Increased Levels of Methylglyoxal-Metabolizing Enzymes in Mononuclear and Polymorphonuclear Cells from Insulin-Dependent Diabetic Patients with Diabetic Complications: Aldose Reductase, Glyoxalase I, and Glyoxalase II - A Clinical Research Center Study

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 2, 1996, Pages 488-492

  Ratliff, D M ^a   Vander Jagt, D J ^a   Eaton, R P ^a   Vander Jagt, D L ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; HYDROXYACYLGLUTATHIONE HYDROLASE; LACTOYLGLUTATHIONE LYASE; METHYLGLYOXAL;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; ENZYME BLOOD LEVEL; ENZYME METABOLISM; FEMALE; GLUCOSE METABOLISM; GLYCATION; HUMAN; INFECTIOUS COMPLICATION; INSULIN DEPENDENT DIABETES MELLITUS; MALE; METABOLIC RATE; MONONUCLEAR CELL; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL;

ADULT; AGED; ALDEHYDE REDUCTASE; DIABETES MELLITUS, TYPE 1; FEMALE; GLUTATHIONE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; LACTOYLGLUTATHIONE LYASE; LEUKOCYTES; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; NEUTROPHILS; THIOLESTER HYDROLASES;

EID: 0030041937     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.81.2.8636255     Document Type: Article

References (33)

1. Monníer VM, Kohn RR, Cerami A. 1984 Accelerated age-related browning of human collagen in diabetes mellitus. Proc Natl Acad Sci USA. 81:583-587.
2. Brownlee M, Cerami A, Vlassara H. 1988 Advanced glycosylation endproducts in tissue and the biochemical basis of diabetic complications. N Engl J Med. 318:1315-1321.
3. Bacala R, Cerami A. 1992 Advanced glycosylation: chemistry, biology, and implications for diabetes and aging. Adv Pharmacol 23:1-34.
4. Kato, H, Hayase, F, Shin, DB, Oimomi, M, Baba, S. 1989 3-Deoxyglucosone, an intermediate product of the Maillard reaction. Prog Clin Biol Res. 304:69-84.
5. Knecht, KG, Feather, MS, Baynes, JW. 1992 Detection of 3-deoxyfructose and 3-deoxyglucosone in human urine and plasma: evidence for intermediate stages of the Maillard reaction in vivo. Arch Biochem Biophys. 294:130-137.
6. Cheng R-Z, Uchida K, Kawakishi S. 1992 Selective oxidation of histidine residues in proteins or peptides through the copper(II)-catalysed autoxidation of glucosone. Biochem J. 285:667-671.
7. Nagaraj RH, Dell DR, Prabhakaram M, Ortwerth BJ, Monnier VM. 1991 High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis. Proc Natl Acad Sci USA. 88:10257-10261.
8. Ortwerth BJ, Olesen PR. 1988 Ascorbic acid-induced crosslinking of lens proteins: evidence supporting a Maillard reaction. Biochim Biophys Acta. 956:10-22.
9. Szwergold BS, Kappler F, Brown TR. 1990 Identification of fructose 3-phosphate in the lens of diabetic rats. Science. 247:451-454.
10. Lal S, Szwergold BS, Taylor AH, et al. 1995 Metabolism of fructose-3-phosphate in the diabetic rat lens. Arch Biochem Biophys. 318:191-199.
11. Vander Jagt DL, Robinson B, Taylor KK, Hunsaker LA. 1992 Reduction of trioses by NADPH-dependent aldo-keto reductases: aldose reductase, methylglyoxal and diabetic complications. J Biol Chem. 67:4364-4369.
12. McLellan AC, Thornalley PJ, Benn J, Sonksen PH. 1994 Glyoxalase system in diabetes mellitus and correlation with diabetic complications. Clin Sci. 87:21-29.
13. Ohmori S, Mori M, Shiraha K, Kawase M. 1989 Biosynthesis and degradation of methylglyoxal in animais. Prog Clin Biol Res 290:397-412.
14. Richard JP. 1991 Kinetic parameters for the elimination reaction catalyzed by triosephosphate isomerase and an estimation of the reaction's physiological significance. Biochemistry. 30:4581-4585.
15. Casazza JP, Felver ME, Veech RL. 1984 The metabolism of acetone in rat. J Biol Chem. 259:231-236.
16. Aleksandrovskii YaA. 1992 Antithrombin III, CI inhibitor, methylglyoxal, and polymorphonuclear leukocytes in the development of vascular complications in diabetes mellitus. Thrombosis Res. 67:179-189.
17. Vander Jagt DL. 1989 The glyoxalase system. In: Dolphin D, Poulson R, Avramovic O, eds. Glutathione: chemical, biochemical, and medical aspects, part A. New York: Wiley and Sons; 598-641.
18. Kador PF, Kinoshita JH. 1985: Role of aldose reductase in the development of diabetes- associated complications. Am J Med. 79(Suppl 5A):8-12.
19. Kinoshita JH, Nishimura C. 1988 The involvement of aldose reductase in diabetic complications. Diabetes Metab Rev. 4:323-337.
20. Greene D. 1988 The pathogenesis and prevention of diabetic neuropathy and nephropathy. Metabolism. 37(Suppl 1):25-29.
21. Kador PF. 1988 The role of aldose reductase in the development of diabetic complications. Med Res Rev. 8:325-352.
22. Yamaoka T, Nishimura C, Yamashita K, et al. 1995 Acute onset of diabetic pathological changes in transgenic mice with human aldose reductase cDNA. Diabetologia. 38:255-261.
23. Lee AYW, Chung SK, Chung SSM. 1995 Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens. Proc Natl Acad Sci USA. 92:2780-2784.
24. Griffey RH, Eaton RP, Sibbitt RR, Sibbitt Jr WL, Bicknell JM. 1988 Diabetic neuropathy: structural analysis of nerve hydration by magnetic resonance spectroscopy. JAMA. 260:2872-2878.
25. Vander Jagt DL, Robinson B, Taylor KK, Hunsaker LA. 1990 Aldose reductase from human skeletal and heart muscle. J Biol Chem. 265:20982-20987.
26. Vandet Jagt DL, Hunsaker LA, Robinson B, Stangebye LA, Deck LM. 1990 Aldehyde and aldose reductase from human placenta. J Biol Chem. 265:10912-10918.
27. Flohe L. 1989 The selenoprotein glutathione peroxidase. In. Dolphin D, Poulson R, Avramovic O, eds. Glutathione: chemical, biochemical, and medical aspects, part A. New York: Wiley and Sons; 644-731.
28. Jakoby WB. 1978 The glutathione S-transferases: a group of multifunctional detoxification proteins. Adv Enzymol. 46:383-415.
29. Crabbe MJC, Halder AB, Peckar CO, Cheng H. 1980 Erythrocyte glyceraldehyde-reductase levels in diabetics with retinopathy and cataract. Lancet. 2:1268-1270.
30. Crabbe MJC, Bron AJ, Peckar CO, Petchey M, Ting H-H, Howard-Williams J. 1983 NADPH-oxidising activity in lens and erythrocytes in diabetic and nondiabetic patients with cataract. Br J Ophthalmol. 67:696-699.
31. Hamada Y, Kito R, Raskin P. 1991 Increased erythrocyte aldose reductase activity in type 1 diabetic patients. Diabetic Med. 8:226-231.
32. Hamada Y, Kitoh R, Raskin P. 1993 Association of erythrocyte aldose reductase activity with diabetic complications in type 1 diabetes mellitus. Diabetic Med. 10:33-38.
33. Nishimura C, Saito T, Ito T, Omori Y, Tanimoto T. 1994 High levels of erythrocyte aldose reductase and diabetic retinopathy in NIDDM patients. Diabetologia. 37:328-330.