Fluorescence spectroscopic and 19F NMR Studies of Human Thymidylate Synthase with its Cognate RNA

Journal of Biomolecular Structure and Dynamics

Volumn 25, Issue 3, 2007, Pages 253-269

  Hasnat, Abul ^a   Bichenkova, Elena ^a   Yu, Xuan ^a   Arnold, J R P ^b   Fisher, Julie ^b   Fedorova, Olga ^c   Andrews, Julie ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

Author keywords

19F NMR; FdUMP; Fluorescence spectroscopy; Human thymidylate synthase; Methotrexate; RNA binding

Indexed keywords

DEOXYURIDINE PHOSPHATE; FLUORINE; FOLIC ACID; FOLINIC ACID; MESSENGER RNA; METHOTREXATE; RECOMBINANT PROTEIN; RNA; THYMIDYLATE SYNTHASE;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; ENZYME ACTIVITY; FLUORESCENCE SPECTROSCOPY; HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA BINDING; SPECTROMETER; STOICHIOMETRY;

EID: 36248978239     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2007.10507174     Document Type: Article

References (34)

1. Rustum, Y. M., 2004. Front Biosci, 9:2467–2473.
2. McGuire, J. J., 2003. Curr Pharm Des, 9:2593–2613.
3. Chu, E., Callender, M. A., Farrell, M. P., and Schmitz, J. C., 2003. Cancer Chemother Pharmacol, 52:S80–89. Suppl 1
4. Douglas, K. T., 1987. Med Res Rev, 7:441–475.
5. Chu, E., Koeller, D. M., Casey, J. L., Drake, J. C., Chabner, B. A., Elwood, P. C., Zinn, S., and Allegra, C. J., 1991. Proc Natl Acad Sci USA, 88:8977–8981.
6. Chu, E., Voeller, D., Koeller, D. M., Drake, J. C., Takimoto, C. H., Maley, G. F., Maley, F., and Allegra, C. J., 1993. Proc Natl Acad Sci USA, 90:517–521.
7. Chu, E., Voeller, D. M., Jones, K. L., Takechi, T., Maley, G. F., Maley, F., Segal, S., and Allegra, C. J., 1994. Mol Cell Biol, 14:207–213.
8. Voeller, D. M., Zajac-Kaye, M., Fisher, R. J., and Allegra, C. J., 2002. Biochem Biophys Res Commun, 297:24–31.
9. Chu, E., Cogliati, T., Copur, S. M., Borre, A., Voeller, D. M., Allegra, C. J., and Segal, S., 1996. Nucleic Acids Res, 24:3222–3228.
10. Lin, X., Mizunuma, N., Chen, T., Copur, S. M., Maley, G. F., Liu, J., Maley, F., and Chu, E., 2000. Nucleic Acids Res, 28:4266–4274.
11. Chu, E., and Allegra, C. J., 1996. Bioessays, 18:191–198.
12. Chu, E., and Allegra, C. J., 1996. Adv Enzyme Regul, 36:143–163.
13. Carpenter, M. L., Oliver, A. W., and Kneale, G. G., 2001. Methods Mol Biol, 148:491–502.
14. Cho, J., and Rando, R. R., 2000. Nucleic Acids Res, 28:2158–2163.
15. Lewis, C. A., Jr, Ellis, P. D., and Dunlap, R. B., 1978. Biochem Biophys Res Commun, 83:1509–1517.
16. Lewis, C. A., Jr, Ellis, P. D., and Dunlap, R. B., 1980. Biochemistry, 19:116–123.
17. Lewis, C. A., Jr, Ellis, P. D., and Dunlap, R. B., 1981. Biochemistry, 20:2275–2285.
18. Zhang, H. C., Cisneros, R. J., Deng, W. L., Zapf, J. W., Johnson, L. F., and Dunlap, R. B., 1991. Biochim Biophys Acta, 1077:35–46.
19. Pedersen-Lane, J., Maley, G. F., Chu, E., and Maley, F., 1997. Protein Expr Purif, 10:256–262.
20. Wahba, A. J., and Friedkin, M., 1962. J Biol Chem, 237:3794–3801.
21. Bakhtiar, R., and Nelson, R. W., 2000. Biochem Pharmacol, 59:891–905.
22. Murray, J. B., Collier, A. K., and Arnold, J. R., 1994. Anal Biochem, 218:177–184.
23. Bichenkova, E. V., Frau, S., Fedorova, O. S., and Douglas, K. T., 2001. Nucleosides Nucleotides Nucleic Acids, 20:157–168.
24. Fedorova, O. S., Nevinsky, G. A., Koval, V. V., Ishchenko, A. A., Vasilenko, N. L., and Douglas, K. T., 2002. Biochemistry, 41:1520–1528.
25. Marks, A. H., Bhadra, P. K., McDowell, D. G., French, D. J., Douglas, K. T., Bichenkova, E. V., and Bryce, R. A., 2005. J Biomol Struct Dyn, 23:49–62.
26. Reilly, R. T., Barbour, K. W., Dunlap, R. B., and Berger, F. G., 1995. Mol Pharmacol, 48:72–79.
27. Reilly, R. T., Forsthoefel, A. M., and Berger, F. G., 1997. Arch Biochem Biophys, 342:338–343.
28. Galivan, J. H., Maley, G. F., and Maley, F., 1976. Biochemistry, 15:356–362.
29. Dev, I. K., Dallas, W. S., Ferone, R., Hanlon, M., McKee, D. D., and Yates, B. B., 1994. J Biol Chem, 269:1873–1882.
30. Allen, M., Varani, L., and Varani, G., 2001. Methods Enzymol, 339:357–376.
31. Byrd, R. A., Dawson, W. H., Ellis, P. D., and Dunlap, R. B., 1977. J Am Chem Soc, 99:6139–6141.
32. Connick, T. J., Reilly, R. T., Dunlap, R. B., and Ellis, P. D., 1993. Biochemistry, 32:9888–9895.
33. Ghisolfi-Nieto, L., Joseph, G., Puvion-Dutilleul, F., Amalric, F., and Bouvet, P., 1996. J Mol Biol, 260:34–53.
34. Phan, J., Koli, S., Minor, W., Dunlap, R. B., Berger, S. H., and Lebioda, L., 2001. Biochemistry, 40:1897–1902.