Squamous Cell Carcinoma Antigen Correlates with Tumor Burden but Lacks Prognostic Potential for Occult Lymph Node Metastases in Penile Cancer

Urology

Volumn 70, Issue 5, 2007, Pages 975-979

  Hungerhuber, Edwin ^a,b   Schlenker, Boris ^b   Schneede, Peter ^a   Stief, Christian G ^a   Karl, Alexander ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b Penile Cancer Working Group   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR ANTIGEN;

ADULT; ARTICLE; CANCER CONTROL; CANCER EPIDEMIOLOGY; CANCER GROWTH; CONTROLLED STUDY; DISEASE SEVERITY; HUMAN; LYMPH NODE METASTASIS; MALE; MEASUREMENT; PENIS CANCER; PRIORITY JOURNAL; PROGNOSIS; SQUAMOUS CELL CARCINOMA; TUMOR VOLUME;

ANTIGENS, NEOPLASM; CARCINOMA, SQUAMOUS CELL; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; PENILE NEOPLASMS; PROGNOSIS; SERPINS;

EID: 36549057080     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2007.07.013     Document Type: Article

References (21)

1. Horenblas S., van Tinteren H., Delemarre J.F., et al. Squamous cell carcinoma of the penis: accuracy of tumor, nodes and metastasis classification system, and role of lymphangiography, computerized tomography scan and fine needle aspiration cytology. J Urol 146 (1991) 1279-1283
2. McDougal W.S., Kirchner Jr. F.K., Edwards R.H., et al. Treatment of carcinoma of the penis: the case for primary lymphadenectomy. J Urol 136 (1986) 38-41
3. Solsona E., Iborra I., Rubio J., et al. Prospective validation of the association of local tumor stage and grade as a predictive factor for occult lymph node micrometastasis in patients with penile carcinoma and clinically negative inguinal lymph nodes. J Urol 165 (2001) 1506-1509
4. Kato H., and Torigoe T. Radioimmunoassay for tumor antigen of human cervical squamous cell carcinoma. Cancer 40 (1977) 1621-1628
5. Senekjian E.K., Young J.M., Weiser P.A., et al. An evaluation of squamous cell carcinoma antigen in patients with cervical squamous cell carcinoma. Am J Obstet Gynecol 157 (1987) 433-439
6. Fuith L.C., and Daxenbichler G. Squamous cell carcinoma antigen in patients with cancer of the uterine cervix. Gynecol Obstet Invest 26 (1988) 77-82
7. Mino N., Iio A., and Hamamoto K. Availability of tumor-antigen 4 as a marker of squamous cell carcinoma of the lung and other organs. Cancer 62 (1988) 730-734
8. Crombach G., Scharl A., Vierbuchen M., et al. Detection of squamous cell carcinoma antigen in normal squamous epithelia and in squamous cell carcinomas of the uterine cervix. Cancer 63 (1989) 1337-1342
9. Bolli J.A., Doering D.L., Bosscher J.R., et al. Squamous cell carcinoma antigen: clinical utility in squamous cell carcinoma of the uterine cervix. Gynecol Oncol 55 (1994) 169-173
10. Ngan H.Y., Cheng G.T., Yeung W.S., et al. The prognostic value of TPA and SCC in squamous cell carcinoma of the cervix. Gynecol Oncol 52 (1994) 63-68
11. Wishnow K.I., Johnson D.E., and Fritsche H. Squamous cell carcinoma antigen (TA-4) in penile carcinoma. Urology 36 (1990) 315-317
12. Takahashi Y., Horie M., Isogai K., et al. [Clinical study of serum squamous cell carcinoma-related antigen levels in penile cancer. ] Hinyokika Kiyo 33 (1987) 396-399
13. Horenblas S. Lymphadenectomy for squamous cell carcinoma of the penis. Part 2: the role and technique of lymph node dissection. BJU Int 88 (2001) 473-483
14. Horenblas S. Lymphadenectomy for squamous cell carcinoma of the penis. Part 1: diagnosis of lymph node metastasis. BJU Int 88 (2001) 467-472
15. Bouchot O., Rigaud J., Maillet F., et al. Morbidity of inguinal lymphadenectomy for invasive penile carcinoma. Eur Urol 45 (2004) 761-765
16. Persky L., and deKernion J. Carcinoma of the penis. CA Cancer J Clin 36 (1986) 258-273
17. Hungerhuber E., Schlenker B., Karl A., et al. Risk stratification in penile carcinoma: 25-year experience with surgical inguinal lymph node staging. Urology 68 (2006) 621-625
18. Laniado M.E., Lowdell C., Mitchell H., et al. Squamous cell carcinoma antigen: a role in the early identification of nodal metastases in men with squamous cell carcinoma of the penis. BJU Int 92 (2003) 248-250
19. Horenblas S., Jansen L., Meinhardt W., et al. Detection of occult metastasis in squamous cell carcinoma of the penis using a dynamic sentinel node procedure. J Urol 163 (2000) 100-104
20. Kroon B.K., Valdes O.R., Nieweg O.E., et al. Non-visualization of sentinel lymph nodes in penile carcinoma. Eur J Nucl Med Mol Imaging 32 (2005) 1096-1099
21. Hungerhuber E., Frimberger D., Karl A., et al. Patients with penile cancer and palpable inguinal lymph nodes should not be staged by dynamic sentinel lymph node biopsy. Eur Urol Suppl 3 (2004) 188