Convenient total synthesis of taranabant (MK-0364), a novel cannabinoid-1 receptor inverse agonist as an anti-obesity agent

Tetrahedron

Volumn 63, Issue 52, 2007, Pages 12845-12852

  Kim, Min ah ^a   Kim, Jong Yup ^a   Song, Kwang Seop ^a   Kim, Jeongmin ^a   Lee, Jinhwa ^a  

^a Green Cross Company   (South Korea)

Author keywords

Anti obesity; Evans asymmetric reaction; Hydride reduction; Taranabant

Indexed keywords

ANTIOBESITY AGENT; CANNABINOID RECEPTOR AGONIST; MK 0364; N[4 (4 CHLOROPHENYL) 3 (3 BROMOPHENYL)BUTAN 2 YL] 2 METHYL 2 (5 TRIFLUOROMETHYLPYRIDIN 2 YLOXY)PROPANAMIDE; TARANABANT; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHIRALITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG MARKETING; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOSELECTIVITY; FOOD AND DRUG ADMINISTRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOCHEMISTRY;

EID: 36148954684     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2007.10.056     Document Type: Article

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