Effect of fatty acids and selected drugs on the albumin binding of a long-acting, acylated insulin analogue

Journal of Pharmaceutical Sciences

Volumn 86, Issue 12, 1997, Pages 1365-1368

  Kurtzhals, Peter ^a   Havelund, Svend ^a   Jonassen, Ib ^a   Markussen, Jan ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALBUMIN; DIAZEPAM; FATTY ACID; GLIBENCLAMIDE; HUMAN SERUM ALBUMIN; IBUPROFEN; INSULIN DERIVATIVE; INSULIN DETEMIR; INSULIN[B29 LYSINE TETRADECANOYL DES B30]; OCTANOIC ACID; PHENYLBUTAZONE; TOLBUTAMIDE; UNCLASSIFIED DRUG; VALPROIC ACID; WARFARIN;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CONCENTRATION RESPONSE; DRUG PROTEIN BINDING; PROTEIN PROTEIN INTERACTION;

EID: 0031446132     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js9701768     Document Type: Article

References (27)

1. Markussen, J.; Hougaard, P.; Ribel, U; Sørensen, A. R.; Sørensen, E. Protein Engineering 1987, 1, 205-213.
2. Markussen, J.; Diers, I.; Engesgaard, A.; Hansen, M. T.; Hougaard, P.; Langkjaer, L.; Norris, K.; Ribel, U.; Sørensen A. R.; Sørensen, E.; Voigt, H. O. Protein Engineering 1987, 1, 215-223.
3. Markussen, J.; Diers, I.; Hougaard, P.; Langkjaer, L.; Norris, K.,; Snel, L.; Sørensen A. R.; Sørensen, E.; Voigt, H. O. Protein Engineering 1988, 2, 157-166.
4. Kurtzhals, P.; Kiehr, B.; Sørensen, A. J. Pharm. Sci. 1995, 84, 1164-1168.
5. Kurtzhals, P.; Ribel, U. Diabetes 1995, 44, 1381-1385.
6. Kurtzhals, P.; Havelund, S.; Jonassen, I.; Kiehr, B.; Larsen, U. D.; Ribel, U.; Markussen, J. Biochem. J. 1995, 312, 725-731.
7. Markussen, J.; Havelund, S.; Kurtzhals, P.; Andersen, A. S.; Halstrøm, J.; Hasselager, E.; Larsen, U. D.; Ribel, U.; Schäffer, L.; Vad, K.; Jonassen, I. Diabetologia, 1996, 39, 281-288.
8. Kurtzhals, P.; Havelund, S.; Jonassen, I.; Kiehr, B.; Ribel, U.; Markussen, J. J. Pharm. Sci. 1996, 85, 304-308.
9. He, X. M.; Carter, D. C. Science 1992, 358, 209-215.
10. Carter, D. C.; Ho, J. X. Adv. Protein Chem. 1994, 45, 153-203.
11. Sudlow, G.; Birkett, D. J.; Wade, D. N. Mol. Pharmacol. 1976, 12, 1052-1061.
12. Peters, T. All about Albumin. Biochemistry, Genetics and Medical Applications; Academic: San Diego, CA, 1996.
13. Havelund, S.; Halstrøm, J.; Jonassen, I.; Andersen, A. S.; Markussen, J. Acylated Insulin. Patent application PCT/DK94/ 00347. International Publication Number: WO 95/07931; 1995.
14. Drejer, K.; Kruse, V.; Larsen, U. D.; Hougaard, P.; Bjørn, S.; Gammeltoft, S. Diabetes 1991, 40, 1488-1495.
15. Reed, R. G.; Gates, T.; Peters, T. Anal. Biochem. 1975, 69, 361-371.
16. Sjöholm, I.; Ekman, B.; Kober, A.; Ljungstedt-Påhlman I.; Seiving, B.; Sjödin, T. Mol. Pharmacol. 1979, 16, 767-777.
17. Goodman Gilman A.; Rail, T. W.; Nies A. S., Taylor, P. The Pharmacological Basis of Therapeutics, 8th ed.; Pergamon: New York, 1990.
18. Groop, L. C. Diabetes Care 1992, 15, 737-754.
19. Fraze, E.; Donner, C. C.; Swislocki, A. L. M.; Chen, Y. D. I.; Reaven, G. M. J. Clin. Endocrinol. Metab. 1985, 61, 807-811.
20. Ganong, W. F. Review of Medical Physiology, 11th ed.; Lange Medical Publications: Los Altos, CA, 1983.
21. Spector, A. A. J. Lipid Res. 1975, 16, 165-179.
22. Hamilton-Wessler, M.; Ader, M.; Getty, L.; Markussen, J.; Bergman, R. N. Diabetologia 1996, 39 Suppl 1, A24.
23. Brown, J. R.; Shockley, P. In: Lipid-Protein Interactions; Jost, P. C.; Griffith, O. H., Eds.; Wiley: New York, 1982; pp 25-68.
24. Brown, K. F.; Crooks, M. J. Biochem. Pharmacol. 1976, 25, 1175-1178.
25. Gerich, J. E. N. Engl. J. Med. 1989, 321, 1231-1245.
26. Honore, B.; Brodersen, R. Mol. Pharmacol. 1984, 24, 137-150.
27. Brodersen, R.; Jørgensen, N.; Vorum, H.; Krukow, N. Mol. Pharmacol. 1990, 37, 704-709.