Sensitive microanalysis of gabapentin by high-performance liquid chromatography in human serum using pre-column derivatization with 4-chloro-7-nitrobenzofurazan: Application to a bioequivalence study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 837, Issue 1-2, 2006, Pages 24-28

  Bahrami, Gholamreza ^a,b   Mohammadi, Bahareh ^a  

^a KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

4 Chloro 7 nitrobenzofurazan; Gabapentin; HPLC; NBD Cl; Serum

Indexed keywords

ALDEHYDES; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NITROGEN COMPOUNDS; PLASMAS; SENSITIVITY ANALYSIS;

4-CHLORO-7-NITROBENZOFURAZAN; GABAPENTIN; NBD-CL; SERUM;

METABOLITES;

4 CHLORO 7 NITROBENZOFURAZAN; ACETONITRILE; AMLODIPINE; ANTICONVULSIVE AGENT; GABAPENTIN; METHANOL; SODIUM DIHYDROGEN PHOSPHATE; TRIETHYLAMINE;

ARTICLE; BIOEQUIVALENCE; CALIBRATION; CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DERIVATIZATION; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NORMAL HUMAN; PRECIPITATION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; STATISTICAL SIGNIFICANCE;

4-CHLORO-7-NITROBENZOFURAZAN; AMINES; ANTICONVULSANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOHEXANECARBOXYLIC ACIDS; GAMMA-AMINOBUTYRIC ACID; HUMANS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; THERAPEUTIC EQUIVALENCY;

EID: 33646871785     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.03.056     Document Type: Article

References (16)

1. Porter R.J., and Meldrum B.S. Antiseizure Drugs. In: Katzung B.G. (Ed). Basic and Clinical pharmacology. Ninth ed. (2004), The McGraw-Hill Companies, New York NY 388
2. Brown P.I., McMillin G.A., and Urry F.M. Clin. Chem. 49 7 (2003) 1198
3. Zhu Z., and Neirinck L. J. Chromatogr. B 779 (2002) 307
4. Krivanek P., Koppatz K., and Turnheim K. Ther. Drug Monit. 25 3 (2003) 374
5. Ratnaraj N., and Patsalos P.N. Ther. Drug Monit. 20 4 (1998) 430
6. Chollet D.F., Goumaz L., Juliano C., and Anderegg G. J. Chromatogr. B 746 (2000) 311
7. Gauthier D., and Gupta R. Clin. Chem. 48 (2002) 2259
8. Tang P.H., Miles M.V., Glauser T.A., and DeGrauw T. J. Chromatogr. B 727 (1999) 125
9. Jiang Q., and Li S. J. Chromatogr. B 727 (1999) 119
10. Vermeij T.A.C., and Edelbroek P.M. J. Chromatogr. B 810 (2004) 297
11. Forrest G., Sills G.J., Leach J.P., and Brodie M.J. J. Chromatogr. B 681 (1996) 421
12. Carlsson K.C., and Reubsaet J.L.E. J. Pharm. Biomed. Anal. 34 (2004) 415
13. Ifa D.R., Falci M., Moraes M.E., Bezerra F.A., Moraes M.O., and de Nucci G. J. Mass. Spectrom. 36 (2001) 188
14. Borrey D.C.R., Godderis K.O., Engelrelst V.I.L., Bernard D.R., and Langlois M.R. Clin. Chim. Acta 354 (2005) 147
15. Liliana Garcia L., Shihabi Z.K., and Oles K. J. Chromatogr. B 669 (1995) 157
16. Chang S.Y., and Wang F.Y. J. Chromatogr. B 799 (2004) 265