메뉴 건너뛰기




Volumn 117, Issue 12, 2007, Pages 3658-3660

Targeting mutant p53 shows promise for sunscreens and skin cancer

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 DIMETHYLAMINOPROPYLAMINO) 2 (4 METHOXYSTYRYL)QUINAZOLINE; CYCLOSPORIN; FLUOROURACIL; IMIQUIMOD; MUTANT PROTEIN; PROTEIN P53; SUNSCREEN;

EID: 36849006530     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI34251     Document Type: Review
Times cited : (11)

References (20)
  • 1
    • 34548398873 scopus 로고    scopus 로고
    • American Cancer Society
    • American Cancer Society. 2007. Skin cancer facts. http://www.cancer.org/ docroot/PED/content/ped_7_1_What_You_Need_To_Know_About_Skin_Cancer.asp? sitearea=PED.
    • (2007) Skin cancer facts
  • 3
    • 0025719491 scopus 로고
    • A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma
    • Brash, D.E., et al. 1991. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc. Natl. Acad. Sci. U. S. A. 88:10124-10128.
    • (1991) Proc. Natl. Acad. Sci. U. S. A , vol.88 , pp. 10124-10128
    • Brash, D.E.1
  • 4
    • 34047118665 scopus 로고    scopus 로고
    • Analysis of skin cancer risk factors in immunosuppressed renal transplant patients shows high levels of UV-specific tandem CC to TT mutations of the p53 gene
    • Queille, S., et al. 2007. Analysis of skin cancer risk factors in immunosuppressed renal transplant patients shows high levels of UV-specific tandem CC to TT mutations of the p53 gene. Carcinogenesis. 28:724-731.
    • (2007) Carcinogenesis , vol.28 , pp. 724-731
    • Queille, S.1
  • 6
    • 0037240438 scopus 로고    scopus 로고
    • p53 mutations in human aggressive and nonaggressive basal and squamous cell carcinomas
    • Bolshakov, S., et al. 2003. p53 mutations in human aggressive and nonaggressive basal and squamous cell carcinomas. Clin. Cancer Res. 9:228-234.
    • (2003) Clin. Cancer Res , vol.9 , pp. 228-234
    • Bolshakov, S.1
  • 7
    • 0032694528 scopus 로고    scopus 로고
    • Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice
    • Aszterbaum, M., et al. 1999. Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice. Nat. Med. 5:1285-1291.
    • (1999) Nat. Med , vol.5 , pp. 1285-1291
    • Aszterbaum, M.1
  • 8
    • 33847619209 scopus 로고    scopus 로고
    • Recruiting the cell's own guardian for cancer therapy
    • Marx, J. 2007. Recruiting the cell's own guardian for cancer therapy. Science. 315:1211-1213.
    • (2007) Science , vol.315 , pp. 1211-1213
    • Marx, J.1
  • 9
    • 0029888514 scopus 로고    scopus 로고
    • Biological and clinical importance of the p53 tumor suppressor gene
    • Velculescu, V.E., and El-Deiry, W.S. 1996. Biological and clinical importance of the p53 tumor suppressor gene. Clin. Chem. 42:858-868.
    • (1996) Clin. Chem , vol.42 , pp. 858-868
    • Velculescu, V.E.1    El-Deiry, W.S.2
  • 10
    • 0030968938 scopus 로고    scopus 로고
    • Sunlight and skin cancer: Inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens
    • Ananthaswamy, H.N., et al. 1997. Sunlight and skin cancer: inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens. Nat. Med. 3:510-514.
    • (1997) Nat. Med , vol.3 , pp. 510-514
    • Ananthaswamy, H.N.1
  • 11
    • 36849059300 scopus 로고    scopus 로고
    • Melanoma and other skin cancers
    • R. Pazdur, L.R. Coia, W.J. Hoskins, and L.D. Wagman, editors. 9th edition. CMP Healthcare Media. San Francisco, California, USA
    • Jensen, E.H., Margolin, K.A., and Sondak, V.K. 2005. Melanoma and other skin cancers. In Cancer management: a multidisciplinary approach. R. Pazdur, L.R. Coia, W.J. Hoskins, and L.D. Wagman, editors. 9th edition. CMP Healthcare Media. San Francisco, California, USA. 531-561.
    • (2005) Cancer management: A multidisciplinary approach , pp. 531-561
    • Jensen, E.H.1    Margolin, K.A.2    Sondak, V.K.3
  • 13
    • 0033601370 scopus 로고    scopus 로고
    • Pharmacological rescue of mutant p53 conformation and function
    • Foster, B.A., Coffey, H.A., Morin, M.J., and Rastinejad, F. 1999. Pharmacological rescue of mutant p53 conformation and function. Science. 286:2507-2510.
    • (1999) Science , vol.286 , pp. 2507-2510
    • Foster, B.A.1    Coffey, H.A.2    Morin, M.J.3    Rastinejad, F.4
  • 14
    • 0037370357 scopus 로고    scopus 로고
    • Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at serine 15 or 20 or MDM2 binding
    • Wang, W., Takimoto, R., Rastinejad, F., and El-Deiry, W.S. 2003. Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at serine 15 or 20 or MDM2 binding. Mol. Cell. Biol. 23:2171-2181.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 2171-2181
    • Wang, W.1    Takimoto, R.2    Rastinejad, F.3    El-Deiry, W.S.4
  • 15
    • 85047687410 scopus 로고    scopus 로고
    • The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein
    • Takimoto, R., et al. 2002. The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein. Cancer Biol. Ther. 1:47-55.
    • (2002) Cancer Biol. Ther , vol.1 , pp. 47-55
    • Takimoto, R.1
  • 16
    • 0037192628 scopus 로고    scopus 로고
    • Characterization of the p53-rescue drug CP-31398 in vitro and in living cells
    • Rippin, T.M., et al. 2002. Characterization of the p53-rescue drug CP-31398 in vitro and in living cells. Oncogene. 21:2119-2129.
    • (2002) Oncogene , vol.21 , pp. 2119-2129
    • Rippin, T.M.1
  • 17
    • 36849084779 scopus 로고    scopus 로고
    • CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice
    • Tang, X., et al. 2007. CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice. J. Clin. Invest. 117:3753-3764.
    • (2007) J. Clin. Invest , vol.117 , pp. 3753-3764
    • Tang, X.1
  • 18
    • 33748670457 scopus 로고    scopus 로고
    • The pathological response to DNA damage does not contribute to p53-mediated tumour suppression
    • Christophorou, M.A., et al. 2006. The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature. 443:214-217.
    • (2006) Nature , vol.443 , pp. 214-217
    • Christophorou, M.A.1
  • 19
    • 33846440113 scopus 로고    scopus 로고
    • An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells
    • Smalley, K.S., et al. 2007. An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells. Cancer Res. 67:209-217.
    • (2007) Cancer Res , vol.67 , pp. 209-217
    • Smalley, K.S.1
  • 20
    • 36849089479 scopus 로고    scopus 로고
    • Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation
    • Talalay, P., et al. 2007. Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation. Proc. Natl. Acad. Sci. U. S. A. 104:17500-17505.
    • (2007) Proc. Natl. Acad. Sci. U. S. A , vol.104 , pp. 17500-17505
    • Talalay, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.