A steroid fraction of chloroform extract from bee pollen of Brassica campestris induces apoptosis in human prostate cancer PC-3 cells

Phytotherapy Research

Volumn 21, Issue 11, 2007, Pages 1087-1091

  Wu, Yao Dong ^a   Lou, Yi Jia ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Apoptosis; Brassica campestris L.; Prostate cancer

Indexed keywords

BRASSICA EXTRACT; CASPASE 3; CHLOROFORM; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELL VIABILITY; CHINESE CABBAGE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; MALE; POLLEN; PROSTATE CANCER; PROTEIN EXPRESSION; WESTERN BLOTTING;

ADENOCARCINOMA; ANIMALS; APOPTOSIS; BEES; BLOTTING, WESTERN; BRASSICA; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CHLOROFORM; FLOW CYTOMETRY; HELA CELLS; HUMANS; MALE; MICROSCOPY, FLUORESCENCE; PLANT EXTRACTS; POLLEN; PROSTATIC NEOPLASMS; STEROIDS;

APOIDEA; BRASSICA RAPA;

EID: 36549074115     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2235     Document Type: Article

References (12)

1. Aliyazicioglu Y, Deger O, Ovali E et al. 2005. Effects of Turkish pollen and propolis extracts on respiratory burst for K-562 cell lines. Int Immunopharmacol 5: 1652-1657.
2. Gong WG. 1991. Fuzheng Quxie effects of bee pollen of Brassica campestris L. Zhejiang Zhong Yi Za Zhi 11: 513-514.
3. Huang A, Gandour-Edwards R, Rosenthal SA, Siders DB, Deitch AD, White RW. 1998. p53 and bcl-2 immunohistochemical alterations in prostate cancer treated with radiation therapy. Urology 51: 346-351.
4. Kaighn ME, Lechner JF, Narayan KS, Jones LW. 1978. Prostate carcinoma: tissue culture cell lines. Natl Cancer Inst Monogr 49: 17-21.
5. Kothakota S, Azuma T, Reinhard C et al. 1997. Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 278: 294-298.
6. Krajewska M, Krajewski S, Epstein JI et al. 1996. Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. Am J Pathol 148: 1567-1576.
7. McDonnell TJ, Troncoso P, Brisbay SM et al. 1992. Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Cancer Res 52: 6940-6944.
8. Petrylak DP. 2005. Chemotherapy for androgen-independent prostate cancer. World J Urol 23: 10-13.
9. Raffo AJ, Perlman H, Chen MW, Day ML, Streitman JS, Buttyan R. 1995. Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo. Cancer Res 55: 4438-4445.
10. Ren YH, Liu YP. 2001. The application of bee pollen as a natural food for human health. Shi Pin Yan Jiu Yu Kai Fa 4: 44-49.
11. van Bokhoven A, Varella-Garcia M, Korch C et al. 2003. Molecular characterization of human prostate carcinoma cell lines. Prostate 57: 205-225.
12. Yang XP, Wu MC. 2006. Study on the antitumor effect of rape bee-pollen polysaccharide in tumor bearing mice. Acta Nutr Sin 28: 160-162.