The Y111H (T415C) polymorphism in exon 3 of the gene encoding adiponectin is uncommon in Polish obese patients

Hormone and Metabolic Research

Volumn 39, Issue 11, 2007, Pages 797-800

  Owecki, M ^a   Miczke, A ^a   Kaczmarek, M ^b   Hoppe Golebiewska J ^b   Pupek Musialik, D ^a   Slomski R ^b   Bryll, W ^a   Cymerys, M ^a   Nikisch, E ^a   Sowinski J ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b INSTITUTE OF HUMAN GENETICS   (Poland)

Author keywords

Adiponectin; Gene; Metabolism; Obesity; Single nucleotide polymorphism

Indexed keywords

ADIPONECTIN; GENOMIC DNA; GLUCOSE; GLYCOSYLATED HEMOGLOBIN; HISTONE; INSULIN; TYROSINE;

ADULT; AGED; ARTICLE; BODY FAT; BODY MASS; CONTROLLED STUDY; DNA EXTRACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXON; FEMALE; GENETIC POLYMORPHISM; GENETIC SCREENING; GENOTYPE; GLUCOSE BLOOD LEVEL; HETEROZYGOTE; HUMAN; INSULIN BLOOD LEVEL; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; OBESITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM; WAIST CIRCUMFERENCE; BLOOD; COMPARATIVE STUDY; GENETICS; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; PHYSIOLOGY; POLAND;

ADIPONECTIN; ADIPOSITY; ADULT; BLOOD GLUCOSE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN; MALE; MIDDLE AGED; OBESITY; POLAND; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 36749036092     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-991155     Document Type: Article

References (34)

1. Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 1995; 270: 26746-26749
2. Hu E, Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 1996; 271: 10697-10703
3. Maeda K, Okubo K, Shimomura I, Funahashi T Matsuzawa Y, Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (Adipose most abundant gene transcript 1). Biochem Biophys Res Commun 1996; 221: 286-289
4. Nakano Y, Tobe T, Choi-Miura N, Mazda T, Tomita M. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem 1996; 120: 803-812
5. Stefan N, Stumvoll M. Adiponectin - its role in metabolism and beyond. Horm Metab Res 2002; 34: 469-474
6. Berg AH, Combs TP, Scherer PE. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 2002; 13: 84-89
7. Pellme F, Smith U, Funahashi T, Matsuzawa Y, Brekke H, Wiklund O, Taskinen MR, Janssen PA. Circulating adiponectin levels are reduced in nonobese but insulin-resistant first-degree relatives of type 2 diabetic patients. Diabetes 2003; 52: 1182-1186
8. Mantzoros CS, Li T, Manson JE, Meigs JB, Hu FB. Circulating adiponectin levels are associated with better glycemic control, more favorable lipid profile, and reduced inflammation in women with type 2 diabetes. J Clin Endocrinol Metab 2005; 90: 4542-4548
9. Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE. Tataranni PA. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001; 86: 1930-1935
10. Thamer C, Haap M, Heller E, Joel L, Braun S, Tschritter O. Haring H, Pritsche A. Beta cell function, insulin resistance and plasma adiponectin concentrations are predictors for the change of postprandial glucose in non-diabetic subjects at risk for type 2 diabetes. Horm Metab Res 2006; 38: 178-182
11. Kern PA, Di Gregorio GB, Lu T, Rassouli N, Ranganathan G. Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor- expression. Diabetes 2003; 52: 1779-1785
12. Nassis GP, Papantakou K, Skenderi K, Triandafillopoulou M, Kavouras SA, Yannakoulia M, Chrousos GP, Sidossis LS. Aerobic exercise training improves insulin sensitivity without changes in body weight, body fat, adiponectin, and inflammatory markers in overweight and obese girls. Metabolism 2005; 54: 1472-1479
13. Kaser S, Moschen A, Kaser A, Ludwiczek O, Ebenbichler CF, Vogel W, Jaschke W, Patsch JR, Tilg H. Circulating adiponectin reflects severity of liver disease but not insulin sensitivity in liver cirrhosis. J Intern Med 2005; 258: 274-280
14. Bacha F, Saad R, Gungor N, Arslanian SA. Does adiponectin explain the lower insulin sensitivity and hyperinsulinemia of African-American children? Pediatr Diabetes 2005; 6: 100-102
15. Vozarova B, Stefan N, Lindsay RS, Krakoff J, Knowler WC, Funahashi T, Matsuzawa Y, Stumvoll M, Weyer C, Tataranni PA. Low plasma adiponectin concentrations do not predict weight gain in humans. Diabetes 2002; 51: 2964-2967
16. Staiger K, Stefan N, Staiger H, Brendel MD, Brandhorst D, Bretzel RG, Machicao F, Kellerer M, Stumvoll M, Fritsche A, Haring HU. Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis. J Clin Endocrinol Metab 2005; 90: 6707-6713
17. Ferris WF, Naran NH, Crowther NJ, Rheeder P, Merwe L van der, Chetty N. The relationship between insulin sensitivity and serum adiponectin levels in three population groups. Horm Metab Res 2005; 37: 695-701
18. Abbasi F, Lamendola C, MacLaughlin T, Hayden J, Reaven GM, Reaven PD. Plasma adiponectin concentrations do not increase in association with moderate weight loss in insulin-resistant, obese women. Metabolism 2004; 53: 280-283
19. Vionnet N, Hani El-H, Dupont S, Gallina S, Francke S, Dotte S, Matos F De, Durand E, Lepretre F, Lecoeur C, Gallina P, Zekiri L, Dina C, Froguel P. Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24. Am J Hum Genet 2000; 67: 1470-1480
20. Kissebah AH, Sonnenberg GE, Myklebust J, Goldstein M, Broman K, James RG, Marks JA, Krakower GR, Jacob HJ, Weber J, Martin L, Blangero J, Comuzzie AG. Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome. Proc Natl Acad Sci USA 2000; 97: 14478-14483
21. Vozarova de Courten B, Hanson RL, Funahashi T, Lindsay RS, Matsuzawa Y, Tanaka S, Thameem F, Gruber JD, Froguel P, Wolford JK. Common polymorphisms in the adiponectin gene ACDC are not associated with diabetes in Pima Indians. Diabetes 2005; 54: 284-289
22. Schäffler A, Barth N, Palitzsch K-D, Drobnik W, Schölmerich J, Schmitz G. Mutation analysis of the human adipocyte-specific apM-1 gene. Eur J Clin Invest 2000; 30: 879-887
23. Zietz B, Barth N, Schölmerich J, Schmitz G, Schäffler A. Gly15Gly polymorphism within the human adipocyte-specific apM-1gene but not Tyr111 His polymorphism is associated with higher levels of cholesterol and LDL-cholesterol in Caucasian patients with type 2 diabetes. Exp Clin Endocrinol Diabetes 2001; 109: 320-325
24. Schäffler A, Herfarth H, Paul G, Ehling A, Müller-Ladner U, Schölmerich J, Zietz B. Identification of influencing variables on adiponectin serum levels in diabetes mellitus type 1 and type 2. Exp Clin Endocrinol Diabetes 2004; 112: 383-389
25. Ukkola O, Ravussin E, Jacobson P, Sjöström L, Bouchard C. Mutations in the adiponectin gene in lean and obese subjects from the Swedish obese subjects cohort. Metabolism 2003; 52: 881-884
26. Ukkola O, Santaniemi M, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bergman R, Kesaniemi YA, Bouchard C. Adiponectin polymorphisms, adiposity and insulin metabolism: HERITAGE family study and Oulu diabetic study. Ann Med 2005; 37: 141-150
27. Vasseur F, Helbecque N, Dina C, Lobbens S, Delannoy V, Gaget S, Boutin P, Vaxillaire M, Lepretre F, Dupont S, Hara K, Clement K, Bihain B, Kadowaki T, Froguel P. Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians. Hum Mol Genet 2002; 11: 2607-2614
28. Østergård T, Ek J, Hamid Y, Saltin B, Pedersen OB, Hansen T, Schmitz O. Influence of the PPAR-gamma2 Pro12Ala and ACE I/D polymorphisms on insulin sensitivity and training effects in healthy offspring of type 2 diabetic subjects. Horm Metab Res 2005; 37: 99-105
29. Gouni-Berthold I, Giannakidou E, Faust M, Berthold HK, Krone W. The K121Q polymorphism of the plasma cell glycoprotein-1 gene is not associated with diabetes mellitus type 2 in German Caucasians. Horm Metab Res 2006; 38: 524-529
30. Li Y, Fisher E, Klapper M, Boeing H, Pfeiffer A, Hampe J, Schreiber S, Burwinkel B, Schrezenmeir J, Döring F. Association between functional FABP2 promoter haplotype and type 2 diabetes. Horm Metab Res 2006; 38: 300-307
31. Fisher E, Li Y, Burwinkel B, Kühr V, Hoffmann K, Möhlig M, Spranger J, Pfeiffer A, Boeing H, Schrezenmeir J, Döring F. Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort. Horm Metab Res 2006; 38: 341-345
32. Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, Yamauchi T, Otabe S, Okada T, Eto K, Kadowaki H, Hagura R, Akanuma Y, Yazaki Y, Nagai R, Taniyama M, Matsubara K, Yoda M, Nakano Y, Tomita M, Kimura S, Ito C, Froguel P, Kadowaki T. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes 2002; 51: 536-540
33. Stumvoll M, Tschritter O, Fritsche A, Staiger H, Renn W, Weisser M, Machicao F, Haring H. Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. Diabetes 2002; 51: 37-41
34. Menzaghi C, Ercolino T, Di Paola R, Berg AH, Warram JH, Scherer PE, Trischitta V, Doria A. A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. Diabetes 2002; 51: 2306-2312