Evidence for dimethyl sulphoxide (DMSO) use in horses. Part 1: DMSO as a topical and intra-articular anti-inflammatory agent

Equine Veterinary Education

Volumn 19, Issue 10, 2007, Pages 545-546

  Schleining, J A ^a   Reinertson, E L ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EQUIDAE;

EID: 36148946686     PISSN: 09577734     EISSN: None     Source Type: Journal    
DOI: 10.2746/095777307X248641     Document Type: Article

References (11)

1. Adair, H.S., Goble, D.O., Vanhooser, S., Blackford, J.T. and Rohrbach, B.W. (1991) Evaluation of use of dimethyl sulfoxidefor intra-articular lavage in clinically normal horses. Am. J. vet Res. 52, 333-336.
2. Auer, D.E., Ng, J.C., Reilly, J.S. and Seawright, A.A. (1991) Anti-inflammatory drugs inhibit degradation of equine synovial fluid induced by free radicals. Aust. vet. J. 68, 403-405.
3. Brayton, C.F. (1986) Dimethyl sulfoxide (DMSO): A review. Cornell Vet. 76, 61-90.
4. Koller, L.D. (1976) Clinical application of DMSO by veterinarians in Oregon and Washington. Vet. Med. small anim. Clin. 71, 591-577.
5. Levesque, F. (1967) Effects of DMSO on open wounds in horses. Ann. N. Y. Acad. Sci. 141, 490-492.
6. Moses, V.S., Hardy, J., Bertone, A.L. and Weisbrode, S.E. (2001) Effects of anti-inflammatory drugs on lipopolysaccharide-challenged and - unchallenged equine synovial explants. Am. J. vet. Res. 62, 54-60.
7. Smith, C.L., MacDonald, M.H., Tesch, A.M. and Willits, N.H. (2000) In vitro evaluation of the effect of dimethyl sulfoxide on equine articular cartilage matrix metabolism. Vet. Surg. 29, 347-357.
8. Smith, G., Bertone, A.L., Kaeding, C., Simmons, E.J. and Apostoles, S. (1998) Anti-inflammatory effects of topically applied dimethyl sulfoxide gel on endotoxin-induced synovitis in horses. Am. J. vet. Res. 59, 1149-1152.
9. Teigland, M.B. and Saurino, V.R. (1967) Clinical evaluation of dimethyl sulfoxide in equine applications. Ann. N. Y. Acad. Sci. 141, 471-477.
10. Welch, R.D., DeBowes, R.M. and Liepold, H.W. (1989) Evaluation of the effects of intra-articular injection of dimethylsulfoxide on normal equine articular tissues. Am. J. vet. Res. 50, 1180-1182.
11. Welch, R.D., Watkins, J.P., DeBowes, R.M. and Leipold, H.W. (1991) Effects of intra-articular administration of dimethylsulfoxide on chemically induced synovitis in immature horses. Am. J. vet. Res. 52, 934-939.