The complexities of air pollution regulation: The need for an integrated research and regulatory perspective

Toxicological Sciences

Volumn 100, Issue 2, 2007, Pages 318-327

  Nadadur, Srikanth S ^a,g   Miller, C Andrew ^b   Hopke, Philip K ^c   Gordon, Terry ^d   Vedal, Sverre ^e   Vandenberg, John J ^a   Costa, Daniel I ^f  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c CLARKSON UNIVERSITY   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

^f U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^g NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Air pollution; Criteria pollutants; Epidemiology; Monitoring; PM; Regulation; Toxicity

Indexed keywords

CARBON MONOXIDE; LEAD; NITROGEN OXIDE; SULFUR DIOXIDE; VOLATILE ORGANIC COMPOUND;

AIR ANALYSIS; AIR POLLUTANT; AIR POLLUTION; AIR POLLUTION CONTROL; AIR QUALITY; ENVIRONMENTAL MANAGEMENT; HEALTH HAZARD; HUMAN; NONHUMAN; PARTICULATE MATTER; POLLUTION MONITORING; RESEARCH; REVIEW; RISK ASSESSMENT;

AIR POLLUTANTS; AIR POLLUTION; ANIMALS; BIOMEDICAL RESEARCH; GOVERNMENT REGULATION; HUMANS; OZONE; PARTICLE SIZE; PARTICULATE MATTER; UNITED STATES; UNITED STATES ENVIRONMENTAL PROTECTION AGENCY;

ANIMALIA;

EID: 36248967649     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm170     Document Type: Review

References (24)

1. Anderson, H. R., Atkinson, R. W., Peacock, J. L., Sweeting, M. J., and Marston, L. (2005). Ambient particulate matter and health effects: Publication bias in studies of short-term associations. Epidemiology 16, 155-163.
2. Bell, M. L., Dominici, F., and Samet, J. M. (2005). A meta-analysis of time-series studies of ozone and mortality with comparison to the national morbidity, mortality, and air pollution study. Epidemiology 16, 436-445.
3. Brauer, M., Brumm, J., Vedal, S., and Petkau, A. J. (2002). Exposure misclassification and threshold concentrations in time series analysis of air pollution health effects. Risk Anal. 22, 1183-1193.
4. Cheng, Y. S., Yeh, H. C., Mauderly, J. L., and Mokler, B. V. (1984). Characterization of diesel exhaust in a chronic inhalation study. Am. Ind. Hyg. Assoc. J. 45, 547-555.
5. Fraser, M. P., Yue, Z. W., Tropp, R. J., Kohl, S. D., and Chow, J. C. (2002). Molecular composition of organic fine particulate matter in Houston, TX. Atmos. Environ. 36, 5751-5758.
6. Gilmour, M. I., O'Connor, S., Dick, C. A. J., Miller, C. A., and Linak, W. P. (2004). Differential pulmonary inflammation and in vitro cytotoxicity of size-fractionated fly ash particles from pulverized coal combustion. J. Air Waste Manage. Assoc. 54, 286-295.
7. Harkema, J. R., Keeler, G., Wagner, J., Morishita, M., Timm, E., Hotchkiss, J., Marsik, F., Dvonch, T., Kaminski, N., and Barr, E. (2004). Effects of concentrated ambient particles on normal and hypersecretory airways in rats. Res. Rep. Health Eff. Inst: 120 1- 68; discussion, 69-79.
8. Hopke, P. K. (1985). Receptor Modeling in Environmental Chemistry. Wiley/Interscience, New York, NY.
9. Hwang, J. S., Nadziejko, C., and Chen, L. C. (2005). Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice. III. Acute and chronic effects of CAPs on heart rate, heart-rate fluctuation, and body temperature. Inhal. Toxicol. 17, 199-207.
10. Linak, W. P., Miller, C. A., Seames, W. S., Wendt, J. O. L., Ishinomori, T., Endo, Y., and Miyamae, S. (2002). On trimodal particle size distributions in fly ash from pulverized coal combustion. Proc. Combust. Inst. 29, 441-447.
11. McDonald, J. D., Eide, I., Seagrave, J., Zielinska, B., Whitney, K., Lawson, D. R., and Mauderly, J. L. (2004). Relationship between composition and toxicity of motor vehicle emission samples. Environ. Health Perspect. 100(2), 318-327.
12. Miller, C. A., Linak, W. P., King, C., and Wendt, J. O. L. (1998). Fine particle emissions from heavy fuel oil combustion in a firetube package boiler. Combust. Sci. Technol. 134, 477-502.
13. Morishita, M., Keeler, G., Wagner, J., Marsik, F., Timm, E., Dvonch, J., and Harkema, J. (2004). Pulmonary retention of particulate matter is associated with airway inflammation in allergic rats exposed to air pollution in urban Detroit. Inhal. Toxicol. 16, 663-674.
14. National Research Council. (2004). Air Quality Management in the United States. National Academy Press, Washington, DC.
15. Seagrave, J., McDonald, J. D., Bedrick, E., Edgerton, E. S., Gigliotti, A. P., Jansen, J. J., Ke, L., Naeher, L. P., Seilkop, S. K., Zheng, M., et al. (2006). Lung toxicity of ambient particulate matter from southeastern U.S. sites with different contributing sources: Relationships between composition and effects. Environ. Health Perspect. 114(9), 1387-1393.
16. Singh, P., DeMarini, D. M., Dick, C. A. J., Tabor, D. G., Ryan, J. V., Linak, W. P., Kobayashi, T., and Gilmour, M. I. (2004). Sample characterization of automobile and forklift diesel exhaust particles and comparative pulmonary toxicity in mice. Environ. Health Perspect 112, 820-825.
17. Thurston, G. D., Ito, K., Mar, T., Christensen, W. F., Eatough, D. J., Henry, R. C., Kim, E., Laden, F., Lall, R., Larson, T. V., et al. (2005). Workgroup report: Workshop on source apportionment of particulate matter health effects - Intercomparison of results and implications. Environ. Health Perspect. 113, 1768-1774.
18. U.S. Environmental Protection Agency. (2004). Air quality criteria for particulate matter (final version), EPA 600/P-99/002aF-bF, 2004.
19. U.S. Environmental Protection Agency. (2006a). Air quality criteria for ozone and related photochemical oxidants (final version) EPA/600/R-05/ 004aF-cF, 2006.
20. U.S. Environmental Protection Agency. (2006b). Air quality criteria for lead (final version), EPA/600/R-05/144aF-bF, 2006.
21. Venkatachari, P., Hopke, P. K., Brune, W. H., Ren, X., Lesher, R., Mao, J., and Mitchell, M. (2007). Characterization of wintertime reactive oxygen species concentrations in flushing, New York. Aerosol Sci. Technol. 41, 97-111.
22. Venkatachari, P., Hopke, P. K., Grover, B. D., and Eatough, D. J. (2005). Measurement of particle-bound reactive oxygen species in Rubidoux aerosols. J. Atmos. Chem. 50, 49-58.
23. Venkataraman, C., and Friedlander, S. K. (1994). Size distributions of polycyclic aromatic hydrocarbons and elemental carbon. 2. Ambient measurements and effects of atmospheric processes. Environ. Sci. Technol 28, 563-572.
24. Wellenius, G. A., Coull, B. A., Godleski, J. J., Koutrakis, P., Okabe, K., Savage, S. T., Lawrence, J. E., Murthy, G. G., and Verrier, R. L. (2003). Inhalation of concentrated ambient air particles exacerbates myocardial ischemia in conscious dogs. Environ. Health Perspect. 111, 402-408.