Active Coxsackieviral B Infection Is Associated With Disruption of Dystrophin in Endomyocardial Tissue of Patients Who Died Suddenly of Acute Myocardial Infarction

Journal of the American College of Cardiology

Volumn 50, Issue 23, 2007, Pages 2207-2214

  Andréoletti, Laurent ^a   Ventéo, Lydie ^a   Douche Aourik, Fatima ^b   Canas, Frédéric ^a   de la Grandmaison, Geoffroy Lorin ^c   Jacques, Jérôme ^a   Moret, Hélène ^a   Jovenin, Nicolas ^a   Mosnier, Jean François ^d   Matta, Mathieu ^a   Duband, Sébastien ^b   Pluot, Michel ^a   Pozzetto, Bruno ^b   Bourlet, Thomas ^b  

^a REIMS UNIVERSITY HOSPITAL   (France)

^b UNIVERSITY HOSPITAL OF SAINT ETIENNE   (France)

^c RAYMOND POINCARÉ HOSPITAL   (France)

^d NANTES UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; CAPSID VIRAL PROTEIN 1; DYSTROPHIN; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS B; GENE IDENTIFICATION; GENE SEQUENCE; HEART INFARCTION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS INFECTION;

ADULT; AGED; AGED, 80 AND OVER; CAPSID PROTEINS; CASE-CONTROL STUDIES; DEATH, SUDDEN, CARDIAC; DYSTROPHIN; ENDOCARDIUM; ENTEROVIRUS B, HUMAN; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; RNA, VIRAL;

EID: 36448978241     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2007.07.080     Document Type: Article

References (31)

1. Boersma E., Mercado N., Poldermans D., Gardien M., Vos J., and Simoons M.L. Acute myocardial infarction. Lancet 361 (2003) 847-858
2. Epstein S.E., Zhou Y.F., and Zhu J. Infection and atherosclerosis: emerging mechanistic paradigms. Circulation 100 (1999) e20-e28
3. Leinonen M., and Saikku P. Infections and atherosclerosis. Scand Cardiovasc J 34 (2000) 12-20
4. Conaldi P.G., Serra C., Mossa A., et al. Persistent infection of human vascular endothelial cells by group B coxsackieviruses. J Infect Dis 175 (1997) 693-696
5. Sole M.J., and Liu P. Viral myocarditis: a paradigm for understanding the pathogenesis and treatment of dilated cardiomyopathy. J Am Coll Cardiol 22 (1993) 99A-105A
6. Badorff C., Lee G.H., Lamphear B.J., et al. Enteroviral protease 2A cleaves dystrophin: evidence of cytoskeletal disruption in an acquired cardiomyopathy. Nat Med 5 (1999) 320-326
7. Lee Y.T., Sung K., Shin J.-O., and Jeon E.S. Disruption of dystrophin in acute fulminant coxsackieviral B4 infection. Circulation 113 (2006) e76-e77
8. Badorff C., and Knowlton K.U. Dystrophin disruption in enterovirus-induced myocarditis and dilated cardiomyopathy: from bench to bedside. Med Microbiol Immunol 193 (2004) 121-126
9. Lau R.C. Coxsackie B virus-specific IgM responses in coronary care unit patients. J Med Virol 18 (1986) 193-198
10. Nicholls A.C., and Thomas M. Coxsackie virus infection in acute myocardial infarction. Lancet 1 (1977) 883-884
11. Roivainen M., Alfthan G., Jousilahti P., Kimpimaki M., Hovi T., and Tuomilehto J. Enterovirus infections as a possible risk factor for myocardial infarction. Circulation 98 (1998) 2534-2537
12. Woods J.D., Nimmo M.J., and Mackay-Scollay E.M. Acute transmural myocardial infarction associated with active coxsackie virus B infection. Am Heart J 89 (1975) 283-287
13. Griffiths P.D., Hannington G., and Booth J.C. Coxsackie B virus infections and myocardial infarction. Results from a prospective, epidemiologically controlled study. Lancet 1 (1980) 1387-1389
14. Andreoletti L., Bourlet T., Moukassa D., et al. Enteroviruses can persist with or without active viral replication in cardiac tissue of patients with end-stage ischemic or dilated cardiomyopathy. J Infect Dis 182 (2000) 1222-1227
15. Andreoletti L., Hober D., Decoene C., et al. Detection of enteroviral RNA by polymerase chain reaction in endomyocardial tissue of patients with chronic cardiac diseases. J Med Virol 48 (1996) 53-59
16. Calabrese F., Basso C., Valente M., and Thiene G. Coronary thrombosis and sudden death after an enteroviral infection. Case report. APMIS 111 (2003) 315-318
17. Kwon T.W., Kim do K., Ye J.S., et al. Detection of enterovirus, cytomegalovirus, and Chlamydia pneumoniae in atheromas. J Microbiol 42 (2004) 299-304
18. Alpert J.S., Thygesen K., Antman E., et al. Myocardial infarction redefined-a consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction. J Am Coll Cardiol 36 (2000) 959-969
19. Li Y., Bourlet T., Andreoletti L., et al. Enteroviral capsid protein VP1 is present in myocardial tissues from some patients with myocarditis or dilated cardiomyopathy. Circulation 101 (2000) 231-234
20. Zoll G.J., Melchers W.J., Kopecka H., Jambroes G., van der Poel H.J., and Galama J.M. General primer-mediated polymerase chain reaction for detection of enteroviruses: application for diagnostic routine and persistent infections. J Clin Microbiol 30 (1992) 160-165
21. Trabelsi A., Grattard F., Nejmeddine M., Aouni M., Bourlet T., and Pozzetto B. Evaluation of an enterovirus group-specific antiVP1 monoclonal antibody, 5-D8/1, in comparison with neutralization and PCR for rapid identification of enteroviruses in cell culture. J Clin Microbiol 33 (1995) 2454-2457
22. Sabattini E., Bisgaard K., Ascani S., et al. The EnVision system: a new immunohistochemical method for diagnostics and research. Critical comparison with the APAAP, ChemMate, CSA, LABC, and SABC techniques. J Clin Pathol 51 (1998) 506-511
23. Oberste M.S., Nix W.A., Maher K., and Pallansch M.A. Improved molecular identification of enteroviruses by RT-PCR and amplicon sequencing. J Clin Virol 26 (2003) 375-377
24. Rey L., Lambert V., Wattre P., and Andreoletti L. Detection of enteroviruses ribonucleic acid sequences in endomyocardial tissue from adult patients with chronic dilated cardiomyopathy by a rapid RT-PCR and hybridization assay. J Med Virol 64 (2001) 133-140
25. Douche-Aourik F., Bourlet T., Mosnier J.F., et al. Association between enterovirus endomyocardial infection and late severe cardiac events in some adult patients receiving heart transplants. J Med Virol 75 (2005) 47-53
26. Epstein S.E., and Zhu J. Lack of association of infectious agents with risk of future myocardial infarction and stroke: definitive evidence disproving the infection/coronary artery disease hypothesis?. Circulation 100 (1999) 1366-1368
27. Narula J., Khaw B.A., Dec Jr. G.W., et al. Brief report: recognition of acute myocarditis masquerading as acute myocardial infarction. N Engl J Med 328 (1993) 1714-1715
28. Dec W., Waldman H., Southern J., Fallon J.T., Hutter Jr. A.M., and Palacios I. Viral myocarditis mimicking acute myocardial infarction. J Am Coll Cardiol 21 (1993) 1302-1303
29. Zhang H., Li Y., Peng T., et al. Localization of enteroviral antigen in myocardium and other tissues from patients with heart muscle disease by an improved immunohistochemical technique. J Histochem Cytochem 48 (2000) 579-584
30. Vallbracht K.B., Schwimmbeck P.L., Kuhl U., Seeberg B., and Schultheiss H.P. Endothelium-dependent flow-mediated vasodilation of systemic arteries is impaired in patients with myocardial virus persistence. Circulation 110 (2004) 2938-2945
31. Badorff C., Fichtlscherer B., Rhoads R.E., et al. Nitric oxide inhibits dystrophin proteolysis by coxsackieviral protease 2A through S-nitrosylation: a protective mechanism against enteroviral cardiomyopathy. Circulation 102 (2000) 2276-2281