-
1
-
-
0346458886
-
Overview of phase I studies of intravenous administration of PV701, an oncolytic virus
-
Lorence RM, Pecora AL, Major PP, Hotte SJ, Laurie SA, Roberts MS et al. Overview of phase I studies of intravenous administration of PV701, an oncolytic virus. Curr Opin Mol Ther 2003; 5: 618-624.
-
(2003)
Curr Opin Mol Ther
, vol.5
, pp. 618-624
-
-
Lorence, R.M.1
Pecora, A.L.2
Major, P.P.3
Hotte, S.J.4
Laurie, S.A.5
Roberts, M.S.6
-
2
-
-
0032897339
-
Human tumor cell modification by virus infection: An efficient and safe way to produce cancer vaccine with pleiotropic immune stimulatory properties when using Newcastle Disease Virus
-
Schirrmacher V, Haas C, Bonifer R, Ahlert T, Gerhards R, Ertel C. Human tumor cell modification by virus infection: An efficient and safe way to produce cancer vaccine with pleiotropic immune stimulatory properties when using Newcastle Disease Virus. Gene Therapy 1999; 6: 63-73.
-
(1999)
Gene Therapy
, vol.6
, pp. 63-73
-
-
Schirrmacher, V.1
Haas, C.2
Bonifer, R.3
Ahlert, T.4
Gerhards, R.5
Ertel, C.6
-
3
-
-
0033955837
-
Newcastle Disease Virus (NDW brief history of its oncolytic strains
-
Sinkovics JG, Horvath JC. Newcastle Disease Virus (NDW brief history of its oncolytic strains. J Clin Virol 2000; 16: 1-15.
-
(2000)
J Clin Virol
, vol.16
, pp. 1-15
-
-
Sinkovics, J.G.1
Horvath, J.C.2
-
4
-
-
0035139983
-
Danger signals: SOS to the immune system
-
Gallucci S, Matzinger P. Danger signals: SOS to the immune system. Curr Opin Immunol 2001; 13: 114-119.
-
(2001)
Curr Opin Immunol
, vol.13
, pp. 114-119
-
-
Gallucci, S.1
Matzinger, P.2
-
5
-
-
0036302403
-
Induction of interferon α, and tumor necrosis factor-related apoptosis-inducing blood mononuclear cells by hemagglutinin-neuraminidase but not F protein of Newcastle Disease Virus
-
Zeng J, Fournier P, Schirrmacher V. Induction of interferon α, and tumor necrosis factor-related apoptosis-inducing blood mononuclear cells by hemagglutinin-neuraminidase but not F protein of Newcastle Disease Virus. Virology 2002; 297: 19-30.
-
(2002)
Virology
, vol.297
, pp. 19-30
-
-
Zeng, J.1
Fournier, P.2
Schirrmacher, V.3
-
6
-
-
0348080082
-
Two ways to induce innate immune responses in human PBMCs: Paracrine stimulation of IFN-α responses by viral protein or dsRNA
-
Fournier P, Zeng J, Schirrmacher V. Two ways to induce innate immune responses in human PBMCs: Paracrine stimulation of IFN-α responses by viral protein or dsRNA. Int J Oncol 2003; 23: 673-680.
-
(2003)
Int J Oncol
, vol.23
, pp. 673-680
-
-
Fournier, P.1
Zeng, J.2
Schirrmacher, V.3
-
7
-
-
22544455673
-
-
Káto H, Sato S, Yoneyama M, Yamamoto M, Uematsu 5, Akira.S et al. Cell type-specific involvement of RIG-I in antiviral response. Immunity 2005; 23: 19-28.
-
Káto H, Sato S, Yoneyama M, Yamamoto M, Uematsu 5, Akira.S et al. Cell type-specific involvement of RIG-I in antiviral response. Immunity 2005; 23: 19-28.
-
-
-
-
8
-
-
0030725442
-
The double-stranded RNA-dependent protein kinase PKR: Structure and function
-
Clemens MJ, Elia A. The double-stranded RNA-dependent protein kinase PKR: Structure and function. J Interferon Cytokine Res 1997; 17 503-524.
-
(1997)
J Interferon Cytokine Res
, vol.17
, pp. 503-524
-
-
Clemens, M.J.1
Elia, A.2
-
9
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4: 499-511.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
10
-
-
0022611296
-
Prevention of metastatic spread by postoperative immunotherapy with virally modified autologous tumor cells. I: Parameters for optimal therapeutic effects
-
Heicappell R, Schirrmacher V, von Hoegen P, Ahlert T, Appelhans B. Prevention of metastatic spread by postoperative immunotherapy with virally modified autologous tumor cells. I: Parameters for optimal therapeutic effects. Int J Cancer 1986; 37: 569.
-
(1986)
Int J Cancer
, vol.37
, pp. 569
-
-
Heicappell, R.1
Schirrmacher, V.2
von Hoegen, P.3
Ahlert, T.4
Appelhans, B.5
-
11
-
-
0023261148
-
Prevention of metastatic spread by postoperative immunotherapy with virally modified autologous tumor cells. II: Establishment of specific systemic anti tumor immunity
-
Schirrmacher V, Heicappell R. Prevention of metastatic spread by postoperative immunotherapy with virally modified autologous tumor cells. II: Establishment of specific systemic anti tumor immunity. Clin Exptl Met 1987; 5: 147-156.
-
(1987)
Clin Exptl Met
, vol.5
, pp. 147-156
-
-
Schirrmacher, V.1
Heicappell, R.2
-
12
-
-
0036654058
-
Human tumor cell infection by Newcastle. Disease Virus leads to upregulation of HLA and cell adhesion molecules and to induction of interferons, chemokines and finally apoptosis
-
Washburn B, Schirrmacher V. Human tumor cell infection by Newcastle. Disease Virus leads to upregulation of HLA and cell adhesion molecules and to induction of interferons, chemokines and finally apoptosis. Int J Oncol 2002; 21: 85-93.
-
(2002)
Int J Oncol
, vol.21
, pp. 85-93
-
-
Washburn, B.1
Schirrmacher, V.2
-
13
-
-
16544392098
-
Anti-tumor vaccination of patiens with glioblastoma. nultiforme in a case-control study: Feasibility, safety and clinical benefit
-
Steiner HH, Bonsanto MM, Beckhove P, Brysch M, Geletneky K, Ahmadi R et al. Anti-tumor vaccination of patiens with glioblastoma. nultiforme in a case-control study: Feasibility, safety and clinical benefit. J Clin Oncol 2004; 22: 4272-4281.
-
(2004)
J Clin Oncol
, vol.22
, pp. 4272-4281
-
-
Steiner, H.H.1
Bonsanto, M.M.2
Beckhove, P.3
Brysch, M.4
Geletneky, K.5
Ahmadi, R.6
-
14
-
-
7444229927
-
Anti-tumor vaccination with HNSCC with autologous virus-modified tumor cells
-
Karcher J, Dyckhoff G, Beckhove P, Reisser C, Brysch M, Zionta Y et al. Anti-tumor vaccination with HNSCC with autologous virus-modified tumor cells. Cancer res 2004, 64: 8057-8061.
-
(2004)
Cancer res
, vol.64
, pp. 8057-8061
-
-
Karcher, J.1
Dyckhoff, G.2
Beckhove, P.3
Reisser, C.4
Brysch, M.5
Zionta, Y.6
-
15
-
-
0032993642
-
Rescue of Newcastle Disease Virus from cloned cDNA: Evidence that cleavability of the fusion protein is a major determinant for virulence
-
Peeters BP, de Leeuw OS, Koch G, Gielkens AL. Rescue of Newcastle Disease Virus from cloned cDNA: Evidence that cleavability of the fusion protein is a major determinant for virulence. J Virol 1999; 73 5001-5009.
-
(1999)
J Virol
, vol.73
, pp. 5001-5009
-
-
Peeters, B.P.1
de Leeuw, O.S.2
Koch, G.3
Gielkens, A.L.4
-
16
-
-
18144363557
-
Clinical trials of antitumor vaccination with an autologous tumor cell vaccine modified by virus infection: Improvement of patient survival based on improved anti-tumor immune memory
-
Schirrmacher V. Clinical trials of antitumor vaccination with an autologous tumor cell vaccine modified by virus infection: Improvement of patient survival based on improved anti-tumor immune memory. Cancer Immunol Immunother. 2005; 54: 587-598.
-
(2005)
Cancer Immunol Immunother
, vol.54
, pp. 587-598
-
-
Schirrmacher, V.1
-
17
-
-
0037385304
-
Recombinant Newcastle disease virus as a viral vector: Effect of genomic, location of foreign gene on gene expression and virus replication
-
Zhao H, Peeters BPH. Recombinant Newcastle disease virus as a viral vector: Effect of genomic, location of foreign gene on gene expression and virus replication. J Gen Virol 2003; 84: 781-788.
-
(2003)
J Gen Virol
, vol.84
, pp. 781-788
-
-
Zhao, H.1
Peeters, B.P.H.2
-
18
-
-
30444435731
-
A tumor vaccine containing anti-CD3 and anti-CD28 bispecific antibodies triggers strong and durable anti-tumor activity in human lymphocytes
-
Haas C, Lulei M, Fournier P, Arnold A, Schirrimacher V. A tumor vaccine containing anti-CD3 and anti-CD28 bispecific antibodies triggers strong and durable anti-tumor activity in human lymphocytes. Int J Cancer 2005; 118: 658-667.
-
(2005)
Int J Cancer
, vol.118
, pp. 658-667
-
-
Haas, C.1
Lulei, M.2
Fournier, P.3
Arnold, A.4
Schirrimacher, V.5
-
19
-
-
0035905321
-
BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction
-
Dzionek A, Sohma Y, Nagafune J, Cella M, Colonna M, Facchetti F et al. BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction. J Exp Med 2001; 194: 1823-1834.
-
(2001)
J Exp Med
, vol.194
, pp. 1823-1834
-
-
Dzionek, A.1
Sohma, Y.2
Nagafune, J.3
Cella, M.4
Colonna, M.5
Facchetti, F.6
-
20
-
-
0030857817
-
Virus potentiation of tumor vaccine T-cell stimulatory capacity requires cell surface binding but not infection
-
Schirrmacher V, Haas. C, Bonifer R, Ertel C. Virus potentiation of tumor vaccine T-cell stimulatory capacity requires cell surface binding but not infection. Clin Cancer Res 1997; 3: 1135-1148.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 1135-1148
-
-
Schirrmacher, V.1
Haas, C.2
Bonifer, R.3
Ertel, C.4
-
21
-
-
33646860113
-
Technical hurdles in a pilot clinical trial of combined B7-2 and GM-CSF immunogene therapy for glioblastomas and melanomas
-
Parney IF, Chang LJ, Farr-Jones MA, Hao C, Smylie M, Petruk KC. Technical hurdles in a pilot clinical trial of combined B7-2 and GM-CSF immunogene therapy for glioblastomas and melanomas. J Neurooncol 2006; 78: 71-80.
-
(2006)
J Neurooncol
, vol.78
, pp. 71-80
-
-
Parney, I.F.1
Chang, L.J.2
Farr-Jones, M.A.3
Hao, C.4
Smylie, M.5
Petruk, K.C.6
-
22
-
-
0037349751
-
Application of autologous tumor cell vaccine and NDV vaccine in treatment of tumors of digestive tract
-
Liang W, Wang H, Sun TM, Yao WQ Chen LL, Jin Y et al. Application of autologous tumor cell vaccine and NDV vaccine in treatment of tumors of digestive tract. World J Gastroenterol 2003; 9: 495-498.
-
(2003)
World J Gastroenterol
, vol.9
, pp. 495-498
-
-
Liang, W.1
Wang, H.2
Sun, T.M.3
Yao, W.Q.4
Chen, L.L.5
Jin, Y.6
-
23
-
-
33745206950
-
Tumor selective replication of Newcastle Disease Virus: Association with defects of tumor cells in anti-viral defence
-
Fiola C, Peeters B, Fournier P, Arnold A, Bucur M, Schirrmacher V. Tumor selective replication of Newcastle Disease Virus: Association with defects of tumor cells in anti-viral defence. Int J Cancer 2006; 119: 328-358.
-
(2006)
Int J Cancer
, vol.119
, pp. 328-358
-
-
Fiola, C.1
Peeters, B.2
Fournier, P.3
Arnold, A.4
Bucur, M.5
Schirrmacher, V.6
-
24
-
-
0037427785
-
Apoptotic, but not necrotic, tumor cell vaccines induce a potent immune response. in vivo
-
Scheffer SR, Nave H, Korańgy F, Schlote K, Pabst R, Jaffee EM et al. Apoptotic, but not necrotic, tumor cell vaccines induce a potent immune response. in vivo. Int J Cancer 2003; 103: 205-211.
-
(2003)
Int J Cancer
, vol.103
, pp. 205-211
-
-
Scheffer, S.R.1
Nave, H.2
Korańgy, F.3
Schlote, K.4
Pabst, R.5
Jaffee, E.M.6
-
25
-
-
0141576738
-
Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients, with metastatic melanoma
-
Soiffer R, Hodi FS, Haluska F, Jung K, Gillessen S, Singer S et al. Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients, with metastatic melanoma. J Clin Oncol 2003; 21: 3343-3350.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3343-3350
-
-
Soiffer, R.1
Hodi, F.S.2
Haluska, F.3
Jung, K.4
Gillessen, S.5
Singer, S.6
-
26
-
-
0029129319
-
Use of murine models of cytokine-secreting tumor vaccines to study feasibility and toxicity issues critical to designing clinical trials
-
Jaffee EM, Lazenby A, Meurer J, Marshall F, Hauda KM, Counts C et al. Use of murine models of cytokine-secreting tumor vaccines to study feasibility and toxicity issues critical to designing clinical trials. J Immunother Emphasis Tumor Immunol 1995; 18: 1-9.
-
(1995)
J Immunother Emphasis Tumor Immunol
, vol.18
, pp. 1-9
-
-
Jaffee, E.M.1
Lazenby, A.2
Meurer, J.3
Marshall, F.4
Hauda, K.M.5
Counts, C.6
-
27
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secret murine granulocyt-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
-
Dranoff G, Jaffee E, Lazenby A, Golumbek P, Pardoll D, Mulligan RC et al. Vaccination with irradiated tumor cells engineered to secret murine granulocyt-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA 1993; 90: 3539-3543.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3539-3543
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
Golumbek, P.4
Pardoll, D.5
Mulligan, R.C.6
-
28
-
-
8544280001
-
Highly successful therapeutic vaccination combining dendritic cells and tumor cells secreting granulocyte macrophage colony-stimulating factor
-
Driessens G, Hamdane M, Cool V, Velu T, Bruyns C. Highly successful therapeutic vaccination combining dendritic cells and tumor cells secreting granulocyte macrophage colony-stimulating factor. Cancer Res 2004; 64: 8435-8442.
-
(2004)
Cancer Res
, vol.64
, pp. 8435-8442
-
-
Driessens, G.1
Hamdane, M.2
Cool, V.3
Velu, T.4
Bruyns, C.5
-
29
-
-
33644813226
-
Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients
-
Luiten RM, Kueter EW, Mooi W, Gallee MP, Rankin EM, Gerritsen WR et al. Immunogenicity, including vitiligo, and feasibility of vaccination with autologous GM-CSF-transduced tumor cells in metastatic melanoma patients. J Clin Oncol 2005; 23: 8978-8991.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8978-8991
-
-
Luiten, R.M.1
Kueter, E.W.2
Mooi, W.3
Gallee, M.P.4
Rankin, E.M.5
Gerritsen, W.R.6
-
30
-
-
33748355822
-
Objective clinical regression of metastatic breast cancer in disparate sites after use of whole-cell vaccine genetically modified to release sargramostim
-
Wiseman CL, Kharazi A. Objective clinical regression of metastatic breast cancer in disparate sites after use of whole-cell vaccine genetically modified to release sargramostim. Breast J 2006; 12 475-480.
-
(2006)
Breast J
, vol.12
, pp. 475-480
-
-
Wiseman, C.L.1
Kharazi, A.2
-
31
-
-
0030007925
-
Construction of recombinant vaccinia virus expressing GM-CSF and its use as tumor vaccine
-
Qin HX, Chatterjee SK. Construction of recombinant vaccinia virus expressing GM-CSF and its use as tumor vaccine. Gene Therapy 1996; 3: 59-66.
-
(1996)
Gene Therapy
, vol.3
, pp. 59-66
-
-
Qin, H.X.1
Chatterjee, S.K.2
-
33
-
-
33748455338
-
Type I interferons in host defense
-
Stetson DB, Medzhitov R. Type I interferons in host defense. Immunity 2006; 25: 373-381.
-
(2006)
Immunity
, vol.25
, pp. 373-381
-
-
Stetson, D.B.1
Medzhitov, R.2
-
34
-
-
0032544067
-
CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma
-
Hurwitz AA, Yu TF, Leach DR, Allison JP. CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma. Proc Natl Acad Sci USA 1998; 95: 10067-10071.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 10067-10071
-
-
Hurwitz, A.A.1
Yu, T.F.2
Leach, D.R.3
Allison, J.P.4
-
35
-
-
33845343558
-
Vascular endothelial growth factor blockade reduces intratumoral regulatory t cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy
-
Li B, Lalani AS, Harding TC, Luan B, Koprivnikar K, Huan Tu G et al. Vascular endothelial growth factor blockade reduces intratumoral regulatory t cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy. Clin Cancer Res 2006; 12: 6808-6816.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6808-6816
-
-
Li, B.1
Lalani, A.S.2
Harding, T.C.3
Luan, B.4
Koprivnikar, K.5
Huan, T.G.6
-
36
-
-
0035328683
-
Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophagecolony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice
-
Machiels JP, Reilly RT, Emens LA, Ercolini AM, Lei RY, Weintraub D et al. Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophagecolony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice. Cancer Res 2001; 61: 3689-3697.
-
(2001)
Cancer Res
, vol.61
, pp. 3689-3697
-
-
Machiels, J.P.1
Reilly, R.T.2
Emens, L.A.3
Ercolini, A.M.4
Lei, R.Y.5
Weintraub, D.6
-
37
-
-
16844386543
-
Administration of IFN-α enhances the efficacy of a granulocyte macrophage colony stimulating factor-secreting tumor cell vaccine
-
Prell RA, Li B, Lin JM, VanRoey M, Jooss K. Administration of IFN-α enhances the efficacy of a granulocyte macrophage colony stimulating factor-secreting tumor cell vaccine. Cancer Res 2005, 65: 2449-2456.
-
(2005)
Cancer Res
, vol.65
, pp. 2449-2456
-
-
Prell, R.A.1
Li, B.2
Lin, J.M.3
VanRoey, M.4
Jooss, K.5
-
38
-
-
0037441854
-
TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus
-
Washburn B, Weigand MA, Grosse-Wilde A, Janke M, Stahl H, Rieser E et al. TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus. J Immunol 2003; 170: 1814-1821.
-
(2003)
J Immunol
, vol.170
, pp. 1814-1821
-
-
Washburn, B.1
Weigand, M.A.2
Grosse-Wilde, A.3
Janke, M.4
Stahl, H.5
Rieser, E.6
-
39
-
-
0036668242
-
Links between innate and adaptive immunity via type I interferon
-
LeBon A, Tough DF. Links between innate and adaptive immunity via type I interferon. Curr Opin Immunol 2002; 14: 432-436.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 432-436
-
-
LeBon, A.1
Tough, D.F.2
-
40
-
-
0842301509
-
Type I interferon as a link between innate and adaptive immunity through dendritic cell stimulation
-
Tough DF. Type I interferon as a link between innate and adaptive immunity through dendritic cell stimulation. Leuk Lymphoma 2004; 45: 257-264.
-
(2004)
Leuk Lymphoma
, vol.45
, pp. 257-264
-
-
Tough, D.F.1
|