The role of organic cation transporter-3 in methamphetamine disposition and its behavioral response in rats

Brain Research

Volumn 1184, Issue 1, 2007, Pages 260-269

  Nakayama, Hironao ^a   Kitaichi, Kiyoyuki ^a,b   Ito, Yukiko ^a   Hashimoto, Katsunori ^a   Takagi, Kenji ^a   Yokoi, Toyoharu ^a   Takagi, Kenzo ^a   Ozaki, Norio ^c   Yamamoto, Tuneyuki ^b   Hasegawa, Takaaki ^d  

^a NAGOYA UNIVERSITY   (Japan)

^b NAGASAKI INTERNATIONAL UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Antisense; Behavioral sensitization; Dopamine; Drug transport; Methamphetamine; Organic cation transporter 3

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DOPAMINE; METHAMPHETAMINE; ORGANIC CATION TRANSPORTER 3;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; CEREBROSPINAL FLUID; CHOROID PLEXUS; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; DRUG DISPOSITION; DRUG PENETRATION; EXTRACELLULAR MATRIX; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM STIMULANTS; DOPAMINE; MALE; METHAMPHETAMINE; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; OLIGONUCLEOTIDES, ANTISENSE; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; PREFRONTAL CORTEX; RATS; RATS, WISTAR; TIME FACTORS;

RATTUS;

EID: 36348987970     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.09.072     Document Type: Article

References (43)

1. Ago Y., Nakamura S., Baba A., and Matsuda T. Sulpiride in combination with fluvoxamine increases in vivo dopamine release selectively in rat prefrontal cortex. Neuropsychopharmacology 30 (2005) 43-51
2. Amphoux A., Vialou V., Drescher E., Bruss M., Mannoury La Cour C., Rochat C., Millan M.J., Giros B., Bonisch H., and Gautron S. Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain. Neuropharmacology 50 (2006) 941-952
3. Aoyama N., Takahashi N., Kitaichi K., Ishihara R., Saito S., Maeno N., Ji X., Takagi K., Sekine Y., Iyo M., Harano M., Komiyama T., Yamada M., Sora I., Ujike H., Iwata N., Inada T., and Ozaki N. Association between gene polymorphisms of SLC22A3 and methamphetamine use disorder. Alcohol Clin. Exp. Res. 30 (2006) 1644-1649
4. Aston-Jones G., Chen S., Zhu Y., and Oshinsky M.L. A neural circuit for circadian regulation of arousal. Nat. Neurosci. 4 (2001) 732-738
5. Banks K.E., and Gratton A. Possible involvement of medial prefrontal cortex in amphetamine-induced sensitization of mesolimbic dopamine function. Eur. J. Pharmacol. 282 (1995) 157-167
6. Beurrier C., and Malenka R.C. Enhanced inhibition of synaptic transmission by dopamine in the nucleus accumbens during behavioral sensitization to cocaine. J. Neurosci. 22 (2002) 5817-5822
7. Beyer C.E., and Steketee J.D. Dopamine depletion in the medial prefrontal cortex induces sensitized-like behavioral and neurochemical responses to cocaine. Brain Res. 833 (1999) 133-141
8. Brady A.M., Glick S.D., and O'Donnell P. Selective disruption of nucleus accumbens gating mechanisms in rats behaviorally sensitized to methamphetamine. J. Neurosci. 25 (2005) 6687-6695
9. Cador M., Bjijou Y., Cailhol S., and Stinus L. d-amphetamine-induced behavioral sensitization: implication of a glutamatergic medial prefrontal cortex-ventral tegmental area innervation. Neuroscience 94 (1999) 705-721
10. Davidson C., Gow A.J., Lee T.H., and Ellinwood E.H. Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res. Brain Res. Rev. 36 (2001) 1-22
11. Di Chiara G., Bassareo V., Fenu S., De Luca M.A., Spina L., Cadoni C., Acquas E., Carboni E., Valentini V., and Lecca D. Dopamine and drug addiction: the nucleus accumbens shell connection. Neuropharmacology 47 Suppl 1 (2004) 227-241
12. Fujimoto Y., Kitaichi K., Nakayama H., Ito Y., Takagi K., Takagi K., and Hasegawa T. The pharmacokinetic properties of methamphetamine in rats with previous repeated exposure to methamphetamine: the differences between Long-Evans and Wistar rats. Exp. Anim. 56 (2007) 119-129
13. Gasser P.J., Lowry C.A., and Orchinik M. Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organic cation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J. Neurosci. 26 (2006) 8758-8766
14. Gentry W.B., Ghafoor A.U., Wessinger W.D., Laurenzana E.M., Hendrickson H.P., and Owens S.M. (+)-Methamphetamine-induced spontaneous behavior in rats depends on route of (+)METH administration. Pharmacol. Biochem. Behav. 79 (2004) 751-760
15. Graff C.L., and Pollack G.M. Drug transport at the blood-brain barrier and the choroid plexus. Curr. Drug Metab. 5 (2004) 95-108
16. Grundemann D., Babin-Ebell J., Martel F., Ording N., Schmidt A., and Schomig E. Primary structure and functional expression of the apical organic cation transporter from kidney epithelial LLC-PK1 cells. J. Biol. Chem. 272 (1997) 10408-10413
17. Grundemann D., Schechinger B., Rappold G.A., and Schomig E. Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter. Nat. Neurosci. 1 (1998) 349-351
18. Haag C., Berkels R., Grundemann D., Lazar A., Taubert D., and Schomig E. The localisation of the extraneuronal monoamine transporter (EMT) in rat brain. J. Neurochem. 88 (2004) 291-297
19. Kekuda R., Prasad P.D., Wu X., Wang H., Fei Y.J., Leibach F.H., and Ganapathy V. Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta. J. Biol. Chem. 273 (1998) 15971-15979
20. Kitaichi K., Fukuda M., Nakayama H., Aoyama N., Ito Y., Fujimoto Y., Takagi K., Takagi K., and Hasegawa T. Behavioral changes following antisense oligonucleotide-induced reduction of organic cation transporter-3 in mice. Neurosci. Lett. 382 (2005) 195-200
21. Kitaichi K., Morishita Y., Doi Y., Ueyama J., Matsushima M., Zhao Y.L., Takagi K., and Hasegawa T. Increased plasma concentration and brain penetration of methamphetamine in behaviorally sensitized rats. Eur. J. Pharmacol. 464 (2003) 39-48
22. Kusuhara H., and Sugiyama Y. Efflux transport systems for organic anions and cations at the blood-CSF barrier. Adv. Drug Deliv. Rev. 56 (2004) 1741-1763
23. Lowry C.A., Plant A., Shanks N., Ingram C.D., and Lightman S.L. Anatomical and functional evidence for a stress-responsive, monoamine-accumulating area in the dorsomedial hypothalamus of adult rat brain. Horm. Behav. 43 (2003) 254-262
24. Mendrek A., Blaha C.D., and Phillips A.G. Pre-exposure of rats to amphetamine sensitizes self-administration of this drug under a progressive ratio schedule. Psychopharmacology (Berl) 135 (1998) 416-422
25. Narita M., Akai H., Nagumo Y., Sunagawa N., Hasebe K., Nagase H., Kita T., Hara C., and Suzuki T. Implications of protein kinase C in the nucleus accumbens in the development of sensitization to methamphetamine in rats. Neuroscience 127 (2004) 941-948
26. Narita M., Akai H., Kita T., Nagumo Y., Narita M., Sunagawa N., Hara C., Hasebe K., Nagase H., and Suzuki T. Involvement of mitogen-stimulated p70-S6 kinase in the development of sensitization to the methamphetamine-induced rewarding effect in rats. Neuroscience 132 (2005) 553-560
27. Ogawa M., Suzuki H., Sawada Y., Hanano M., and Sugiyama Y. Kinetics of active efflux via choroid plexus of beta-lactam antibiotics from the CSF into the circulation. Am. J. Physiol. 266 (1994) R392-R399
28. Paterson I.A., Juorio A.V., and Boulton A.A. 2-Phenylethylamine: a modulator of catecholamine transmission in the mammalian central nervous system?. J. Neurochem. 55 (1990) 1827-1837
29. Paulson P.E., and Robinson T.E. Amphetamine-induced time-dependent sensitization of dopamine neurotransmission in the dorsal and ventral striatum: a microdialysis study in behaving rats. Synapse 19 (1995) 56-65
30. Paxinos G., and Watson D. The Rat Brain in Stereotaxic Coordinates (1997), Academic Press, New York
31. Pierce R.C., Reeder D.C., Hicks J., Morgan Z.R., and Kalivas P.W. Ibotenic acid lesions of the dorsal prefrontal cortex disrupt the expression of behavioral sensitization to cocaine. Neuroscience 82 (1998) 1103-1114
32. Riviere G.J., Gentry W.B., and Owens S.M. Disposition of methamphetamine and its metabolite amphetamine in brain and other tissues in rats after intravenous administration. J. Pharmacol. Exp. Ther. 292 (2000) 1042-1047
33. Schildkraut J.J., and Mooney J.J. Toward a rapidly acting antidepressant: the normetanephrine and extraneuronal monoamine transporter (uptake 2) hypothesis. Am. J. Psychiatry 161 (2004) 909-911
34. Shoblock J.R., Maisonneuve I.M., and Glick S.D. Differential interactions of desipramine with amphetamine and methamphetamine: evidence that amphetamine releases dopamine from noradrenergic neurons in the medial prefrontal cortex. Neurochem. Res. 29 (2004) 1437-1442
35. Shoblock J.R., Sullivan E.B., Maisonneuve I.M., and Glick S.D. Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats. Psychopharmacology (Berl) 65 (2003) 359-369
36. Szumlinski K.K., Balogun M.Y., Maisonneuve I.M., and Glick S.D. Interactions between iboga agents and methamphetamine sensitization: studies of locomotion and stereotypy in rats. Psychopharmacology (Berl) 151 (2000) 234-241
37. Takeda H., Inazu M., and Matsumiya T. Astroglial dopamine transport is mediated by norepinephrine transporter. Naunyn-Schmiedebergs Arch. Pharmakol. 366 (2002) 620-623
38. Vanderschuren L.J., Schmidt E.D., De Vries T.J., Van Moorsel C.A., Tilders F.J., and Schoffelmeer A.N. A single exposure to amphetamine is sufficient to induce long-term behavioral, neuroendocrine, and neurochemical sensitization in rats. J. Neurosci. 19 (1999) 9579-9586
39. Vialou V., Amphoux A., Zwart R., Giros B., and Gautron S. Organic cation transporter 3 (Slc22a3) is implicated in salt-intake regulation. J. Neurosci. 24 (2004) 2846-2851
40. Wallace T.L., Gudelsky G.A., and Vorhees C.V. Methamphetamineinduced neurotoxicity alters locomotor activity, stereotypic behavior, and stimulated dopamine release in the rat. J. Neurosci. 19 (1999) 9141-9148
41. Wolf M.E., White F.J., and Hu X.T. MK801 prevents alterations in the mesoaccumbens dopamine system associated with behavioral sensitization to amphetamine. J. Neurosci. 14 (1994) 1735-1745
42. Wu X., Kekuda R., Huang W., Fei Y.J., Leibach F.H., Chen J., Conway S.J., and Ganapathy V. Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain. J. Biol. Chem. 273 (1998) 32776-32786
43. Zametkin A.J., Brown G.L., Karoum F., Rapoport J.L., Langer D.H., Chuang L.W., and Wyatt R.J. Urinary phenethylamine response to d-amphetamine in 12 boys with attention deficit disorder. Am. J. Psychiatry 141 (1984) 1055-1058