Genes encoding putative biogenic amine receptors in the parasitic nematode Brugia malayi

Invertebrate Neuroscience

Volumn 7, Issue 4, 2007, Pages 227-244

  Smith, Katherine A ^a   Komuniecki, Richard W ^a   Ghedin, Elodie ^b,c   Spiro, David ^b   Gray, John ^a  

^a UNIVERSITY OF TOLEDO   (United States)

^b J CRAIG VENTER INSTITUTE   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Brugia malayi; Caenorhabditis briggsae; Caenorhabditis elegans; Dopamine; G protein coupling; Octopamine; Serotonin; Tyramine

Indexed keywords

BIOGENIC AMINE; DOPAMINE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; OCTOPAMINE; SEROTONIN; TYRAMINE;

AMINO ACID SEQUENCE; ARTICLE; BIOINFORMATICS; BRUGIA MALAYI; CAENORHABDITIS ELEGANS; GENE STRUCTURE; NEMATODE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE; PHYLOGENETIC TREE; PHYLOGENY; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BIOGENIC AMINES; BRUGIA MALAYI; CAENORHABDITIS ELEGANS; GENE LIBRARY; GENES, HELMINTH; GENOME, HELMINTH; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, BIOGENIC AMINE; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 36448935302     PISSN: 13542516     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10158-007-0058-y     Document Type: Article

References (69)

1. Alkema MJ, Hunter-Ensor M, Ringstad N, Horvitz HR (2005) Tyramine functions independently of octopamine in the Caenorhabditis elegans nervous system. Neuron 46:247-260
2. Altschul SF, Madden TL, Schaer AA, Zhang J, Zhang Z, Miller W, Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25:3389-3402
3. Anosike JC, Nwoke BE, Ajayi EG, Onwuliri CO, Okoro OU, Oku EE, Asor JE, Amajuoyi OU, Ikpeama CA, Ogbusu FI, Meribe CO (2005) Lymphatic filariasis among the Ezza people of Ebonyi State, eastern Nigeria. Ann Agric Environ Med 12:181-186
4. Backstrom JR, Chang MS, Chu H, Niswender CM, Sanders-Bush E (1999) Agonist-directed signaling of serotonin 5-HT2C receptors: differences between serotonin and lysergic acid diethylamide (LSD). Neuropsychopharmacology 21:77S-81S
5. Ballesteros JA, Shi L, Javitch JA (2001) Structural mimicry in G protein-coupled receptors: Implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors. Mol Pharmacol 60:1-19
6. Blaxter ML, De Ley P, Garey JR, Liu LX, Scheldeman P, Vierstraete A, Vanfleteren JR, Mackey LY, Dorris M, Frisse LM, Vida JT, Thomas WK (1998) A molecular evolutionary framework for the phylum Nematoda. Nature 392:71-75
7. Blaxter M, Aslett M, Guiliano D, Daub J (1999) Parasitic helminth genomics. Filarial Genome Project. Parasitology 118(Suppl):S39-S51
8. Blaxter M, Daub J, Guiliano D, Parkinson J, Whitton C (2002) The Brugia malayi genome project: expressed sequence tags and gene discovery. Trans R Soc Trop Med Hyg 96:7-17
9. Bouchard C, Ribeiro P, Dube F, Demers C, Anctil M (2004) Identification of a novel aminergic-like G protein-coupled receptor in the cnidarian Renilla koellikeri. Gene 341:67-75
10. Bouvier M, Moffett S, Loisel TP, Mouillac B, Hebert T, Chidiac P (1995) Palmitoylation of G-protein-coupled receptors: a dynamic modification with functional consequences. Biochem Soc Trans 23:116-120
11. Carre-Pierrat M, Baillie D, Johnsen R, Hyde R, Hart A, Granger L, Segalat L (2006) Characterization of the Caenorhabditis elegans G protein-coupled serotonin receptors. Invert Neurosci 6:189-205
12. Chanda PK, Minchin MC, Davis AR, Greenberg L, Reilly Y, McGregor WH, Bhat R, Lubeck MD, Mizutani S, Hung PP (1993) Identification of residues important for ligand binding to the human 5-hydroxytryptamine1A serotonin receptor. Mol Pharmacol 43:516-520
13. Chase DL, Pepper JS, Koelle MR (2004) Mechanism of extrasynaptic dopamine signaling in Caenorhabditis elegans. Nat Neurosci 7:1096-1103
14. Chatwin HM, Rudling JE, Patel D, Reale V, Evans PD (2003) Site-directed mutagenesis studies on the Drosophila octopamine/tyramine receptor. Insect Biochem Mol Biol 33:173-184
15. Collins S (1993) Recent perspectives on the molecular structure and regulation of the beta 2-adrenoceptor. Life Sci 52:2083-2091
16. de Silva N, Guyatt H, Bundy D (1997) Anthelmintics. A comparative review of their clinical pharmacology. Drugs 53:769-788
17. Elmhurst JL, Xie Z, O'Dowd BF, George SR (2000) The splice variant D3nf reduces ligand binding to the D3 dopamine receptor: evidence for heterooligomerization. Brain Res Mol Brain Res 80:63-74
18. Fishburn CS, Belleli D, David C, Carmon S, Fuchs S (1993) A novel short isoform of the D3 dopamine receptor generated by alternative splicing in the third cytoplasmic loop. J Biol Chem 268:5872-5878
19. Flanagan CA (2005) A GPCR that is not "DRY". Mol Pharmacol 68:1-3
20. Gerhardt CC, Bakker RA, Piek GJ, Planta RJ, Vreugdenhil E, Leysen JE, Van Heerikhuizen H (1997) Molecular cloning and pharmacological characterization of a molluscan octopamine receptor. Mol Pharmacol 51:293-300
21. Ghedin E, Wang S, Foster JM, Slatko BE (2004) First sequenced genome of a parasitic nematode. Trends Parasitol 20:151-153
22. Ghedin E, Wang S, Spiro D, Caler E, Zhao Q, Crabtree J, Allen JE, Delcher AL, Guiliano DB, Miranda-Saavedra D, Angiuoli SV, Creasy T, Amedeo P, Haas B, El-Sayed NM, Wortman JR, Feldblyum T, Tallon L, Schatz M, Shumway M, Koo H, Salzberg SL, Schobel S, Pertea M, Pop M, White O, Barton GJ, Carlow CKS, Crawford MJ, Daub J, Dimmic MW, Estes CF, Foster JM, Ganatra M, Gregory WF, Johnson NM, Jin J, Komuniecki R, Korf I, Kumar S, Laney S, Li B-W, Li W, Lindblom TH, Lustigman S, Ma D, Maina CV, Martin DMA, McCarter JP, McReynolds L, Mitreva M, Nutman TB, Parkinson J, Peregrín-Alvarez JM, Poole C, Ren Q, Saunders L, Sluder AE, Smith K, Stanke M, Unnasch TR, Ware J, Wei AD, Weil G, Williams DJ, Zhang Y, Williams SA, Fraser-Liggett C, Slatko B, Blaxter ML, nd Scott AL (2007) Draft genome of the filarial nematode parasite Brugia malayi. Science 317:1756-1760
23. Goff SA, Ricke D, Lan TH, Presting G, Wang R, Dunn M, Glazebrook J, Sessions A, Oeller P, Varma H, Hadley D, Hutchison D, Martin C, Katagiri F, Lange BM, Moughamer T, Xia Y, Budworth P, Zhong J, Miguel T, Paszkowski U, Zhang S, Colbert M, Sun WL, Chen L, Cooper B, Park S, Wood TC, Mao L, Quail P, Wing R, Dean R, Yu Y, Zharkikh A, Shen R, Sahasrabudhe S, Thomas A, Cannings R, Gutin A, Pruss D, Reid J, Tavtigian S, Mitchell J, Eldredge G, Scholl T, Miller RM, Bhatnagar S, Adey N, Rubano T, Tusneem N, Robinson R, Feldhaus J, Macalma T, Oliphant A, Briggs S (2002) A draft sequence of the rice genome (Oryza sativa L. ssp. japonica). Science 296:92-100
24. Gomez-Escobar N, Lewis E, Maizels RM (1998) A novel member of the transforming growth factor-beta (TGF-beta) superfamily from the filarial nematodes Brugia malayi and B. pahangi. Exp Parasitol 88:200-209
25. Guiliano DB, Hall N, Jones SJ, Clark LN, Corton CH, Barrell BG, Blaxter ML (2002) Conservation of long-range synteny and microsynteny between the genomes of two distantly related nematodes. Genome Biol. 3: research0057.0051- research0057.0014
26. Hamdan FF, Ungrin MD, Abramovitz M, Ribeiro P (1999) Characterization of a novel serotonin receptor from Caenorhabditis elegans: cloning and expression of two splice variants. J Neurochem 72:1372-1383
27. Hobson RJ, Geng J, Gray AD, Komuniecki RW (2003) SER-7b, a constitutively active Galphas coupled 5-HT7-like receptor expressed in the Caenorhabditis elegans M4 pharyngeal motorneuron. J Neurochem 87:22-29
28. Hoerauf A (2006) New strategies to combat filariasis. Expert Rev Anti Infect Ther 4:211-222
29. Hofmann K, Stoffel W (1993) Tmbase-a database of membrane spanning proteins segments. Biol Chem Hoppe Seyler 374:166
30. Johnson MS, Robertson DN, Holland PJ, Lutz EM, Mitchell R (2006) Role of the conserved NPxxY motif of the 5-HT2A receptor in determining selective interaction with isoforms of ADP-ribosylation factor (ARF). Cell Signal 18:1793-1800
31. Karpa KD, Lin R, Kabbani N, Levenson R (2000) The dopamine D3 receptor interacts with itself and the truncated D3 splice variant d3nf: D3-D3nf interaction causes mislocalization of D3 receptors. Mol Pharmacol 58:677-683
32. Kroeze WK, Kristiansen K, Roth BL (2002) Molecular biology of serotonin receptors structure and function at the molecular level. Curr Top Med Chem 2:507-528
33. Lee KZ, Eizinger A, Nandakumar R, Schuster SC, Sommer RJ (2003a) Limited microsynteny between the genomes of Pristionchus pacificus and Caenorhabditis elegans. Nucleic Acids Res 31:2553-2560
34. Lee SP, O'Dowd BF, Rajaram RD, Nguyen T, George SR (2003b) D2 dopamine receptor homodimerization is mediated by multiple sites of interaction, including an intermolecular interaction involving transmembrane domain 4. Biochemistry 42:11023-11031
35. Liu K, Bergson C, Levenson R, Schmauss C (1994) On the origin of mRNA encoding the truncated dopamine D3-type receptor D3nf and detection of D3nf-like immunoreactivity in human brain. J Biol Chem 269:29220-29226
36. Livingstone CD, Strange PG, Naylor LH (1992) Molecular modelling of D2-like dopamine receptors. Biochem J 287(Pt 1):277-282
37. Martin GR, Humphrey PP (1994) Receptors for 5-hydroxytryptamine: current perspectives on classification and nomenclature. Neuropharmacology 33:261-273
38. Meldal BHM, Debenham NJ, De Ley P, De Ley IT, Vanfleteren JR, Vierstraete AR, Bert W, Borgonie G, Moens T, Tyler PA, Austen MC, Blaxter ML, Rogers AD, Lambshead PJD (2007) An improved molecular phylogeny of the Nematoda with special emphasis on marine taxa. Mol Phylogenet Evol 42:622-636
39. Molyneux D (2003) Lymphatic filariasis (elephantiasis) elimination: a public health success and development opportunity. Filaria J 2:13
40. Murray J, Manoury B, Balic A, Watts C, Maizels RM (2005) Bm-CPI-2, a cystatin from Brugia malayi nematode parasites, differs from Caenorhabditis elegans cystatins in a specific site mediating inhibition of the antigen-processing enzyme AEP. Mol Biochem Parasitol 139:197-203
41. Niacaris T, Avery L (2003) Serotonin regulates repolarization of the C. elegans pharyngeal muscle. J Exp Biol 206:223-231
42. Nimchinsky EA, Hof PR, Janssen WG, Morrison JH, Schmauss C (1997) Expression of dopamine D3 receptor dimers and tetramers in brain and in transfected cells. J Biol Chem 272:29229-29237
43. O'Halloran DM, Fitzpatrick DA, McCormack GP, McInerney JO, Burnell AM (2006) The molecular phylogeny of a nematode-specific clade of heterotrimeric G-protein alpha-subunit genes. J Mol Evol 63:87-94
44. Olde B, McCombie WR (1997) Molecular cloning and functional expression of a serotonin receptor from Caenorhabditis elegans. J Mol Neurosci 8:53-62
45. Parkinson J, Mitreva M, Hall N, Blaxter M, McCarter JP (2003) 400,000 nematode ESTs on the Net. Trends Parasitol 19:283-286
46. Peroutka SJ, Howell TA (1994) The molecular evolution of G protein-coupled receptors: focus on 5-hydroxytryptamine receptors. Neuropharmacology 33:319-324
47. Pollock NJ, Manelli AM, Hutchins CW, Steffey ME, MacKenzie RG, Frail DE (1992) Serine mutations in transmembrane V of the dopamine D1 receptor affect ligand interactions and receptor activation. J Biol Chem 267:17780-17786
48. Rex E, Komuniecki RW (2002) Characterization of a tyramine receptor from Caenorhabditis elegans. J Neurochem 82:1352-1359
49. Rex E, Hapiak V, Hobson R, Smith K, Xiao H, Komuniecki R (2005) TYRA-2 (F01E11.5): a Caenorhabditis elegans tyramine receptor expressed in the MC and NSM pharyngeal neurons. J Neurochem 94:181-191
50. Roeder T (2005) Tyramine and octopamine: ruling behavior and metabolism. Annu Rev Entomol 50:447-477
51. Rogers CM, Franks CJ, Walker RJ, Burke JF, Holden-Dye L (2001) Regulation of the pharynx of Caenorhabditis elegans by 5-HT, octopamine, and FMRFamide-like neuropeptides. J Neurobiol 49:235-244
52. Rovati GE, Capra V, Neubig RR (2007) The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state. Mol Pharmacol 71:959-964
53. Sanyal S, Wintle RF, Kindt KS, Nuttley WM, Arvan R, Fitzmaurice P, Bigras E, Merz DC, Hebert TE, van der Kooy D, Schafer WR, Culotti JG, Van Tol HH (2004) Dopamine modulates the plasticity of mechanosensory responses in Caenorhabditis elegans. EMBO J 23:473-482
54. Schmauss C (1996) Enhanced cleavage of an atypical intron of dopamine D3-receptor pre-mRNA in chronic schizophrenia. J Neurosci 16:7902-7909
55. Schwinn DA (1993) Adrenoceptors as models for G protein-coupled receptors: structure, function and regulation. Br J Anaesth 71:77-85
56. Sealfon SC, Chi L, Ebersole BJ, Rodic V, Zhang D, Ballesteros JA, Weinstein H (1995) Related contribution of specific helix 2 and 7 residues to conformational activation of the serotonin 5-HT2A receptor. J Biol Chem 270:16683-16688
57. Solovyev V, Kosarev P, Seledsov I, Vorobyev D (2006) Automatic annotation of eukaryotic genes, pseudogenes and promoters. Genome Biol 7(Suppl 1):S10.1-12
58. Soyer OS, Dimmic MW, Neubig RR, nd Goldstein RA (2003) Dimerization in aminergic G-protein-coupled receptors: application of a hidden-site class model of evolution. Biochemistry 42:14522-14531
59. Stein LD, Bao Z, Blasiar D, Blumenthal T, Brent MR, Chen N, Chinwalla A, Clarke L, Clee C, Coghlan A, Coulson A, D'Eustachio P, Fitch DH, Fulton LA, Fulton RE, Griffiths-Jones S, Harris TW, Hillier LW, Kamath R, Kuwabara PE, Mardis ER, Marra MA, Miner TL, Minx P, Mullikin JC, Plumb RW, Rogers J, Schein JE, Sohrmann M, Spieth J, Stajich JE, Wei C, Willey D, Wilson RK, Durbin R, Waterston RH (2003) The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol 1:E45
60. Streit A, Li W, Robertson B, Schein J, Kamal IH, Marra M, Wood WB (1999) Homologs of the Caenorhabditis elegans masculinizing gene her-1 in C. briggsae and the filarial parasite Brugia malayi. Genetics 152:1573-1584
61. Suo S, Ishiura S, Van Tol HH (2004) Dopamine receptors in C. elegans. Eur J Pharmacol 500:159-166
62. Suo S, Kimura Y, Van Tol HH (2006) Starvation induces cAMP response element-binding protein-dependent gene expression through octopamine-Gq signaling in Caenorhabditis elegans. J Neurosci 26:10082-10090
63. Tsalik EL, Niacaris T, Wenick AS, Pau K, Avery L, Hobert O (2003) LIM homeobox gene-dependent expression of biogenic amine receptors in restricted regions of the C. elegans nervous system. Dev Biol 263:81-102
64. Vanfleteren JR, Van de Peer Y, Blaxter ML, Tweedie SA, Trotman C, Lu L, Van Hauwaert ML, Moens L (1994) Molecular genealogy of some nematode taxa as based on cytochrome c and globin amino acid sequences. Mol Phylogenet Evol 3:92-101
65. Visiers I, Hassan SA, Weinstein H (2001) Differences in conformational properties of the second intracellular loop (IL2) in 5HT(2C) receptors modified by RNA editing can account for G protein coupling efficiency. Protein Eng 14:409-414
66. Whitton C, Daub J, Quail M, Hall N, Foster J, Ware J, Ganatra M, Slatko B, Barrell B, Blaxter M (2004) A genome sequence survey of the filarial nematode Brugia malayi: repeats, gene discovery, and comparative genomics. Mol Biochem Parasitol 137:215-227
67. Williams SA, Lizotte-Waniewski MR, Foster J, Guiliano D, Daub J, Scott AL, Slatko B, Blaxter ML (2000) The filarial genome project: analysis of the nuclear, mitochondrial and endosymbiont genomes of Brugia malayi. Int J Parasitol 30:411-419
68. Xie J, Dernovici S, Ribeiro P (2005) Mutagenesis analysis of the serotonin 5-HT2C receptor and a Caenorhabditis elegans 5-HT2 homologue: conserved residues of helix 4 and helix 7 contribute to agonist-dependent activation of 5-HT2 receptors. J Neurochem 92:375-387
69. Zuurmond HM, Hessling J, Bluml K, Lohse M, Ijzerman AP (1999) Study of interaction between agonists and asn293 in helix VI of human beta(2)-adrenergic receptor. Mol Pharmacol 56:909-916