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As our work was under completion, a patent from DuPont (WO, 113491, 2005) appeared in the literature that presented the synthesis of compound 2c; however, the reported synthesis is less efficient than ours because the potassium salt of the thiolate was isolated and needed to be carefully dried, and because 2c was apparently obtained in a crude 88.5% yield. Our approach does not need to isolate the thiolate, and our isolated yield is higher.
-
As our work was under completion, a patent from DuPont (WO, 113491, 2005) appeared in the literature that presented the synthesis of compound 2c; however, the reported synthesis is less efficient than ours because the potassium salt of the thiolate was isolated and needed to be carefully dried, and because 2c was apparently obtained in a crude 88.5% yield. Our approach does not need to isolate the thiolate, and our isolated yield is higher.
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Similar sulfonyl chlorides are claimed in a patent from Daikin Industries, Ltd, see ref 23, However, no ArSCF2SO2Cl was exemplified
-
2Cl was exemplified.
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36649015733
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2Br) as precursor which has to be isolated, transformed into the sulfonyl chloride, and then transformed into the corresponding sulfonyl fluoride through an halogene exchange reaction. Our approach is more general, much simpler and is carried out in the same pot.
-
2Br) as precursor which has to be isolated, transformed into the sulfonyl chloride, and then transformed into the corresponding sulfonyl fluoride through an halogene exchange reaction. Our approach is more general, much simpler and is carried out in the same pot.
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