Clinical characteristics and risk stratification in symptomatic and asymptomatic patients with Brugada syndrome: Multicenter study in Japan

Journal of Cardiovascular Electrophysiology

Volumn 18, Issue 12, 2007, Pages 1244-1251

  Takagi, Masahiko ^a   Yokoyama, Yasuhiro ^b   Aonuma, Kazutaka ^c   Aihara, Naohiko ^d   Hiraoka, Masayasu ^e  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL HOSPITAL ORGANIZATION DISASTER MEDICAL CENTER   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Cardiac arrest; Depolarization; Electrocardiography; Prognosis; Tachyarrhythmia

Indexed keywords

ADULT; ARTICLE; BRUGADA SYNDROME; CLINICAL ASSESSMENT; CONTROL GROUP; CONTROLLED STUDY; DISEASE MARKER; ELECTROCARDIOGRAM; FEMALE; FOLLOW UP; HEART ATRIUM FIBRILLATION; HEART VENTRICLE FIBRILLATION; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; STATISTICAL SIGNIFICANCE; SUDDEN DEATH; SYMPTOMATOLOGY; SYNCOPE;

BRUGADA SYNDROME; COMORBIDITY; DEATH, SUDDEN, CARDIAC; FEMALE; HUMANS; INCIDENCE; JAPAN; MALE; MIDDLE AGED; RISK ASSESSMENT; RISK FACTORS; SURVIVAL ANALYSIS; SURVIVAL RATE; VENTRICULAR FIBRILLATION;

EID: 36148991882     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.2007.00971.x     Document Type: Article

References (23)

1. Brugada P, Brugada J : Right bundle branch block, persistent ST segment elevation and sudden cardiac death: A distinct clinical and electrocardiographic syndrome. J Am Coll Cardiol 1992 20 : 1391 1396.
2. Brugada J, Brugada R, Brugada P : Right bundle-branch block and ST-segment elevation in leads V1 through V3: A marker for sudden death in patients without demonstrable structural heart disease. Circulation 1998 97 : 457 460.
3. Brugada J, Brugada P : Further characterization of the syndrome of right bundle branch block, ST segment elevation, and sudden cardiac death. J Cardiovasc Electrophysiol 1997 8 : 325 331.
4. Priori SG, Napolitano C, Gasparini M, Pappone C, Della Bella P, Giordano U, Bloise R, Giustetto C, De Nardis R, Grillo M, Ronchetti E, Faggiano G, Nastoli J : Natural history of Brugada syndrome: Insight for risk stratification and management. Circulation 2002 105 : 1342 1347.
5. Brugada J, Brugada R, Antzelevitch C, Towbin J, Nademanee K, Brugada P : Long-term follow-up of individuals with the electrocardiographic pattern of right bundle-branch block and ST-segment elevation in precordial leads V1 to V3. Circulation 2002 105 : 73 78.
6. Brugada J, Brugada R, Brugada P : Determinants of sudden cardiac death in individuals with the electrocardiographic pattern of Brugada syndrome and no previous cardiac arrest. Circulation 2003 108 : 3092 3096.
7. Eckardt L, Probst V, Smits JPP, Bahr ES, Wolpert C, Schimpf R, Wichter T, Boisseau P, Heinecke A, Breithardt G, Borggrefe M, LeMarec H, Bocker D, Wilde AAM : Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndrome. Circulation 2005 111 : 257 263.
8. Atarashi H, Ogawa S, Harumi K, Sugimoto T, Inoue H, Murayama M, Toyama J, Hayakawa H : Three-year follow-up of patients with right bundle branch block and ST segment elevation in the right precordial leads: Japanese registry of Brugada syndrome. J Am Coll Cardiol 2001 37 : 1916 1920.
9. Sakabe M, Fujiki A, Tani M, Nishida K, Mizumaki K, Inoue H : Proportion and prognosis of healthy people with coved or saddle-back type ST segment elevation in the right precordial leads during 10 years follow-up. Eur Heart J 2003 24 : 1488 1493.
10. Nademanee K, Veerakul G, Nimmannit S, Chaowakul V, Bhuripanyo K, Likittanasombat K, Tunsanga K, Kuasirikul S, Malasit P, Tansupasawadikul S, Tatsanavivat P : Arrhythmogenic marker for the sudden unexplained death syndrome in Thai men. Circulation 1997 96 : 2595 2600.
11. Miyazaki T, Mitamura H, Miyoshi S, Soejima K, Aizawa Y, Ogawa S : Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome. J Am Coll Cardiol 1996 27 : 1061 1070.
12. Fujiki A, Usui M, Nagasawa H, Mizumaki K, Hayashi H, Inoue H : ST segment elevation in the right precordial leads induced with class IC antiarrhythmic drugs: Insight into the mechanism of Brugada syndrome. J Cardiovasc Electrophysiol 1999 10 : 214 218.
13. Nagase S, Kusano KF, Morita H, Fujimoto Y, Kakishita M, Nakamura K, Emori T, Matsubara H, Ohe T : Epicardial electrogram of the right ventricular outflow tract in patients with the Brugada syndrome: Using the epicardial lead. J Am Coll Cardiol 2002 39 : 1992 1995.
14. Kanda M, Shimizu W, Matsuo K, Nagaya N, Taguchi A, Suyama K, Kurita T, Aihara N, Kamakura S : Electrophysiologic characteristics and implications of induced ventricular fibrillation in symptomatic patients with Brugada syndrome. J Am Coll Cardiol 2002 39 : 1799 1805.
15. Ikeda T, Sakurada H, Sakabe K, Sakata T, Takami M, Tezuka N, Nakae T, Noro M, Enjoji Y, Tejima T, Sugi K : Assessment of noninvasive markers in identifying patients at risk in the Brugada syndrome: Insight into risk stratification. J Am Coll Cardiol 2001 37 : 1628 1634.
16. Ajiro Y, Hagiwara N, Kasanuki H : Assessment of markers for identifying patients at risk for life-threatening arrhythmic events in Brugada syndrome. J Cardiovasc Electrophysiol 2005 16 : 45 51.
17. Atarashi H, Ogawa S : Idiopathic Ventricular Fibrillation Investigator: New ECG criteria for high-risk Brugada syndrome. Circ J 2003 67 : 8 10.
18. Pitzalis MV, Anaclerio M, Iacoviello M, Forleo C, Guida P, Troccoli R, Massari F, Mastropasqua F, Sorrentino S, Manghisi A, Rizzon P : QT- interval prolongation in right precordial leads: An additional electrocardiographic hallmark of Brugada syndrome. J Am Coll Cardiol 2003 42 : 1632 1637.
19. Antzelevitch C : The Brugada syndrome: Diagnostic criteria and cellular mechanisms. Eur Heart J 2001 22 : 356 363.
20. Yan GX, Antzelevitch C : Cellular basis for the Brugada syndrome and other mechanisms of arrhythmmogenesis associated with ST-segment elevation. Circulation 1999 100 : 1660 1666.
21. Gehi AK, Duong TD, Metz LD, Gomes JA, Mehta D : Risk stratification of individuals with the Brugada electrocardiogram: A meta-analysis. J Cardiovasc Electrophysiol 2006 17 : 577 583.
22. Priori SG, Napolitano C : Should patients with an asymptomatic Brugada electrocardiogram undergo pharmacological and electrophysiological testing? Circulation 2005 112 : 285 291 discussion 279-292.
23. Tatsumi H, Takagi M, Nakagawa E, Yamashira H, Yoshiyama M : Risk stratification in patients with Brugada syndrome: Analysis of daily fluctuation in 12-lead electrocardiogram and signal-averaged electrocardiogram. J Cardiovasc Electrophysiol 2006 17 : 705 711.