Mice with a targeted disruption of the Fgfrl1 gene die at birth due to alterations in the diaphragm

FEBS Journal

Volumn 274, Issue 23, 2007, Pages 6241-6253

  Baertschi, Stefan ^a   Zhuang, Lei ^a   Trueb, Beat ^a,b,c  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

^c ITI Research Institute   (Switzerland)

Author keywords

Diaphragm; Fibroblast growth factor (FGF); Fibroblast growth factor receptor (FGFR); Knockout mice; Muscle development

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 1; MUSCLE PROTEIN; MYOD PROTEIN; MYOGENIC FACTOR 5; MYOGENIN; PROTEIN MEF2A; PROTEIN MEF2B; PROTEIN MEF2C; PROTEIN MEF2D; PROTEIN MRF4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIRTH; CELL CULTURE; CONTROLLED STUDY; DIAPHRAGM; FAST MUSCLE FIBER; GENE DISRUPTION; GENE TARGETING; MOUSE; MUSCLE DEVELOPMENT; MYOTUBE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY FAILURE; SKELETAL MUSCLE; SLOW MUSCLE FIBER;

ANIMALS; CELLS, CULTURED; DIAPHRAGM; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; MYOBLASTS; PARTURITION; PREGNANCY; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 5;

MUS;

EID: 36248966403     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.06143.x     Document Type: Article

References (35)

1. Itoh N Ornitz DM (2004) Evolution of the Fgf and Fgfr gene families. Trends Genet 20, 563 569.
2. Eswarakumar VP, Lax I Schlessinger J (2005) Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev 16, 139 149.
3. Bellot F, Crumley G, Kaplow JM, Schlessinger J, Jaye M Dionne CA (1991) Ligand-induced transphosphorylation between different FGF receptors. EMBO J 10, 2849 2854.
4. Ueno H, Gunn M, Dell K, Tseng A Jr. Williams L (1992) A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor. J Biol Chem 267, 1470 1476.
5. Pellegrini L (2001) Role of heparan sulfate in fibroblast growth factor signalling: a structural view. Curr Opin Struct Biol 11, 629 634.
6. Mohammadi M, Olsen SK Ibrahimi OA (2005) Structural basis for fibroblast growth factor receptor activation. Cytokine Growth Factor Rev 16, 107 137.
7. Dailey L, Ambrosetti D, Mansukhani A Basilico C (2005) Mechanisms underlying differential responses to FGF signaling. Cytokine Growth Factor Rev 16, 233 247.
8. Wilkie AO (2005) Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations. Cytokine Growth Factor Rev 16, 187 203.
9. Coumoul X Deng CX (2003) Roles of FGF receptors in mammalian development and congenital diseases. Birth Defects Res C Embryo Today 69, 286 304.
10. Wiedemann M Trueb B (2000) Characterization of a novel protein (FGFRL1) from human cartilage related to FGF receptors. Genomics 69, 275 279.
11. Kim I, Moon S-O, Yu K-H, Kim U-H Koh GY (2001) A novel fibroblast growth factor receptor-5 preferentially expressed in the pancreas. Biochim Biophys Acta 1518, 152 156.
12. Sleeman M, Fraser J, McDonald M, Yuan S, White D, Grandison P, Kumble K, Watson JD Murison JG (2001) Identification of a new fibroblast growth factor receptor, FGFR5. Gene 271, 171 182.
13. Wiedemann M Trueb B (2001) The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein. Biochim Biophys Acta 1520, 247 250.
14. Trueb B, Zhuang L, Taeschler S Wiedemann M (2003) Characterization of FGFRL1, a novel FGF receptor preferentially expressed in cartilage. J Biol Chem 278, 33857 33865.
15. Hayashi S, Itoh M, Taira S, Agata K Taira M (2004) Expression patterns of Xenopus FGF receptor-like 1/nou-darake in early Xenopus development resembles those of planarian nou-darake and Xenopus FGF8. Dev Dyn 230, 700 707.
16. Trueb B, Neuhauss SCF, Baertschi S, Rieckmann T, Schild C Taeschler S (2005) Fish possess multiple copies of fgfrl1, the gene for a novel FGF receptor. Biochim Biophys Acta 1727, 65 74.
17. Beyeler M Trueb B (2006) Fgfrl1, a fibroblast growth factor receptor-like gene, is found in the cephalochordate Branchiostoma floridae but not in the urochordate Ciona intestinalis. Comp Biochem Physiol B Biochem Mol Biol 145, 43 49.
18. Schild C Trueb B (2005) Aberrant expression of FGFRL1, a novel FGF receptor, in ovarian tumors. Int J Mol Med 16, 1169 1173.
19. Trueb B Taeschler S (2006) Expression of FGFRL1, a novel fibroblast growth factor receptor, during embryonic development. Intl J Mol Med 17, 617 620.
20. Weinstein M, Xu X, Ohyama K Deng CX (1998) FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 125, 3615 3623.
21. Clapcote SJ Roder JC (2005) Simplex PCR assay for sex determination in mice. Biotechniques 38, 702 706.
22. Agbulut O, Noirez P, Beaumont F Butler-Browne G (2003) Myosin heavy chain isoforms in postnatal muscle development of mice. Biol Cell 95, 399 406.
23. Allan DW Greer JJ (1997) Embryogenesis of the phrenic nerve and diaphragm in the fetal rat. J Comp Neurol 382, 459 468.
24. Burgess RW, Peterson KA, Johnson MJ, Roix JJ, Welsh IC O'Brien TP (2004) Evidence for a conserved function in synapse formation reveals Phr1 as a candidate gene for respiratory failure in newborn mice. Mol Cell Biol 24, 1096 1105.
25. Pownall ME, Gustafsson MK Emerson CP Jr. (2002) Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos. Annu Rev Cell Dev Biol 18, 747 783.
26. Naya FJ Olson E (1999) MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation. Curr Opin Cell Biol 11, 683 688.
27. Silberstein L, Webster SG, Travis M Blau HM (1986) Developmental progression of myosin gene expression in cultured muscle cells. Cell 46, 1075 1081.
28. Ornitz DM (2005) FGF signaling in the developing endochondral skeleton. Cytokine Growth Factor Rev 16, 205 213.
29. Hall C, Flores MV, Murison G, Crosier K Crosier P (2006) An essential role for zebrafish Fgfrl1 during gill cartilage development. Mech Dev 123, 925 940.
30. Babiuk RP, Zhang W, Clugston R, Allan DW Greer JJ (2003) Embryological origins and development of the rat diaphragm. J Comp Neurol 455, 477 487.
31. Buckingham M, Bajard L, Chang T, Daubas P, Hadchouel J, Meilhac S, Montarras D, Rocancourt D Relaix F (2003) The formation of skeletal muscle: from somite to limb. J Anat 202, 59 68.
32. Inanlou MR, Dhillon GS, Belliveau AC, Reid GA, Ying C, Rudnicki MA Kablar B (2003) A significant reduction of the diaphragm in mdx: MyoD-/-(9th) embryos suggests a role for MyoD in the diaphragm development. Dev Biol 261, 324 336.
33. Rudnicki MA, Braun T, Hinuma S Jaenisch R (1992) Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development. Cell 71, 383 390.
34. Oh J, Takahashi R, Adachi E, Kondo S, Kuratomi S, Noma A, Alexander DB, Motoda H, Okada A et al. (2004) Mutations in two matrix metalloproteinase genes, MMP-2 and MT1-MMP, are synthetic lethal in mice. Oncogene 23, 5041 5048.
35. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA Struhl K (1987) Current Protocols in Molecular Biology. Greene Publishing Associates, New York, NY.