Chemotherapy 46:523-526
-
(2000)
J Antimicrobial Chemotherapy
, vol.46
, pp. 523-526
-
-
Tally, F.P.1
DeBruin, F.2
-
89
-
-
0036183822
-
Antimicrobial dendrimeric peptides
-
Tam JP, Lu YA, Yang YL (2002) Antimicrobial dendrimeric peptides. Eur J Biochem 269:923-932
-
(2002)
Eur J Biochem
, vol.269
, pp. 923-932
-
-
Tam, J.P.1
Lu, Y.A.2
Yang, Y.L.3
-
90
-
-
0034724272
-
Heterologous expression in Escherichia coli of the first module of nonribosomal peptide synthase for chloroeremomycin, a vancomycin-type glycopeptide antibiotic
-
Trauger JW, Walsh CT (2000) Heterologous expression in Escherichia coli of the first module of nonribosomal peptide synthase for chloroeremomycin, a vancomycin-type glycopeptide antibiotic. Proc Natl Acad USA 97:3112-3117
-
(2000)
Proc Natl Acad USA
, vol.97
, pp. 3112-3117
-
-
Trauger, J.W.1
Walsh, C.T.2
-
91
-
-
0030958955
-
Quinupristin/Dalfopristin
-
Trautmann M, Ruhnke M, Krsken M, Brauers J, Springsklee M, Marre R (1997) Quinupristin/Dalfopristin. Chemother J 6:31-42
-
(1997)
Chemother J
, vol.6
, pp. 31-42
-
-
Trautmann, M.1
Ruhnke, M.2
Krsken, M.3
Brauers, J.4
Springsklee, M.5
Marre, R.6
-
92
-
-
0032151488
-
Are we facing a "post-antibiotic era"? - A review of the literature regarding antimicrobial drug resistance
-
Trnobranski PH (1998) Are we facing a "post-antibiotic era"? - a review of the literature regarding antimicrobial drug resistance. J Clin Nurs 7:392-100
-
(1998)
J Clin Nurs
, vol.7
, pp. 392-1100
-
-
Trnobranski, P.H.1
-
93
-
-
0034309810
-
Natural antibiotic susceptibility by Listeria species: L. grayi, L. innocua, L. ivanovii, L. monocytogenes, L. seeligeri and L. welshimeri strains
-
Troxler R, von Grävenitz A, Funke G, Wiedemann B, Stock I (2000) Natural antibiotic susceptibility by Listeria species: L. grayi, L. innocua, L. ivanovii, L. monocytogenes, L. seeligeri and L. welshimeri strains. Clin Microbiol Infect 6:525-535
-
(2000)
Clin Microbiol Infect
, vol.6
, pp. 525-535
-
-
Troxler, R.1
Von Grävenitz, A.2
Funke, G.3
Wiedemann, B.4
Stock, I.5
-
94
-
-
0029994714
-
Mechanism of action of streptogramins and macrolides
-
Vannuffel P, Cocito C (1996) Mechanism of action of streptogramins and macrolides. Drugs 51 [Suppl 1]:20-30
-
(1996)
Drugs
, vol.51
, Issue.1 SUPPL.
, pp. 20-30
-
-
Vannuffel, P.1
Cocito, C.2
-
95
-
-
0035396436
-
DNA-chip-based microbiology
-
Versalovic J (2001) DNA-chip-based microbiology. Clin Microbiol Newslett 23:99-102
-
(2001)
Clin Microbiol Newslett
, vol.23
, pp. 99-102
-
-
Versalovic, J.1
-
96
-
-
1642576851
-
-
Lipopetide calcium salts: process for their preparation and their use. European Patent 1068223
-
Vertesy, L, Aretz W, Decker H, Ehlers E, Kurz M, Schmidt FR, Knauf M, Kogler H (1999) Lipopetide calcium salts: process for their preparation and their use. European Patent 1068223
-
(1999)
-
-
Vertesy, L.1
Aretz, W.2
Decker, H.3
Ehlers, E.4
Kurz, M.5
Schmidt, F.R.6
Knauf, M.7
Kogler, H.8
-
97
-
-
0033856211
-
Friulimicins: Novel lipopetide antibiotics with peptidoglycan synthesis inhibiting activity from Actinoplanes friulensis sp. nov. II. Isolation and structural characterization
-
Vertesy L, Ehlers E, Kogler H, Kurz M, Meiwes J, Seibert G, Vogel M, Hammann P (2000) Friulimicins: novel lipopetide antibiotics with peptidoglycan synthesis inhibiting activity from Actinoplanes friulensis sp. nov. II. Isolation and structural characterization. J Antibiot 53:816-827
-
(2000)
J Antibiot
, vol.53
, pp. 816-827
-
-
Vertesy, L.1
Ehlers, E.2
Kogler, H.3
Kurz, M.4
Meiwes, J.5
Seibert, G.6
Vogel, M.7
Hammann, P.8
-
98
-
-
0035553085
-
Bacterial genomics as a potential tool for discovering new antimicrobial agents
-
Waterman SR (2001) Bacterial genomics as a potential tool for discovering new antimicrobial agents. Am J Pharmacogenomics 1:263-269
-
(2001)
Am J Pharmacogenomics
, vol.1
, pp. 263-269
-
-
Waterman, S.R.1
-
99
-
-
0035339864
-
Update on the microbiology of cystic fibrosis: Traditional and emerging pathogens
-
Whittier S (2001) Update on the microbiology of cystic fibrosis: traditional and emerging pathogens. Clin Microbial Newslett 23:67-71
-
(2001)
Clin Microbial Newslett
, vol.23
, pp. 67-71
-
-
Whittier, S.1
-
100
-
-
0003784960
-
-
World Health Organisation, Geneva, Switzerland
-
WHO Report on Infectious Diseases (2000) Overcoming antimicrobial resistance. World Health Organisation, Geneva, Switzerland
-
(2000)
Overcoming Antimicrobial Resistance
-
-
-
102
-
-
0035910508
-
Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity
-
Wiedemann I, Breukink E, Van-Kraaij C, Kuipers OP, Bierbaum G, De Kruijff B, Sahl HG (2001) Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity. J Biol Chem 276:1772-1779
-
(2001)
J Biol Chem
, vol.276
, pp. 1772-1779
-
-
Wiedemann, I.1
Breukink, E.2
Van-Kraaij, C.3
Kuipers, O.P.4
Bierbaum, G.5
De Kruijff, B.6
Sahl, H.G.7
-
103
-
-
1642454439
-
Das ProteinChip-System in klinischer Forschung, Proteinisolierung und Proteinanalytik
-
Wiesner A, Bogumi R (2002) Das ProteinChip-System in klinischer Forschung, Proteinisolierung und Proteinanalytik. Laborwelt, Biocom, April: 10-17
-
(2002)
Laborwelt, Biocom
, vol.APRIL
, pp. 10-17
-
-
Wiesner, A.1
Bogumi, R.2
-
104
-
-
0032549098
-
Containment of antibiotic resistance
-
Williams RJ, Heymann DL (1998) Containment of antibiotic resistance. Science 279:1153-1154
-
(1998)
Science
, vol.279
, pp. 1153-1154
-
-
Williams, R.J.1
Heymann, D.L.2
-
105
-
-
0003505256
-
-
World Health Organisation, Geneva, Switzerland
-
World Health Reports (1996-2001) World Health Organisation, Geneva, Switzerland
-
(1996)
World Health Reports
-
-
-
106
-
-
0035032985
-
Synergistic interactions between mammalian antimicrobial defense peptides
-
Yan H, Hancock REW (2001) Synergistic interactions between mammalian antimicrobial defense peptides. Antimicrob Agents Chemother 45:1558-1560
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 1558-1560
-
-
Yan, H.1
Hancock, R.E.W.2
-
107
-
-
0035313673
-
Industrial biocatalysis
-
Zaks A (2001) Industrial biocatalysis. Curr Opin Chem Biol 5:130-136
-
(2001)
Curr Opin Chem Biol
, vol.5
, pp. 130-136
-
-
Zaks, A.1
-
108
-
-
1642495497
-
The commercial development of the antimicrobial peptide Pexiganan
-
Lohner K (ed). Horizon, Wymondham, Norfolk, UK
-
Zasloff M (2001) The commercial development of the antimicrobial peptide Pexiganan. In: Lohner K (ed) Development of novel antimicrobial agents: emerging strategies. Horizon, Wymondham, Norfolk, UK, pp 262-272
-
(2001)
Development of Novel Antimicrobial Agents: Emerging Strategies
, pp. 262-272
-
-
Zasloff, M.1
-
109
-
-
0037022650
-
Quorum-sensing regulators control virulence gene expression in Vibrio cholerae
-
Zhu J, Miller MB, Vance RE, Dziejman M, Bassler BL, Mekalanos JJ (2002) Quorum-sensing regulators control virulence gene expression in Vibrio cholerae. Proc Natl Acad Sci USA 99:3129-3134
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3129-3134
-
-
Zhu, J.1
Miller, M.B.2
Vance, R.E.3
Dziejman, M.4
Bassler, B.L.5
Mekalanos, J.J.6
-
110
-
-
0022969189
-
Role of branched chain fatty acid precursors in regulating factor profile in the biosynthesis of A21978 C complex
-
Zmijewski MJ, Briggs B, Occolowitz J (1986) Role of branched chain fatty acid precursors in regulating factor profile in the biosynthesis of A21978 C complex. J Antibiot 39:1483-1485
-
(1986)
J Antibiot
, vol.39
, pp. 1483-1485
-
-
Zmijewski, M.J.1
Briggs, B.2
Occolowitz, J.3
|