메뉴 건너뛰기




Volumn 21, Issue 18, 2007, Pages 2465-2472

Successful simplification of protease inhibitor-based HAART with triple nucleoside regimens in children vertically infected with HIV

Author keywords

CD8 T lymphocytes; HAART; HIV 1 infected children; Simplification; T cell V

Indexed keywords

ABACAVIR; ABACAVIR PLUS LAMIVUDINE PLUS ZIDOVUDINE; CD8 ANTIGEN; DIDANOSINE; INDINAVIR; LAMIVUDINE; LAMIVUDINE PLUS ZIDOVUDINE; LOPINAVIR; NELFINAVIR; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; T LYMPHOCYTE RECEPTOR BETA CHAIN; VIRUS RNA; ZIDOVUDINE;

EID: 36348957298     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAD.0b013e3282f1560b     Document Type: Article
Times cited : (16)

References (47)
  • 1
    • 0035936007 scopus 로고    scopus 로고
    • Effect of combination therapy including protease inhibitors on mortality among children and adolescents infected with HIV-1
    • Gortmaker SL, Hughes M, Cervia J, Bradi M, Johnson GM, Seage GR 3rd, et al. Effect of combination therapy including protease inhibitors on mortality among children and adolescents infected with HIV-1. N Engl J Med 2001; 345:1522-1528.
    • (2001) N Engl J Med , vol.345 , pp. 1522-1528
    • Gortmaker, S.L.1    Hughes, M.2    Cervia, J.3    Bradi, M.4    Johnson, G.M.5    Seage 3rd, G.R.6
  • 2
    • 0034641328 scopus 로고    scopus 로고
    • Reduction in mortality with availability of antiretroviral therapy for children with perinatal HIV-1 infection. Italian Register for HIV Infection in Children and the Italian National AIDS Registry
    • de Martino M, Tovo PA, Balducci M, Galli L, Gabbiano C, Rezza G, et al. Reduction in mortality with availability of antiretroviral therapy for children with perinatal HIV-1 infection. Italian Register for HIV Infection in Children and the Italian National AIDS Registry. JAMA 2000; 284:190-197.
    • (2000) JAMA , vol.284 , pp. 190-197
    • de Martino, M.1    Tovo, P.A.2    Balducci, M.3    Galli, L.4    Gabbiano, C.5    Rezza, G.6
  • 3
    • 9144272216 scopus 로고    scopus 로고
    • Adherence to antiretroviral therapy and its determinants in children with human immunodeficiency virus infection: A multicentre, national study
    • Giacomet V, Albano F, Starace F, de Franciscis A, Giaquinto C, Gattinara GC, et al. Adherence to antiretroviral therapy and its determinants in children with human immunodeficiency virus infection: a multicentre, national study. Acta Paediatr 2003; 92:1398-1402.
    • (2003) Acta Paediatr , vol.92 , pp. 1398-1402
    • Giacomet, V.1    Albano, F.2    Starace, F.3    de Franciscis, A.4    Giaquinto, C.5    Gattinara, G.C.6
  • 4
    • 0345256371 scopus 로고    scopus 로고
    • Patterns and correlates of discontinuation of the initial HAART regimen in an urban outpatient cohort
    • O'Brien ME, Clark RA, Besch CL, Myers L, Kissinger P. Patterns and correlates of discontinuation of the initial HAART regimen in an urban outpatient cohort. J Acquir Immune Defic Syndr 2003; 34:407-414.
    • (2003) J Acquir Immune Defic Syndr , vol.34 , pp. 407-414
    • O'Brien, M.E.1    Clark, R.A.2    Besch, C.L.3    Myers, L.4    Kissinger, P.5
  • 5
    • 0037231733 scopus 로고    scopus 로고
    • Adherence to prescribed antiretroviral therapy in human immunodeficiency virus-infected children in the PENTA 5 trial
    • Gibb DM, Goodall RL, Giacomet V, McGee L, Compagnucci A, Lyall H, et al. Adherence to prescribed antiretroviral therapy in human immunodeficiency virus-infected children in the PENTA 5 trial. Pediatr Infect Dis 2003; 22:56-62.
    • (2003) Pediatr Infect Dis , vol.22 , pp. 56-62
    • Gibb, D.M.1    Goodall, R.L.2    Giacomet, V.3    McGee, L.4    Compagnucci, A.5    Lyall, H.6
  • 6
    • 0344406674 scopus 로고    scopus 로고
    • Increased lipodystrophy is associated with increased exposure to highly active antiretroviral therapy in HIV-infected children
    • Vigano A, Mora S, Testolin C, Beccio S, Schneider L, Bricalli D, et al. Increased lipodystrophy is associated with increased exposure to highly active antiretroviral therapy in HIV-infected children. J Acquir Immune Defic Syndr 2003; 32:482-489.
    • (2003) J Acquir Immune Defic Syndr , vol.32 , pp. 482-489
    • Vigano, A.1    Mora, S.2    Testolin, C.3    Beccio, S.4    Schneider, L.5    Bricalli, D.6
  • 7
    • 16544380180 scopus 로고    scopus 로고
    • Natural history of lipid abnormalities and fat redistribution among human immunodeficiency virus-infected children receiving long-term, protease inhibitor-containing, highly active antiretroviral therapy regimens
    • Taylor P, Worrell C, Steinberg SM, Hazra R, Jankelevich S, Wood LV, et al. Natural history of lipid abnormalities and fat redistribution among human immunodeficiency virus-infected children receiving long-term, protease inhibitor-containing, highly active antiretroviral therapy regimens. Pediatrics 2004; 114:235-242.
    • (2004) Pediatrics , vol.114 , pp. 235-242
    • Taylor, P.1    Worrell, C.2    Steinberg, S.M.3    Hazra, R.4    Jankelevich, S.5    Wood, L.V.6
  • 8
    • 33646003839 scopus 로고    scopus 로고
    • Effects of highly active antiretroviral therapy on paediatric metabolite levels
    • Rhoads MP, Smith CJ, Tudor-Williams G. Effects of highly active antiretroviral therapy on paediatric metabolite levels. HIV Med 2006; 7:16-24.
    • (2006) HIV Med , vol.7 , pp. 16-24
    • Rhoads, M.P.1    Smith, C.J.2    Tudor-Williams, G.3
  • 9
    • 4444315072 scopus 로고    scopus 로고
    • Metabolic complications of HIV therapy in children
    • McComsey GA, Leonard E. Metabolic complications of HIV therapy in children. AIDS 2004; 18:1753-1768.
    • (2004) AIDS , vol.18 , pp. 1753-1768
    • McComsey, G.A.1    Leonard, E.2
  • 10
    • 33646811532 scopus 로고    scopus 로고
    • Dyslipidemia among perinatally HIV-infected children enrolled in the PACTS-HOPE cohort, 1999-2004: A longitudinal analysis
    • Carter RJ, Wiener J, Abrams EJ, Farley J, Nesheim S, Palumbo P, et al. Dyslipidemia among perinatally HIV-infected children enrolled in the PACTS-HOPE cohort, 1999-2004: a longitudinal analysis. J Acquir Immune Defic Syndr 2006; 41:453-460.
    • (2006) J Acquir Immune Defic Syndr , vol.41 , pp. 453-460
    • Carter, R.J.1    Wiener, J.2    Abrams, E.J.3    Farley, J.4    Nesheim, S.5    Palumbo, P.6
  • 11
    • 0036258816 scopus 로고    scopus 로고
    • Switch studies: A review
    • Murphy RL, Smith WJ. Switch studies: a review. HIV Med 2002; 3:146-155.
    • (2002) HIV Med , vol.3 , pp. 146-155
    • Murphy, R.L.1    Smith, W.J.2
  • 12
    • 0036822456 scopus 로고    scopus 로고
    • Simplification of antiretroviral treatment: How to sustain success, reduce toxicity and ensure adherence avoiding PI use
    • Barreiro P, Garcia-Benayas T, Soriano V, Gallant J. Simplification of antiretroviral treatment: how to sustain success, reduce toxicity and ensure adherence avoiding PI use. AIDS Rev 2002; 4:233-241.
    • (2002) AIDS Rev , vol.4 , pp. 233-241
    • Barreiro, P.1    Garcia-Benayas, T.2    Soriano, V.3    Gallant, J.4
  • 13
    • 33748042284 scopus 로고    scopus 로고
    • Benefits and concerns of simplification strategies in HIV-infected patients
    • Negredo E, Bonjoch A, Clotet B. Benefits and concerns of simplification strategies in HIV-infected patients. J Antimicrob Chemother 2006; 58:235-242.
    • (2006) J Antimicrob Chemother , vol.58 , pp. 235-242
    • Negredo, E.1    Bonjoch, A.2    Clotet, B.3
  • 14
    • 7744241696 scopus 로고    scopus 로고
    • Long-term efficacy after switching from protease inhibitor-containing highly active antiretroviral therapy to abacavir, lamivudine, and zidovudine
    • Opravil M, Baumann D, Chave JP, Furrer H, Calmy A, Bernasconi E, et al. Long-term efficacy after switching from protease inhibitor-containing highly active antiretroviral therapy to abacavir, lamivudine, and zidovudine. AIDS 2004; 18:2213-2215.
    • (2004) AIDS , vol.18 , pp. 2213-2215
    • Opravil, M.1    Baumann, D.2    Chave, J.P.3    Furrer, H.4    Calmy, A.5    Bernasconi, E.6
  • 15
    • 21544479407 scopus 로고    scopus 로고
    • Antiretroviral treatment simplification with 3 NRTIs or 2 NRTIs plus nevirapine in HIV-1-infected patients treated with successful first-line HAART
    • Bonjoch A, Paredes R, Galvez J, Miralles C, Videla S, Martinez E, et al. Antiretroviral treatment simplification with 3 NRTIs or 2 NRTIs plus nevirapine in HIV-1-infected patients treated with successful first-line HAART. J Acquir Immune Defic Synd 2005; 39:313-316.
    • (2005) J Acquir Immune Defic Synd , vol.39 , pp. 313-316
    • Bonjoch, A.1    Paredes, R.2    Galvez, J.3    Miralles, C.4    Videla, S.5    Martinez, E.6
  • 16
    • 21544442597 scopus 로고    scopus 로고
    • Induction with abacavir/lamivudine/zidovudine plus efavirenz for 48 weeks followed by 48-week maintenance with abacavir/lamivudine/zidovudine alone in antiretroviral-naive HIV-1-infected patients
    • Markowitz M, Hill-Zabala C, Lang J, DeJesus E, Liao Q, Lanier ER, et al. Induction with abacavir/lamivudine/zidovudine plus efavirenz for 48 weeks followed by 48-week maintenance with abacavir/lamivudine/zidovudine alone in antiretroviral-naive HIV-1-infected patients. J Acquir Immune Defic Syndr 2005; 39:257-264.
    • (2005) J Acquir Immune Defic Syndr , vol.39 , pp. 257-264
    • Markowitz, M.1    Hill-Zabala, C.2    Lang, J.3    DeJesus, E.4    Liao, Q.5    Lanier, E.R.6
  • 17
    • 4644346388 scopus 로고    scopus 로고
    • The rise and fall of triple nucleoside reverse transcriptase inhibitor (NRTI) regimens
    • Arribas JR. The rise and fall of triple nucleoside reverse transcriptase inhibitor (NRTI) regimens. J Antimicrob Chemother 2004; 54:587-592.
    • (2004) J Antimicrob Chemother , vol.54 , pp. 587-592
    • Arribas, J.R.1
  • 18
    • 4043162723 scopus 로고    scopus 로고
    • PENTA Steering Committee. PENTA guidelines for the use of antiretroviral therapy
    • Sharland M, Blanche S, Castelli G, Ramos J, Gibb DM. PENTA Steering Committee. PENTA guidelines for the use of antiretroviral therapy. HIV Med 2004; 5 (Suppl 2):61-86.
    • (2004) HIV Med , vol.5 , Issue.SUPPL. 2 , pp. 61-86
    • Sharland, M.1    Blanche, S.2    Castelli, G.3    Ramos, J.4    Gibb, D.M.5
  • 19
    • 0018841885 scopus 로고
    • Plasma cholesterol and triglyceride distributions in 13 665 children and adolescents: The Prevalence Study of the Lipid Research Clinics Program
    • Christensen B, Glueck C, Kwiterovich P, Degroot I, Chase G, Heiss G, et al. Plasma cholesterol and triglyceride distributions in 13 665 children and adolescents: the Prevalence Study of the Lipid Research Clinics Program. Pediatr Res 1980; 14:194-202.
    • (1980) Pediatr Res , vol.14 , pp. 194-202
    • Christensen, B.1    Glueck, C.2    Kwiterovich, P.3    Degroot, I.4    Chase, G.5    Heiss, G.6
  • 20
    • 0035834471 scopus 로고    scopus 로고
    • Kinetics of the T-cell receptor CD4 and CD8 V beta repertoire in HIV-1 vertically infected infants early treated with HAART
    • Romiti ML, Cancrini C, Castelli-Gattinara G, Di Cesare S, Ciaffi P, Bernardi S, et al. Kinetics of the T-cell receptor CD4 and CD8 V beta repertoire in HIV-1 vertically infected infants early treated with HAART. AIDS 2001; 15:2075-2084.
    • (2001) AIDS , vol.15 , pp. 2075-2084
    • Romiti, M.L.1    Cancrini, C.2    Castelli-Gattinara, G.3    Di Cesare, S.4    Ciaffi, P.5    Bernardi, S.6
  • 21
    • 0037000122 scopus 로고    scopus 로고
    • Computer-based design of an HLA haplotype and HIV-clade independent cytotoxic T-lymphocyte assay for monitoring HIV-specific immunity
    • Amicosante M, Gioia C, Montesano C, Casetti R, Topino S, D'Offizi G, et al. Computer-based design of an HLA haplotype and HIV-clade independent cytotoxic T-lymphocyte assay for monitoring HIV-specific immunity. Mol Med 2002; 8:798-807.
    • (2002) Mol Med , vol.8 , pp. 798-807
    • Amicosante, M.1    Gioia, C.2    Montesano, C.3    Casetti, R.4    Topino, S.5    D'Offizi, G.6
  • 22
    • 33748499796 scopus 로고    scopus 로고
    • Switching from PI-based-HAART to PI-sparing regimen is associated with improved specific HIV-immune responses in HIV-infected children
    • Pensieroso P, Romiti ML, Palma P, Castelli-Gattinare G, Bernardi S, Freda E, et al. Switching from PI-based-HAART to PI-sparing regimen is associated with improved specific HIV-immune responses in HIV-infected children. AIDS 2006; 20:1893-1896.
    • (2006) AIDS , vol.20 , pp. 1893-1896
    • Pensieroso, P.1    Romiti, M.L.2    Palma, P.3    Castelli-Gattinare, G.4    Bernardi, S.5    Freda, E.6
  • 23
    • 34249877189 scopus 로고    scopus 로고
    • Cellular HIV-1 DNA quantitation in patients during simplification therapy with protease inhibitor-sparing regimens
    • Sarmati L, Parisi SG, Nicastri E, d'Ettorre G, Andreoni C, Dori L, et al. Cellular HIV-1 DNA quantitation in patients during simplification therapy with protease inhibitor-sparing regimens. J Med Virol 2007; 79:880-886.
    • (2007) J Med Virol , vol.79 , pp. 880-886
    • Sarmati, L.1    Parisi, S.G.2    Nicastri, E.3    d'Ettorre, G.4    Andreoni, C.5    Dori, L.6
  • 24
    • 0242550686 scopus 로고    scopus 로고
    • Pediatric AIDS Clinical Trials Group. Lymphocyte subsets in healthy children from birth through 18 years of age: The Pediatric AIDS Clinical Trials Group P1009 study
    • Shearer WT, Rosenblatt HM, Gelman RS, Oyomopito R, Plaeger S, Stiehm ER, et al., Pediatric AIDS Clinical Trials Group. Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol 2003; 112:973-980.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 973-980
    • Shearer, W.T.1    Rosenblatt, H.M.2    Gelman, R.S.3    Oyomopito, R.4    Plaeger, S.5    Stiehm, E.R.6
  • 25
    • 3142582062 scopus 로고    scopus 로고
    • Triple nucleoside reverse transcriptase inhibitor therapy in children
    • Handforth J, Sharland M. Triple nucleoside reverse transcriptase inhibitor therapy in children. Paediatr Drugs 2004; 6:147-159.
    • (2004) Paediatr Drugs , vol.6 , pp. 147-159
    • Handforth, J.1    Sharland, M.2
  • 26
    • 0036720438 scopus 로고    scopus 로고
    • Persistence of wild-type virus and lack of temporal structure in the latent reservoir for human immunodeficiency virus type 1 in pediatric patients with extensive antiretroviral exposure
    • Ruff CT, Ray SC, Kwon P, Zinn R, Pendleton A, Hutton N, et al. Persistence of wild-type virus and lack of temporal structure in the latent reservoir for human immunodeficiency virus type 1 in pediatric patients with extensive antiretroviral exposure. J Virol 2002; 76:9481-9492.
    • (2002) J Virol , vol.76 , pp. 9481-9492
    • Ruff, C.T.1    Ray, S.C.2    Kwon, P.3    Zinn, R.4    Pendleton, A.5    Hutton, N.6
  • 27
    • 0037217708 scopus 로고    scopus 로고
    • Predictive value of provirus load and DNA human immunodeficiency virus genotype for successful abacavir-based simplified therapy
    • Pellegrin I, Caumont A, Garrigue I, Merel P, Schrive MH, Fleury H, et al. Predictive value of provirus load and DNA human immunodeficiency virus genotype for successful abacavir-based simplified therapy. J Infect Dis 2003; 187:38-46.
    • (2003) J Infect Dis , vol.187 , pp. 38-46
    • Pellegrin, I.1    Caumont, A.2    Garrigue, I.3    Merel, P.4    Schrive, M.H.5    Fleury, H.6
  • 28
    • 33745829765 scopus 로고    scopus 로고
    • Meaning of DNA detection during the follow-up of HIV-1 infected patients: A brief review
    • Re MC, Vitone F, Bon I, Schiavone P, Gibellini D. Meaning of DNA detection during the follow-up of HIV-1 infected patients: a brief review. New Microbiol 2006; 29:81-88.
    • (2006) New Microbiol , vol.29 , pp. 81-88
    • Re, M.C.1    Vitone, F.2    Bon, I.3    Schiavone, P.4    Gibellini, D.5
  • 29
    • 13144266673 scopus 로고    scopus 로고
    • An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses
    • Andre P, Groettrup M, Klenerman P, de Giuli R, Booth BL, Cerundolo V, et al. An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses. Proc Natl Acad Sci USA 1998; 95:13120-13124.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13120-13124
    • Andre, P.1    Groettrup, M.2    Klenerman, P.3    de Giuli, R.4    Booth, B.L.5    Cerundolo, V.6
  • 30
    • 20744437157 scopus 로고    scopus 로고
    • The HIV protease inhibitors nelfinavir and saquinavir, but not a variety of HIV reverse transcriptase inhibitors, adversely affect human proteasome function
    • Piccinini M, Rinaudo MT, Anselmino A, Buccinna B, Ramondetti C, Dematteis A, et al. The HIV protease inhibitors nelfinavir and saquinavir, but not a variety of HIV reverse transcriptase inhibitors, adversely affect human proteasome function. Antivir Ther 2005; 10:215-223.
    • (2005) Antivir Ther , vol.10 , pp. 215-223
    • Piccinini, M.1    Rinaudo, M.T.2    Anselmino, A.3    Buccinna, B.4    Ramondetti, C.5    Dematteis, A.6
  • 32
    • 27144433671 scopus 로고    scopus 로고
    • Partial treatment interruption of protease inhibitors augments HIV-specific immune responses in vertically infected pediatric patients
    • Legrand FA, Abadi J, Jordan KA, Davenport MP, Deeks SG, Fennelly GJ, et al. Partial treatment interruption of protease inhibitors augments HIV-specific immune responses in vertically infected pediatric patients. AIDS 2005; 19:1575-1585.
    • (2005) AIDS , vol.19 , pp. 1575-1585
    • Legrand, F.A.1    Abadi, J.2    Jordan, K.A.3    Davenport, M.P.4    Deeks, S.G.5    Fennelly, G.J.6
  • 33
    • 33845475641 scopus 로고    scopus 로고
    • Functional patterns of HIV-1-specific CD4T-cell responses in children are influenced by the extent of virus suppression and exposure
    • Correa R, Harari A, Vallelian F, Resino S, Munoz-Fernandez MA, Pantaleo G. Functional patterns of HIV-1-specific CD4T-cell responses in children are influenced by the extent of virus suppression and exposure. AIDS 2007; 21:23-30.
    • (2007) AIDS , vol.21 , pp. 23-30
    • Correa, R.1    Harari, A.2    Vallelian, F.3    Resino, S.4    Munoz-Fernandez, M.A.5    Pantaleo, G.6
  • 34
    • 0041381363 scopus 로고    scopus 로고
    • Similarities and differences in CD4+ and CD8+ effector and memory T cell generation
    • Seder RA, Ahmed R. Similarities and differences in CD4+ and CD8+ effector and memory T cell generation. Nat Immunol 2003; 4:835-842.
    • (2003) Nat Immunol , vol.4 , pp. 835-842
    • Seder, R.A.1    Ahmed, R.2
  • 35
    • 0035228238 scopus 로고    scopus 로고
    • A randomized, double-blind study of triple nucleoside therapy of abacavir, lamivudine, and zidovudine versus lamivudine and zidovudine in previously treated human immunodeficiency virus type 1-infected children. The CNAA3006 Study Team
    • Saez-Llorens X, Nelson RP Jr, Emmanuel P, Wiznia A, Mitchell C, Church JA, et al. A randomized, double-blind study of triple nucleoside therapy of abacavir, lamivudine, and zidovudine versus lamivudine and zidovudine in previously treated human immunodeficiency virus type 1-infected children. The CNAA3006 Study Team. Pediatrics 2001; 107:E4.
    • (2001) Pediatrics , vol.107
    • Saez-Llorens, X.1    Nelson Jr, R.P.2    Emmanuel, P.3    Wiznia, A.4    Mitchell, C.5    Church, J.A.6
  • 36
    • 0037006656 scopus 로고    scopus 로고
    • Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: The PENTA 5 randomised trial
    • Paediatric European Network for Treatment of AIDS PENTA
    • Paediatric European Network for Treatment of AIDS (PENTA). Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: the PENTA 5 randomised trial. Lancet 2002; 359:733-740.
    • (2002) Lancet , vol.359 , pp. 733-740
  • 37
    • 0037231547 scopus 로고    scopus 로고
    • Metabolic complications of antiretroviral therapy in children
    • Leonard EG, McComsey GA. Metabolic complications of antiretroviral therapy in children. Pediatr Infect Dis J 2003; 22:77-84.
    • (2003) Pediatr Infect Dis J , vol.22 , pp. 77-84
    • Leonard, E.G.1    McComsey, G.A.2
  • 38
    • 0038324257 scopus 로고    scopus 로고
    • TRIZAL study: Switching from successful HAART to Trizivir (abacavir-lamivudine-zidovudine combination tablet): 48 weeks efficacy, safety and adherence results
    • Katlama C, Fenske S, Gazzard B, Lazzarin A, Clumeck N, Mallolas J, et al. TRIZAL study: switching from successful HAART to Trizivir (abacavir-lamivudine-zidovudine combination tablet): 48 weeks efficacy, safety and adherence results. HIV Med 2003; 4:79-86.
    • (2003) HIV Med , vol.4 , pp. 79-86
    • Katlama, C.1    Fenske, S.2    Gazzard, B.3    Lazzarin, A.4    Clumeck, N.5    Mallolas, J.6
  • 39
    • 21844443541 scopus 로고    scopus 로고
    • Substituting abacavir for hyperlipidemiaassociated protease inhibitors in HAART regimens improves fasting lipid profiles, maintains virologic suppression, and simplifies treatment
    • Keiser PH, Sension MG, DeJesus E, Rodriguez A, Olliffe JF, Williams VC, et al. Substituting abacavir for hyperlipidemiaassociated protease inhibitors in HAART regimens improves fasting lipid profiles, maintains virologic suppression, and simplifies treatment. BMC Infect Dis 2005; 5:2.
    • (2005) BMC Infect Dis , vol.5 , pp. 2
    • Keiser, P.H.1    Sension, M.G.2    DeJesus, E.3    Rodriguez, A.4    Olliffe, J.F.5    Williams, V.C.6
  • 40
    • 0038121117 scopus 로고    scopus 로고
    • First Pediatric Switch Study. Impact of protease inhibitor substitution with efavirenz in HIV-infected children: Results of the First Pediatric Switch Study
    • Mc Comsey G, Bhumbra N, Ma JF, Rathore M, Alvarez A, First Pediatric Switch Study. Impact of protease inhibitor substitution with efavirenz in HIV-infected children: results of the First Pediatric Switch Study. Pediatrics 2003; 111:275-281.
    • (2003) Pediatrics , vol.111 , pp. 275-281
    • Mc Comsey, G.1    Bhumbra, N.2    Ma, J.F.3    Rathore, M.4    Alvarez, A.5
  • 41
    • 30444446823 scopus 로고    scopus 로고
    • Improvement in dyslipidaemia after switching stavudine to tenofovir and replacing protease inhibitors with efavirenz in HIV-infected children
    • Vigano A, Aldrovandi GM, Giacomet V, Merlo M, Martelli L, Beretta S, et al. Improvement in dyslipidaemia after switching stavudine to tenofovir and replacing protease inhibitors with efavirenz in HIV-infected children. Antivir Ther 2005; 10:917-924.
    • (2005) Antivir Ther , vol.10 , pp. 917-924
    • Vigano, A.1    Aldrovandi, G.M.2    Giacomet, V.3    Merlo, M.4    Martelli, L.5    Beretta, S.6
  • 42
    • 0035842484 scopus 로고    scopus 로고
    • Total cholesterol/HDL cholesterol ratio vs LDL cholesterol/HDL cholesterol ratio as indices of ischemic heart disease risk in men: The Quebec Cardiovascular Study
    • Lemieux I, Lamarche B, Couillard C, Pascot A, Cantin B, Bergeron J, et al. Total cholesterol/HDL cholesterol ratio vs LDL cholesterol/HDL cholesterol ratio as indices of ischemic heart disease risk in men: the Quebec Cardiovascular Study. Arch Intern Med 2001; 161:2685-2692.
    • (2001) Arch Intern Med , vol.161 , pp. 2685-2692
    • Lemieux, I.1    Lamarche, B.2    Couillard, C.3    Pascot, A.4    Cantin, B.5    Bergeron, J.6
  • 43
    • 0035902493 scopus 로고    scopus 로고
    • Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction
    • Stein JH, Klein MA, Bellehumeur JL, McBride PE, Wiebe DA, Otvos JD, et al. Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction. Circulation 2001; 104:257-262.
    • (2001) Circulation , vol.104 , pp. 257-262
    • Stein, J.H.1    Klein, M.A.2    Bellehumeur, J.L.3    McBride, P.E.4    Wiebe, D.A.5    Otvos, J.D.6
  • 44
    • 3142707107 scopus 로고    scopus 로고
    • Antiretroviral therapy, fat redistribution and hyperlipidemia in HIV-infected children in Europe
    • European Paediatric Lipodystrophy Group
    • European Paediatric Lipodystrophy Group. Antiretroviral therapy, fat redistribution and hyperlipidemia in HIV-infected children in Europe. AIDS 2004; 18:1443-1451.
    • (2004) AIDS , vol.18 , pp. 1443-1451
  • 45
    • 15044343044 scopus 로고    scopus 로고
    • Prevalence of elevated cholesterol and associated risk factors among perinatally HIV-infected children (4-19 years) in PACTG 219C
    • Farley J, Gona P, Crain M, Cervia J, Oleske J, Seage G, et al. Prevalence of elevated cholesterol and associated risk factors among perinatally HIV-infected children (4-19 years) in PACTG 219C. J Acquir Immune Defic Syndr 2005; 38:480-487.
    • (2005) J Acquir Immune Defic Syndr , vol.38 , pp. 480-487
    • Farley, J.1    Gona, P.2    Crain, M.3    Cervia, J.4    Oleske, J.5    Seage, G.6
  • 46
    • 24044455416 scopus 로고    scopus 로고
    • Nucleoside analogues toxicities related to mitochondrial dysfunction: Focus on HIV-infected children
    • Vigano A, Giacomet V. Nucleoside analogues toxicities related to mitochondrial dysfunction: focus on HIV-infected children. Antivir Ther 2005; 10 (Suppl 2):M53-M64.
    • (2005) Antivir Ther , vol.10 , Issue.SUPPL. 2
    • Vigano, A.1    Giacomet, V.2
  • 47
    • 0346333250 scopus 로고    scopus 로고
    • Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level
    • Nolan D, Hammond E, James I, McKinnon E, Mallal S. Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level. Antivir Ther 2003; 8:617-626.
    • (2003) Antivir Ther , vol.8 , pp. 617-626
    • Nolan, D.1    Hammond, E.2    James, I.3    McKinnon, E.4    Mallal, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.