-
2
-
-
0141642224
-
The NIH Roadmap
-
Zerhouni E. The NIH Roadmap. Science 2003; 302: 63-72
-
(2003)
Science
, vol.302
, pp. 63-72
-
-
Zerhouni, E.1
-
3
-
-
26444505936
-
Translational and clinical science - time for a new vision
-
Zerhouni E. Translational and clinical science - time for a new vision. NEJM 2005; 353: 1621-3
-
(2005)
NEJM
, vol.353
, pp. 1621-1623
-
-
Zerhouni, E.1
-
4
-
-
25644443164
-
-
Fischer A, Borensztein P, Roussel C. The Europen rare disease thertapeutic initiative. A PPP is promoting research on new treatments for rare diseases. PLoS Medicine 2005; 2: e243
-
Fischer A, Borensztein P, Roussel C. The Europen rare disease thertapeutic initiative. A PPP is promoting research on new treatments for rare diseases. PLoS Medicine 2005; 2: e243
-
-
-
-
5
-
-
27644484069
-
PPPs succeeding in tackling neglected diseases
-
Frantz S. PPPs succeeding in tackling neglected diseases. Nature Rev Drug Discov 2005; 4: 796
-
(2005)
Nature Rev Drug Discov
, vol.4
, pp. 796
-
-
Frantz, S.1
-
6
-
-
4544321119
-
Cutting the cost of drug development ?
-
Rawlins MD. Cutting the cost of drug development ? Nature Rev Drug Discov 2004; 3: 360-4
-
(2004)
Nature Rev Drug Discov
, vol.3
, pp. 360-364
-
-
Rawlins, M.D.1
-
7
-
-
30444449389
-
Reform of drug regulation - beyond an independent drug-safety board
-
Ray WA, Stein CM. Reform of drug regulation - beyond an independent drug-safety board. NEJM 2006; 354: 194-200
-
(2006)
NEJM
, vol.354
, pp. 194-200
-
-
Ray, W.A.1
Stein, C.M.2
-
8
-
-
84888705279
-
-
http://www.medichildren.net/
-
-
-
-
9
-
-
33645231285
-
European Technology Platform on Innovative Medicines
-
Donnelly F, Jehenson P. European Technology Platform on Innovative Medicines. Int J Pharm Med 2005; 19: 153-61
-
(2005)
Int J Pharm Med
, vol.19
, pp. 153-161
-
-
Donnelly, F.1
Jehenson, P.2
-
10
-
-
84888724027
-
-
SRA on http://europa.eu.int/comm/research/fp6/index_en.cfm?p=1_innomed
-
SRA on http://europa.eu.int/comm/research/fp6/index_en.cfm?p=1_innomed
-
-
-
-
11
-
-
84888689725
-
-
http://www.agence-nationale-recherche.fr
-
-
-
-
12
-
-
24344508547
-
Regulating acaademic-industrial research relationships - solving problems or stifling progress ?
-
Stossel TP. Regulating acaademic-industrial research relationships - solving problems or stifling progress ? NEJM 2005; 353: 1060-5
-
(2005)
NEJM
, vol.353
, pp. 1060-1065
-
-
Stossel, T.P.1
-
13
-
-
84888697918
-
-
http://www.orphanxchange.org/
-
-
-
-
14
-
-
84888681483
-
-
http://www.pactepourlarecherche.fr/presse/2005/aaccarnot.pdf
-
-
-
-
15
-
-
84888738892
-
-
http://www.competitivite.gouv.fr
-
-
-
-
16
-
-
4344645978
-
Can the pharmaceutical industry reduce attrition rates ?
-
Kola I, Landis J. Can the pharmaceutical industry reduce attrition rates ? Nature Rev Drug Discov 2004; 3: 711-5
-
(2004)
Nature Rev Drug Discov
, vol.3
, pp. 711-715
-
-
Kola, I.1
Landis, J.2
-
17
-
-
2642570856
-
Methods for targeting biologicals to specific disease sites
-
Nissim A. Gofur Y, Vesselier S et al. Methods for targeting biologicals to specific disease sites. Trends Mol Med 2004; 10: 269-74
-
(2004)
Trends Mol Med
, vol.10
, pp. 269-274
-
-
Nissim, A.1
Gofur, Y.2
Vesselier, S.3
-
18
-
-
25644454404
-
A new grammar for drug discovery
-
Fishman MC, Porter JA. A new grammar for drug discovery. Nature 2005; 437: 491-3
-
(2005)
Nature
, vol.437
, pp. 491-493
-
-
Fishman, M.C.1
Porter, J.A.2
-
19
-
-
18844414553
-
Personalized medicine prompts push to redisgn clinical trials. Editorial
-
Singer E. Personalized medicine prompts push to redisgn clinical trials. Editorial, Nature Med 2005; 11: 462
-
(2005)
Nature Med
, vol.11
, pp. 462
-
-
Singer, E.1
-
20
-
-
30944449815
-
-
The Royal Society, September, Access through
-
The Royal Society. Personalised medicines hopes and reality. September 2005, pp 1-52. Access through http://www.royalsoc.ac.uk/document.asp?id=3780
-
(2005)
Personalised medicines hopes and reality
, pp. 1-52
-
-
-
21
-
-
19944434066
-
EUFEPS report : Contribution of academic research to discovery and development of medicines : current status and future opportunities
-
Couvreur P et al. EUFEPS report : contribution of academic research to discovery and development of medicines : current status and future opportunities. Eur J Pharm Sci 2005; 24: 245-52
-
(2005)
Eur J Pharm Sci
, vol.24
, pp. 245-252
-
-
Couvreur, P.1
-
22
-
-
84888665560
-
-
Marionnet AV. PME, innovations technologiques et secteurs d'application. Pharma-Biotech. OSEO-ANVAR. Direction Technologie Projets Européens, pp 1-43 (2004)
-
Marionnet AV. PME, innovations technologiques et secteurs d'application. Pharma-Biotech. OSEO-ANVAR. Direction Technologie Projets Européens, pp 1-43 (2004)
-
-
-
-
23
-
-
84888713078
-
-
http://www.eortc.be
-
-
-
-
24
-
-
84888666381
-
-
http://www.gereq.net
-
-
-
-
25
-
-
84888722195
-
-
http://www.orpha.net
-
-
-
-
26
-
-
11844251271
-
European Clinical Research Infrastructures Network : Promoting harmonisation and quality in European clinical research
-
Demotes-Mainard J, Ohmann C : European Clinical Research Infrastructures Network : promoting harmonisation and quality in European clinical research. Lancet 2005; 365: 107-108
-
(2005)
Lancet
, vol.365
, pp. 107-108
-
-
Demotes-Mainard, J.1
Ohmann, C.2
-
27
-
-
84888723086
-
-
Demotes-Mainard J. et al. How to exploit existing assets and resources in Europe ? Report of the stakeholders forum on 'How to establish a European Technology Platform for innovative medicines'. Barcelona, April 21-22 (2005)
-
Demotes-Mainard J. et al. How to exploit existing assets and resources in Europe ? Report of the stakeholders forum on 'How to establish a European Technology Platform for innovative medicines'. Barcelona, April 21-22 (2005)
-
-
-
-
28
-
-
84888756088
-
-
LEEM/AD Little. Optimisation de l'attractivité de la France pour la production biologique. Comité Biotechnologie du Leem, 28 novembre 2005
-
LEEM/AD Little. Optimisation de l'attractivité de la France pour la production biologique. Comité Biotechnologie du Leem, 28 novembre 2005
-
-
-
-
29
-
-
18244368977
-
Clinical research infras tructures and networks in France : Report on the trench ECRIN workshop
-
Demotes-Mainard J, Chêne G, Libersa C, Pignon JP : Clinical research infras tructures and networks in France : report on the trench ECRIN workshop. Thérapie 2005; 60: 183-99
-
(2005)
Thérapie
, vol.60
, pp. 183-199
-
-
Demotes-Mainard, J.1
Chêne, G.2
Libersa, C.3
Pignon, J.P.4
-
30
-
-
29144490834
-
-
Clément B, Grimaud JA, Deleuze JF, Postaire E. Le réseau des Centres de Ressources Biologiques Humains. Une infrastructure essentielle pour la recherche biomédicale en Europe. Thérapie 2005; 60: 351-4
-
Clément B, Grimaud JA, Deleuze JF, Postaire E. Le réseau des Centres de Ressources Biologiques Humains. Une infrastructure essentielle pour la recherche biomédicale en Europe. Thérapie 2005; 60: 351-4
-
-
-
-
31
-
-
27644555675
-
Anticipating change in drug development : The emerging era of translational medicine and therapeutics
-
Fitzgerald GA. Anticipating change in drug development : the emerging era of translational medicine and therapeutics. Nature Rev Drug Discov 2005; 4: 815-8
-
(2005)
Nature Rev Drug Discov
, vol.4
, pp. 815-818
-
-
Fitzgerald, G.A.1
-
32
-
-
31344473996
-
The value of phase 4 clinical testing
-
Vlahakes GJ. The value of phase 4 clinical testing. NEJM 2006; 354: 413-5
-
(2006)
NEJM
, vol.354
, pp. 413-415
-
-
Vlahakes, G.J.1
-
33
-
-
7644228634
-
Independent clinical research in Europe
-
Remuzzi G, Schieppati A, Boissel JP, Garattini S, Horton R: Independent clinical research in Europe. Lancet 2004; 364: 17232-6
-
(2004)
Lancet
, vol.364
, pp. 17232-17236
-
-
Remuzzi, G.1
Schieppati, A.2
Boissel, J.P.3
Garattini, S.4
Horton, R.5
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