HIV vaccine trials: Reconsidering the therapeutic misconception and the question of what constitutes trial related injuries

Developing World Bioethics

Volumn 7, Issue 3, 2007, Pages

  Schüklenk, Udo ^a   Ashcroft, Richard ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; UNCLASSIFIED DRUG; VAXGEN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; CLINICAL TRIAL; DRUG EFFICACY; EDITORIAL; HIGH RISK BEHAVIOR; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION PREVENTION; PRIORITY JOURNAL; RESEARCH ETHICS; RESEARCH SUBJECT; SEROCONVERSION; SEXUALLY TRANSMITTED DISEASE;

EID: 36249031819     PISSN: 14718731     EISSN: None     Source Type: Journal    
DOI: 10.1111/dewb_210.x     Document Type: Editorial

References (14)

1. D. Tarantola et al. Ethical Considerations Related to the Provision of Care and Treatment in Vaccine Trials. Vaccine 2007 25 : 4863 4874.
2. C. Weijer G.J. LeBlanc. The Balm of Gilead: Is the Provision of Treatment to Those who Seroconvert in HIV Prevention Trials a Matter of Moral Obligation or Moral Negotiation? J Law Med Ethics 2006 36 : 793 808.
3. U. Schüklenk R. Ashcroft. International Research Ethics. Bioethics 2000 14 : 158 172.
4. C. Slack et al. Provision of HIV Treatment in HIV Preventive Vaccine Trials: A Developing Country Perspective. Soc Sci Med 2005 60 : 1197 1208.
5. Weijer & LeBlanc, op. cit. note 2, p. 798.
6. Slack et al., op. cit. note 3, p. 1199.
7. Ibid: 1199.
8. Ibid: 1199.
9. E.J. Robinson et al. Lay Public's Understanding of Equipoise and Randomisation in Randomised Controlled Trials. Health Technol Assess 2005 9 (8 1 192
10. J. Flory E. Emanuel. Interventions to Improve Research Participants' Understanding in Informed Consent for Research: S Systematic Review. JAMA 2004 292 : 1593 1601.
11. Weijer & LeBlanc, op. cit. note 2, p. 798.
12. U. Schüklenk. The Standard of Care Debate: Against the Myth of an International Consensus Opinion. J Med Ethics 2004 30 : 194 197.
13. T. Tucker C. Slack. Not If but How? Caring for HIV-1 Vaccine Trial Participants in South Africa. Lancet 2003 362 : 995.
14. E. Lirri. 2007. Doctors Speak Out on Failed AIDS Trials. Daily Monitor (Uganda), 18 August: Online. Available at: http://www.monitor.co.ug/news/ news08181.php [Accessed 22 Aug 2007].