Kinetic evidence for a ligand-binding-induced conformational transition in the T cell receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 42, 2007, Pages 16639-16644

  Gakamsky, Dmitry M ^a,f   Lewitzki, Erwin ^b   Grell, Ernst ^b   Saulquin, Xavier ^c   Malissen, Bernard ^d   Montero Julian, Felix ^e   Bonneville, Marc ^c,e   Pecht, Israel ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

^c INSERM   (France)

^d CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^e Immunotech   (France)

^f Edinburgh Instruments   (United Kingdom)

Author keywords

Conformational changes; FRET; Induced fit; Stopped flow; T cell receptor ligand interactions

Indexed keywords

CYTOMEGALOVIRUS ANTIGEN PP65; HLA A ANTIGEN; T LYMPHOCYTE RECEPTOR;

ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ENTHALPY; ENTROPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; KINETICS; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN INTERACTION; THERMODYNAMICS;

FLUORESCENCE RESONANCE ENERGY TRANSFER; HLA-A ANTIGENS; HUMANS; KINETICS; LIGANDS; PHOSPHOPROTEINS; PROTEIN CONFORMATION; RECEPTORS, ANTIGEN, T-CELL; SURFACE PLASMON RESONANCE; THERMODYNAMICS; VIRAL MATRIX PROTEINS;

CYTOMEGALOVIRUS;

EID: 36749009635     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0707061104     Document Type: Article

References (27)

1. Davis MM, Boniface JJ, Reich Z, Lyons D, Hampl J, Arden B, Chien Y (1998) Annu Rev Immunol 16:523-544.
2. Germain RN, Stefanova I (1999) Annu Rev Immunol 17:467-522.
3. van der Merwe PA, Davis SJ (2003) Annu Rev Immunol 21:659-684.
4. Alam SM, Davies GM, Lin CM, Zal T, Nasholds W, Jameson SC, Hogquist KA, Gascoigne NR, Travers PJ (1999) Immunity 10:227-237.
5. Baker BM, Gagnon SJ, Biddison WE, Wiley DC (2000) Immunity 13:475-484.
6. Rudolph MG, Wilson IA (2002) Curr Opin Immunol 14:52-65.
7. Kageyama S, Tsomides TJ, Sykulev Y, Eisen HN (1995) J Immunol 154:567-576.
8. Lee JK, Stewart-Jones G, Dong T, Harlos K, Di Gleria K, Dorrell L, Douek DC, van der Merwe PA, Jones EY, McMichael AJ (2004) J Exp Med 200:1455-1466.
9. Martinez-Hackert E, Anikeeva N, Kalams SA, Walker BD, Hendrickson WA, Sykulev Y (2006) J Biol Chem 281:20205-20212.
10. Reiser JB, Darnault C, Gregoire C, Mosser T, Mazza G, Kearney A, van der Merwe PA, Fontecilla-Camps JC, Housset D, Malissen B (2003) Nat Immunol 4:241-247.
11. Rudolph MG, Stanfield RL, Wilson IA (2006) Annu Rev Immunol 24:419-466.
12. Garcia KC, Teyton L, Wilson IA (1999) Annu Rev Immunol 17:369-397.
13. Reiser JB, Gregoire C, Darnault C, Mosser T, Guimezanes A, Schmitt-Verhulst AM, Fontecilla-Camps JC, Mazza G, Malissen B, Housset D (2002) Immunity 16:345-354.
14. Garcia KC, Degano M, Pease LR, Huang M, Peterson PA, Teyton L, Wilson IA (1998) Science 279:1166-1172.
15. Willcox BE, Gao GF, Wyer JR, Ladbury JE, Bell JI, Jakobsen BK, van der Merwe PA (1999) Immunity 10:357-365.
16. Wu LC, Tuot DS, Lyons DS, Garcia KC, Davis MM (2002) Nature 418:552-556.
17. Borg NA, Ely LK, Beddoe T, Macdonald WA, Reid HH, Clements CS, Purcell AW, Kjer-Nielsen L, Miles JJ, Burrows SR, et al. (2005) Nat Immunol 6:171-180.
18. Gakamsky DM, Luescher IF, Pecht I (2004) Proc Natl Acad Sci USA 101:9063-9066.
19. Ely LK, Beddoe T, Clements CS, Matthews JM, Purcell AW, Kjer-Nielsen L, McCluskey J, Rossjohn J (2006) Proc Natl Acad Sci USA 103:6641-6646.
20. Boniface JJ, Reich Z, Lyons DS, Davis MM (1999) Proc Natl Acad Sci USA 96:11446-11451.
21. Krogsgaard M, Prado N, Adams EJ, He XL, Chow DC, Wilson DB, Garcia KC, Davis MM (2003) Mol Cell 12:1367-1378.
22. Haugland RP (2002) The Handbook: A Guide to Fluorescent Probes and Labeling Technologies (Invitrogen/Molecular Probes, Carlsbad, CA), 9th Ed, pp 48 and 58.
23. Gao GF, Rao Z, Bell JI (2002) Trends Immunol 23:408-413.
24. Gakamsky DM, Luescher IF, Pramanik A, Kopito RB, Lemonnier F, Vogel H, Rigler R, Pecht I (2005) Biophys J 89:2121-2133.
25. Pecht I, Gakamsky DM (2005) FEBS Lett 579:3336-3341.
26. Davis DM, Reyburn HT, Pazmany L, Chiu I, Mandelboim O, Strominger JL (1997) Eur J Immunol 27:2714-2719.
27. Trautmann L, Rimbert M, Echasserieau K, Saulquin X, Neveu B, Dechanet J, Cerundolo V, Bonneville M (2005) J Immunol 175:6123-6132.