Synthesis of 5-(4-hydroxy-3-methylphenyl)-5-(substituted phenyl)-4, 5-dihydro-1H-1-pyrazolyl-4-pyridylmethanone derivatives with anti-viral activity

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 22, Issue 6, 2007, Pages 702-708

  Ali, Mohamed Ashraf ^a   Shaharyar, Mohammad ^a   De Clercq, Erick ^b  

^a HAMDARD UNIVERSITY   (India)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Anti viral; Herpes simplex; Pyrazoline

Indexed keywords

5 (2 BROMOVINYL) 2' DEOXYURIDINE; 5 (2' CHLOROPHENYL) 3 (4' HYDROXY 3' METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 5 (2' FURYL) 3 (4' HYDROXY 3' METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 5 (2',6' DICHLOROPHENYL) 3 (4' HYDROXY 3' METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 5 (3',4' DIMETHOXYPHENYL) 3 (4' HYDROXY 3' METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 5 (4' CHLOROPHENYL) 3 (4' HYDROXY 3 METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 5 (4' DIMETHYLAMINOPHENYL) 3 (4' HYDROXY 3' METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 5 (4' FLUOROPHENYL) 3 (4' HYDROXY 3' METHYLPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 5 (4' HYDROXY 3' METHYLPHENYL) 5 (3' NITROPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 5 (4' HYDROXY 3' METHYLPHENYL) 5 (3',4',5' TRIMETHOXYPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 5 (4' HYDROXY 3' METHYLPHENYL) 5 (4' METHOXYPHENYL) 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 5 (4' HYDROXY 3' METHYLPHENYL) 5 PHENYL 4,5 DIHYDRO 1H 1 PYRAZOLYL 4 PYRIDYLMETHANONE; 9 (2,3 DIHYDROXYPROPYL)ADENINE; ACICLOVIR; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; CHALCONE DERIVATIVE; GANCICLOVIR; ISONIAZID; RIBAVIRIN; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HELA CELL; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VACCINIA VIRUS; VESICULAR STOMATITIS VIRUS;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CERCOPITHECUS AETHIOPS; CYTOPATHOGENIC EFFECT, VIRAL; DOGS; HUMANS; MOLECULAR STRUCTURE; PYRAZOLES; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

HERPES;

EID: 36749016773     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360701265832     Document Type: Article

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