Pharmacokinetics of recombinant human growth hormone administered by cool.click™ 2, a new needle-free device, compared with subcutaneous administration using a conventional syringe and needle

BMC Clinical Pharmacology

Volumn 7, Issue , 2007, Pages

  Brearley, Chris ^a   Priestley, Anthony ^b   Leighton Scott, James ^b   Christen, Michel ^a  

^a Serono International SA   (Switzerland)

^b LCG Bioscience   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN GROWTH HORMONE; RECOMBINANT GROWTH HORMONE; SOMATOSTATIN; RECOMBINANT PROTEIN;

ADULT; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; CLINICAL TRIAL; CONFIDENCE INTERVAL; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; FRIEDMAN TEST; HEADACHE; HUMAN; HUMAN EXPERIMENT; INTERMETHOD COMPARISON; MALE; MAXIMUM PLASMA CONCENTRATION; MEDICAL INSTRUMENTATION; NAUSEA; NEEDLE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; TIME TO MAXIMUM PLASMA CONCENTRATION; TREATMENT OUTCOME; BIOAVAILABILITY; BIOLOGICAL MODEL; BLOOD; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; EQUIPMENT DESIGN; INSTRUMENTATION; JET INJECTION; PATIENT COMPLIANCE; PHARMACOKINETICS; PHASE 1 CLINICAL TRIAL; SUBCUTANEOUS DRUG ADMINISTRATION; SYRINGE;

ADULT; BIOLOGICAL AVAILABILITY; CROSS-OVER STUDIES; EQUIPMENT DESIGN; HUMAN GROWTH HORMONE; HUMANS; INJECTIONS, JET; INJECTIONS, SUBCUTANEOUS; MALE; MODELS, BIOLOGICAL; NEEDLES; PATIENT COMPLIANCE; RECOMBINANT PROTEINS; SYRINGES; THERAPEUTIC EQUIVALENCY;

EID: 36549084177     PISSN: None     EISSN: 14726904     Source Type: Journal    
DOI: 10.1186/1472-6904-7-10     Document Type: Article

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