메뉴 건너뛰기




Volumn 105, Issue 3, 2003, Pages 205-213

Production of supercoiled multimeric plasmid DNA for biopharmaceutical application

Author keywords

Biopharmaceutical; Concatemer; Cultivation; Gene therapy; Genetic vaccination; Plasmid

Indexed keywords

DIMERS; DNA; DRUG PRODUCTS; ESCHERICHIA COLI; MONOMERS;

EID: 0142169017     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2003.07.004     Document Type: Article
Times cited : (30)

References (15)
  • 1
    • 0018800089 scopus 로고
    • A rapid alkaline extraction procedure for screening recombinant plasmid DNA
    • Birnboim H.C., Doly J. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucl. Acids Res. 7:1979;1513-1523.
    • (1979) Nucl. Acids Res. , vol.7 , pp. 1513-1523
    • Birnboim, H.C.1    Doly, J.2
  • 2
    • 0037078985 scopus 로고    scopus 로고
    • Gene therapy: A tragic setback
    • Check E. Gene therapy: a tragic setback. Nature. 420:2002;116-118.
    • (2002) Nature , vol.420 , pp. 116-118
    • Check, E.1
  • 3
    • 0028000241 scopus 로고
    • Direct gene transfer into muscle
    • Danko I., Wolff J.A. Direct gene transfer into muscle. Vaccine. 12:1994;1499-1502.
    • (1994) Vaccine , vol.12 , pp. 1499-1502
    • Danko, I.1    Wolff, J.A.2
  • 4
    • 0030738441 scopus 로고    scopus 로고
    • Transcription from plasmid expression vectors is increased up to 14-fold when plasmids are transfected as concatemers
    • Leahy P., Carmichael G.G., Rossomando E.F. Transcription from plasmid expression vectors is increased up to 14-fold when plasmids are transfected as concatemers. Nucl. Acids Res. 25:1997;449-450.
    • (1997) Nucl. Acids Res. , vol.25 , pp. 449-450
    • Leahy, P.1    Carmichael, G.G.2    Rossomando, E.F.3
  • 5
    • 0037419671 scopus 로고    scopus 로고
    • Supercoiled plasmid DNA: Selective purification by thiophilic/aromatic adsorption
    • Lemmens R., Olsson U., Nyhammar T., Stadler J. Supercoiled plasmid DNA: selective purification by thiophilic/aromatic adsorption. J. Chromatogr. B. 784:2003;291-300.
    • (2003) J. Chromatogr. B , vol.784 , pp. 291-300
    • Lemmens, R.1    Olsson, U.2    Nyhammar, T.3    Stadler, J.4
  • 6
    • 0034159940 scopus 로고    scopus 로고
    • Gene therapy: The first decade
    • Mountain A. Gene therapy: the first decade. Trends Biotechnol. 18:2000;119-128.
    • (2000) Trends Biotechnol. , vol.18 , pp. 119-128
    • Mountain, A.1
  • 7
    • 0033120652 scopus 로고    scopus 로고
    • Large-scale production of pharmaceutical-grade plasmid DNA for gene therapy: Problems and bottlenecks
    • Prazeres D.M.F., Ferreira G.N.M., Monteiro G.A., Cooney C.L., Cabral J.M.S. Large-scale production of pharmaceutical-grade plasmid DNA for gene therapy: problems and bottlenecks. Trends Biotechnol. 17:1999;169-174.
    • (1999) Trends Biotechnol. , vol.17 , pp. 169-174
    • Prazeres, D.M.F.1    Ferreira, G.N.M.2    Monteiro, G.A.3    Cooney, C.L.4    Cabral, J.M.S.5
  • 12
    • 0030595040 scopus 로고    scopus 로고
    • Rapid determination of plasmid copy number
    • Schmidt T., Friehs K., Flaschel E. Rapid determination of plasmid copy number. J. Biotechnol. 49:1996;219-229.
    • (1996) J. Biotechnol. , vol.49 , pp. 219-229
    • Schmidt, T.1    Friehs, K.2    Flaschel, E.3
  • 13
    • 0033570005 scopus 로고    scopus 로고
    • Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis
    • Schmidt T., Friehs K., Schleef M., Voβ C., Flaschel E. Quantitative analysis of plasmid forms by agarose and capillary gel electrophoresis. Anal. Biochem. 274:1999a;235-240.
    • (1999) Anal. Biochem. , vol.274 , pp. 235-240
    • Schmidt, T.1    Friehs, K.2    Schleef, M.3    Voß, C.4    Flaschel, E.5
  • 14
    • 0142255934 scopus 로고    scopus 로고
    • Hochzelldichtefermentation zur Gewinnung von Plasmid-DNA für Gentherapie und genetische Impfung
    • Schmidt T., Schleef M., Friehs K., Flaschel E. Hochzelldichtefermentation zur Gewinnung von Plasmid-DNA für Gentherapie und genetische Impfung. Bioforum. 22:1999b;174-177.
    • (1999) Bioforum , vol.22 , pp. 174-177
    • Schmidt, T.1    Schleef, M.2    Friehs, K.3    Flaschel, E.4
  • 15
    • 0004176891 scopus 로고    scopus 로고
    • Blackwell Scientific Publications, Oxford
    • Summers, D.K., 1996. The Biology of Plasmids. Blackwell Scientific Publications, Oxford.
    • (1996) The Biology of Plasmids
    • Summers, D.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.