Influence of interindividual variability of aldose reductase protein content on polyol-pathway metabolites and redox state in erythrocytes in diabetic patients

Diabetes Care

Volumn 21, Issue 6, 1998, Pages 1014-1018

  Hamada, Yoji ^a   Nishimura, Chihiro ^b   Koh, Naoki ^a   Sakakibara, Fumihiko ^a   Nakamura, Jiro ^a   Tanimoto, Tsyoshi ^c   Hotta, Nigishi ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; FRUCTOSE; GLUCOSE; HEMOGLOBIN A1C; LACTIC ACID; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; POLYOL; PYRUVIC ACID; RECOMBINANT ENZYME; SORBITOL;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC ANGIOPATHY; DIABETIC RETINOPATHY; ENZYME ACTIVITY; ERYTHROCYTE; FEMALE; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; MALE; MICROANGIOPATHY; OXIDATION REDUCTION REACTION; PROTEIN CONTENT;

ALDEHYDE REDUCTASE; ANTIBODIES; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; ENZYME-LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTES; FEMALE; FRUCTOSE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; LACTATES; MALE; MIDDLE AGED; OXIDATION-REDUCTION; PYRUVATES; RECOMBINANT PROTEINS; REFERENCE VALUES; REGRESSION ANALYSIS; SORBITOL;

EID: 3643081248     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.21.6.1014     Document Type: Article

References (31)

1. Kinoshita JH, Merola LO, Satoh K, Dikmac E: Osmotic changes caused by accumulation of dulcitol in the lenses of rats fed with galactose. Nature 194:1085-1087, 1962
2. Greene DA, Lattimer SA, Sima AA: Sorbitol, phosphoinositides, and sodium-potassiumATPase in the pathogenesis of diabetic complications. N Engl J Med 316:599-606, 1987
3. Williamson JR, Cheng K, Frangos M, Hasan KS, Ido Y, Kawamura T, Nyengaard JR, Van den Enden M, Kilo C, Tilton RG: Hyperglycemie pseudohypoxia and diabetic complications. Diabetes 42:801-813, 1993
4. Raskin P, Rosenstock J: Aldose reductase inhibitors and diabetic complications. Am J Med 83:298-306, 1987
5. Hotta N, Sakamoto N: Aldose reductase inhibitors. In The Diabetes Annual Alberti KGMM, Krall LP, Eds. Amsterdam, Elsevier, 1990, p. 330-361
6. Hamada Y, Kitoh R, Raskin P: Crucial role of aldose reductase activity and plasma glucose level in sorbitol accumulation in erythrocytes from diabetic patients. Diabetes 40:1233-1240, 1991
7. Dent MT, Tebbs SE, Gonzalez AM, Ward JD, Wilson RM: Neutrophil aldose reductase activity and its association with established diabetic microvascular complications. Diabet Med 8:439-442, 1991
8. Endo T, Iwata N, Inazu N, Kara S, Kano S, Kuriiwa F, Sato Y, Satoh T: Interindividual variability of hepatic carbonyl reductase levels in Japanese. In Advancement of Forensic Science. Bernhard J, Bonte W, Eds. Berlin, Verlag Chemie, 1995, p. 27-31
9. Nishimura C, Hamada Y, Tachikawa T, Ishikawa T, Gui T, Tsubouchi J, Hotta N, Tanimoto T, Urakami T: Enzyme immunoassay for erythrocyte aldose reductase. Clin Chem 40:889-894, 1994
10. Stevens MJ, Henry DN, Thomas TR Killen PD, Greene DA: Aldose reductase gene expression and osmotic deregulation in cultured human retinal pigment epithelial cells. Am J Physiol 265:E428-E438, 1993
11. Travis SF, Morrison AD, Clements RS, Winegrad AI, Oski FA: Metabolic alterations in the human erythrocyte produced by increases in glucose concentration: the role of the polyol pathway. J Clin Invest 50:2104-2112, 1971
12. Liao JC, Rountree M, Good R, Hook J, Punko C: Determination of D-sorbitol in human erythrocytes by an improved enzymatic method with fluorometric detection. Clin Chem 34:2327-2330, 1988
13. Cooper GR: Methods for determining the amount of glucose in blood, Crit Rev Clin Lab Sci 4:101-145, 1973
14. Bernt E, Bergmeyer HU: D-fructose. In Methods of Enzymatic Analysis. Bergmeyer HU, Ed. Weinheim, Germany, Verlag Chemie, 1974, p. 1304-1307
15. Gutmann I, Wahlefeld AW: L-(+)-Lactate: determination with lactate dehydrogenase and NAD. In Methods of Enzymatic Analysis. Bergmeyer HU, Ed. Weinheim, Germany, Verlag Chemie, 1974, p. 1464-1468
16. Czok R, Lamprecht W: Pyruvate, phosphoenolpyruvate and D-glycerate-2-phosphate. In Methods of Enzymatic Analysis. Bergmeyer HU, Ed. Weinheim, Verlag Chemie, 1974, p. 1447-1451
17. Ratliff DM, Vander Jagt DJ, Eaton RP, Vander Jagt DL: Increased levels of methylglyoxal- metabolizing enzymes in mononuclear and polymorphonuclear cells from insulindependent diabetic patients with diabetic complications: aldose reductase, glyoxalase I, and glyoxalase II: a clinical research center study. J Clin Endocrinol Metab 81:488-492, 1996
18. Williamson DH, Lund P, Krebs HA: The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Biochem J 103:514-527, 1967
19. 2 in human umbilical vein endothelial cells cultured in high glucose medium. Diabetologia 37:262-269, 1994
20. Cameron NE, Cotter MA: Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: role of polyol pathway Diabetologia 35:1011-1019, 1992
21. Suárez G, Rajaram R, Bhuyan KC, Oronsky AL, Goidl JA: Administration of an aldose reductase inhibitor induces a decrease of collagen fluorescence in diabetic rats, J Clin Invest 82:624-627, 1988
22. Szwergold BS, Kappler F, Brown TR: Identification of fructose 3-phosphate in the lens of diabetic rats. Science 247:451-454, 1990
23. Hamada Y, Odagaki Y, Sakakibara F, Naruse K, Koh N, Hotta N: Effects of an aldose reductase inhibitor on erythrocyte fructose 3-phosphate and sorbitol 3-phosphate levels in diabetic patients, Life Sci 57:23-29, 1995
24. Nishimura C, Saito T Ito T, Omori Y, Tanimoto T: High levels of erythrocyte aldose reductase and diabetic retinopathy in NIDDM patients. Diabetologia 37:328-330, 1994
25. Nishimura C, Hotta Y, Gui T, Seko A, Fujimaki T, Ishikawa T, Hayakawa M, Kanai A, Saito T: The level of erythrocyte aldose reductase is associated with the severity of diabetic retinopathy. Diabetes Res Clin Pract 37:173-177, 1997
26. Hamada Y, Kitoh R, Raskin P: Association of erythrocyte aldose reductase activity with diabetic complications in type 1 diabetes mellitus. Diabet Med 10:33-38, 1993
27. Heesom AE, Hibberd ML, Millward A, Demaine AG: Polymorphism in the 5′-end of the aldose reductase gene is strongly associated with the development of diabetic nephropathy in type I diabetes, Dia- betes 46:287-291, 1997
28. n dinucleotide repeat polymorphic marker at the 5′ end of the aldose reductase gene is associated with early-onset diabetic retinopathy in NIDDM patients. Diabetes 44:727-732, 1995
29. Nakamura J, Koh N, Sakakibara F, Hamada Y, Wakao T, Hara T, Mori K, Nakashima E, Naruse K, Hotta N: Polyol pathway, 2,3diphosphoglycerate in erythrocytes and diabetic neuropathy in rats. Eur J Pharmacol 294:207-214, 1996
30. Kawamura T, Suzuki K, Matsumae H, Sano T, Sakamoto N, Hotta N: Effects of glucose and SNK-860, an aldose reductase inhibitor, on the polyol pathway and chemiluminescence response of human neutrophils in vitro. Diabet Med 12:392-396, 1995
31. Hotta N, Koh N, Sakakibara F, Nakamura J, Hamada Y, Hara T, Takeuchi N, Inukai S, Kasama N, Fukasawa H, Kakuta H: An aldose reductase inhibitor, TAT, prevents electroretinographic abnormalities and ADP-induced hyperaggregability in streptozotocin-induced diabetic rats. Eur J Clin Invest 25:948-954, 1995