A novel acetyl-CoA carboxylase inhibitor reduces de novo fatty acid synthesis in HepG2 cells and rat primary hepatocytes

Archives of Biochemistry and Biophysics

Volumn 468, Issue 1, 2007, Pages 44-48

  Sugimoto, Yoshinori ^a,b   Naniwa, Yoshimitsu ^a   Nakamura, Takayuki ^a   Kato, Hirotsugu ^a   Yamamoto, Masanori ^a   Tanabe, Hirofumi ^a   Inoue, Kinji ^b   Imaizumi, Atsushi ^a  

^a TEIJIN PHARMA LIMITED   (Japan)

^b SAITAMA UNIVERSITY   (Japan)

Author keywords

ACC; Fatty acid synthesis; Triglycerides

Indexed keywords

ACETIC ACID; ACETYL COENZYME A; ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A TRANSFERASE; BENZOFURAN DERIVATIVE; BENZOFURANYL ALPHA PYRONE; DIACYLGLYCEROL; FATTY ACID; FATTY ACID SYNTHASE; TEI B00422; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN HEPG2; COMPETITIVE INHIBITION; DRUG STRUCTURE; FATTY ACID SYNTHESIS; HUMAN; HUMAN CELL; LIPOGENESIS; LIVER CELL; METABOLIC DISORDER; NONHUMAN; PRIORITY JOURNAL; RAT;

ACETYL COENZYME A; ANIMALS; BENZOFURANS; CELL LINE; ENZYME INHIBITORS; FATTY ACIDS; HEPATOBLASTOMA; HEPATOCYTES; HUMANS; LIVER NEOPLASMS; PYRONES; RATS;

RATTUS;

EID: 36049029132     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2007.09.012     Document Type: Article

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