An artificial molecular chaperone: Poly-pseudo-rotaxane with an extensible axle

Journal of the American Chemical Society

Volumn 129, Issue 46, 2007, Pages 14452-14457

  Osaki, Motofumi ^a   Takashima, Yoshinori ^a   Yamaguchi, Hiroyasu ^a   Harada, Akira ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADAMANTANE; INSERTION REACTIONS; MOLECULAR CHAPERONES; POLYMER CHAINS; POLYMERIZATION ABILITY;

CONFORMATIONS; CYCLODEXTRINS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYMERIZATION; SOLID STATE REACTIONS; X RAY POWDER DIFFRACTION;

PROTEINS;

2,6 O DIMETHYL BETA CYCLODEXTRIN; ADAMANTANE; ALPHA CYCLODEXTRIN; BETA CYCLODEXTRIN; CHAPERONE; CYCLODEXTRIN; CYCLODEXTRIN DERIVATIVE; DELTA VALEROLACTONE; LACTONE DERIVATIVE; POLY(DELTA VALEROLACTONE); POLYMER; ROTAXANE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONFORMATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYMERIZATION; PROTEIN BINDING; SOLID STATE; X RAY DIFFRACTION;

CYCLODEXTRINS; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CHAPERONES; POLYMERS; ROTAXANES; X-RAY DIFFRACTION;

EID: 36448938334     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja075140o     Document Type: Article

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36. The mixture of β-CD and δ-VL gave 1 as reported in ref 29. The resulting polymer 1, which was washed with only water to remove free β-CD, was found to form poly-pseudo-rotaxane (β-CD⊃1) by powder X-ray diffraction analysis. This result indicates that 1 prepared from the mixture of β-CD and δ-VL forms the poly-pseudo-rotaxane structure during the polymerization.
37. To confirm the insertion of monomer between β-CD and the polymer chain, block-copolymerization was carried out by using β-butyrolactone (β-BL) and β-CD⊃1. Poly(β-BL) was inserted between the β-CD - polymer linkage (see Supporting Information).