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Volumn 35, Issue 12, 2007, Pages 2139-2142

Utility of the coefficient of determination (r2) in assessing the accuracy of interspecies allometric predictions: Illumination or illusion?

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ALLOMETRY; ARTICLE; BODY WEIGHT; DRUG CLEARANCE; MATHEMATICAL ANALYSIS; MONKEY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SIMULATION; STATISTICAL ANALYSIS;

EID: 36349035496     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.016444     Document Type: Article
Times cited : (14)

References (9)
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  • 2
    • 0027275566 scopus 로고
    • Physiological parameters in laboratory animals and humans
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  • 3
    • 85046914133 scopus 로고    scopus 로고
    • Allometric scaling of xenobiotic clearance: Uncertainty versus university
    • Hu TM and Hayton WL (2001) Allometric scaling of xenobiotic clearance: uncertainty versus university. AAPS PharmSci 3:1-14.
    • (2001) AAPS PharmSci , vol.3 , pp. 1-14
    • Hu, T.M.1    Hayton, W.L.2
  • 4
    • 23844500635 scopus 로고    scopus 로고
    • Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure
    • Jolivette LJ and Ward KW (2006) Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: molecular properties associated with extrapolative success or failure. J Pharm Sci 94:467-483.
    • (2006) J Pharm Sci , vol.94 , pp. 467-483
    • Jolivette, L.J.1    Ward, K.W.2
  • 5
    • 0029828960 scopus 로고    scopus 로고
    • Interspecies scaling: Predicting clearance of drugs in humans. Three different approaches
    • Mahmood I and Balian JD (1996) Interspecies scaling: predicting clearance of drugs in humans. Three different approaches. Xenobiotica 26:887-895.
    • (1996) Xenobiotica , vol.26 , pp. 887-895
    • Mahmood, I.1    Balian, J.D.2
  • 6
    • 4844222525 scopus 로고    scopus 로고
    • A comprehensive analysis of the role of correction factors in the allometric predictivity of clearance from rat, dog and monkey to humans
    • Nagilla R and Ward KW (2004) A comprehensive analysis of the role of correction factors in the allometric predictivity of clearance from rat, dog and monkey to humans. J Pharm Sci 93:2522-2534.
    • (2004) J Pharm Sci , vol.93 , pp. 2522-2534
    • Nagilla, R.1    Ward, K.W.2
  • 7
    • 17744412689 scopus 로고
    • Allometric scaling in comparative biology: Problems of concept and method
    • Smith RJ (1984) Allometric scaling in comparative biology: problems of concept and method. Am J Physiol 246:R152-R160.
    • (1984) Am J Physiol , vol.246
    • Smith, R.J.1
  • 8
    • 23944475573 scopus 로고    scopus 로고
    • Accuracy of allometrically predicted pharmacokinetic parameters in humans: Role of species selection
    • Tang H and Mayersohn M (2005) Accuracy of allometrically predicted pharmacokinetic parameters in humans: role of species selection. Drug Metab Dispos 33:1288-1293.
    • (2005) Drug Metab Dispos , vol.33 , pp. 1288-1293
    • Tang, H.1    Mayersohn, M.2
  • 9
    • 33344457255 scopus 로고    scopus 로고
    • A global examination of allometric scaling for predicting human drug clearance and the prediction of large vertical allometry
    • Tang H and Mayersohn M (2006) A global examination of allometric scaling for predicting human drug clearance and the prediction of large vertical allometry. J Pharm Sci 95:1783-1799.
    • (2006) J Pharm Sci , vol.95 , pp. 1783-1799
    • Tang, H.1    Mayersohn, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.