In vitro evaluation of the effect of dimethyl sulfoxide on equine articular cartilage matrix metabolism

Veterinary Surgery

Volumn 29, Issue 4, 2000, Pages 347-357

  Smith, Christine L ^a   Macdonald, Melinda H ^a   Tesch, Anthony M ^a   Willits, Neil H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; DIMETHYL SULFOXIDE; LACTIC ACID; PROTEOGLYCAN;

ANIMAL; ANIMAL DISEASE; ARTHROPATHY; ARTICLE; ARTICULAR CARTILAGE; BIOSYNTHESIS; CARTILAGE CELL; CELL SURVIVAL; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; HORSE; HORSE DISEASE; LAVAGE; METABOLISM;

ANALGESICS, NON-NARCOTIC; ANIMALS; CARTILAGE, ARTICULAR; CELL SURVIVAL; CHONDROCYTES; CULTURE TECHNIQUES; DIMETHYL SULFOXIDE; HORSE DISEASES; HORSES; IRRIGATION; JOINT DISEASES; LACTIC ACID; PROTEOGLYCANS;

EID: 0034221864     PISSN: 01613499     EISSN: None     Source Type: Journal    
DOI: 10.1053/jvet.2000.5607     Document Type: Article

References (43)

1. Brayton CF: Dimethyl sulfoxide (DMSO): A review. Cornell Vet 76:61-90, 1986
2. Haigler HJ, Spring DD: Comparison of the analgesic effects of dimethyl sulfoxide and morphine. Ann NY Acad Sci 411: 19-27, 1983
3. Fox RB, Fox WK: Dimethyl sulfoxide prevents hydroxyl radical-mediated depolymerization of hyaluronic acid. Ann NY Acad Sci 411:14-18, 1983
4. Wooley RE, Gilbert JP, Shotts EB: Inhibitory effects of combinations of oxytetracycline, dimethyl sulfoxide and EDTA-tromethamine on Escherichia coli. Am J Vet Res 42:2010-2013, 1981
5. Wooley RE, Gilbert JP, Shotts EB: Antibacterial action of combinations of oxytetracycline, dimethyl sulfoxide, EDTA-tromethamine on Proteus, Salmonella, Aeromonas. Am J Vet Res 43:130-133, 1982
6. Welch RD, DeBowes RM, Liepold HW: Evaluation of the effects of intra-articular injection of dimethylsulfoxide on normal equine articular tissues. Am J Vet Res 50:1180-1182, 1989
7. Welch RD, Watkins JP, DeBowes RM, et al: Effects of intra-articular administration of dimethylsulfoxide on chemically induced synovitis in immature horses. Am J Vet Res 52:934-939, 1991
8. Rubin LF: Toxicologic update of dimethyl sulfoxide. Ann NY Acad Sci 411:6-10, 1983
9. Adair HS, Goble DO, VanHooser S, et al: Evaluation of use of dimethyl sulfoxide for intra-articular lavage in clinically normal horses. Am J Vet Res 52:333-336, 1991
10. Honnas, CM, Welch RD, Ford TS, et al: Septic arthritis of the distal interphalangeal joint in 12 horses. Vet Surg 21:261-268, 1992
11. Smith G, Bertone AL, Kaeding C, et al: Anti-inflammatory effects of topically applied dimethyl sulfoxide gel on endotoxin induced synovitis in horses. Am J Vet Res 59:1149-1152, 1998
12. Auer DE, Ng JC, Reilly JS, et al: Anti-inflammatory drugs inhibit degradation of equine synovial fluid induced by free radicals. Aust Vet J 68:403-405, 1991
13. Auer DE, Ng JC, Seawright AA: Superoxide production by stimulated equine polymorphonuclear leukocytes - Inhibition by anti-inflammatory drugs. J Vet Pharmacol Ther 13:59-66, 1990
14. Santos L, Tipping PG: Attenuation of adjuvant arthritis in rats by treatment with oxygen radical scavengers. Immunol Cell Biol 72:406-414, 1994
15. More RC, Kabo JM, Dorey FJ, et al: The effects of dimethyl sulfoxide on posttraumatic limb swelling and joint stiffness. A review and an experimental study in rabbits. Clin Orthop 233:304-309, 1988
16. Matthews GL, Engler SJ, Morris EA: Effect of dimethylsulfoxide on articular cartilage proteoglycan synthesis and degradation, chondrocyte viability, and matrix water content. Vet Surg 27:438-444, 1998
17. Palmer JL, Bertone AL: Joint structure, biochemistry and biochemical disequilibrium in synovitis and equine joint disease. Equine Vet J 26:263-276, 1994
18. Burkhardt H, Schwingel M, Menninger H, et al: Oxygen radicals as effectors of cartilage destruction. Direct degradative effect on matrix components and indirect action via activation of latent collagenase from polymorphonuclear leukocytes. Arthritis Rheum 29:379-387, 1986
19. Auer DE, Ng JC, Seawright AA: Free radical oxidation products in plasma and synovial fluid of horses with synovial inflammation. Aust Vet J 70:49-52, 1993
20. Martens RJ, Auer JA, Carter GK: Equine pediatrics: Septic arthritis and osteomyelitis. J Am Vet Med Assoc 188:582-585, 1986
21. Schneider RK, Bramlage LR, Moore RM, et al: A retrospective study of 192 horses affected with septic arthritis/ tenosynovitis. Equine Vet J 24:436-442, 1992
22. Bertone AL: Infectious arthritis, in McIlwraith CW, Trotter GW (eds): Joint Disease in the Horse. Philadelphia, PA, Saunders, 1996, pp 397-409
23. Ingle-Fehr JE, Baxter GM: Endoscopy of the calcaneal bursa in horses. Vet Surg 27:561-567, 1998
24. MacDonald MH, Stover SM, Willits NH, et al: Regulation of matrix metabolism in equine cartilage explant cultures by interleukin 1. Am J Vet Res 53:2278-2285, 1992
25. Platt D, Bird JLE, Bayliss MT: Ageing of equine articular cartilage: Structure and composition of aggrecan and decorin. Equine Vet J 30:43-52, 1998
26. 2 synthesis in equine cartilage explant cultures. Am J Vet Res 55:1127-1138, 1994
27. Platt D: Isolated chondrocyte and cartilage explant culture systems as techniques to investigate the pathogenesis of equine joint disease, in McIlwraith CW, Trotter GW (eds): Joint Disease in the Horse. Philadelphia, PA, Saunders, 1996, pp 441-446
28. 2 from equine chondrocytes and cartilage explants. Am J Vet Res 60:89-104, 1999
29. Clegg PD, Burke RM, Coughlan AR, et al: Characterization of equine matrix metalloproteinase 2 and 9; and identification of the cellular sources of these enzymes in joints. Equine Vet J 29:335-342, 1997
30. Bird JL, Wells T, Bayliss MT: IL-1β induces the degradation of equine articular cartilage by a mechanism that is not mediated by nitric oxide. Biochem Biophys Res Commun 238:81-85, 1997
31. Glade MJ: Polysulphated glycosaminoglycan accelerates net synthesis of collagen and glycosaminoglycans by arthritic cartilage tissues and chondrocytes. Am J Vet Res 51:779-785, 1990
32. Ratcliffe A, Beauvais PJ, Saed-Nejad F: Differential levels of synovial fluid aggrecan aggregate components in experimental osteoarthritis and joint disuse. J Orthop Res 12:464-473, 1994
33. Farndale RW: A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures. Connect Tissue Res 9:247-248, 1982
34. Gloster JA, Harris P: Observations on an enzymatic method for the estimation of pyruvate in blood Clin Chim Acta 7:206-211, 1962
35. Kim Y-J, Sah RLY, Doong J-YH, et al: Fluorometric assay of DNA in cartilage explants using Hoescht 33258. Anal Biochem 174:168-176, 1988
36. Rago R, Mitchen J, Wilding G: DNA fluorometric assay in 96-well tissue culture plates using Hoescht 33258 after cell lysis by freezing in distilled water. Anal Biochem 191:31-34, 1990
37. Yang H, Acker J, Chen A, et al: In situ assessment of cell viability. Cell Transplant 7:443-451, 1998
38. Muldrew K, Hurtig M, Novak K, et al: Localization of freezing injury in articular cartilage. Cryobiology 31:31-38, 1994
39. Nixon AJ, Lust G, Vernier-Singer M: Isolation, propagation and cryopreservation of equine articular chondrocytes. Am J Vet Res 53:2364-2370, 1992
40. Tomford WW, Duff GP, Mankin HJ: Experimental freeze-preservation of chondrocytes. Clin Orthop 197:11-14, 1985
41. Desjardins MR, Hurtig MB, Palmer NC: Heterotopic transfer of fresh and cryopreserved autogenous articular cartilage in the horse. Vet Surg 20:434-435, 1991
42. Desjardins MR, Hurtig MB, Palmer NC: Incorporation of fresh and cryopreserved bone in osteochondral autografts in the horse. Vet Surg 20:446-452, 1991
43. Kawcak CE, Trotter GW, Frisbie DD, et al: Maintenance of equine articular cartilage explants in serum-free and serum-supplemented media, compared with that in a commercial supplemented medium. Am J Vet Res 57:1261-1265, 1996