Multi-dimensional population balance modeling of the growth of rod-like L-glutamic acid crystals using growth rates estimated from in-process imaging

Advanced Powder Technology

Volumn 18, Issue 6, 2007, Pages 707-723

  Ma, Cai Y ^a   Wang, Xue Z ^a   Roberts, Kevin J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Crystal growth; Crystallization; Image analysis; In process imaging; L glutamic acid; Morphology; Population balance

Indexed keywords

CRYSTAL GROWTH; IMAGE ANALYSIS; IMAGING TECHNIQUES; MORPHOLOGY; PARAMETER ESTIMATION; PARTICLE SIZE; SUPERSATURATION;

CRYSTAL SHAPE; GROWTH RATES; PARTICLE SHAPE; POPULATION BALANCE;

CRYSTALLIZATION;

EID: 36148967732     PISSN: 09218831     EISSN: 15685527     Source Type: Journal    
DOI: 10.1163/156855207782514932     Document Type: Conference Paper

References (45)

1. F. Puel, G. Fevotte and J. P. Klein, Simulation and analysis of industrial crystallization processes through multidimensional population balance equations. Part 1: a resolution algorithm based on the method of classes, Chem. Eng. Sci. 58, 3715-3727 (2003).
2. F. Puel, G. Fevotte and J. P. Klein, Simulation and analysis of industrial crystallization processes through multidimensional population balance equations. Part 2: a study of semi-batch crystallization, Chem. Eng. Sci. 58, 3729-3740 (2003).
3. F. Puel, P. Marchal and J. Klein, Habit transient analysis in industrial crystallization using two dimensional crystal sizing technique, Chem. Eng. Res. Des. 75, 193-205 (1997).
4. D. L. Ma, D. K. Tafti and R. D. Braatz, High-resolution simulation of multidimensional crystal growth, Ind. Eng. Chem. Res. 41, 6217-6223 (2002).
5. H. Briesen, Simulation of crystal size and shape by means of a reduced two-dimensional population balance model, Chem. Eng. Sci. 61, 104-112 (2006).
6. P. Barrett and B. Glennon, Characterizing the metastable zone width and solubility curve using lasentec FBRM and PVM, Chem. Eng. Res. Des. 80, 799-805 (2002).
7. H. Y. Qu, M. Louhi-Kultanen and J. Kallas, In-line image analysis on the effects of additives in batch cooling crystallization, J. Cryst. Growth 289, 286-294 (2006).
8. J. W. Gerristen, R. Li, R. Penchev, X. Z. Wang, K. J. Roberts and R. J. Tweedie, Online shape analysis of particles using an in-situ vision system, presented at: Control of Particulate Processes VII, Harrison Hot Springs, British Columbia (2006).
9. M. J. Wilkinson, K. H. Jennings and M. Hardy, Non-invasive video imaging for interrogating pharmaceutical crystallization processes, Microsc. Microanal. 6, 996-997 (2000).
10. D. M. Scott, A. Boxman and C. E. Jochen, In-line particle characterization, Part. Part. Syst. Character. 15, 47-50 (1998).
11. M. J. Wilkinson, K. H. Jennings, R. Plant, R. Logan and B. Drayson, Particle size and shape measured for process monitoring using high-speed image analysis, presented at: Particulate Systems Analysis - 2003, Harrogate (2003).
12. D. B. Patience and J. B. Rawlings, Particle-shape monitoring and control in crystallization processes, AICHE J. 47, 2125-2130 (2001).
13. N. Laitinen, A. Osmo and J. Yliruusi, Characterization of particle sizes in bulk pharmaceutical solids using digital image information, AAPS PharmSciTech 4, 383-391 (2003).
14. J. Calderon de Anda, X. Z. Wang, X. Lai and K. J. Roberts, Classifying organic crystals via in-process image analysis and the use of monitoring charts to follow polymorphic and morphological changes, J. Process Control 15, 785-797 (2005).
15. J. Calderon de Anda, X. Z. Wang, X. Lai, K. J. Roberts, K. H. Jennings, M. J. Wilkinson, D. Watson and D. Roberts, Real-time product morphology monitoring in crystallization using imaging technique, AICHE J. 51, 1406-1414 (2005).
16. J. Calderon de Anda, X. Z. Wang and K. J. Roberts, Multi-scale segmentation image analysis for the in-process monitoring of particle shape with batch crystallisers, Chem. Eng. Sci. 60, 1053-1065 (2005).
17. X. Wang, J. Calderon de Anda, K. J. Roberts, R. F. Li, G. B. Thomson and G. White, Advances in on-line monitoring and control of the morphological and polymorphic forms of organic crystals grown from solution, KONA 23, 69-85 (2005).
18. X. Z. Wang, J. Calderon de Anda and K. J. Roberts, Real-time measurement of the growth rates of individual crystal facets using imaging and image analysis: a feasibility study on needle-shaped crystals of L-glutamic acid, Chem. Eng. Res. Des. 85, 921-927 (2007).
19. S. N. Black and D. L. Gray, Sensors and science in crystallisation of pharmaceuticals, presented at: 7th World Congress of Chemical Engineering, Glasgow, Scotland (2005).
20. E. Kougoulos, A. G. Jones, K. H. Jennings and M. W. Wood-Kaczmar, Use of focused beam reflectance measurement (FBRM) and process video imaging (PVI) in a modified mixed suspension mixed product removal (MSMPR) cooling crystallizer, J. Cryst. Growth 273, 529-534 (2005).
21. P. A. Larsen, J. B. Rawlings and N. J. Ferner, An algorithm for analyzing noisy, in situ images of high-aspect-ratio crystals to monitor particle size distribution, Chem. Eng. Sci. 61, 5236-5248 (2006).
22. J. Scholl, D. Bonalumi, L. Vicum, M. Mazzotti and M. Muller, In situ monitoring and modeling of the solvent-mediated polymorphic transformation of L-glutamic acid, Cryst. Growth Des. 6, 881-891 (2006).
23. Y. Zhou, X. T. Doan and R. Srinivasan, Real-time imaging and product quality characterization for control of particulate processes, in: Joint 16th ESCAPE and 9th PSE: Computer-Aided Chemical Engineering 21A, W. Marquardt and C. Pantelides (Eds), pp. 775-780. Elsevier, Garmisch-Partenkirchen (2006).
24. S. Dharmayat, J. C. De Anda, R. B. Hammond, X. J. Lai, K. J. Roberts and X. Z. Wang, Polymorphic transformation of L-glutamic acid monitored using combined on-line video microscopy and X-ray diffraction, J. Cryst. Growth 294, 35-40 (2006).
25. K. Pollanen, A. W. Hakkinen, S. P. Reinikainen, A. Louhi-Kultanen and L. Nystrom, A study on batch cooling crystallization of sulphathiazole - process monitoring using ATR-FTIR and product characterization by automated image analysis, Chem. Eng. Res. Des. 84, 47-59 (2006).
26. R. F. Li, G. B. Thomson, G. White, X. Z. Wang, J. C. De Anda and K. J. Roberts, Integration of crystal morphology modeling and on-line shape measurement, AICHE J. 52, 2297-2305 (2006).
27. R. David, P. Marchai and B. Marcant, Modeling of agglomeration in industrial crystallization from solution, Chem. Eng. Technol. 18, 302-309 (1995).
28. R. Franck, R. David, J. Villermaux and J. P. Klein, Crystallization and precipitation engineering. A chemical-reaction engineering approach to salicylic-acid precipitation - modeling of batch kinetics and application to continuous operation, Chem. Eng. Sci. 43, 69-77 (1988).
29. M. J. Hounslow and J. W Wynn, Short-cut models for particulate processes, Comput. Chem. Eng 17, 505-516 (1993).
30. A. W. Mahoney and D. Ramkrishna, Efficient solution of population balance equations with discontinuities by finite elements, Chem. Eng. Sci. 57, 1107-1119 (2002).
31. P. Marchai, R. David, J. P. Klein and J. Villermaux, Crystallization and precipitation engineering. 1. An efficient method for solving population balance in crystallization with agglomeration, Chem. Eng. Sci. 43, 59-67 (1988).
32. H. Muhr, R. David, J. Villermaux and P. H. Jezequel, Crystallization and precipitation engineering. 6. Solving population balance in the case of the precipitation of silver bromide crystals with high primary nucleation rates by using the first order upwind differentiation, Chem. Eng. Sci. 51, 309-319 (1996).
33. M. Nicmanis and M. J. Hounslow, Finite-elements methods for steady state population balance equations, AICHE J. 44, 2258-2272 (1998).
34. J. B. Rawlings, W. R. Witkowski and J. W. Eaton, Modelling and control of crystallizers, Powder Technol. 69, 3-9 (1992).
35. J. A. Wojcik and A. G. Jones, Dynamics and stability of continuous MSMPR agglomerative precipitation: numerical analysis of the dual co-ordinate model, Comput. Chem. Eng. 22, 535-545 (1998).
36. R. David, J. Villermaux, P. Marchal and J.-P. Klein, Crystallisation and percipitation engineering - IV Kinetic model of adipic acid crystallisation, Chem. Eng. Sci. 46, 1129-1136 (1991).
37. L. F. Shampine and H. A. Watts, Subroutine RKF45, in: Computer Methods for Mathematical Computations, M. A. M. G. E. Forsythe and C. B. Moler (Eds), pp. 135-147. Prentice-Hall, Englewood Cliffs, NJ (1977).
38. J. Garside, Industrial crystallization from solution, Chem. Eng. Sci. 40, 3-26 (1985).
39. M. Kitamura and T. Ishizu, Growth kinetics and morphological change of polymorphs of L-glutamic acid, J. Cryst. Growth 209, 138-145 (2000).
40. J. W. Mullin, Crystallization. Butterworth-Heinemann, Boston, MA (2001).
41. A. Randolph and M. A. Larson, Theory of Particulate Processes: Analysis and Techniques of Continuous Crystallization. Academic Press, London (1988).
42. W. K. Burton, N. Cabrera and F. C. Frank, The growth of crystals and the equilibrium structure of their surfaces, Philos. Trans. R. Soc. Lond. 243, 299-358 (1951).
43. G. H. Gilmer and P. Bennema, Computer simulation of crystal surface-structure and growth kinetics, J. Cryst. Growth 13, 148-152 (1971).
44. IO Industries, http://www.ioindustries.com/vs.htm (2007).
45. P. Mougin, D. Wilkinson and K. J. Roberts, In situ measurement of particle size during the crystallization of L-glutamic acid under two polymorphic forms: influence of crystal habit on ultrasonic attenuation measurements, Cryst. Growth Des. 2, 227-234 (2002).