A recombinant herpes simplex virus type 1 expressing two additional copies of gK is more pathogenic than wild-type virus in two different strains of mice

Journal of Virology

Volumn 81, Issue 23, 2007, Pages 12962-12972

  Mott, Kevin R ^a   Perng, Guey Chuen ^b   Osorio, Yanira ^a   Kousoulas, Konstantin G ^c   Ghiasi, Homayon ^a  

^a BURNS AND ALLEN RESEARCH INSTITUTE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; GLYCOPROTEIN K; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEPHARITIS; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CORNEA; EYE DISEASE; FEMALE; GENE EXPRESSION; GK GENE; HERPES SIMPLEX VIRUS 1; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; SCAR FORMATION; TRIGEMINUS GANGLION; VIRUS GENE; VIRUS INFECTION; VIRUS LATENCY; VIRUS MUTANT; VIRUS RECOMBINANT; VIRUS VIRULENCE; WILD TYPE;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CORNEA; GENE DELETION; GENE DOSAGE; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 1, HUMAN; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; TRIGEMINAL GANGLION; VIRAL PROTEINS; VIRULENCE FACTORS;

HUMAN HERPESVIRUS 1; MUS; SIMPLEXVIRUS;

EID: 36348929456     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01442-07     Document Type: Article

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