High rate of discordance between clinical and autopsy diagnoses in blood and marrow transplantation

Bone Marrow Transplantation

Volumn 40, Issue 11, 2007, Pages 1049-1053

  Seftel, M D ^a,b,c   Ho, M ^a,d   Pruthi, D ^a,d   Orbanski, S ^b   Rubinger, M ^a,b,c   Schacter, B ^a,b,c   Szwajcer, D ^a,b,c   Bredeson, C ^e   Demers, A A ^d  

^a UNIVERSITY OF MANITOBA   (Canada)

^b Manitoba Blood and Marrow Transplant Program   (Canada)

^c HEALTH SCIENCES CENTRE   (Canada)

^d Epidemiology and Cancer Registry   (Canada)

^e MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALLOGRAFT; ARTICLE; AUTOPSY; BONE MARROW TRANSPLANTATION; CAUSE OF DEATH; CLINICAL ARTICLE; COMORBIDITY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; HEALTH SERVICES RESEARCH; HUMAN; HUMAN TISSUE; INTENSIVE CARE UNIT; MALE; MEDICAL DECISION MAKING; MORTALITY; MYELOABLATIVE CONDITIONING; PREDICTION; PRIORITY JOURNAL; REDUCED INTENSITY CONDITIONING; STEM CELL TRANSPLANTATION; TEACHING HOSPITAL; TREATMENT INDICATION; TREND STUDY;

ADOLESCENT; ADULT; AGED; AUTOPSY; BONE MARROW TRANSPLANTATION; CANADA; CAUSE OF DEATH; COMORBIDITY; DIAGNOSTIC ERRORS; FEMALE; HUMANS; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES;

EID: 36348947410     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/sj.bmt.1705855     Document Type: Article

References (32)

1. Lowry F. Failure to perform autopsies means some MDs 'walking in a fog of misplaced optimism'. CMAJ 1995; 153: 811-814.
2. Sinard JH. Factors affecting autopsy rates, autopsy request rates, and autopsy findings at a large academic medical center. Exp Mol Pathol 2001; 70: 333-343.
3. Allan DS, Belanger R, Busque L, Cohen S, Fish D, Roy DC et al. Maintaining high autopsy rates in a Canadian blood and marrow transplant program: Preserving a diagnostic and research tool. Bone Marrow Transplant 2005; 35: 781-785.
4. Shojania KG, Burton EC, McDonald KM, Goldman L. Changes in rates of autopsy-detected diagnostic errors over time: A systematic review. JAMA 2003; 289: 2849-2856.
5. Spiliopoulou C, Papadodima S, Kotakidis N, Koutselinis A. Clinical diagnoses and autopsy findings: A retrospective analysis of 252 cases in Greece. Arch Pathol Lab Med 2005; 129: 210-214.
6. Avgerinos DV, Bjornsson J. Malignant neoplasms: Discordance between clinical diagnoses and autopsy findings in 3,118 cases. APMIS 2001; 109: 774-780.
7. Burton EC, Troxclair DA, Newman III WP. Autopsy diagnoses of malignant neoplasms: How often are clinical diagnoses incorrect? JAMA 1998; 280: 1245-1248.
8. Xavier AC, Siqueira SA, Costa LJ, Mauad T, Nascimento Saldiva PH. Missed diagnosis in hematological patients - an autopsy study. Virchows Arch 2005; 446: 225-231.
9. Nichols L, Aronica P, Babe C. Are autopsies obsolete? Am J Clin Pathol 1998; 110: 210-218.
10. Burton JL, Wells M. The alder hey affair. Arch Dis Child 2002; 86: 4-7.
11. Veress B, Alafuzoff I. A retrospective analysis of clinical diagnoses and autopsy findings in 3042 cases during two different time periods. Hum Pathol 1994; 25: 140-145.
12. Hofmeister CC, Marinier DE, Czerlanis C, Stiff PJ. Clinical utility of autopsy after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2007; 13: 26-30.
13. Sonderegger-Iseli K, Burger S, Muntwyler J, Salomon F. Diagnostic errors in three medical eras: A necropsy study. Lancet 2000; 355: 2027-2031.
14. Scottolini AG, Weinstein SR. The autopsy in clinical quality control. JAMA 1983; 250: 1192-1194.
15. Britton M. Clinical diagnostics: Experience from 383 autopsied cases. Acta Med Scand 1974; 196: 211-219.
16. Aalten CM, Samson MM, Jansen PA. Diagnostic errors; the need to have autopsies. Neth J Med 2006; 64: 186-190.
17. Combes A, Mokhtari M, Couvelard A, Trouillet JL, Baudot J, Henin D et al. Clinical and autopsy diagnoses in the intensive care unit: A prospective study. Arch Intern Med 2004; 164: 389-392.
18. Ferguson RP, Burkhardt L, Hennawi G, Puthumana L. Consecutive autopsies on an internal medicine service. South Med J 2004; 97: 335-337.
19. Goldman L, Sayson R, Robbins S, Cohn LH, Bettmann M, Weisberg M. The value of the autopsy in three medical eras. N Engl J Med 1983; 308: 1000-1005.
20. Peacock SJ, Machin D, Duboulay CE, Kirkham N. The autopsy: A useful tool or an old relic? J Pathol 1988; 156: 9-14.
21. The Royal College of Pathologists of Australasia Autopsy Working Party. The decline of the hospital autopsy: A safety and quality issue for healthcare in Australia. Med J Aust 2004; 180: 281-285.
22. Dimopoulos G, Piagnerelli M, Berre J, Salmon I, Vincent JL. Post mortem examination in the intensive care unit: Still useful? Intensive Care Med 2004; 30: 2080-2085.
23. Juric G, Tentor D, Jakic-Razumovic J. Autopsy findings and clinical diagnoses: Retrospective study of 3,117 autopsies. Croat Med J 1999; 40: 71-76.
24. Baddley JW, Stroud TP, Salzman D, Pappas PG. Invasive mold infections in allogeneic bone marrow transplant recipients. Clin Infect Dis 2001; 32: 1319-1324.
25. Grow WB, Moreb JS, Roque D, Manion K, Leather H, Reddy V et al. Late onset of invasive Aspergillus infection in bone marrow transplant patients at a university hospital. Bone Marrow Transplant 2002; 29: 15-19.
26. Ninin E, Milpied N, Moreau P, Andre-Richet B, Morineau N, Mahe B et al. Longitudinal study of bacterial, viral, and fungal infections in adult recipients of bone marrow transplants. Clin Infect Dis 2001; 33: 41-47.
27. Osarogiagbon RU, Defor TE, Weisdorf MA, Erice A, Weisdorf DJ. CMV antigenemia following bone marrow transplantation: Risk factors and outcomes. Biol Blood Marrow Transplant 2000; 6: 280-288.
28. Yoo JH, Lee DG, Choi SM, Choi JH, Park YH, Kim YJ et al. Infectious complications and outcomes after allogeneic hematopoietic stem cell transplantation in Korea. Bone Marrow Transplant 2004; 34: 497-504.
29. Maertens J, Verhaegen J, Demuynck H, Brock P, Verhoef G, Vandenberghe P et al. Autopsy-controlled prospective evaluation of serial screening for circulating galactomannan by a sandwich enzyme-linked immunosorbent assay for hematological patients at risk for invasive Aspergillosis. J Clin Microbiol 1999; 37: 3223-3228.
30. Herbrecht R, Letscher-Bru V, Oprea C, Lioure B, Waller J, Campos F et al. Aspergillus galactomannan detection in the diagnosis of invasive aspergillosis in cancer patients. J Clin Oncol 2002; 20: 1898-1906.
31. Maertens J, Verhaegen J, Lagrou K, Van EJ, Boogaerts M. Screening for circulating galactomannan as a noninvasive diagnostic tool for invasive aspergillosis in prolonged neutropenic patients and stem cell transplantation recipients: A prospective validation. Blood 2001; 97: 1604-1610.
32. Boeckh M, Gooley TA, Myerson D, Cunningham T, Schoch G, Bowden RA. Cytomegalovirus pp65 antigenemia-guided early treatment with ganciclovir versus ganciclovir at engraftment after allogeneic marrow transplantation: A randomized double-blind study. Blood 1996; 88: 4063-4071.