Trans-synaptic regulation of calmodulin gene expression after experimentally induced orofacial inflammation and subsequent corticosteroid treatment in the principal sensory and motor trigeminal nuclei of the rat

Neurochemistry International

Volumn 52, Issue 1, 2008, Pages 265-271

  Orojan, Ivan ^a,b   Bakota, Lidia ^c   Gulya, Karoly ^c  

^a Municipal Hospital   (Hungary)

^b Regional Outpatient Health Service   (Hungary)

^c UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Calmodulin gene expression; Corticosteroid; Dithranol; Inflammation; Infraorbital skin; Motor trigeminal nucleus; Orofacial skin; Principal sensory nucleus

Indexed keywords

CALMODULIN; DITHRANOL; MESSENGER RNA; MOMETASONE FUROATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CONTROLLED STUDY; CORTICOSTEROID THERAPY; FACE; FROZEN SECTION; GENE EXPRESSION; GENE EXPRESSION REGULATION; IMAGE ANALYSIS; INFLAMMATION; INNERVATION; MALE; MAXILLARY NERVE; MOTOR NERVE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RNA PROBE; SENSORY NERVE; TRIGEMINAL NUCLEUS;

ADRENAL CORTEX HORMONES; ANIMALS; BRAIN; CALMODULIN; FACE; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; INFLAMMATION; MALE; MOUTH; RATS; RATS, SPRAGUE-DAWLEY; SYNAPSES; TRIGEMINAL NERVE;

RATTUS;

EID: 36849023936     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2007.06.015     Document Type: Article

References (44)

1. Arendt-Nielsen L. Induction and assessment of experimental pain from human skin, muscle, and viscera. In: Jensen T.S., Turner J.A., and Wiesenfeld-Hallin Z. (Eds). Proceedings of the 8th World Congress on Pain, Seattle, USA. IASP Press Progr. Pain Res. Managem. 8 (1997) 393-425
2. Bakota L., Orojan I., and Gulya K. Intranuclear differences in calmodulin gene expression in the trigeminal nuclei of the rat. Acta Biol. Szeged 49 (2005) 9-14
3. Carstens E., Kuenzler N., and Handwerker H.O. Activation of neurons in rat trigeminal subnucleus caudalis by different irritant chemicals applied to oral or ocular mucosa. J. Neurophysiol. 80 (1998) 465-492
4. Choi J., Levey A.I., Weintraub S.T., Rees H.D., Gearing M., Chin L.S., and Li L. Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases. J. Biol. Chem. 279 (2004) 13256-13264
5. Das S.K., Tan J., Raja S., Halder J., Paria B.C., and Dey S.K. Estrogen targets genes involved in protein processing, calcium homeostasis, and Wnt signaling in the mouse uterus independent of estrogen receptor-α and -β. J. Biol. Chem. 275 (2000) 28834-28842
6. Doran J.F., Jackson P., Kynoch P.A., and Thompson R.J. Isolation of PGP 9.5, a new human neuron-specific protein detected by high-resolution two-dimesional electrophoresis. J. Neurochem. 40 (1983) 1542-1547
7. Fukushima T., and Kerr F.W.L. Organization of trigemino-thalamic tracts and other thalamic afferent systems of the brainstem in the rat: presence of gelatinosa neurons with thalamic connections. J. Comp. Neurol. 183 (1979) 169-184
8. Gannon M.N., and McEwen B.S. Distribution and regulation of calmodulin mRNAs in rat brain. Mol. Brain Res. 22 (1994) 186-192
9. Hylden J.L., Nahin R.L., Traub R.J., and Dubner R. Expansion of receptive fields of spinal lamina I projection neurons in rats with unilateral adjuvant-induced inflammation: the contribution of dorsal horn mechanisms. Pain 37 (1989) 229-243
10. Ikeda T., Terayama R., Jue S.S., Sugiyo S., Dubner R., and Ren K. Differential rostral projections of caudal brainstem neurons receiving trigeminal input after masseter inflammation. J. Comp. Neurol. 465 (2003) 220-233
11. Kortvely E., and Gulya K. Calmodulin, and various ways to regulate its activity. Life Sci. 74 (2004) 1065-1070
12. Kortvely E., Palfi A., Bakota L., and Gulya K. Ontogeny of calmodulin gene expression in rat brain. Neuroscience 114 (2002) 301-316
13. Lambelet P., Ducret F., Loliger J., Maignan J., Reichert U., and Shroot B. The relevance of secondary radicals in the mode of action of anthralin. Free Radic. Biol. Med. 9 (1990) 183-190
14. Laub M., and Jennissen H.P. Ubiquitination of endogenous calmodulin in rabbit tissue extracts. FEBS Lett. 294 (1991) 229-233
15. McBride S.R., Walker P., and Reynolds N.J. Optimizing the frequency of outpatient short-contact dithranol treatment used in combination with broadband ultraviolet B for psoriasis: a randomized, within-patient controlled trial. Br. J. Dermatol. 149 (2003) 1259-1265
16. Morsink M.C., Steenbergen P.J., Vos J.B., Karst H., Joels M., De Kloet E.R., and Datson N.A. Acute activation of hippocampal glucocorticoid receptors results in different waves of gene expression throughout time. J. Neuroendocrinol. 18 (2006) 239-252
17. Nishida Y., Yoshioka M., and St-Amand J. Regulation of hypothalamic gene expression by glucocorticoid: implications for energy homeostasis. Physiol. Genomics 25 (2006) 96-104
18. Orojan I., Bakota L., and Gulya K. Differential calmodulin gene expression in the nuclei of the rat midbrain-brain stem region. Acta Histochem. 108 (2006) 455-462
19. Orojan I., Szigeti C., Varszegi S., and Gulya K. Dithranol abolishes UCH-L1 immunoreactivity in the nerve fibers of the rat orofacial skin. Brain Res. 1121 (2006) 216-220
20. Palfi A., and Gulya K. Water deprivation upregulates the three calmodulin genes in exclusively the supraoptic nucleus of the rat brain. Mol. Brain Res. 74 (1999) 111-116
21. Palfi A., Hatvani L., and Gulya K. A new quantitative film autoradiographic method of quantifying mRNA trancripts for in situ hybridization. J. Histochem. Cytochem. 46 (1998) 1141-1149
22. Palfi A., Kortvely E., Fekete E., Kovacs B., Varszegi S., and Gulya K. Differential calmodulin gene expression in the rodent brain. Life Sci. 70 (2002) 2829-2855
23. Palfi A., Simonka J.A., Pataricza M., Tekulics P., Lepran I., Papp G., and Gulya K. Postischemic calmodulin gene expression in the rat hippocampus. Life Sci. 68 (2001) 2373-2381
24. Palfi A., Vizi S., and Gulya K. Differential distribution and intracellular targeting of mRNAs corresponding to the three calmodulin genes in rat brain: a quantitative in situ hybridization study. J. Histochem. Cytochem. 47 (1999) 583-600
25. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates. 3rd ed. (1997), Academic Press, San Diego
26. Qin Y., Nair S., Karst H., Vreugdenhil E., Datson N., and Joels M. Gene expression changes in single dentate granule neurons after adrenalectomy of rats. Mol. Brain Res. 111 (2003) 17-23
27. Shen C., Ye Y., Robertson S.E., Lau A.W., Mak D.O., and Chou M.M. Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6. J. Biol. Chem. 280 (2005) 35967-35973
28. Shroot B., and Brown C. Free radicals in skin exposed to dithranol and its derivatives. Arzneilmittelforsch 36 (1986) 1253-1255
29. Sola C., Tusell J.M., and Serratosa J. Comparative study of the pattern of expression of calmodulin messenger RNAs in the mouse brain. Neuroscience 75 (1996) 245-256
30. Swinkels O.Q., Kucharekova M., Prins M., Gerritsen M.J., van der Valk P.G., and van de Kerkhof P.C. The effects of topical corticosteroids and a coal tar preparation on dithranol-induced irritation in patients with psoriasis. Skin Pharmacol. Appl. Skin Physiol. 16 (2003) 12-17
31. Swinkels O.Q., Prins M., Birker L.W., Gerritsen M.J., van der Valk P.G., and van de Kerkhof P.C. The response of normal human skin to single and repeated applications of dithranol cream: an immunohistochemical assessment. Skin Pharmacol. Appl. Skin Physiol. 15 (2002) 262-269
32. Swinkels O.Q., Prins M., Gerritsen M.J., van Vlijmen-Willems I.M., van der Valk P.G., and van de Kerkhof P.C. An immunohistochemical assessment of the response of the psoriatic lesion to single and repeated applications of high-dose dithranol cream. Skin Pharmacol. Appl. Skin Physiol. 15 (2002) 393-400
33. Swinkels O.Q., Prins M., Tosserams E.F., Gerritsen M.J., van Der Valk P.G., and van de Kerkhof P.C. The influence of a topical corticosteroid on short-contact high-dose dithranol therapy. Br. J. Dermatol. 145 (2001) 63-69
34. Swinkels O.Q., Prins M., van Vlijmen-Willems I.M., Gerritsen M.J., van der Valk P.G., and van de Kerkhof P.C. The response of uninvolved skin of patients with psoriasis to single and repeated applications of dithranol cream: an immunohistochemical assessment. Skin Pharmacol. Appl. Skin Physiol. 15 (2002) 385-392
35. Toutenhoofd S.L., and Strehler E.E. The calmodulin multigene family as a unique case of genetic redundancy: multiple levels of regulation to provide spatial and temporal control of calmodulin pools?. Cell Calcium 28 (2000) 83-96
36. Travers J.B. Oromotor nuclei. In: Paxinos G. (Ed). The Rat Nervous System. Second ed. (1995), Academic Press, San Diego 239-255
37. Travers J.B., and Norgren R. Afferent projections to the oral motor nuclei of the rat. J. Comp. Neurol. 220 (1983) 280-298
38. Vizi S., Palfi A., and Gulya K. Multiple calmodulin genes exhibit systematically differential responses to chronic ethanol treatment and withdrawal in several regions of the rat brain. Mol. Brain Res. 83 (2000) 63-71
39. Vizi S., Palfi A., Hatvani L., and Gulya K. Methods for quantification of in situ hybridization signals obtained by film autoradiography and phosphorimaging applied for estimation of regional levels of calmodulin mRNA classes in the rat brain. Brain Res. Protoc. 8 (2001) 32-44
40. Waite P.M.E., and Tracey D.J. Trigeminal sensory system. In: Paxinos G. (Ed). The Rat Nervous System. Second ed. (1995), Academic Press, San Diego 705-724
41. Zhang J., and Madden T.L. PowerBLAST: new network BLAST application for interactive or automated sequence analysis and annotation. Genome Res. 7 (1997) 649-656
42. Zhou Q., Imbe H., Dubner R., and Ren K. Persistent Fos protein expression after orofacial deep or cutaneous tissue inflammation in rats: implications for persistent orofacial pain. J. Comp. Neurol. 412 (1999) 276-291
43. Ziegenhagen R., Gehrke P., and Jennissen H.P. Covalent conjugation of mammalian calmodulin with ubiquitin. FEBS Lett. 237 (1988) 103-107
44. Ziegenhagen R., Goldberg M., Rakutt W.D., and Jennissen H.P. Multiple ubiquitination of calmodulin results in one polyubiquitin chain linked to calmodulin. FEBS Lett. 271 (1990) 71-75