Lipid analysis of normal dermis and hypertrophic scars

Wound Repair and Regeneration

Volumn 15, Issue 6, 2007, Pages 833-837

  Nomura, Tadashi ^a,b   Terashi, Hiroto ^b   Omori, Makoto ^b   Sakurai, Atsushi ^b   Sunagawa, Takeru ^b   Hasegawa, Masumi ^b   Tahara, Shinya ^b  

^a NATIONAL HOSPITAL ORGANIZATION HIMEJI MEDICAL CENTER   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; FATTY ACID; LIPID;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DERMIS; FIBROBLAST; HUMAN; HUMAN CELL; HYPERTROPHIC SCAR; IN VITRO STUDY; IN VIVO STUDY; LIPID ANALYSIS; PRIORITY JOURNAL;

ARACHIDONIC ACID; CICATRIX, HYPERTROPHIC; DERMIS; FATTY ACIDS; FIBROBLASTS; HUMANS; PHOSPHOLIPIDS;

EID: 36249029139     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2007.00289.x     Document Type: Article

References (21)

1. Terashi H, Izumi K, Rhodes LM, Marcelo CL. Human stratified squamous epithelia differ in cellular fatty acid composition. J Dematol Sci 2000 24 : 4 13.
2. Marcelo CL, Dunham WR. The effect of fatty acid composition and retinoic acid on human keratinocyte plasma membrane viscosity. In : Shuröder J-M, editor. Fatty acids and inflammatory skin diseases. Basel : Birkhäuser, 1999 : 159 74.
3. Graber R, Sumida C, Nunaz A. Fatty acids and cell signal transduction. J Lipid Med Cell Signal 1994 9 : 91 116.
4. Tredget EE, Nedelec B, Scott PG, Ghahary A. Hypertrophic scars, keloids, and contractures. The cellular and molecular basis for therapy. Surg Clin North Am 1997 77 : 701 30.
5. Kischer CW, Bialy JF. The mast cell in hypertrophic scars. Tex Rep Bio Med 1972 32 : 327 38.
6. Younai A, Nichter LS, Wellisz T, Reinisch J, Nimni ME, Tuan TL. Modulation of collagen synthesis by transforming growth factor-β in keloid and hypertrophic scar fibroblasts. Ann Plast Surg 1994 33 : 148 54.
7. Low L. Keloids in rural black South Africans. Part 3: a lipid model for the prevention and treatment of keloid formations. Prostaglandin Leukot Essent Fatty Acids 2000 63 : 255 62.
8. Shakespeare PG, Strange R. Linoleic acid in hypertrophic scars. Burns 1981 9 : 7 12.
9. Balazs L, Okolicany J, Ferrebee M, Tolley B, Tigyi G. Topical application of the phospholipids growth factor lysophosphatidic acid promotes wound healing in vivo. Am J Physiol Regulatory Integr Comp Physiol 2001 280 : R466 72.
10. Tachi M. Human epidermal lipids during meddle fetal period. St. Luke's J Health Sci 1998 6 : 1 9.
11. Cardoso CRB, Souza MA, Ferro EAV, Favoreto S, Pena JDO. Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wound. Wound Rep Reg 2004 12 : 235 43.
12. Marcelo CL, Dunham WR. Fatty acid metabolism studies of human epithelial cell cultures. J Lipid Res 1993 34 : 2077 90.
13. Ziboh VA, Chapkin RS. Metabolism and function of skin lipids. Prog Lipid Res 1988 27 : 81 105.
14. Marcelo CL, Voorhees JJ. Cyclic nucleotides and arachidonate metabolites is psoriasis. In : Ward PA, editor. Handbook of inflammation: immunology of inflammation. Amsterdam : Elsevier, 1983 : 189 209.
15. Ziboh VA. Biosynthesis of prostaglandin E2 in human skin: subcellular localization and inhibition by unsaturated fatty acids and anti-inflammatory drugs. J Lipid Res 1973 14 : 377 84.
16. Scott PG, Ghahary A. Biological basis of hypertrophic scarring. Adv Struct Biol 1994 3 : 157 202.
17. Hayashi T, Nishihira J, Koyama Y, Sasaki S, Yamamoto Y. Decreased prostaglandin E2 production by inflammatory cytokine and lower expression of EP2 receptor result in increased collagen synthesis in keloid fibroblasts. J Invest Dermatol 2006 126 : 990 7.
18. Ignotz RA, Massague J. Transforming growth factor β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 1986 261 : 4337 45.
19. 1 on cultured dermal fibroblasts from normal and hypertrophic scarred skin. J Dematol Sci 1997 14 : 217 24.
20. 2. Burns 2006 32 : 299 304.
21. Kössi J, Pelton J, Uotila P, Latto M. Differential effects of hexoses and sucrose, and platelet-derived growth factor isoforms on cyclooxygenase-1 and -2 mRNA expression in keloid, hypertrophic scar and granulation tissue fibroblasts. Arch Dermatol Res 2001 293 : 126 32.