Modeling the effect of blood glucose and physical exercise on plasma adrenaline in people with type 1 diabetes

Diabetes Technology and Therapeutics

Volumn 9, Issue 6, 2007, Pages 501-507

  Kildegaard, Jonas ^a   Christensen, Toke Folke ^a   Johansen, Mette Dencker ^a   Randløv, Jette ^b   Hejlesen, Ole K ^a  

^a AALBORG UNIVERSITY   (Denmark)

^b NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; GLUCOSE;

ADRENALIN BLOOD LEVEL; ADRENALIN RELEASE; ARTICLE; COMPARTMENT MODEL; EXERCISE; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; INFUSION; INSULIN DEPENDENT DIABETES MELLITUS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; REGRESSION ANALYSIS;

BLOOD GLUCOSE; COMPUTER SIMULATION; DIABETES MELLITUS, TYPE 1; EPINEPHRINE; EXERCISE; HUMANS; HYPOGLYCEMIA; MODELS, BIOLOGICAL;

EID: 36348975811     PISSN: 15209156     EISSN: None     Source Type: Journal    
DOI: 10.1089/dia.2007.0242     Document Type: Article

References (33)

1. Hoffman RP: Antecedent hypoglycemia does not alter increased epinephrine-induced lipolysis in type 1 diabetes mellitus. Metabolism 2006;55:371-380.
2. Robertson RP, Sutherland DE, Seaquist ER, Lanz KJ: Glucagon, catecholamine, and symptom responses to hypoglycemia in living donors of pancreas segments. Diabetes 2003;52:1689-1694.
3. Watt MJ, Howlett KF, Febbraio MA, Spriet LL, Hargreaves M: Adrenaline increases skeletal muscle glycogenolysis, pyruvate dehydrogenase activation and carbohydrate oxidation during moderate exercise in humans. J Physiol 2001;534:269-278.
4. Wortsman J: Role of epinephrine in acute stress. Endocrinol Metab Clin North Am 2002;31:79-106.
5. Forster CD, Macdonald IA: The assay of the catecholamine content of small volumes of human plasma. Biomed Chromatogr 1999;13:209-215.
6. Westermann J, Hubl W, Kaiser N, Salewski L: Simple, rapid and sensitive determination of epinephrine and norepinephrine in urine and plasma by non-competitive enzyme immunoassay, compared with HPLC method. Clin Lab 2002;48:61-71.
7. Hjemdahl P: Plasma catecholamines - analytical challenges and physiological limitations. Baillieres Clin Endocrinol Metab 1993;7:307-353.
8. Ueyama J, Kitaichi K, Iwase M, Takagi K, Takagi K, Hasegawa T: Application of ultrafiltration method to measurement of catecholamines in plasma of human and rodents by high-performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 2003;798:35-41.
9. Blewis ME, Nugent-Derfus GE, Schmidt TA, Schumacher BL, Sah RL: A model of synovial fluid lubricant composition in normal and injured joints. Eur Cells Mater 2007;13:26-39.
10. Cobelli C, Saccomani MP, Ferrannini E, DeFronzo RA, Gelfand R, Bonadonna R: A compartmental model to quantitate in vivo glucose transport in the human forearm. Am J Physiol 1989;257:E943-E958.
11. Hack CE, Chiu WA, Jay ZQ, Clewell HJ: Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites. Regul Toxicol Pharmacol 2006;46:63-83.
12. Bronzino JD, ed.: Biomedical Engineering Fundamentals. Boca Raton, FL: CRC Press, 2006.
13. Dejgaard A, Hilsted J, Henriksen JH, Christensen NJ: Plasma adrenaline kinetics in type 1 (insulin-dependent) diabetic patients with and without autonomic neuropathy. Diabetologia 1989;32:810-813.
14. Brown SA, Lipschitz AH, Kenkel JM, Sorokin E, Shepherd G, Grebe S, Oliver LK, Luby M, Rohrich RJ: Pharmacokinetics and safety of epinephrine use in liposuction. Plastic Reconstr Surg 2004;114:756-763.
15. Esler M, Eisenhofer G, Chin J, Jennings G, Meredith I, Cox H, Lambert G, Thompson J, Dart A: Is adrenaline released by sympathetic nerves in man? Clin Auton Res 1991;1:103-108.
16. Proctor DN, O'Brien PC, Atkinson EJ, Nair KS: Comparison of techniques to estimate total body skeletal muscle mass in people of different age groups. Am J Physiol 1999;277:E489-E495.
17. Mitrakou A, Ryan C, Veneman T, Mokan M, Jenssen T, Kiss I, Durrant J, Cryer P, Gerich J: Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction. Am J Physiol 1991;260:E67-E74.
18. Fanelli C, Pampanelli S, Epifano L, Rambotti AM, Ciofetta M, Modarelli F, Divincenzo A, Annibale B, Lepore M, Lalli C, Delsindaco P, Brunetti P, Bolli GB: Relative roles of insulin and hypoglycemia on induction of neuroendocrine responses to, symptoms of, and deterioration of cognitive function in hypoglycemia in male and female humans. Diabetologia 1994;37:797-807.
19. De Feo P, Perriello G, De Cosmo S, Ventura MM, Campbell PJ, Brunetti P, Gerich JE, Bolli GB: Comparison of glucose counterregulation during shortterm and prolonged hypoglycemia in normal humans. Diabetes 1986;35:563-569.
20. Dagogo-Jack SE, Craft S, Cryer PE: Hypoglycemia-associated autonomic failure in insulin-dependent diabetes mellitus. Recent antecedent hypoglycemia reduces autonomic responses to, symptoms of, and defense against subsequent hypoglycemia. J Clin Invest 1993;91:819-828.
21. Fruehwald-Schultes B, Born J, Kern W, Peters A, Fehm HL: Adaptation at cognitive function to hypoglycemia in healthy men. Diabetes Care 2000;23:1059-1066.
22. Mitrakou A, Fanelli C, Veneman T, Perriello G, Calderone S, Platanisiotis D, Rambotti A, Raptis S, Brunetti P, Cryer P, et al.: Reversibility of unawareness of hypoglycemia in patients with insulinomas. N Engl J Med 1993;329:834-839.
23. Levy CJ, Kinsley BT, Bajaj M, Simonson DC: Effect of glycemic control on glucose counterregulation during hypoglycemia in NIDDM. Diabetes Care 1998;21:1330-1338.
24. DeLean A, Munson PJ, Rodbard D: Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. Am J Physiol 1978;235:E97-E102.
25. Ahlborg G, Felig P, Hagenfeldt L, Hendler R, Wahren J: Substrate turnover during prolonged exercise in man. Splanchnic and leg metabolism of glucose, free fatty acids, and amino acids. J Clin Invest 1974;53:1080-1090.
26. Wahren J, Felig P, Ahlborg G, Jorfeldt L: Glucose metabolism during leg exercise in man. J Clin Invest 1971;50:2715-2725.
27. th IFAC World Congress on Automatic Control, Barcelona, Spain, 2002.
28. Guy DA, Sandoval D, Richardson MA, Tate D, Flakoll PJ, Davis SN: Differing physiological effects of epinephrine in type 1 diabetes and nondiabetic humans. Am J Physiol Endocrinol Metab 2005;288:E178-E186.
29. Vicini P, Avogaro A, Spilker ME, Gallo A, Cobelli C: Epinephrine effects on insulin-glucose dynamics: the labeled IVGTT two-compartment minimal model approach. A J Physiol Endocrinol Metab 2002;283:E78-E84.
30. Vranic M, Miles P, Rastogi K, Yamatani K, Shi Z, Lickley L, Hetenyi G: Effect of stress on glucoregulation in physiology and diabetes. Adv Exp Med Biol 1991;291:161-183.
31. De-Vries WR, Bernards NT, de-Rooij MH, Koppeschaar HP: Dynamic exercise discloses different timerelated responses in stress hormones. Psychosom Med 2000;62:866-872.
32. Guelfi KJ, Jones TW, Fournier PA: The decline in blood glucose levels is less with intermittent high-intensity compared with moderate exercise in individuals with type 1 diabetes. Diabetes Care 2005;28:1289-1294.
33. Heyward VH: The Physical Fitness Specialist Certification Manual. Dallas: The Cooper Institute for Aerobics Research, 1997:48.