In situ determination of partition and diffusion coefficients in the lipid bilayers of Stratum corneum

Pharmaceutical Research

Volumn 17, Issue 8, 2000, Pages 1026-1029

  Mitragotri, S ^a,b  

^a University of California at Santa Barbara   (United States)

^b NONE

Author keywords

Diffusion coefficient; Model; Non intrusive; Partition coefficient; Transdermal

Indexed keywords

1 NAPHTHOL; ALDOSTERONE; CORTICOSTERONE; DECANOL; ESTRADIOL; LIDOCAINE; OCTANOL; PROGESTERONE; TESTOSTERONE;

ARTICLE; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; DRUG METABOLISM; DRUG PENETRATION; DRUG RELEASE; FIRST PASS EFFECT; HUMAN; HUMAN TISSUE; LIPID BILAYER; MATHEMATICAL ANALYSIS; MEASUREMENT; PARTITION COEFFICIENT; PRIORITY JOURNAL; SKIN; SKIN ABSORPTION; SKIN PERMEABILITY; STRATUM CORNEUM;

ADMINISTRATION, CUTANEOUS; ALGORITHMS; DIFFUSION; HUMANS; LIPID BILAYERS; MOLECULAR WEIGHT; PHARMACEUTICAL PREPARATIONS; SKIN; SOLUBILITY;

EID: 0033795387     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007547809430     Document Type: Article

References (12)

1. A theoretical analysis of partitioning, diffusion, and permeation across lipid bilayers
2. Lateral diffusion of small compounds in human stratum corneum and model lipid bilayer systems
3. Percutaneous transport in relation to stratum corneum structure and lipid composition
4. Evaluation of solute permeation through the stratum corneum: Lateral bilayer diffusion as the primary transport mechanism
5. Synergistic effect of ultrasound and chemical enhancers on transdermal drug delivery
6. Transdermal drug delivery using low-frequency sonophoresis
7. A mechanistic study of ultrasonically enhanced transdermal drug delivery
8. Determination of the threshold energy dose for ultrasound-induced transdermal drug delivery
9. Heterogenity effects of permeability-partition coefficient relationship in human stratum corneum