메뉴 건너뛰기




Volumn 67, Issue 17, 2007, Pages 2557-2584

Defining the role of insulin detemir in basal insulin therapy

Author keywords

Diabetes mellitus, treatment; Insulin detemir, general

Indexed keywords

ACETYLSALICYLIC ACID; BIPHASIC INSULIN; DIAZEPAM; FATTY ACID; GLIBENCLAMIDE; GLUCOSE; HUMAN INSULIN; IBUPROFEN; INSULIN; INSULIN ASPART; INSULIN DETEMIR; INSULIN GLARGINE; INSULIN RECEPTOR; ISOPHANE INSULIN; ORAL ANTIDIABETIC AGENT; PHENYLBUTAZONE; TOLBUTAMIDE; VALPROIC ACID; WARFARIN;

EID: 36348988955     PISSN: 00126667     EISSN: 00126667     Source Type: Journal    
DOI: 10.2165/00003495-200767170-00007     Document Type: Review
Times cited : (35)

References (99)
  • 1
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • United Kingdom Prospective Diabetes Study (UKPDS) Group
    • United Kingdom Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352: 837-53
    • (1998) Lancet , vol.352 , pp. 837-853
  • 2
    • 0029147687 scopus 로고
    • Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: A randomized prospective 6-year study
    • Ohkubo Y, Kishikawa H, Araki E, et al. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study. Diabetes Res Clin Pract 1995; 28: 103-17
    • (1995) Diabetes Res Clin Pract , vol.28 , pp. 103-117
    • Ohkubo, Y.1    Kishikawa, H.2    Araki, E.3
  • 3
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • Diabetes Control and Complications Trial Research Group
    • Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329: 977-86
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 4
    • 0036733076 scopus 로고    scopus 로고
    • Before oral agents fail: The case for starting insulin early
    • Marre M. Before oral agents fail: the case for starting insulin early. Int J Obes Relat Metab Disord 2002; 26 Suppl. 3: S25-30
    • (2002) Int J Obes Relat Metab Disord , vol.26 , Issue.SUPPL. 3
    • Marre, M.1
  • 5
    • 25444441553 scopus 로고    scopus 로고
    • Kurtzhals P. How to achieve a predictable basal insulin? Diabetes Metab 2005; 31: 4S25-33
    • Kurtzhals P. How to achieve a predictable basal insulin? Diabetes Metab 2005; 31: 4S25-33
  • 7
    • 0023829632 scopus 로고
    • Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects
    • Polonsky KS, Given BD, van Cauter E. Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. J Clin Invest 1988; 81: 442-8
    • (1988) J Clin Invest , vol.81 , pp. 442-448
    • Polonsky, K.S.1    Given, B.D.2    van Cauter, E.3
  • 8
    • 0032896693 scopus 로고    scopus 로고
    • Improved postprandial glycemic control with insulin aspart: A randomized double-diabetes, blind cross-over trial in type 1 diabetes
    • Lindholm A, McEwen J, Riis AP. Improved postprandial glycemic control with insulin aspart: a randomized double-diabetes, blind cross-over trial in type 1 diabetes. Diabetes Care 1999; 22: 801-5
    • (1999) Diabetes Care , vol.22 , pp. 801-805
    • Lindholm, A.1    McEwen, J.2    Riis, A.P.3
  • 9
    • 0036034873 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of insulin lispro mixtures
    • Roach P, Woodworth JR. Clinical pharmacokinetics and pharmacodynamics of insulin lispro mixtures. Clin Pharmacokinet 2002; 41: 1043-57
    • (2002) Clin Pharmacokinet , vol.41 , pp. 1043-1057
    • Roach, P.1    Woodworth, J.R.2
  • 10
    • 0037737732 scopus 로고    scopus 로고
    • Outpatient insulin therapy in type 1 and type 2 diabetes mellitus: Scientific review
    • DeWitt DE, Hirsch IB. Outpatient insulin therapy in type 1 and type 2 diabetes mellitus: scientific review. JAMA 2003; 289: 2254-64
    • (2003) JAMA , vol.289 , pp. 2254-2264
    • DeWitt, D.E.1    Hirsch, I.B.2
  • 11
    • 0034117810 scopus 로고    scopus 로고
    • Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo
    • Heinemann L, Linkeschova R, Rave K, et al. Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo. Diabetes Care 2000; 23: 644-9
    • (2000) Diabetes Care , vol.23 , pp. 644-649
    • Heinemann, L.1    Linkeschova, R.2    Rave, K.3
  • 12
    • 20944432717 scopus 로고    scopus 로고
    • A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir
    • Plank J, Bodenlenz M, Sinner F, et al. A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir. Diabetes Care 2005; 28: 1107-12
    • (2005) Diabetes Care , vol.28 , pp. 1107-1112
    • Plank, J.1    Bodenlenz, M.2    Sinner, F.3
  • 13
    • 0036410334 scopus 로고    scopus 로고
    • Variability of insulin absorption and insulin action
    • Heinemann L. Variability of insulin absorption and insulin action. Diabetes Technol Ther 2002; 4: 673-82
    • (2002) Diabetes Technol Ther , vol.4 , pp. 673-682
    • Heinemann, L.1
  • 14
    • 36348971630 scopus 로고    scopus 로고
    • Insulins
    • American Society of Health-System Pharmacists, McEvoy GK, Snow EK, Kester L, et al, editors, Bethesda MD, ASHP
    • American Society of Health-System Pharmacists. Insulins. In: McEvoy GK, Snow EK, Kester L, et al., editors. AHFS drug information 2007. Bethesda (MD): ASHP, 2007: 3140-51
    • (2007) AHFS drug information 2007 , pp. 3140-3151
  • 15
    • 11844250564 scopus 로고    scopus 로고
    • Insulin analogues
    • Hirsch IB. Insulin analogues. N Engl J Med 2005; 352: 174-83
    • (2005) N Engl J Med , vol.352 , pp. 174-183
    • Hirsch, I.B.1
  • 16
    • 0023936777 scopus 로고
    • Monomeric insulins obtained by protein engineering and their medical implications
    • Brange J, Ribel U, Hansen JF, et al. Monomeric insulins obtained by protein engineering and their medical implications. Nature 1988; 333: 679-82
    • (1988) Nature , vol.333 , pp. 679-682
    • Brange, J.1    Ribel, U.2    Hansen, J.F.3
  • 18
    • 0034609223 scopus 로고    scopus 로고
    • Insulin glargine
    • Bolli GB, Owens DR. Insulin glargine. Lancet 2000; 356: 443-5
    • (2000) Lancet , vol.356 , pp. 443-445
    • Bolli, G.B.1    Owens, D.R.2
  • 19
    • 4444307704 scopus 로고    scopus 로고
    • Improved glycemic control without an increase in severe hypoglycemic episodes in intensively treated patients with type 1 diabetes receiving morning, evening, or split dose insulin glargine
    • Garg SK, Gottlieb PA, Hisatomi ME, et al. Improved glycemic control without an increase in severe hypoglycemic episodes in intensively treated patients with type 1 diabetes receiving morning, evening, or split dose insulin glargine. Diabetes Res Clin Pract 2004; 66: 49-56
    • (2004) Diabetes Res Clin Pract , vol.66 , pp. 49-56
    • Garg, S.K.1    Gottlieb, P.A.2    Hisatomi, M.E.3
  • 20
    • 0033867021 scopus 로고    scopus 로고
    • Less nocturnal hypoglycemia and better post-dinner glucose control with bedtime insulin glargine compared with bedtime NPH insulin during insulin combination therapy in type 2 diabetes
    • Yki-Jarvinen H, Dressler A, Ziemen M. Less nocturnal hypoglycemia and better post-dinner glucose control with bedtime insulin glargine compared with bedtime NPH insulin during insulin combination therapy in type 2 diabetes. Diabetes Care 2000; 23: 1130-6
    • (2000) Diabetes Care , vol.23 , pp. 1130-1136
    • Yki-Jarvinen, H.1    Dressler, A.2    Ziemen, M.3
  • 21
    • 0034827469 scopus 로고    scopus 로고
    • Basal insulin therapy in type 2 diabetes: 28-week comparison of insulin glargine (HOE 901) and NPH insulin
    • Rosenstock J, Schwartz SL, Clark Jr CM, et al. Basal insulin therapy in type 2 diabetes: 28-week comparison of insulin glargine (HOE 901) and NPH insulin. Diabetes Care 2001; 24: 631-6
    • (2001) Diabetes Care , vol.24 , pp. 631-636
    • Rosenstock, J.1    Schwartz, S.L.2    Clark Jr, C.M.3
  • 22
    • 0343851573 scopus 로고    scopus 로고
    • Efficacy and safety of HOE 901 versus NPH insulin in patients with type 1 diabetes: The European Study Group of HOE 901 in type 1 diabetes
    • Pieber TR, Eugene-Jolchine I, Derobert E. Efficacy and safety of HOE 901 versus NPH insulin in patients with type 1 diabetes: The European Study Group of HOE 901 in type 1 diabetes. Diabetes Care 2000; 23: 157-62
    • (2000) Diabetes Care , vol.23 , pp. 157-162
    • Pieber, T.R.1    Eugene-Jolchine, I.2    Derobert, E.3
  • 23
    • 0033766190 scopus 로고    scopus 로고
    • A 16-week comparison of the novel insulin analog insulin glargine (HOE 901) and NPH human insulin used with insulin lispro in patients with type 1 diabetes
    • Raskin P, Klaff L, Bergenstal R, et al. A 16-week comparison of the novel insulin analog insulin glargine (HOE 901) and NPH human insulin used with insulin lispro in patients with type 1 diabetes. Diabetes Care 2000; 23: 1666-71
    • (2000) Diabetes Care , vol.23 , pp. 1666-1671
    • Raskin, P.1    Klaff, L.2    Bergenstal, R.3
  • 24
    • 2942574527 scopus 로고    scopus 로고
    • Effects of QD insulin detemir or neutral protamine Hagedorn on blood glucose control in patients with type I diabetes mellitus using basal-bolus regimen
    • Russell-Jones D, Simpson R, Hylleberg B, et al. Effects of QD insulin detemir or neutral protamine Hagedorn on blood glucose control in patients with type I diabetes mellitus using basal-bolus regimen. Clin Ther 2004; 26: 724-36
    • (2004) Clin Ther , vol.26 , pp. 724-736
    • Russell-Jones, D.1    Simpson, R.2    Hylleberg, B.3
  • 25
    • 33748555885 scopus 로고    scopus 로고
    • Insulin detemir lowers the risk of hypoglycaemia and provides more consistent plasma glucose levels compared with NPH insulin in type 1 diabetes
    • Kolendorf K, Ross GP, Pavlic-Renart I, et al. Insulin detemir lowers the risk of hypoglycaemia and provides more consistent plasma glucose levels compared with NPH insulin in type 1 diabetes. Diabet Med 2006; 23: 729-35
    • (2006) Diabet Med , vol.23 , pp. 729-735
    • Kolendorf, K.1    Ross, G.P.2    Pavlic-Renart, I.3
  • 26
    • 21744451635 scopus 로고    scopus 로고
    • Comparison of three multiple injection regimens for type 1 diabetes: Morning plus dinner or bedtime administration of insulin detemir vs. morning plus bedtime NPH insulin
    • Pieber TR, Draeger E, Kristensen A, et al. Comparison of three multiple injection regimens for type 1 diabetes: morning plus dinner or bedtime administration of insulin detemir vs. morning plus bedtime NPH insulin. Diabet Med 2005; 22: 850-7
    • (2005) Diabet Med , vol.22 , pp. 850-857
    • Pieber, T.R.1    Draeger, E.2    Kristensen, A.3
  • 27
    • 12744274870 scopus 로고    scopus 로고
    • Lower within-subject variability of fasting blood glucose and reduced weight gain with insulin detemir compared to NPH insulin in patients with type 2 diabetes
    • Haak T, Tiengo A, Draeger E, et al. Lower within-subject variability of fasting blood glucose and reduced weight gain with insulin detemir compared to NPH insulin in patients with type 2 diabetes. Diabetes Obes Metab 2005; 7: 56-64
    • (2005) Diabetes Obes Metab , vol.7 , pp. 56-64
    • Haak, T.1    Tiengo, A.2    Draeger, E.3
  • 28
    • 6944244979 scopus 로고    scopus 로고
    • Raslova K, Bogoev M, Raz I, et al. Insulin detemir and insulin aspart: a promising basal-bolus regimen for type 2 diabetes. [published erratum appears in Diabetes Res Clin Pract 2006; 72: 112]. Diabetes Res Clin Pract 2004; 66: 193-201
    • Raslova K, Bogoev M, Raz I, et al. Insulin detemir and insulin aspart: a promising basal-bolus regimen for type 2 diabetes. [published erratum appears in Diabetes Res Clin Pract 2006; 72: 112]. Diabetes Res Clin Pract 2004; 66: 193-201
  • 29
    • 33746391488 scopus 로고    scopus 로고
    • A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naive people with type 2 diabetes
    • Hermansen K, Davies M, Derezinski T, et al. A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naive people with type 2 diabetes. Diabetes Care 2006; 29: 1269-74
    • (2006) Diabetes Care , vol.29 , pp. 1269-1274
    • Hermansen, K.1    Davies, M.2    Derezinski, T.3
  • 30
    • 9944261933 scopus 로고    scopus 로고
    • Insulin detemir: A review of its use in the management of type 1 and 2 diabetes mellitus
    • Chapman TM, Perry CM. Insulin detemir: a review of its use in the management of type 1 and 2 diabetes mellitus. Drugs 2004; 64: 2577-95
    • (2004) Drugs , vol.64 , pp. 2577-2595
    • Chapman, T.M.1    Perry, C.M.2
  • 31
    • 33144488817 scopus 로고    scopus 로고
    • Insulin detemir: From concept to clinical experience
    • Home P, Kurtzhals P. Insulin detemir: from concept to clinical experience. Expert Opin Pharmacother 2006; 7: 325-43
    • (2006) Expert Opin Pharmacother , vol.7 , pp. 325-343
    • Home, P.1    Kurtzhals, P.2
  • 32
    • 0029619489 scopus 로고
    • Albumin binding of insulins acylated with fatty acids: Characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect in vivo
    • Kurtzhals P, Havelund S, Jonassen I, et al. Albumin binding of insulins acylated with fatty acids: characterization of the ligand-protein interaction and correlation between binding affinity and timing of the insulin effect in vivo. Biochem J 1995; 312 (3): 725-31
    • (1995) Biochem J , vol.312 , Issue.3 , pp. 725-731
    • Kurtzhals, P.1    Havelund, S.2    Jonassen, I.3
  • 33
    • 9044226136 scopus 로고    scopus 로고
    • Soluble, fatty acid acylated insulins bind to albumin and show protracted action in pigs
    • Markussen J, Havelund S, Kurtzhals P, et al. Soluble, fatty acid acylated insulins bind to albumin and show protracted action in pigs. Diabetologia 1996; 39: 281-8
    • (1996) Diabetologia , vol.39 , pp. 281-288
    • Markussen, J.1    Havelund, S.2    Kurtzhals, P.3
  • 34
    • 6344281418 scopus 로고    scopus 로고
    • Albumin binding of insulin detemir reduces the risk for hypoglycemic events [abstract]
    • Kurtzhals P, Colding-Jorgensen M. Albumin binding of insulin detemir reduces the risk for hypoglycemic events [abstract]. Diabetes 2004; 53 Suppl. 2: A477
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 2
    • Kurtzhals, P.1    Colding-Jorgensen, M.2
  • 35
    • 6344267133 scopus 로고    scopus 로고
    • Engineering predictability and protraction in Diabasal insulin analogue: The pharmacology of insulin detemir
    • Kurtzhals P. Engineering predictability and protraction in Diabasal insulin analogue: the pharmacology of insulin detemir. Int J Obes 2004; 28 Suppl. 2: S23-8
    • (2004) Int J Obes , vol.28 , Issue.SUPPL. 2
    • Kurtzhals, P.1
  • 36
    • 0036597493 scopus 로고    scopus 로고
    • New insulins in the treatment of diabetes mellitus
    • Lindholm A. New insulins in the treatment of diabetes mellitus. Best Pract Res Clin Gastroenterol 2002; 16: 475-92
    • (2002) Best Pract Res Clin Gastroenterol , vol.16 , pp. 475-492
    • Lindholm, A.1
  • 37
    • 4344701890 scopus 로고    scopus 로고
    • The mechanism of protraction of insulin detemir, a long-acting, acylated analog human insulin
    • Havelund S, Plum A, Ribel U, et al. The mechanism of protraction of insulin detemir, a long-acting, acylated analog human insulin. Pharm Res 2004; 21: 1498-504
    • (2004) Pharm Res , vol.21 , pp. 1498-1504
    • Havelund, S.1    Plum, A.2    Ribel, U.3
  • 38
    • 6344253672 scopus 로고    scopus 로고
    • Effects of insulin detemir on glucose uptake and utilisation in human and rat adipocytes [abstract]
    • Soerensen AR, Tornqvist H. Effects of insulin detemir on glucose uptake and utilisation in human and rat adipocytes [abstract]. Diabetes 2004; 53 Suppl. 2: A558
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 2
    • Soerensen, A.R.1    Tornqvist, H.2
  • 39
    • 9944229843 scopus 로고    scopus 로고
    • Similar binding profiles of insulin detemir and human insulin for insulin receptor isoforms [abstract]
    • Stidsen CE, Albrechtsen KH, Frost M, et al. Similar binding profiles of insulin detemir and human insulin for insulin receptor isoforms [abstract]. Diabetes 2004; 53 Suppl. 2: A331
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 2
    • Stidsen, C.E.1    Albrechtsen, K.H.2    Frost, M.3
  • 40
    • 0342657181 scopus 로고    scopus 로고
    • Correlations receptor binding and metabolic and mitogenic potencies insulin analogs designed for clinical use
    • Kurtzhals P, Schaffer L, Sorensen A, et al. Correlations receptor binding and metabolic and mitogenic potencies insulin analogs designed for clinical use. Diabetes 2000; 49 999-1005
    • (2000) Diabetes , vol.49 , pp. 999-1005
    • Kurtzhals, P.1    Schaffer, L.2    Sorensen, A.3
  • 41
    • 33646530498 scopus 로고    scopus 로고
    • Tissue selectivity of insulin detemir action in vivo
    • Hennige AM, Sartorius T, Tschritter O, et al. Tissue selectivity of insulin detemir action in vivo. Diabetologia 2006; 49: 1274-82
    • (2006) Diabetologia , vol.49 , pp. 1274-1282
    • Hennige, A.M.1    Sartorius, T.2    Tschritter, O.3
  • 42
    • 16844368165 scopus 로고    scopus 로고
    • Comparison of effects on glucose and lipid metabolism of equipotent doses of insulin detemir and NPH insulin with a 16-h euglycaemic clamp
    • Hordern SV, Wright JE, Umpleby AM, et al. Comparison of effects on glucose and lipid metabolism of equipotent doses of insulin detemir and NPH insulin with a 16-h euglycaemic clamp. Diabetologia 2005; 48: 420-6
    • (2005) Diabetologia , vol.48 , pp. 420-426
    • Hordern, S.V.1    Wright, J.E.2    Umpleby, A.M.3
  • 43
    • 0034011079 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic properties of long-acting insulin analogue NN304 in comparison to NPH insulin in humans
    • Brunner GA, Sendhofer G, Wutte A, et al. Pharmacokinetic and pharmacodynamic properties of long-acting insulin analogue NN304 in comparison to NPH insulin in humans. Exp Clin Endocrinol Diabetes 2000; 108: 100-5
    • (2000) Exp Clin Endocrinol Diabetes , vol.108 , pp. 100-105
    • Brunner, G.A.1    Sendhofer, G.2    Wutte, A.3
  • 44
    • 0003852563 scopus 로고    scopus 로고
    • Time-action profile of the soluble, fatty acid acylated, long-acting insulin analogue NN304
    • Heinemann L, Sinha K, Weyer C, et al. Time-action profile of the soluble, fatty acid acylated, long-acting insulin analogue NN304. Diabet Med 1999; 16: 332-8
    • (1999) Diabet Med , vol.16 , pp. 332-338
    • Heinemann, L.1    Sinha, K.2    Weyer, C.3
  • 45
    • 0038114440 scopus 로고    scopus 로고
    • Duration of action, pharmacodynamic profile and between-subject variability of insulin detemir in subjects with type 1 diabetes [abstract]
    • Pieber TR, Plank J, Gorzer E. Duration of action, pharmacodynamic profile and between-subject variability of insulin detemir in subjects with type 1 diabetes [abstract]. Diabetologia 2002; 45 Suppl. 2: A257
    • (2002) Diabetologia , vol.45 , Issue.SUPPL. 2
    • Pieber, T.R.1    Plank, J.2    Gorzer, E.3
  • 46
    • 2542576404 scopus 로고    scopus 로고
    • Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetes
    • Heise T, Nosek L, Ronn BB, et al. Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetes. Diabetes 2004; 53: 1614-20
    • (2004) Diabetes , vol.53 , pp. 1614-1620
    • Heise, T.1    Nosek, L.2    Ronn, B.B.3
  • 47
    • 9944246945 scopus 로고    scopus 로고
    • Comparison of pharmacodynamic and pharmacokinetic dose-response profiles between insulin detemir and NPH insulin in subjects with type 2 diabetes [abstract]
    • Pieber TR, Wutte A, Plank J, et al. Comparison of pharmacodynamic and pharmacokinetic dose-response profiles between insulin detemir and NPH insulin in subjects with type 2 diabetes [abstract]. Diabetes 2004; 53 Suppl. 2: A142
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 2
    • Pieber, T.R.1    Wutte, A.2    Plank, J.3
  • 48
    • 0000513854 scopus 로고    scopus 로고
    • Reduced pharmacokinetic variability (PK) of a novel, long-acting insulin analog [abstract]
    • Strange P, McGill J, Mazzeo M. Reduced pharmacokinetic variability (PK) of a novel, long-acting insulin analog [abstract]. Diabetes 1999; 48 Suppl. 1: A103
    • (1999) Diabetes , vol.48 , Issue.SUPPL. 1
    • Strange, P.1    McGill, J.2    Mazzeo, M.3
  • 49
    • 33947644300 scopus 로고    scopus 로고
    • Albumin-bound basal insulin analogues (insulin detemir and NN344): Comparable time-action profiles but less variability than insulin glargine in type 2 diabetes
    • Klein O, Lynge J, Endahl L, et al. Albumin-bound basal insulin analogues (insulin detemir and NN344): comparable time-action profiles but less variability than insulin glargine in type 2 diabetes. Diabetes Obes Metab 2006; 9 (3): 1-10
    • (2006) Diabetes Obes Metab , vol.9 , Issue.3 , pp. 1-10
    • Klein, O.1    Lynge, J.2    Endahl, L.3
  • 50
    • 33645967817 scopus 로고    scopus 로고
    • Insulin detemir under steady-state conditions: No accumulation and constant metabolic effect over time with twice daily administration in subjects with type 1 diabetes
    • Bott S, Tusek C, Jacobsen LV, et al. Insulin detemir under steady-state conditions: no accumulation and constant metabolic effect over time with twice daily administration in subjects with type 1 diabetes. Diabet Med 2006; 23: 522-8
    • (2006) Diabet Med , vol.23 , pp. 522-528
    • Bott, S.1    Tusek, C.2    Jacobsen, L.V.3
  • 51
    • 0242300708 scopus 로고    scopus 로고
    • Insulin detemir is characterized by a consistent pharmacokinetic profile across age-groups in children, adolescents, and adults with type 1 diabetes
    • Danne T, Lupke K, Walte K, et al. Insulin detemir is characterized by a consistent pharmacokinetic profile across age-groups in children, adolescents, and adults with type 1 diabetes. Diabetes Care 2003; 26: 3087-92
    • (2003) Diabetes Care , vol.26 , pp. 3087-3092
    • Danne, T.1    Lupke, K.2    Walte, K.3
  • 52
    • 0242277757 scopus 로고    scopus 로고
    • Pharmacokinetics of insulin detemir in subjects with renal or hepatic impairment [abstract]
    • Jacobsen LV, Popescu G, Plum A. Pharmacokinetics of insulin detemir in subjects with renal or hepatic impairment [abstract]. Diabetes 2002; 51 Suppl. 2: A102
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 2
    • Jacobsen, L.V.1    Popescu, G.2    Plum, A.3
  • 53
    • 1242343732 scopus 로고    scopus 로고
    • Similarity of insulin detemir pharmacokinetics, safety, and tolerability profiles in healthy Caucasian and Japanese American subjects
    • Jhee SS, Lyness WH, Rojas PB, et al. Similarity of insulin detemir pharmacokinetics, safety, and tolerability profiles in healthy Caucasian and Japanese American subjects. J Clin Pharmacol 2004; 44: 258-64
    • (2004) J Clin Pharmacol , vol.44 , pp. 258-264
    • Jhee, S.S.1    Lyness, W.H.2    Rojas, P.B.3
  • 54
    • 0242341041 scopus 로고    scopus 로고
    • Insulin detemir and NPH insulin: Comparison of pharmacokinetic and pharmacodynamic properties in Japanese and Causasian volunteers [abstract]
    • Rave K, Nosek L, Heinemann L. Insulin detemir and NPH insulin: comparison of pharmacokinetic and pharmacodynamic properties in Japanese and Causasian volunteers [abstract]. Diabetes 2003; 52 Suppl. 1: A453
    • (2003) Diabetes , vol.52 , Issue.SUPPL. 1
    • Rave, K.1    Nosek, L.2    Heinemann, L.3
  • 55
    • 33746910579 scopus 로고    scopus 로고
    • Time-action profile of insulin detemir and NPH insulin in patients with type 2 diabetes from different ethnic groups
    • Hompesch M, Troupin B, Heise T, et al. Time-action profile of insulin detemir and NPH insulin in patients with type 2 diabetes from different ethnic groups. Diabetes Obes Metab 2006; 8: 568-73
    • (2006) Diabetes Obes Metab , vol.8 , pp. 568-573
    • Hompesch, M.1    Troupin, B.2    Heise, T.3
  • 57
    • 0031446132 scopus 로고    scopus 로고
    • Effect of fatty acids and selected drugs on the albumin binding of a long-acting, acylated insulin analogue
    • Kurtzhals P, Havelund S, Jonassen I, et al. Effect of fatty acids and selected drugs on the albumin binding of a long-acting, acylated insulin analogue. J Pharm Sci 1997; 86: 1365-8
    • (1997) J Pharm Sci , vol.86 , pp. 1365-1368
    • Kurtzhals, P.1    Havelund, S.2    Jonassen, I.3
  • 58
    • 2342621441 scopus 로고    scopus 로고
    • Insulin detemir offers improved glycemic control compared with NPH insulin in people with type 1 diabetes: A randomized clinical trial
    • Home P, Bartley P, Russell-Jones D, et al. Insulin detemir offers improved glycemic control compared with NPH insulin in people with type 1 diabetes: a randomized clinical trial. Diabetes Care 2004; 27: 1081-7
    • (2004) Diabetes Care , vol.27 , pp. 1081-1087
    • Home, P.1    Bartley, P.2    Russell-Jones, D.3
  • 59
    • 2442678007 scopus 로고    scopus 로고
    • Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin) in basal-bolus therapy for patients with type 1 diabetes
    • Hermansen K, Fontaine P, Kukolja KK, et al. Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin) in basal-bolus therapy for patients with type 1 diabetes. Diabetologia 2004; 47: 622-9
    • (2004) Diabetologia , vol.47 , pp. 622-629
    • Hermansen, K.1    Fontaine, P.2    Kukolja, K.K.3
  • 60
    • 0038418746 scopus 로고    scopus 로고
    • Insulin detemir is associated with more predictable glycemic control and reduced risk of hypoglycemia than NPH insulin in patients with type 1 diabetes on a basal-bolus regimen with premeal insulin aspart
    • Vague P, Selam JL, Skeie S, et al. Insulin detemir is associated with more predictable glycemic control and reduced risk of hypoglycemia than NPH insulin in patients with type 1 diabetes on a basal-bolus regimen with premeal insulin aspart. Diabetes Care 2003; 26: 590-6
    • (2003) Diabetes Care , vol.26 , pp. 590-596
    • Vague, P.1    Selam, J.L.2    Skeie, S.3
  • 61
    • 0000546699 scopus 로고    scopus 로고
    • Efficacy and safety of 6-month treatment with insulin detemir in type 1 diabetic patients on a basal/bolus regimen [abstract]
    • Roberts A, Standl E, Bayer T, et al. Efficacy and safety of 6-month treatment with insulin detemir in type 1 diabetic patients on a basal/bolus regimen [abstract]. Diabetologia 2001; 44: A207
    • (2001) Diabetologia , vol.44
    • Roberts, A.1    Standl, E.2    Bayer, T.3
  • 62
    • 33846255010 scopus 로고    scopus 로고
    • Insulin detemir compared with NPH insulin in children and adolescents with type 1 diabetes
    • Robertson KJ, Schoenle E, Gucev Z, et al. Insulin detemir compared with NPH insulin in children and adolescents with type 1 diabetes. Diabet Med 2007; 24: 27-34
    • (2007) Diabet Med , vol.24 , pp. 27-34
    • Robertson, K.J.1    Schoenle, E.2    Gucev, Z.3
  • 63
    • 12744274867 scopus 로고    scopus 로고
    • Insulin detemir used in basal-bolus therapy in people with type 1 diabetes is associated with a lower risk of nocturnal hypoglycaemia and less weight gain over 12 months in comparison to NPH insulin
    • de Leeuw I, Vague P, Selam J-L, et al. Insulin detemir used in basal-bolus therapy in people with type 1 diabetes is associated with a lower risk of nocturnal hypoglycaemia and less weight gain over 12 months in comparison to NPH insulin. Diabetes Obes Metab 2005; 7: 73-82
    • (2005) Diabetes Obes Metab , vol.7 , pp. 73-82
    • de Leeuw, I.1    Vague, P.2    Selam, J.-L.3
  • 64
    • 6044261447 scopus 로고    scopus 로고
    • The 12-month efficacy and safety of insulin detemir and NPH insulin in basal-bolus therapy for the treatment of type 1 diabetes
    • Standl E, Lang H, Roberts A. The 12-month efficacy and safety of insulin detemir and NPH insulin in basal-bolus therapy for the treatment of type 1 diabetes. Diabetes Technol Ther 2004; 6: 579-88
    • (2004) Diabetes Technol Ther , vol.6 , pp. 579-588
    • Standl, E.1    Lang, H.2    Roberts, A.3
  • 65
    • 85036992769 scopus 로고    scopus 로고
    • Less glucose variability with insulin detemir compared to NPH insulin in subjects with type 1 diabetes undergoing continuous glucose monitoring [abstract]
    • Jones DR, Clauson P, Ong S, et al. Less glucose variability with insulin detemir compared to NPH insulin in subjects with type 1 diabetes undergoing continuous glucose monitoring [abstract]. Diabetes 2006; 55 Suppl. 1: A118
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Jones, D.R.1    Clauson, P.2    Ong, S.3
  • 66
    • 34249297061 scopus 로고    scopus 로고
    • Comparison of insulin detemir and insulin glargine in subjects with type 1 diabetes using intensive insulin therapy
    • Pieber TR, Treichel HC, Hompesch B, et al. Comparison of insulin detemir and insulin glargine in subjects with type 1 diabetes using intensive insulin therapy. Diabet Med 2007; 24: 635-42
    • (2007) Diabet Med , vol.24 , pp. 635-642
    • Pieber, T.R.1    Treichel, H.C.2    Hompesch, B.3
  • 67
    • 33845980344 scopus 로고    scopus 로고
    • Insulin detemir added to oral anti-diabetic drugs in type 2 diabetes provides glycemic control comparable to insulin glargine with less weight gain [abstract]
    • Rosenstock J, Davies M, Home PD, et al. Insulin detemir added to oral anti-diabetic drugs in type 2 diabetes provides glycemic control comparable to insulin glargine with less weight gain [abstract]. Diabetes 2006; 55 Suppl. 1: A132
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Rosenstock, J.1    Davies, M.2    Home, P.D.3
  • 68
    • 33947422195 scopus 로고    scopus 로고
    • Biphasic insulin aspart 30 (BIAsp30), insulin detemir (IDet) and insulin aspart (IAsp) allow patients with type 2 diabetes to reach A1C target: The PREFER study [abstract]
    • Liebl A, Prager R, Kaiser M, et al. Biphasic insulin aspart 30 (BIAsp30), insulin detemir (IDet) and insulin aspart (IAsp) allow patients with type 2 diabetes to reach A1C target: the PREFER study [abstract]. Diabetes 2006; 55 Suppl. 1: A123
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Liebl, A.1    Prager, R.2    Kaiser, M.3
  • 69
    • 33845236398 scopus 로고    scopus 로고
    • Comparison of once-daily insulin detemir with NPH insulin added to a regimen of oral antidiabetic drugs in poorly controlled type 2 diabetes
    • Philis-Tsimikas A, Charpentier G, Clauson P, et al. Comparison of once-daily insulin detemir with NPH insulin added to a regimen of oral antidiabetic drugs in poorly controlled type 2 diabetes. Clin Ther 2006; 28: 1569-81
    • (2006) Clin Ther , vol.28 , pp. 1569-1581
    • Philis-Tsimikas, A.1    Charpentier, G.2    Clauson, P.3
  • 70
    • 36348961826 scopus 로고    scopus 로고
    • PREDICTIVE™: A global, prospective, observational study to evaluate insulin detemir treatment in type 1 and type 2 diabetes. German Cohort Data [abstract]
    • Luddeke H-J, Hansen JB, Nauck M. PREDICTIVE™: a global, prospective, observational study to evaluate insulin detemir treatment in type 1 and type 2 diabetes. German Cohort Data [abstract]. Diabetes 2006; 55 Suppl. 1: A122
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Luddeke, H.-J.1    Hansen, J.B.2    Nauck, M.3
  • 71
    • 33947704161 scopus 로고    scopus 로고
    • PREDICTIVE: A global, prospective observational study to evaluate insulin detemir treatment in types 1 and 2 diabetes. Baseline characteristics and predictors of hypoglycaemia from the European cohort
    • Luddeke HJ, Sreenan S, Aczel S, et al. PREDICTIVE: a global, prospective observational study to evaluate insulin detemir treatment in types 1 and 2 diabetes. Baseline characteristics and predictors of hypoglycaemia from the European cohort. Diabetes Obes Metab 2007; 9: 428-34
    • (2007) Diabetes Obes Metab , vol.9 , pp. 428-434
    • Luddeke, H.J.1    Sreenan, S.2    Aczel, S.3
  • 72
    • 36349004072 scopus 로고    scopus 로고
    • Switching from a human insulin basal-bolus regimen to insulin analog basal-bolus thertes apy with insulin detemir/insulin aspart improves glycemic control and reduces hypoglycemic episodes in patients with type 1 diabetes: Results from German subgroup of the PREDICTIVE™ study [abstract]
    • Maxeiner S, Hansen JB, Nauck M. Switching from a human insulin basal-bolus regimen to insulin analog basal-bolus thertes apy with insulin detemir/insulin aspart improves glycemic control and reduces hypoglycemic episodes in patients with type 1 diabetes: results from German subgroup of the PREDICTIVE™ study [abstract]. Diabetes 2006; 55 Suppl. 1: A127
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Maxeiner, S.1    Hansen, J.B.2    Nauck, M.3
  • 73
    • 11044238046 scopus 로고    scopus 로고
    • Treatment with insulin detemir in combination with oral agents is associated with less risk of hypoglycaemia and less weight gain than NPH insulin at comparable levels of glycaemic improvement in people with type 2 diabetes [abstract]
    • Hermansen K, Derezinski T, Kim H, et al. Treatment with insulin detemir in combination with oral agents is associated with less risk of hypoglycaemia and less weight gain than NPH insulin at comparable levels of glycaemic improvement in people with type 2 diabetes [abstract]. Diabetologia 2004; 47 Suppl. 1: A273-4
    • (2004) Diabetologia , vol.47 , Issue.SUPPL. 1
    • Hermansen, K.1    Derezinski, T.2    Kim, H.3
  • 74
    • 33947636649 scopus 로고    scopus 로고
    • Insulin detemir paimproves glycaemic control with less hypoglycaemia and no weight gain in patients with type 2 diabetes who were insulin naive or treated with NPH or insulin glargine: Clinical practice experience from a German subgroup of the PREDICTIVE study
    • Meneghini LF, Rosenberg KH, Koenen C, et al. Insulin detemir paimproves glycaemic control with less hypoglycaemia and no weight gain in patients with type 2 diabetes who were insulin naive or treated with NPH or insulin glargine: clinical practice experience from a German subgroup of the PREDICTIVE study. Diabetes Obes Metab 2007; 9: 418-27
    • (2007) Diabetes Obes Metab , vol.9 , pp. 418-427
    • Meneghini, L.F.1    Rosenberg, K.H.2    Koenen, C.3
  • 75
    • 6344284360 scopus 로고    scopus 로고
    • Fritsche A, Haring H. At last, a weight neutral insulin? Int J Obes Relat Metab Disord 2004; 28 Suppl. 2: S41-6
    • Fritsche A, Haring H. At last, a weight neutral insulin? Int J Obes Relat Metab Disord 2004; 28 Suppl. 2: S41-6
  • 76
    • 0033397302 scopus 로고    scopus 로고
    • Is continued weight gain inevitable in type 2 diabetes mellitus?
    • Tremble JM, Donaldson D. Is continued weight gain inevitable in type 2 diabetes mellitus? J R Soc Health 1999; 119: 235-9
    • (1999) J R Soc Health , vol.119 , pp. 235-239
    • Tremble, J.M.1    Donaldson, D.2
  • 77
    • 33144485704 scopus 로고    scopus 로고
    • The advantage of less weight gain increases with baseline obesity when insulin detemir rather than NPH insulin is added to oral agents in type 2 diabetes [abstract]
    • Hermansen K, Tamer SC. The advantage of less weight gain increases with baseline obesity when insulin detemir rather than NPH insulin is added to oral agents in type 2 diabetes [abstract]. Diabetes 2005; 54: A67
    • (2005) Diabetes , vol.54
    • Hermansen, K.1    Tamer, S.C.2
  • 78
    • 33947644686 scopus 로고    scopus 로고
    • No correlation between weight gain and number of hypoglycemic events in patients with type 2 diabetes treated with insulin detemir as compared to NPH insulin [abstract]
    • Davies M, Derezinski T, Kim H, et al. No correlation between weight gain and number of hypoglycemic events in patients with type 2 diabetes treated with insulin detemir as compared to NPH insulin [abstract]. Diabetes 2006; 55 Suppl. 1: A466
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Davies, M.1    Derezinski, T.2    Kim, H.3
  • 79
    • 6344222499 scopus 로고    scopus 로고
    • Benefits of insulin detemir over NPH insulin in children and adolescents with type 1 diabetes: Lower and more predictable fasting plasma glucose and lower risk of nocturnal hypoglycemia [abstract]
    • Robertson K, Schonle E, Gucev Z, et al. Benefits of insulin detemir over NPH insulin in children and adolescents with type 1 diabetes: lower and more predictable fasting plasma glucose and lower risk of nocturnal hypoglycemia [abstract]. Diabetes 2004; 53 Suppl. 2: A144
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 2
    • Robertson, K.1    Schonle, E.2    Gucev, Z.3
  • 81
    • 6344237010 scopus 로고    scopus 로고
    • Mathieu C. Can we reduce hypoglycaemia with insulin detemir? Int J Obes 2004; 28 (Suppl) 2: S35-40
    • Mathieu C. Can we reduce hypoglycaemia with insulin detemir? Int J Obes 2004; 28 (Suppl) 2: S35-40
  • 82
    • 33144490642 scopus 로고    scopus 로고
    • Insulin detemir reduces hypoglycemic risk at comparable HbA1c values compared to NPH insulin in patients with type 1 diabetes [abstract]
    • Heller S, Kim H. Insulin detemir reduces hypoglycemic risk at comparable HbA1c values compared to NPH insulin in patients with type 1 diabetes [abstract]. Diabetes 2005; 54 Suppl. 1: A120
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 1
    • Heller, S.1    Kim, H.2
  • 83
    • 24944502062 scopus 로고    scopus 로고
    • Lower risk of hypoglycemia with insulin detemir vs NPH insulin in elderly people with type 2 diabetes: A pooled analysis of phase 3 trials [abstract]
    • Garber AJ, Kim H, Santiago OM. Lower risk of hypoglycemia with insulin detemir vs NPH insulin in elderly people with type 2 diabetes: a pooled analysis of phase 3 trials [abstract]. Diabetes 2005; 54 Suppl. 1: A118
    • (2005) Diabetes , vol.54 , Issue.SUPPL. 1
    • Garber, A.J.1    Kim, H.2    Santiago, O.M.3
  • 84
    • 38049184050 scopus 로고    scopus 로고
    • Initiating insulin detemir improves glycemic control without weight gain in OAD-treated insulin naive patients with type 2 diabetes: Results from a German subgroup of the PREDICTIVE study [abstract]
    • Dornhorst A, Merilainen M, Ratzmann K-P. Initiating insulin detemir improves glycemic control without weight gain in OAD-treated insulin naive patients with type 2 diabetes: results from a German subgroup of the PREDICTIVE study [abstract]. Diabetes 2006; 55 Suppl. 1: A110
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Dornhorst, A.1    Merilainen, M.2    Ratzmann, K.-P.3
  • 85
    • 33845980702 scopus 로고    scopus 로고
    • Insulin detemir with or without OAD improves glycemic control and reduces hypoglycemic episodes, without weight gain, in type 2 diabetes patients previously treated with NPH or glargine: Results from a German subgroup of PREDICTIVE [abstract]
    • Dornhorst A, Merilainen M, Ratzmann K-P. Insulin detemir with or without OAD improves glycemic control and reduces hypoglycemic episodes, without weight gain, in type 2 diabetes patients previously treated with NPH or glargine: results from a German subgroup of PREDICTIVE [abstract]. Diabetes 2006; 55 Suppl. 1: A146
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Dornhorst, A.1    Merilainen, M.2    Ratzmann, K.-P.3
  • 86
    • 25644437034 scopus 로고    scopus 로고
    • Guerci B, Sauvanet JP. Subcutaneous insulin: pharmacokinetic variability and glycemic variability. Diabetes Metab 2005; 31: 4S7-24
    • Guerci B, Sauvanet JP. Subcutaneous insulin: pharmacokinetic variability and glycemic variability. Diabetes Metab 2005; 31: 4S7-24
  • 87
    • 14744276640 scopus 로고    scopus 로고
    • Reproducibility and variability in the action of injected insulin
    • Gin H, Hanaire-Broutin H. Reproducibility and variability in the action of injected insulin. Diabetes Metab 2005; 31: 7-13
    • (2005) Diabetes Metab , vol.31 , pp. 7-13
    • Gin, H.1    Hanaire-Broutin, H.2
  • 88
    • 25644451453 scopus 로고    scopus 로고
    • Within-person variation in fasting blood glucose is correlated to incidence of hypoglycaemia in people with type 1 diabetes treated with insulin detemir and NPH insulin [abstract]
    • Heller S, Kim H, Draeger E. Within-person variation in fasting blood glucose is correlated to incidence of hypoglycaemia in people with type 1 diabetes treated with insulin detemir and NPH insulin [abstract]. Diabetologia 2004; 47 Suppl. 1: A303
    • (2004) Diabetologia , vol.47 , Issue.SUPPL. 1
    • Heller, S.1    Kim, H.2    Draeger, E.3
  • 89
    • 35048827066 scopus 로고    scopus 로고
    • The usage of a simplified self-titration dosing guideline (303 Algorithm) for insulin detemir in patients with type 2 diabetes: Results of the randomized, controlled PREDICTIVE 303 study
    • Meneghini L, Koenen C, Weng W, et al. The usage of a simplified self-titration dosing guideline (303 Algorithm) for insulin detemir in patients with type 2 diabetes: results of the randomized, controlled PREDICTIVE 303 study. Diabetes Obes Metab 2007; 9: 902-13
    • (2007) Diabetes Obes Metab , vol.9 , pp. 902-913
    • Meneghini, L.1    Koenen, C.2    Weng, W.3
  • 90
    • 0033569317 scopus 로고    scopus 로고
    • Insulin delivery using pen devices: Simple-to-use tools may help young and old alike
    • Bohannon NJ. Insulin delivery using pen devices: simple-to-use tools may help young and old alike. Postgrad Med 1999; 106: 57-64, 68
    • (1999) Postgrad Med , vol.106 , Issue.57-64 , pp. 68
    • Bohannon, N.J.1
  • 91
    • 0344233275 scopus 로고    scopus 로고
    • A multicenter, randomized, open-label, comparative, two-period crossover trial of preference, efficacy, and safety profiles of a prefilled, disposable pen and conventional vial/syringe for insulin injection in patients with type 1 or 2 diabetes mellitus
    • Korytkowski M, Bell D, Jacobsen C, et al. A multicenter, randomized, open-label, comparative, two-period crossover trial of preference, efficacy, and safety profiles of a prefilled, disposable pen and conventional vial/syringe for insulin injection in patients with type 1 or 2 diabetes mellitus. Clin Ther 2003; 25: 2836-48
    • (2003) Clin Ther , vol.25 , pp. 2836-2848
    • Korytkowski, M.1    Bell, D.2    Jacobsen, C.3
  • 92
    • 0023916553 scopus 로고
    • Abnormal patterns of insulin secretion of non-insulin-dependent diabetes mellitus
    • Polonsky KS, Given BD, Hirsch LJ, et al. Abnormal patterns of insulin secretion of non-insulin-dependent diabetes mellitus. N Engl J Med 1988; 318: 1231-9
    • (1988) N Engl J Med , vol.318 , pp. 1231-1239
    • Polonsky, K.S.1    Given, B.D.2    Hirsch, L.J.3
  • 93
    • 26244459804 scopus 로고    scopus 로고
    • Pharmacokinetic and glucodynamic variability: Assessment of insulin glargine, NPH insulin and insulin ultralente in healthy volunteers using a euglycaemic clamp technique
    • Scholtz HE, Pretorius SG, Wessels DH, et al. Pharmacokinetic and glucodynamic variability: assessment of insulin glargine, NPH insulin and insulin ultralente in healthy volunteers using a euglycaemic clamp technique. Diabetologia 2005; 48: 1988-95
    • (2005) Diabetologia , vol.48 , pp. 1988-1995
    • Scholtz, H.E.1    Pretorius, S.G.2    Wessels, D.H.3
  • 94
    • 0034537104 scopus 로고    scopus 로고
    • Insulin aspart vs. human insulin rein the management of long-term blood glucose control in type 1 diabetes mellitus: A randomized controlled trial
    • Home PD, Lindholm A, Riis A. Insulin aspart vs. human insulin rein the management of long-term blood glucose control in type 1 diabetes mellitus: a randomized controlled trial. Diabet Med 2000; 17: 762-70
    • (2000) Diabet Med , vol.17 , pp. 762-770
    • Home, P.D.1    Lindholm, A.2    Riis, A.3
  • 95
    • 10044284096 scopus 로고    scopus 로고
    • Cost-effectiveness of detemir-based basal/bolus therapy versus NPH-based basal/bolus therapy for type 1 diabetes in a UK setting: An economic analysis based on meta-analysis results of four clinical trials
    • Palmer AJ, Roze S, Valentine WJ, et al. Cost-effectiveness of detemir-based basal/bolus therapy versus NPH-based basal/bolus therapy for type 1 diabetes in a UK setting: an economic analysis based on meta-analysis results of four clinical trials. Curr Med Res Opin 2004; 20: 1729-46
    • (2004) Curr Med Res Opin , vol.20 , pp. 1729-1746
    • Palmer, A.J.1    Roze, S.2    Valentine, W.J.3
  • 96
    • 34247398253 scopus 로고    scopus 로고
    • An economic assessment of analogue basal-bolus insulin versus human basal-bolus insulin in subjects with type 1 diabetes in the UK
    • Palmer AJ, Valentine WJ, Ray JA, et al. An economic assessment of analogue basal-bolus insulin versus human basal-bolus insulin in subjects with type 1 diabetes in the UK. Curr Med Res Opin 2007; 23: 895-901
    • (2007) Curr Med Res Opin , vol.23 , pp. 895-901
    • Palmer, A.J.1    Valentine, W.J.2    Ray, J.A.3
  • 97
    • 33745027233 scopus 로고    scopus 로고
    • Cost-effectiveness of basal insulin from a US health system perspective: Comparative analyses of detemir, glargine, and NPH
    • Valentine WJ, Palmer AJ, Erny-Albrecht KM, et al. Cost-effectiveness of basal insulin from a US health system perspective: comparative analyses of detemir, glargine, and NPH. Adv Ther 2006; 23: 191-207
    • (2006) Adv Ther , vol.23 , pp. 191-207
    • Valentine, W.J.1    Palmer, A.J.2    Erny-Albrecht, K.M.3
  • 98
    • 85036972320 scopus 로고    scopus 로고
    • Economic evaluation of therapy conversion in type 2 patients: Case-study of basal insulin [abstract]
    • Cobden D, Koenen C, Valentine W. Economic evaluation of therapy conversion in type 2 patients: case-study of basal insulin [abstract]. Diabetes 2006; 55 Suppl. 1: A550
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Cobden, D.1    Koenen, C.2    Valentine, W.3
  • 99
    • 85036984162 scopus 로고    scopus 로고
    • Initiating basal analog insulin among type 2 patients: Economic analysis of clinical experience [abstract]
    • Valentine W, Cobden D, Koenen C. Initiating basal analog insulin among type 2 patients: economic analysis of clinical experience [abstract]. Diabetes 2006; 55 Suppl. 1: A550-1
    • (2006) Diabetes , vol.55 , Issue.SUPPL. 1
    • Valentine, W.1    Cobden, D.2    Koenen, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.