A receptor-binding-based bioassay to determine the potency of a plasmid biopharmaceutical encoding VEGF-C

Analytical and Bioanalytical Chemistry

Volumn 389, Issue 7-8, 2007, Pages 2109-2113

  Waerner, Thomas ^a   Girsch, Thomas ^a   Varga, Sandra ^a   Huang, Lichun ^b,c   Gornikiewicz, Alexander ^a   Loeber, Gerhard ^a  

^a BOEHRINGER INGELHEIM RCV GMBH AND CO KG   (Austria)

^b Corautus Genetics Inc ^*  (United States)

^c CELL GENESYS INC   (United States)

Author keywords

Bioanalytical methods; Bioassays; Biotechnological products; ELISA; Immunoassays; Pharmaceuticals; Quality assurance control

Indexed keywords

BIOACTIVITY; CELL CULTURE; DRUG PRODUCTS; PROTEINS; QUALITY ASSURANCE;

BIOANALYTICAL METHODS; BIOTECHNOLOGICAL PRODUCTS; ELISA; IMMUNOASSAYS;

BIOASSAY;

DRUG; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 3;

ARTICLE; BIOASSAY; DRUG DESIGN; GENE VECTOR; GENETICS; IC 50; METABOLISM; METHODOLOGY; PLASMID; QUALITY CONTROL; REPRODUCIBILITY; STANDARD; TIME; VALIDATION STUDY;

BIOLOGICAL ASSAY; DRUG DESIGN; GENETIC VECTORS; INHIBITORY CONCENTRATION 50; PHARMACEUTICAL PREPARATIONS; PLASMIDS; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR C; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3;

MAMMALIA;

EID: 36649027681     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-007-1662-8     Document Type: Article

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