Hyperglycemia After Infant Cardiac Surgery Does Not Adversely Impact Neurodevelopmental Outcome

Annals of Thoracic Surgery

Volumn 84, Issue 6, 2007, Pages 2052-2058

  Ballweg, Jean A ^a   Wernovsky, Gil ^a   Ittenbach, Richard F ^a   Bernbaum, Judy ^a   Gerdes, Marsha ^a   Gallagher, Paul R ^a   Dominguez, Troy E ^a   Zackai, Elaine ^a   Clancy, Robert R ^a   Nicolson, Susan C ^a   Spray, Thomas L ^a   Gaynor, J William ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

ARTICLE; CHILD DEVELOPMENT; CONGENITAL HEART DISEASE; FEMALE; GLUCOSE BLOOD LEVEL; HEART SURGERY; HUMAN; HYPERGLYCEMIA; INFANT; MAJOR CLINICAL STUDY; MALE; MENTAL DEVELOPMENT; PEDIATRIC SURGERY; PRIORITY JOURNAL; PSYCHOMOTOR DEVELOPMENT; TREATMENT OUTCOME;

APOLIPOPROTEIN E2; BLOOD GLUCOSE; CARDIAC SURGICAL PROCEDURES; CHILD DEVELOPMENT; FEMALE; HEART DEFECTS, CONGENITAL; HUMANS; HYPERGLYCEMIA; INFANT; INFANT, NEWBORN; MALE; NEUROPSYCHOLOGICAL TESTS; POSTOPERATIVE COMPLICATIONS; PSYCHOMOTOR PERFORMANCE;

EID: 36248955597     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2007.06.099     Document Type: Article

References (37)

1. Bellinger D.C., Jonas R.A., Rappaport L.A., et al. Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. N Engl J Med 332 (1995) 549-555
2. Bellinger D.C., Wypji D., Kuban K.C., et al. Developmental and neurological status of children at 4 years of age after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. Circulation 100 (1999) 526-532
3. Bellinger D.C., Wypij D., du Plessis A.J., et al. Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: the Boston circulatory arrest trial. J Thorac Cardiovasc Surg 126 (2003) 1385-1396
4. Bellinger D.C., Wypij D., du Plessis A.J., et al. Developmental and neurologic effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants. J Thorac Cardiovasc Surg 121 (2001) 374-383
5. Newburger J.W., Wypij D., Bellinger D.C., et al. Length of stay after infant heart surgery is related to cognitive outcome at age 8 years. J Pediatr 143 (2003) 67-73
6. Jonas R.A., Wypij D., Roth S.J., et al. The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: Results of a randomized trial in infants. J of Thorac Cardiovasc Surg 126 (2003) 1765-1774
7. Gaynor J.W., Wernovsky G., Jarvik G.P., et al. Patient characteristics are important determinants of neurodevelopmental outcome at one-year of age following neonatal and infant cardiac surgery. J Thorac Cardiovasc Surg (2007) in press
8. Licht D.J., Wang J., Silvestre D.W., et al. Preoperative cerebral blood flow is diminished in neonates with severe congenital heart defects. J Thorac Cardiovasc Surg 128 (2004) 841-849
9. Galli K.K., Zimmerman R.A., Jarvik G.P., et al. Periventricular leukomalacia is common after neonatal cardiac surgery. J Thorac Cardiovasc Surg 127 (2004) 692-704
10. Capes S.E., Hunt D., Malmberg K., and Gerstein H.C. Stress hyperglycemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet 355 (2000) 773-778
11. Foo K., Cooper J., Deaner A., et al. A single serum glucose measurement predicts adverse outcomes across the whole range of acute coronary syndromes. Heart 89 (2003) 512-516
12. Malmberg K., and DIGAMI Diabetes Mellitus Insulin Glucose Infusion in Acute Myocardial Infarction Study Group. Prospective randomize study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus. B Med J 314 (1997) 1512-1515
13. Malmberg K., Norhammar A., Wedel H., and Ryden L. Glycometabolic state at admission: important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction: long-term results from the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) study. Circulation 99 (1999) 2626-2632
14. Wahab N.N., Cowden E.A., Pearce N.J., Gardner M.J., Merry H., Cox J.L., and ICONS Investigators. Is blood glucose an independent predictor or mortality in acute myocardial infarction in the thrombolytic era?. J Amer Coll Cardio 40 (2002) 1748-1754
15. Capes S.E., Hunt D., Mamberg K., Pathak P., and Gerstein H.C. Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview. Stroke 32 (2001) 2426-2432
16. Williams L.S., Rotich J., Qi R., et al. Effects of admission hyperglycemia on mortality and costs in acute ischemic stroke. Neurology 59 (2002) 67-71
17. Guvener M., Pasaoglu I., Demircin M., and Oc M. Perioperative hyperglycemia is a strong correlate of postoperative infection in type II diabetic patients after coronary artery bypass grafting. Endocr J 49 (2002) 531-537
18. Rovlias A., and Kotsou S. The influence of hyperglycemia on neurological outcome in patients with severe head injury. Neurosurg 46 (2000) 335-342
19. Doenst T., Wijeysundera D., Karkouti K., et al. Hyperglycemia during cardiopulmonary bypass is an independent risk factor for mortality in patients undergoing cardiac surgery. J Thorac Cardiovasc Surg 130 (2005) 114e1-114e8
20. Quinn D.W., Pagano D., and Bonser R.S. Improved myocardial protection during coronary artery surgery with glucose-insulin-potassium: a randomized controlled trial. J Thorac Cardiovasc Surg 131 (2006) 34-42
21. Krinsley J.S. Effect of an intensive glucose management protocol on the mortality of critically ill adult patients. Mayo Clinic Proceedings 79 (2004) 992-1000
22. Van Den Berge G., Wouters P., Weekers F., et al. Intensive insulin therapy in critically ill patients. New Engl J Med 345 (2001) 1359-1367
23. De Ferranti S., Gauvreau K., Hickey P.R., et al. Intraoperative hyperglycemia during infant cardiac surgery is not associated with adverse neurodevelopmental outcomes at 1, 4 and 8 years. Anesthesiology 11 (2004) 345-352
24. Yates A.R., Dyke P.C., Taeed R., et al. Hyperglycemia is a marker for poor outcome in the postoperative pediatric cardiac patient. Pediatr Crit Care Med 7 (2006) 351-355
25. Gaynor J.W., Gerdes M., Zachai E.H., et al. Apolipoprotein E genotype and neurodevelopmental sequelae of infant cardiac surgery. J Thorac Cardiovasc Surg 126 (2003) 1736-1745
26. Hollingshead A. Four Factor Index of Social Status, in Department of Sociology (1975), Yale University, New Haven, Conn
27. Faustino E.V., and Apkon M. Persistent hyperglycemia in critically ill children. J Pediatrics 146 (2005) 30-34
28. Wintergerst K.A., Buckingham B., Gandrud L., Wondg B.J., Kache S., and Wilson D.M. Association of hypoglycemia, hyperglycemia, and glucose variability with morbidity and death in the pediatric intensive care unit. Pediatrics 118 (2006) 173-179
29. Srinivasan V., Spinella P.C., Drott H.R., Roth C.L., Helfaer M.A., and Nadkarni V. Association of timing, duration, and intensity of hyperglycemia with intensive care unit mortality in critically ill children. Pediatr Crit Care Med 5 (2004) 329-336
30. Nicolson S.C., Jobes D.R., Zucker H.A., Steven J.M., Schreiner M.S., and Betts E.K. The effect of administering or withholding dextrose in pre-bypass intravenous fluids on intraoperative blood glucose concentrations in infants undergoing hypothermic circulatory arrest. J Cardiothorac Vasc Anesth 6 (1992) 316-318
31. Aouifi A, Neidecker J, Vedrinne C, et al. Glucose versus lactated ringer's solution during pediatric cardiac surgery. J Cardiothorac and Vasc Anesth 1197; 11:411-14.
32. Ouattara A., Lecomte P., Le Manach Y., et al. Poor intraoperative blood glucose control is associated with a worsened hospital outcome after cardiac surgery in diabetic patients. Anesthesiology 103 (2005) 687-694
33. Sieber R.E., and Traystman R.J. Special issues: Glucose and the brain. Crit Care Med 20 (1992) 104-114
34. Callahan D.J., Engle M.J., and Volpe J.J. Hypoxic injury to developing glial cells: protective effect of high glucose. Pediatr Res 27 (1990) 186-190
35. Vannucci R.C., and Mujsce D.J. Effect of glucose on perinatal hypoxic-ischemic brain damage. Biol Neonate 62 (1992) 215-224
36. Hattori H., and Wasterlain C.G. Posthypoxic glucose supplement reduces hypoxic-ischemic brain damage in the neonatal rat. Ann Neurol 28 (1990) 122-128
37. Schurr A., West C.A., Reid K.H., Tseng M.T., Reiss S., and Rigor B.M. Increased glucose improves recovery of neuronal function after cerebral hypoxia in vitro. Brain Res 421 (1987) 135-139