Adherence to HAART therapy measured by electronic monitoring in newly diagnosed HIV patients in Botswana

European Journal of Clinical Pharmacology

Volumn 63, Issue 12, 2007, Pages 1115-1121

  Vriesendorp, Reinout ^a   Cohen, Adam ^a,e   Kristanto, Paulus ^c,d   Vrijens, Bernard ^c,d   Rakesh, Pande ^b   Anand, Bene ^b   Iwebor, Henry Uchechukwaka ^b   Stiekema, Jacobus ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Nyangabgwe Hospital   (Botswana)

^c Pharmionic Systems Ltd   (Belgium)

^d AARDEX Group   (Switzerland)

^e CENTRE FOR HUMAN DRUG RESEARCH   (Netherlands)

Author keywords

Adherence; HAART; MEMS CAPS

Indexed keywords

EFAVIRENZ; LAMIVUDINE PLUS ZIDOVUDINE; NEVIRAPINE;

ADULT; ARTICLE; BOTSWANA; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DEVICE; DRUG MONITORING; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; MICRE ELECTRO MECHANICAL SYSTEM; PHARMACY; PRIORITY JOURNAL; SELF REPORT;

ADULT; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BOTSWANA; DRUG MONITORING; ELECTRONICS; FEMALE; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; PATIENT COMPLIANCE; PILOT PROJECTS; SELF ADMINISTRATION;

EID: 36148977529     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-007-0369-2     Document Type: Article

References (29)

1. Weiser S, Wolfe W, Bangsberg D, Thior I, Gilbert P, Makhema J et al (2003) Barriers to antiretroviral adherence for patients living with HIV infection and AIDS in Botswana. J Acquir Immune Defic Syndr 34(3):281-288
2. de Korte DF, Darkoh E, Mazonde P, Soni A, Hazelwood J, Narasimhan F et al (2004) Strategies for a national AIDS treatment programme in Botswana. ACHAP Program Reviews 1(1):1-11
3. Palella FJ Jr, Delaney KM, Moorman AC, Loveless MO, Fuhrer J, Satten GA et al (1998) Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 338(13):853-860
4. Hogg RS, Heath KV, Yip B, Craib KJ, O'Shaughnessy MV, Schechter MT et al (1998) Improved survival among HIV-infected individuals following initiation of antiretroviral therapy. JAMA 279(6):450-454
5. DOHMH (2005) DOHMH recommendations for treating at-risk patients. AIDS Alert 20(4):39
6. Masquelier B, Pereira E, Peytavin G, Descamps D, Reynes J, Verdon R et al (2005) Intermittent viremia during first-line, protease inhibitors-containing therapy: significance and relationship with drug resistance. J Clin Virol 33(1):75-78
7. Paterson DL, Swindells S, Mohr J, Brester M, Vergis EN, Squier C et al (2000) Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med 133(1):21-30
8. Vanhove GF, Schapiro JM, Winters MA, Merigan TC, Blaschke TF (1996) Patient compliance and drug failure in protease inhibitor monotherapy. JAMA 276(24):1955-1956
9. Montaner JS, Reiss P, Cooper D, Vella S, Harris M, Conway B et al (1998) A randomized, double-blind trial comparing combinations of nevirapine, didanosine, and zidovudine for HIV-infected patients: the INCAS Trial. Italy, The Netherlands, Canada and Australia Study. JAMA 279(12):930-937
10. Schwed A, Fallab CL, Burnier M, Waeber B, Kappenberger L, Burnand B et al (1999) Electronic monitoring of compliance to lipid-lowering therapy in clinical practice. J Clin Pharmacol 39(4):402-409
11. Bova CA, Fennie KP, Knafl GJ, Dieckhaus KD, Watrous E, Williams AB (2005) Use of electronic monitoring devices to measure antiretroviral adherence: practical considerations. AIDS Behav 9(1):103-110
12. Paterson DL, Potoski B, Capitano B (2002) Measurement of adherence to antiretroviral medications. J Acquir Immune Defic Syndr 31(suppl 3):S103-S106
13. Dunbar-Jacob J, Erlen JA, Schlenk EA, Ryan CM, Sereika SM, Doswell WM (2000) Adherence in chronic disease. Annu Rev Nurs Res 18:48-90
14. Farmer KC (1999) Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice. Clin Ther 21(6):1074-1090
15. Burney KD, Krishnan K, Ruffin MT, Zhang DW, Brenner DE (1996) Adherence to single daily dose of aspirin in a chemoprevention trial. An evaluation of self-report and microelectronic monitoring. Arch Fam Med 5(5):297-300
16. Farmer KC (1999) Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice. Clin Ther 21(6):1074-1090
17. Frick PA, Gal P, Lane TW, Sewell PC (1998) Antiretroviral medication compliance in patients with AIDS. Aids Patient Care Stds 12(6):463-470
18. Liu HH, Golin CE, Miller LG, Hays RD, Beck K, Sanandaji S et al (2001) A comparison study of multiple measures of adherence to HIV protease inhibitors. Ann Intern Med 134(10):968-977
19. Schwed A, Fallab CL, Burnier M, Waeber B, Kappenberger L, Burnand B et al (1999) Electronic monitoring of compliance to lipid-lowering therapy in clinical practice. J Clin Pharmacol 39(4):402-409
20. Wagner GJ, Rabkin JG (2000) Measuring medication adherence: are missed doses reported more accurately then perfect adherence? AIDS Care 12(4):405-408
21. Paterson DL, Swindells S, Mohr J, Brester M, Vergis EN, Squier C et al (2000) Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med 133(1):21-30
22. Farley J, Hines S, Musk A, Ferrus S, Tepper V (2003) Assessment of adherence to antiviral therapy in HIV-infected children using the Medication Event Monitoring System, pharmacy refill, provider assessment, caregiver self-report, and appointment keeping. J Acquir Immune Defic Syndr 33(2):211-218
23. Chamot E, Coughlin SS, Farley TA, Rice JC (1999) Gonorrhea incidence and HIV testing and counseling among adolescents and young adults seen at a clinic for sexually transmitted diseases. AIDS 13(8):971-979
24. Jonsson EN, Wade JR, Almqvist G, Karlsson MO (1997) Discrimination between rival dosing histories. Pharm Res 14(8):984-991
25. Kruse W, Weber E (1990) Dynamics of drug regimen compliance-its assessment by microprocessor-based monitoring. Eur J Clin Pharmacol 38(6):561-565
26. Vrijens B, Tousset E, Rode R, Bertz R, Mayer S, Urquhart J (2005) Successful projection of the time course of drug concentration in plasma during a 1-year period from electronically compiled dosing-time data used as input to individually parameterized pharmacokinetic models. J Clin Pharmacol 45(4):461-467
27. Vrijens B, Goetghebeur E, de Klerk E, Rode R, Mayer S, Urquhart J (2005) Modelling the association between adherence and viral load in HIV-infected patients. Stat Med 24(17):2719-2731
28. Paterson DL, Swindells S, Mohr J, Brester M, Vergis EN, Squier C et al (2000) Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med 133(1):21-30
29. Conway B, Wainberg MA, Hall D, Harris M, Reiss P, Cooper D et al (2001) Development of drug resistance in patients receiving combinations of zidovudine, didanosine and nevirapine. AIDS 15(10):1269-1274