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Volumn 34, Issue 3, 1999, Pages 376-377

Prolyl 4-hydroxylase inhibitor (HOE 077) prevents TIMP-1 gene expression in rat liver fibrosis

Author keywords

Procollagen; Prolyl 4 hydroxylase inhibitor; Tissue inhibitor of metalloproteinase 1 (TIMP 1)

Indexed keywords

COLLAGEN TYPE 1; HYDROXYPROLINE; LUFIRONIL; MESSENGER RNA; OXYGENASE INHIBITOR; PROCOLLAGEN; PROLINE; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

EID: 0032810213     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350050277     Document Type: Article
Times cited : (32)

References (8)
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  • 2
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    • Prolyl 4-hydroxylase, a target enzyme for drug development: Design of suppressive agents and the in vitro effects of inhibitors and proinhibitors
    • Hanauske-Abel HM. Prolyl 4-hydroxylase, a target enzyme for drug development: Design of suppressive agents and the in vitro effects of inhibitors and proinhibitors, J Hepatol 1991;13(Suppl 3):S8-S16.
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    • Prolyl 4-hydroxylase and its role in collagen synthesis
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    • (1991) J Hepato , vol.13 , Issue.SUPPL. 3
    • Pilajaniemi, T.1    Myllya, R.2    Kivirikko, K.3
  • 5
    • 0029923670 scopus 로고    scopus 로고
    • The prolyl 4-hydroxylase inhibitor HOE 077 prevents activation of Ito cells, reducing procollagen gene expression in rat liver fibrosis induced by choline-deficient L-amino acid-defined diet
    • Sakaida I, Matsumura Y, Kubota M, Kayano K, Takenaka K, Okita K. The prolyl 4-hydroxylase inhibitor HOE 077 prevents activation of Ito cells, reducing procollagen gene expression in rat liver fibrosis induced by choline-deficient L-amino acid-defined diet. Hepatology 1996;23:755-63.
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  • 6
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    • The cellular basis of hepatic fibrosis: Mechanisms and treatment strategies
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    • Tissue inhibitor of metalloproteinase-1 messenger rna expression is enhanced relative to interstitial collagenase messenger rna in experimental liver injury and fibrosis
    • Iredale JP, Benyon C, Arthur MJP, Ferris WF, Alcolado R, Winwood PJ, et al. Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis. Hepatology 1996;24:176-84.
    • (1996) Hepatology , vol.24 , pp. 176-184
    • Iredale, J.P.1    Benyon, C.2    Arthur, M.J.P.3    Ferris, W.F.4    Alcolado, R.5    Winwood, P.J.6
  • 8
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    • Evidence for pretranslational regulation of collagen synthesis by procollagen propeptides
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.