Development and application of a validated HPLC method for the analysis of dissolution samples of gabapentin drug products

Journal of Pharmaceutical and Biomedical Analysis

Volumn 46, Issue 1, 2008, Pages 181-186

  Gupta, Abhay ^a   Ciavarella, Anthony B ^a   Sayeed, Vilayat A ^a   Khan, Mansoor A ^a   Faustino, Patrick J ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Dissolution; Drug products; Gabapentin; HPLC; Impurity; Lactam

Indexed keywords

2 PYRROLIDINONE; ACETONITRILE; GABAPENTIN; HYDROGEN; METHANOL; PHOSPHATE; POTASSIUM;

ACCURACY; ARTICLE; DRUG SOLUBILITY; DRUG STRUCTURE; ELUTION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; PH MEASUREMENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; ULTRAVIOLET RADIATION;

ACETONITRILES; AMINES; ANTICONVULSANTS; CALIBRATION; CAPSULES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOHEXANECARBOXYLIC ACIDS; DRUG CONTAMINATION; DRUG STABILITY; FURANS; GAMMA-AMINOBUTYRIC ACID; HYDROGEN-ION CONCENTRATION; LACTAMS; LINEAR MODELS; METHANOL; MOLECULAR STRUCTURE; REPRODUCIBILITY OF RESULTS; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; SPIRO COMPOUNDS; TABLETS; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS;

EID: 36749089958     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2007.08.023     Document Type: Article

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